Scavenger receptor family proteins: Roles for atherosclerosis, host defence and disorders of the central nervous system

Cellular and Molecular Life Sciences

Volumn 54, Issue 7, 1998, Pages 628-640

  Yamada, Y ^a   Doi, T ^a   Hamakubo, T ^a   Kodama, T ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Alzheimer's disease; Apoptosis; Atherosclerosis; Cholesterol; Endothelial cell; Host defence; Lipoprotein metabolism; Macrophage

Indexed keywords

CD36 ANTIGEN; CD68 ANTIGEN; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN; SCAVENGER RECEPTOR;

ALZHEIMER DISEASE; APOPTOSIS; ATHEROSCLEROSIS; CELL ADHESION; CENTRAL NERVOUS SYSTEM DISEASE; CYTOPLASM; ENDOTHELIUM CELL; GENE FUNCTION; GENE STRUCTURE; HOST RESISTANCE; KNOCKOUT MOUSE; LIGAND BINDING; LIPOPROTEIN METABOLISM; LUNG DISEASE; MACROPHAGE; NONHUMAN; PHAGOCYTOSIS; REVIEW; T LYMPHOCYTE; XANTHOMATOSIS;

ANIMALS; ANTIGENS, CD36; ARTERIOSCLEROSIS; CELL ADHESION; CENTRAL NERVOUS SYSTEM; COLLAGEN; ENDOCYTOSIS; MACROPHAGES; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PHAGOCYTOSIS; RECEPTORS, IMMUNOLOGIC; RECEPTORS, LIPOPROTEIN; RECEPTORS, SCAVENGER; SCAVENGER RECEPTORS, CLASS A; SCAVENGER RECEPTORS, CLASS B; SCAVENGER RECEPTORS, CLASS E; XANTHOMATOSIS;

EID: 0031848185     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000180050191     Document Type: Review

References (136)

1. Goldstein J. L., Ho Y. K., Basu S. K. and Brown M. S. (1997) Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition. Proc. Natl. Acad. Sci. USA 76: 333-337
2. Brown M. S., Basu S. K., Falck J. R., Ho Y. K. and Goldstein J. L. (1980) The scavenger cell pathway for lipoprotein degradation: specificity of the binding site that mediates the uptake of negatively-charged LDL by macrophages. J. Supramol. Struct. 13: 67-81
3. Brown M. S. and Goldstein J. L. (1983) Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. Annu. Rev. Biochem. 52: 223-261
4. Brown M. S. and Goldstein J. L. (1990) Atherosclerosis. Scavenging for receptors. Nature 343: 508-509
5. Steinberg D., Parthasarathy S., Carew T. E., Khoo J. C. and Witztum J. L. (1989) Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 320: 915-924
6. Steinbrecher U. P., Parthasarathy S., Leake D. S., Witztum J. L. and Steinberg D. (1984) Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids. Proc. Natl. Acad. Sci. USA 81: 3883-3887
7. Haberland M. E., Fong D. and Cheng L. (1988) Malondialdehyde-altered protein occurs in atheroma of Watanabe heritable hyperlipidemic rabbits. Science 241: 215-218
8. Jurgens G., Hoff H. F., Chisolm G. M. III and Esterbauer H. (1987) Modification of human serum low density lipoprotein by oxidation-characterization and pathophysiological implications. Chem. Phys. Lipids 45: 315-336
9. Arai H., Kita T., Yokode M., Narumiya S. and Kawai C. (1989) Multiple receptors for modified low density lipoproteins in mouse peritoneal macrophages: different uptake mechanisms for acetylated and oxidized low densitylipoproteins. Biochem. Biophys. Res. Commun. 159: 1375-1382
10. Sparrow C. P., Parthasarathy S. and Steinberg D. (1989) A macrophage receptor that recognizes oxidized low density lipoprotein but not acetylated low density lipoprotein. J. Biol. Chem. 264: 2599-2604
11. Via D. P., Dresel H. A., Cheng S. L. and Gotto A. M. Jr. (1985) Murine macrophage tumors are a source of a 260,000-dalton acetyl-low density lipoprotein receptor. J. Biol. Chem. 260: 7379-7386
12. Kodama T., Reddy P., Kishimoto C., Krieger M. (1988) Purification and characterization of a bovine acetyl low density lipoprotein receptor. Proc. Natl. Acad. Sci. USA 85: 9238-9242
13. Kodama T., Freeman M., Rohrer L., Zabrecky J., Matsudaira P. and Krieger M. (1990) Type 1 macrophage scavenger receptor contains alpha-helical and collagen-like coiled coils. Nature 343: 531-535
14. Rohrer L., Freeman M., Kodama T., Penman M. and Krieger M. (1990) Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II. Nature 343: 570-572
15. Matsumoto A., Naito M., Itakura H., Ikemoto S., Asaoka II., Hayakawa I, et al. (1990) Human macrophage scavenger receptors: primary structure, expression and localization in atherosclerotic lesions. Proc. Natl. Acad. Sci. USA 87: 9133-9137
16. Doi T., Higashino K., Kurihara Y., Wada Y., Miyazaki P., Nakamura H, et al. (1993) Charged collagen structure mediates the recognition of negatively charged macromolecules by macrophage scavenger receptors. J. Biol. Chem. 268: 2126-2133
17. Acton S., Resnick D., Freeman M., Ekkel Y., Ashkenas J. and Krieger M. (1993) The collagenous domains of macrophage scavenger receptors and complement component Clq mediate their similar, but not identical, binding specificities forpolyanionic ligands. J. Biol. Chem. 268: 3530-3537
18. Kodama T., Doi T., Suzuki H., Takahashi K., Wada Y. and Gordon S. (1996) Collagenous macrophage scavenger receptors. Curr. Opin. Lipidol. 7: 287-291
19. Krieger M. and Herz J. (1994) Structure and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related proteins. Annu. Rev. Biochem. 63: 601-37
20. Freeman M., Ashkenas J., Rees D. J., Kingsley D. M., Copeland N. G., Jenkins N. A. et al. (1990) An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors. Proc. Natl. Acad. Sci. USA 87: 8810-8814
21. Resnick D., Pearson A. and Krieger M. (1994) The SRCR superfamily: a family reminiscent of the Ig superfamily. Trends Biochem. Sci. 19: 5-8
22. Elomaa O., Kangas M., Sahlberg C., Tuukkanen J., Sormunen R., Liakka A, et al. (1995) Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages. Cell 80: 603-609
23. Endemann G., Stanton L. W., Madden K. S., Bryant C. M., White R. T. and Protter A. A. (1993) CD36 is a receptor for oxidized low density lipoprotein. J. Biol. Chem. 268: 11811-11816
24. Acton S. L., Scherer P. E., Lodish H. F. and Krieger M. (1994) Expression cloning of SR-BI, a CD36-related class B scavenger receptor. J. Biol. Chem. 269: 21003-21009
25. Daviel L., McGregor J. L. (1997) Vascular biology of CD36: roles of this new adhesion molecule family in different disease states. Thromb. Haemost. 78: 65-69
26. Krieger M. (1992) Molecular flypaper and atherosclerosis: structure of the macrophage scavenger receptor. Trends Biochem. Sci. 17: 141-146
27. Rigotti A., Trigatti B., Babitt J., Penman M., Xu S. and Krieger M. (1997) Scavenger receptor BI a cell surface receptor for high density lipoprotein. Curr. Opin. Lipidol. 8: 181-188
28. Acton S., Rigotti A., Landschulz K. T., Xu S., Hobbs H. H. and Krieger M (1996) Identification of scavenger receptor SR-BI as a high-density lipoprotein receptor. Science 271: 518-520
29. Rigotti A., Acton S. L. and Krieger M. (1995) The class B scavenger receptors SR-BI and CD36 are receptors for anionic phospholipids. J. Biol. Chem. 270: 16221-16224
30. Rigotti A., Edelman E. R., Seifert P., Iqbal S. N., DeMattos R. B., Temel R. E. et al. (1996) Regulation by adrenocorticotropic hormone of the in vivo expression of scavenger receptor class B type I (SR-BI), a high density lipoprotein receptor, in steroidogenic cells of the murine adrenal gland. J. Biol. Chem. 271: 33545-33549
31. Kozarsky K. F., Donahee M. H., Rigotti A., Iqbal S. N., Edelman E. R. and Krieger M. (1997) Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels. Nature 387: 414-417
32. Ramprasad M. P., Fischer W., Witztum J. L., Sambrano G. R., Quehenberger O. and Steinberg D. (1995) The 94- to 97-kDa mouse macrophage membrane protein that recognizes oxidized low density lipoprotein and phosphatidylserine-rich liposomes is identical to macrosialin, the mouse homologue of human CD68. Proc. Natl. Acad. Sci. USA 92: 9580-9584
33. Holness C. L., da Silva R. P., Fawcett J., Gordon S. and Simmons D. L. (1993) Macrosialin, a mouse macrophage-restricted glycoprotein, is a member of the 1amp/1gp family. J. Biol. Chem. 268: 9661-9666
34. Pearson A., Lux A. and Krieger M. (1995) Expression cloning of dSR-Cl, a class C macrophage-specific scavenger receptor from Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 92: 4056-4060
35. Sawamura T., Kume N., Aoyama T., Moriwaki H., Hoshikawa H. and Aiba Y, et al. (1997) An endothelial receptor for oxidized low-density lipoprotein. Nature 386: 73-77
36. Stanton L. W., White R. T., Bryant C. M., Protter A. A. and Endemann G. (1992) A macrophage Fc receptor for IgG is also a receptor for oxidized low density lipoprotein. J. Biol. Chem. 267: 22446-22451
37. Suzuki H., Kurihara Y., Takeya M., Kamada N., Kataoka M., Jishage K. et al. (1997) A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection. Nature 386: 292-296
38. Naito M., Kodama T., Matsumoto A., Doi T. and Takahashi K. (1991) Tissue distribution, intracellular localization, and in vitro expression of bovine macrophage scavenger receptors. Am. J. Pathol. 139: 1411-1423
39. Bell M. D., Lopez-Gonzalez R., Lawson L., Hughes D., Fraser L, Gordon S. and Perry V. H. (1994) Upregulation of the macrophage scavenger receptor in response to different forms of injury in the CNS. J. Neurocytol. 23: 605-613
40. Mato M., Ookawara S., Sakamoto A., Aikawa F., Ogawa T., Mitsuhashi U. et al. (1996) Involvement of specific macrophage-lineage cells surrounding arterioles in barrier and scavenger function in brain cortex. Proc. Natl. Acad. Sci. USA 93: 3269-3274
41. Christie R. H., Freeman M. and Hyman B. T. (1996) Expression of the macrophage scavenger receptor, a multifunctional lipoprotein receptor, in microglia associated with senile plaques in Alzheimer's disease. Am. J. Pathol. 148: 399-403
42. El Khoury J., Hickman S. E., Thomas C. A., Cao L., Silverstein S. C. and Loike J. D. (1996) Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils. Nature 382: 716-719
43. Emi M., Asaoka H., Matsumoto A., Itakura H., Kurihara Y. and Wada Y. (1993) Structure, organization and chromosomal mapping of the human macrophage scavenger receptor gene. J. Biol. Chem. 268: 2120-2125
44. Naito M., Suzuki H., Mori T., Matsumoto A., Kodama T. and Takahashi K. (1992) Coexpression of type I and type II human macrophage scavenger receptors in macrophages of various organs and foam cells in atherosclerotic lesions. Am. J. Pathol. 141: 591-599
45. Geng Y. J. and Haussen G. K. (1995) High endothelial cells of postcapillary venules express the scavenger receptor in human peripheral lymph nodes. Stand. J. Immunol. 42: 289-296
46. de Villiers W. J., Fraser I. P., Hughes D. A., Doyle A. G. and Gordon S. (1994) Macrophage-colony-stimulating factor selectively enhances macrophage scavenger receptor expression and function. J. Exp. Med. 180: 705-709
47. de Villiers W. J., Fraser I. P. and Gordon S. (1994) Cytokine and growth factor regulation of macrophage scavenger receptor expression and function. Immunol. Lett. 43: 73-79
48. Geng Y. J. and Hansson G. K. (1992) Interferon-gamma inhibits scavenger receptor expression and foam cell formation in human monocyte-derived macrophages. J. Clin. Invest. 89: 1322-1330
49. Geng Y., Kodama T. and Hansson G. K. (1994) Differential expression of scavenger receptor isoforms during monocyte-macrophage differentiation and foam cell formation. Arterioscler. Thromb. 14: 798-806
50. Moulton K. S., Wu H., Barnett J., Parthasarathy S. and Glass C. K. (1992) Regulated expression of the human acetylated low density lipoprotein receptor gene and isolation of promoter sequences. Proc. Natl. Acad. Sci. USA 1992 89: 8102-8106
51. Wu H., Moulton K., Horvai A., Parik S. and Glass C. K. (1994) Combinatorial interactions between AP-1 and ets domain proteins contribute to the developmental regulation of the macrophage scavenger receptor gene. Mol. Cell. Biol. 14: 2129-2139
52. Moulton K. S., Semple K., Wu H. and Glass C. K. (1994) Cell-specific expression of the macrophage scavenger receptor gene is dependent on PU.1 and a composite AP-1 ets motif. Mol. Cell. Biol. 14: 4408-4418
53. Horvai A., Palinski W., Wu H., Moulton K. S., Kalla K. and Glass C. K. (1995) Scavenger receptor A gene regulatory elements target gene expression to macrophages and to foam cells of atherosclerotic lesions. Proc. Natl. Acad. Sci. USA 92: 5391-5395
54. Horvai A. E.,. Xu L., Korzus E., Brard G., Kalafus D. and Mullen T. M. (1997) Nuclear integration of JAK STAT and Ras AP-1 signaling by CBP and p300. Proc. Natl. Acad. Sci. USA 94: 1074-1079
55. Aftring R. P. and Freeman M. W. (1995) Structure of the murine macrophage scavenger receptor gene and evaluation of sequences that regulate expression in the macrophage cell line. P388D. J. Lipid Res. 36: 1305-1314
56. Liao H. S., Kodama T., Doi T., Emi M., Asaoka H., Itakura H. et al. (1997) Novel elements located at -504 to -399 bp of the promoter region regulated the expression of the human macrophage scavenger receptor gene in murine macrophages. J. Lipid Res. 38: 1433-1444
57. Pitas R. E. (1990) Expression of the acetyl low density lipoprotein receptor by rabbit fibroblasts and smooth muscle cells. Up-regulation by phorbol esters. J. Biol. Chem. 265: 12722-12727
58. Pitas R. E., Friera A., McGuire J. and Dejager S. (1992) Further characterization of the acetyl LDL (scavenger) receptor expressed by rabbit smooth muscle cells and fibroblasts. Arterioscler. Thromb. 12: 1235-1244
59. Bickel P. E. and Freeman M. W. (1992) Rabbit aortic smooth muscle cells express inducible macrophage scavenger receptor messenger RNA that is absent from endothelial cells. J. Clin. Invest. 90: 1450-1457
60. Mietus-Snyder M., Friera A., Glass C. K. and Pitas R. F. (1997) Regulation of scavenger receptor expression in smooth muscle cells by protein kinase C: a role for oxidative stress. Arterioscler. Thromb. Vasc. Biol. 17: 969-978
61. Li H., Freeman M. W. and Libby P. (1995) Regulation of smooth muscle cell scavenger receptor expression in vivo by atherogenic diets and in vitro by cytokines. J. Clin. Invest. 95: 122-133
62. Inaba T., Gotoda T., Shimano H., Shimada M., Harada K., Kozaki K. et al. (1992) Platelet-derived growth factor induces c-fms and scavenger receptor genes in vascular smooth muscle cells. J. Biol. Chem. 267: 13107-13112
63. Inaba T., Gotoda T., Harada K., Shimada M., Ohsuga J., Ishibashi S. et al. (1995) Induction of sustained expression of proto-oncogene c-fms by platelet-derived growth factor, epidermal growth factor, and basic fibroblast growth factor, and its suppression by interferon-gamma and macrophage colony-stimulating factor in human aortic medial smooth muscle cells. J. Clin. Invest. 95: 1133-1139
64. Gong Q. and Pitas R. L. (1995) Synergistic effects of growth factors on the regulation of smooth muscle cell scavenger receptor activity. J. Biol. Chem. 270: 21672-21678
65. Resnick D., Chatterton J. E., Schwartz K., Slayter H. and Krieger M. (1996) Structures of class A macrophage scavenger receptors. Electron microscopic study of flexible, multidomain, fibrous proteins and determination of the disulfide bond pattern of the scavenger receptor cysteine-rich domain. J. Biol. Chem. 271: 26924-26930
66. Tanaka T., Wada Y., Nakamura H., Doi T., Imanishi T. and Kodama T. (1993) A synthetic model of collagen structure taken from bovine macrophage scavenger receptor. FEBS Lett. 334: 272-276
67. Tanaka T., Nishikawa A., Tanaka Y., Nakamura H., Kodama T., Imanishi T. et al. (1996) Synthetic collagen-like domain derived from the macrophage scavenger receptor binds acetylated low-density lipoprotein in vitro. Protein Eng. 9: 307-313
68. Bodian D. L., Skonier J. E., Bowen M. A., Neubauer M., Siadak A. W., Aruffo A. et al. (1997) Identification of residues in CD6 which are critical for ligand binding. Biochemistry 36: 2637-2641
69. Doi T., Kurasawa M., Higashino K., Imanishi T., Mori T. and Naito M. et al. (1994) The histidine interruption of an alpha-helical coiled coil allosterically mediates a pH-dependent ligand dissociation from macrophage scavenger receptors. J. Biol. Chem. 269: 25598-25604
70. Fraser I., Hughes D. and Gordon S. (1993) Divalent cation-independent macrophage adhesion inhibited by monoclonal antibody to murine scavenger receptor. Nature 364: 343-346
71. Wada Y., Doi T., Matsumoto A., Asaoka H., Honda M., Hatano H. et al. (1995) Structure and function of macrophage scavenger receptors. Ann. NY Acad. Sci. 748: 226-238
72. Lougheed M., Lum C. M., Ling W., Suzuki H., Kodama T. and Steinbrecher U. (1997) High affinity saturable uptake of oxidized low density lipoprotein by macrophages from mice lacking the scavenger receptor class A type I/II. J. Biol. Chem. 272: 12938-12944
73. Ling W., Lougheed M., Suzuki H., Buchan A., Kodama T. and Steinbrecher V. P. (1997) Oxidized or acetylated low density lipoproteins are rapidly cleared by the liver in mice with disruption of the scavenger receptor class A type I/II gene. J. Clin. Invest. 100: 244-252
74. Platt N., Suzuki H., Kurihara Y., Kodama T. and Gordon S. (1996) Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro. Proc. Natl. Acad. Sci. USA 93: 12456-12460
75. Terpstra V., Kondratenko N. and Steinberg D. (1997) Macrophages lacking scavenger receptor A show a decrease in binding and uptake of acetylated low-density lipoprotein and of apoptotic thymocytes, but not of oxidatively damaged red blood cells. Proc. Natl. Acad. Sci. USA 94: 8127-8131
76. Ren Y., Silverstein R. L., Allen J. and Savill J. (1995) CD36 gene transfer confers capacity for phagocytosis of cells undergoing apoptosis. J. Exp. Med. 181: 1857-1862
77. Sambrano G. R., Parthasarathy S. and Steinberg D. (1994) Recognition of oxidatively damaged erythrocytes by a macrophage receptor with specificity for oxidized low density lipoprotein. Proc. Natl. Acad. Sci. USA 91: 3265-3269
78. Sambrano G. R. and Steinberg D. (1995) Recognition of oxidatively damaged and apoptotic cells by an oxidized low density lipoprotein receptor on mouse peritoneal macrophages: role of membrane phosphatidylserine. Proc. Natl. Acad. Sci. USA 92: 1396-1400
79. Auger M. J. and Ross J. A. (1991) The biology of the macrophages. In: The Macrophage, pp. 1-74, Lewis C. E. L. and McGee J. O'D (eds). IRL Press, Oxford
80. Hampion R. Y., Golenbock D. T., Penman M., Krieger M. and Raetz C. R. (1991) Recognition and plasma clearance of endotoxin by scavenger receptors. Nature 352: 342-344
81. Dunne D. W., Resnick D., Greenberg J., Krieger M. and Joiner K. A. (1994) The type I macrophage scavenger receptor binds to gram-positive bacteria and recognizes lipoteichoic acid. Proc. Natl. Acad. Sci. USA 91: 1863-1867
82. Mato M, Ookawara S. and Kurihara K. (1980) Uptake of exogenous substances and marked infoldings of the fluorescent granular pericyte in cerebral fine vessels. Am. J. Anat. 157: 329-332
83. Knowles D. M. H, Tolidjian B., Marboe C., D'Agati V., Grimes M. and Chess L. (1984) Monoclonal anti-human monocyte antibodies OKM1 and OKM5 possess distinctive tissue distributions including differential reactivity with vascular endothelium. J. Immunol. 132: 2170-2173
84. Mato M., Ookawara S. and Sakamoto A. (1997) Growth retardation of Mato's fluorescent granular perithelial (FGP) cells in scavenger receptor knockout (SRKO) mice. Anat. Rec. 247: 307-316
85. Perry V. H. (1994) Modulation of microglia phenotype. Neuropathol. Appl. Neurobiol. 20: 177
86. Perry V. H. and Andersson P. B. (1992) The inflammatory response in the CNS. Neuropathol. Appl. Neurobiol. 18: 454-459
87. Bell M. D., Lopez-Gonzalez R., Lawson L., Hughes D., Fraser I., Gordon S. et al. (1994) Upregulation of the macrophage scavenger receptor in response to different forms of injury in the CNS. J. Neurocytol. 23: 605-613
88. Okumura T. and Jamieson G. A. (1976) Platelet glycocalicin-orientation of glycoproteins of the human platelet surface. J. Biol. Chem. 251: 5944-5949
89. Yesner L. M., Huh H. Y., Pearce S. F. and Silverstein R. L. (1996) Regulation of monocyte CD36 and thrombospondin-1 expression by soluble mediators. Arterioscler. Thromb. Vasc. Biol. 16: 1019-1025
90. Huh H. Y., Lo S. K., Yesner L. M. and Silverstein R. L. (1995) CD36 induction on human monocytes upon adhesion to tumor necrosis factor-activated endothelial cells. J. Biol. Chem. 270: 6267-6271
91. Armesilla A. L., Calvo D. and Vega M. A. (1996) Structural and functional characterization of the human CD36 gene promoter: identification of a proximal PEBP2/CBF site. J. Biol. Chem. 271: 7781-7787
92. Lisanti M. P., Scherer P. E., Vidugiriene J., Tang Z., Hermanowski-Vosatka A. et al. (1994) Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease. J. Cell. Biol. 126: 111-126
93. Smart E. J., Ying Y. S., Donzell W. C. and Anderson R. G. (1996) A role for caveolin in transport of cholesterol from endoplasmic reticulum to plasma membrane. J. Biol. Chem. 271: 29427-29435
94. Fielding P. H. and Fielding C. J. (1995) Plasma membrane caveolae mediate the efflux of cellular free cholesterol. Biochemistry 34: 14288-14292
95. Landschulz K. T., Pathak R. K., Rigotti A., Krieger M. and Hobbs H. H. (1996) Regulation of scavenger receptor, class B., type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat. J. Clin. Invest. 98: 984-995
96. Babitt J., Trigatti B., Rigotti A., Smart E. J., Anderson R. G., Xu S. et al. (1997) Murine SR-BI, a high density lipoprotein receptor that mediates selective lipid uptake, is N-glycosylated and fatty acylated and colocalizes with plasma membrane caveolae. J. Biol. Chem. 272: 13242-13249
97. Murao K., Terpstra V., Green S. R., Kondratenko N., Steinberg D. and Quehenberger O. (1997) Characterizalion of CLA-1, a human homologue of rodent scavenger receptor B1, as a receptor for high density lipoprotein and apoptotic thymocytes. J. Biol. Chem. 272: 17551-17557
98. Tao N., Wagner S. J. and Lublin D. M. (1996) CD36 is palmitoylated on both N- and C-terminal cytoplasmic tails. J. Biol. Chem. 271: 22315-22320
99. Daviel L., Morel-Kopp M. C., Kaplan C. and McGregor J. L. (1995) A structural functional domain on human CD36 is involved in the binding of anti-Nak(a) antibodies. Thromb. Haemost. 73: 543-545
100. Abumrad N. A., el-Maghrabi M. R., Amri E. Z., Lopez E. and Grimaldi P. A. (1993) Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36. J. Biol. Chem. 268: 17665-17668
101. Navazo M. D., Daviet L., Ninio E. and McGregor J. L. (1996) Identification on human CD36 of a domain (155-183) implicated in binding oxidized low-density lipoproteins (Ox-LDL). Arterioscler. Thromb. Vasc. Biol. 16: 1033-1039
102. Greenwalt D. E., Scheck S. H. and Rhinehart-Jones T. (1995) Heart CD36 expression is increased in murine models of diabetes and in mice fed a high fat diet. J. Clin. Invest. 96: 1382-1388
103. Yamamoto N., Akamatsu N., Sakuraba H., Yamazaki H. and Tanoue K. (1994) Platelet glycoprotein IV (CD36) deficiency is associated with the absence (type I) or the presence (type II) of glycoprotein IV on monocytes. Blood 83: 392-397
104. Kashiwagi H., Honda S., Tomiyama Y., Mizutani H., Take H. and Honda Y. et al. (1993) A novel polymorphism in glycoprotein IV (replacement of proline-90 by serine) predominates in subjects with platelet GPIV deficiency. Thromb. Haemost. 69: 481-484
105. Kashiwagi H., Tomiyama Y., Honda S., Kosugi S., Shiraga M., Nagao N. et al. (1995) Molecular basis of CD36 deficiency. Evidence that a 478C→T substitution (proline90→serine) in CD36 cDNA accounts for CD36 deficiency. J. Clin. Invest. 95: 1040-1046
106. Nozaki S., Kashiwagi H., Yamashita S., Nakagawa T., Kostner B, and Tomiyama Y. et al. (1995) Reduced uptake of oxidized low density lipoproteins in monocyte-derived macrophages from CD36-deficient subjects. J. Clin. Invest. 96: 1859-1865
107. Tandon N. N., Ockenhouse C. F., Greco N. J. and Jamieson G. A. (1991) Adhesive functions of platelets lacking glycoprotein IV (CD36). Blood 78: 2809-2813
108. Oquendo P., Hundt E., Lawler J. and Seed B. (1989) CD36 directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Cell. 58: 95-101
109. Daviet L., Craig A. G., McGregor L., Pinches R., Wild T. F., Berendt A. R. et al. (1997) Characterization of two vaccinia CD36 recombinant-virus-generated monoclonal antibodies (10/5, 13/10): effects on malarial cytoadherence and platelet functions. Eur. J. Biochem. 243: 344-349
110. Baruch D. I., Pasloske B. L., Singh H. B., Bi X., Ma X. C., Feldman M. et al. (1995) Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes. Cell 82: 77-87
111. Ockenhouse C. F., Magowan C. and Chulay J. D. (1989) Activation of monocytes and platelets by monoclonal antibodies or malaria-infected erythrocytes binding to the CD36 surface receptor in vitro. J. Clin. Invest. 84: 468-475
112. Huang M. M., Bolen J. B., Barnwell J. W., Shattil S. J. and Brugge J. S. (1991) Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn and Yes protein-tyrosine kinases in human platelets. Proc. Natl. Acad. Sci. USA 88: 7844-7848
113. Ryeom S. W., Silverstein R. L., Scotto A. and Sparrow J. R. (1996) Binding of anionic phospholipids to retinal pigment epithelium may be mediated by the scavenger receptor CD36. J. Biol. Chem. 271: 20536-20539
114. Franc N. C., Dimarcq J. L., Lagueux M., Hoffmann J. and Ezekowitz R. A. (1996) Croquemort, a novel Drosophila hemocyte macrophage receptor that recognizes apoptotic cells. Immunity 4: 431-443
115. Wang N., Weng W., Breslow J. L. and Tall A. R. (1996) Scavenger receptor BI (SR-BI) is upregulated in adrenal gland in apolipoprotein A-I and hepatic lipase knock-out mice as a response to depletion of cholesterol stores. In vivo evidence that SR-BI is a functional high density lipoprotein receptor under feedback control. J. Biol. Chem. 271: 21001-21004
116. Rigotti A., Trigatti B. L., Penman M., Rayburn H., Hertz J. and Krieger M. (1997) A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism. Proc. Natl. Acad. Sci. USA 94: 12610-12615
117. Ottnad E., Parthasarathy S., Sambrano G. R., Ramprasad M. P., Quehenberger O. and Kondratenko N. et al. (1995) A macrophage receptor for oxidized low density lipoprotein distinct from the receptor for acetyl low density lipoprotein: partial purification and role in recognition of oxidatively damaged cells. Proc. Natl. Acad. Sci. USA 92: 1391-1395
118. de Rijke V. B. and van Berkel T. J. (1994) Rat liver Kupffer and endothelial cells express different binding proteins for modified low density lipoproteins. Kupffer cells express a 95-kDa membrane protein as a specific binding site for oxidized low density lipoproteins. J. Biol. Chem. 269(2): 824-827
119. Martinez-Pomares L., Platt N., McKnight A. J., da Silva R. P. and Gordon S. (1996) Macrophage membrane molecules: markers of tissue differentiation and heterogeneity. Immunobiology 195: 407-416
120. Ramprasad M. P., Terpstra V., Kondratenko N., Quehenberger O. and Steinberg D. (1996) Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein. Proc. Natl. Acad. Sci. USA 93: 14833-14838
121. Drickamer K. (1988) Two distinct classes of carbohydrate-recognition domains in animal lectins. J. Biol. Chem. 263: 9557-9560
122. Ravetch J. V., Luster A. D., Weinshank R., Kochan J., Pavlovec A. and Portnoy D. A. et al. (1986) Structural heterogeneity and functional domains of murine immunoglobulin G Fc receptors. Science 234: 718-725
123. Morganelli P. M., Groveman D. S. and Pfeiffer J. R. (1997) Evidence that human Fc gamma receptor 11A (CD32) subtypes are not receptors for oxidized LDL. Arterioscler. Thromb. Vasc. Biol. 17: 3248-3254
124. Luoma J., Hiltunen T., Sarkioja T., Moestrup S. K., Gliemann J. and Kodama T. (1994) Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and scavenger receptor in human atherosclerotic lesions. J. Clin. Invest. 93: 2014-2021
125. Yla-Herttuala S. (1996) Expression of lipoprotein receptors and related molecules in atherosclerotic lesions. Curr. Opin. Lipidol. 7: 292-297
126. Zhang S. H., Reddick R. L., Piedrahita J. A. and Maeda N. (1992) Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 258: 468-471
127. Sakai M., Miyazaki A., Hakamata H., Kodama T., Suzuki H., Kobori S. et al. (1996) The scavenger receptor serves as a route for internalization of lysophosphatidylcholine in oxidized low density lipoprotein-induced macrophage proliferation J. Biol. Chem. 271: 27346-27352
128. Sakaguchi H., Takeya M., Suzuki H., Hakamata H., Kodama T., Horiuchi S. et al. (1998) Role of macrophage scavenger receptors in diet-induced atherosclerosis in mice. Lab. Invest. 78: 423-434
129. Berliner J. A., Territo M. C., Sevanian A., Ramin S., Kim J. A., Bamshad B. et al. (1990) Minimally modified low density lipoprotein stimulates monocyte endothelial interactions. J. Clin. Invest. 85: 1260-1266
130. Paresce D. M., Ghosh R. N. and Maxfield F. R. (1996) Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor. Neuron 17: 553-565
131. Yan S. D., Chen X., Fu J., Chen M., Zhu H., Roher A. et al. (1996) RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease. Nature 382: 685-691
132. Araki N., Higashi T., Mori T., Shibayama R., Kawabe Y. and Kodama T. (1995) Macrophage scavenger receptor mediates the endocytic uptake and degradation of advanced glycation end products of the Maillard reaction. Eur. J. Biochem. 230: 408-415
133. Grewal R. P., Yoshida T., Finch C. E. and Morgan T. E. (1997) Scavenger receptor mRNAs in rat brain microglia are induced by kainic acid lesioning and by cytokines. Neuroreport 8: 1077-1081
134. Resnick D., Freedman N. J., Xu S. and Krieger M. (1993) Secreted extracellular domains of macrophage scavenger receptors form elongated trimers which specifically bind cidolite asbestos. J. Biol. Chem. 268: 3538-3545
135. Giry C., Giroux L. M., Roy M., Davignon J. and Minnich A. (1996) Characterization of inherited scavenger receptor over-expression and abnormal macrophage phenotype in a normolipidemic subject with planar xanthomas. J. Lipid Res. 37: 1422-1435
136. Furue M., Suzuki H., Kodama T., Hiramoto T., Sugiyama H. and Tamaki K. (1995) Colocalization of scavenger receptor in CD68 positive foam cells in verruciform xanthoma. J. Dermatol. Sci. 10: 213-219