Fatty streak formation occurs in human fetal aortas and is greatly enhanced maternal, hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atheroeclerotic lesions

Journal of Clinical Investigation

Volumn 100, Issue 11, 1997, Pages 2680-2690

  Napoli, Claudio ^a   D'Armiento, Francesco Paolo ^a   Mancini, Francesco Paolo ^a   Postiglione, Alfredo ^a   Witztum, Joseph L ^b   Palumbo, Giuseppe ^a   Palinski, Wulf ^b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Arteriosclerosis; Fetal development; Hypercholesterolemia; Lipoprotein oxidation; Macrophages

Indexed keywords

ALDEHYDE; APOLIPOPROTEIN B; CHOLESTEROL; EPITOPE; LOW DENSITY LIPOPROTEIN; MALONALDEHYDE; OXIDIZED LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL;

ABDOMINAL AORTA; AORTA ARCH; AORTA ATHEROSCLEROSIS; ARTICLE; ATHEROGENESIS; CONTROLLED STUDY; FETUS; GESTATIONAL AGE; HUMAN; HUMAN TISSUE; HYPERCHOLESTEROLEMIA; LIPID OXIDATION; MATERNAL DISEASE; MONOCYTE; NEWBORN; PRIORITY JOURNAL; THORACIC AORTA;

EID: 0031456505     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119813     Document Type: Article

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