SCOPUS 정보 검색 플랫폼

Current Opinion in Molecular Therapeutics

Volumn 2, Issue 4, 2000, Pages 448-452

Technology evaluation: Gene therapy (IL-2), Valentis Inc

(1) Morse, M A a

a DUKE UNIVERSITY MEDICAL CENTER (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CHOLESTEROL; CYTOKINE; INTERLEUKIN 12; INTERLEUKIN 2; LIPOFECTIN; LIPOSOME;

ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; GENE TECHNOLOGY; GENE THERAPY; HEAD AND NECK CARCINOMA; HUMAN; IMMUNOSTIMULATION; MELANOMA; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PLASMID;

ANIMALS; BIOTECHNOLOGY; DISEASE MODELS, ANIMAL; DNA, RECOMBINANT; GENE THERAPY; HEAD AND NECK NEOPLASMS; HUMANS; INTERLEUKIN-2; LIPOSOMES; NEOPLASMS;

EID: 0033838978 PISSN: 14648431 EISSN: None Source Type: Journal
DOI: None Document Type: Article

Times cited : (13)

References (25)

1
- 0027517321
- Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biological activity and lack of toxicity in humans
- (1993) Proc Natl Acad Sci U.S.A. , vol.90 , pp. 11307-11311
- Nabel, G.J.¹ Nabel, E.G.² Yang, Z.Y.³ Fox, B.A.⁴ Plautz, G.E.⁵ Gao, X.⁶ Huang, L.⁷ Shu, S.⁸ Gordon, D.⁹ Chang, A.E.¹⁰

2
- 0008262203
- GeneMedicine Inc: GeneMedicine commences IL-2 cancer GeneMedicine phase I clinical trial. Press release 21 August
- (1997)

3
- 0008224023
- GeneMedicine Inc: GeneMedicine receives $5.25 million from Corange under cancer alliance. Press release 10 February
- (1998)

4
- 0023447252
- Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure
- (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7413-7417
- Felgner, P.L.¹ Gadek, T.R.² Holm, M.³ Roman, R.⁴ Chan, H.W.⁵ Wenz, M.⁶ Northrop, J.P.⁷ Ringold, G.M.⁸ Danielsen, M.⁹

5
- 0008227629
- Non-viral IL-2 gene transfer with paracrine induction of IFNγ and IL-12 as a primary or combination therapy with surgery for head and neck cancer
- (1998) Am Soc Gene Ther , vol.134 a , pp. 536
- O'Malley, B.W.¹ Ralston, R.² Li, D.³ Munger, W.E.⁴ Bruno, M.⁵ Muller, S.⁶ Pericle, F.⁷ Schaumberg, J.P.⁸ McQuone, S.⁹

6
- 0025095664
- Interleukin-2 production by tumor cells bypasses T-helper function in the generation of an antitumor response
- (1990) Cell , vol.60 , pp. 397-403
- Fearon, E.R.¹ Pardoll, D.M.² Itaya, T.³ Golumbek, P.⁴ Levitsky, H.I.⁵ Simons, J.W.⁶ Karasuyama, H.⁷ Vogelstein, B.⁸ Frost, P.⁹

7
- 0008261474
- GeneMedicine Inc: GeneMedicine initiates phase I/II clinical trials using interferon-α gene therapy. Press release 16 March
- (1999)

8
- 17344373047
- Non-viral interferon-α gene therapy inhibits growth of established tumors by eliciting a systemic immune response
- (1998) Hum Gene Ther , vol.9 , pp. 2223-2230
- Coleman, M.¹ Muller, S.² Quezada, A.³ Mendiratta, S.K.⁴ Wang, J.⁵ Thull, N.M.⁶ Bishop, J.⁷ Matar, M.⁸ Mester, J.⁹ Pericle, F.¹⁰

9
- 0008184905
- Valentis Inc: Valentis Inc initiates phase II clinical trial with interleukin-2 gene medicine. Press release 29 June
- (1999)

10
- 0032552426
- Biodistribution and gene expression of lipid/plasmid complexes after systemic administration
- (1998) Hum Gene Ther , vol.9 , pp. 2083-2099
- Mahato, R.I.¹ Anwer, K.² Tagliaferri, F.³ Meaney, C.⁴ Leonard, P.⁵ Wadhwa, M.S.⁶ Logan, M.⁷ French, M.⁸ Rolland, A.⁹

11
- 0008190138
- Valentis Inc: Valentis Inc initiates phase I/II clinical trial with interleukin-12 gene therapy. Press release 21 July
- (1999)

12
- 0033585425
- Contribution of plasmid DNA to inflammation in the lung after administration of cationic lipid:pDNA complexes
- (1999) Hum Gene Ther , vol.10 , pp. 223-234
- Yew, N.S.¹ Wang, K.X.² Przybylska, M.³ Bagley, R.G.⁴ Stedman, M.⁵ Marshall, J.⁶ Scheule, R.K.⁷ Cheng, S.H.⁸

13
- 17344362631
- Cationic phosphonolipids as non-viral gene transfer agents in the lungs of mice
- (1998) Hum Gene Ther , vol.9 , pp. 2309-2319
- Guillaume-Gable, C.¹ Floch, V.² Mercier, B.³ Audrezet, M.P.⁴ Gobin, E.⁵ Le Bolch, G.⁶ Yaouanc, J.J.⁷ Clement, J.C.⁸ Des Abbayes, H.⁹ Leroy, J.P.¹⁰ Morin, V.¹¹ Ferec, C.¹²

14
- 13144265730
- Lipitoids - Novel cationic lipids for cellular delivery of plasmid DNA in vitro
- (1998) Chem Biol , vol.5 , pp. 345-354
- Huang, C.Y.¹ Uno, T.² Murphy, J.E.³ Lee, S.⁴ Hamer, J.D.⁵ Escobedo, J.A.⁶ Cohen, F.E.⁷ Radhakrishnan, R.⁸ Dwarki, V.⁹ Zuckermann, R.N.¹⁰

15
- 0032962975
- Metabolic instability of plasmid DNA in the cytosol: A potential barrier to gene transfer
- (1999) Gene Ther , vol.6 , pp. 482-497
- Lechardeur, D.¹ Sohn, K.J.² Haardt, M.³ Joshi, P.B.⁴ Monck, M.⁵ Graham, R.W.⁶ Beatty, B.⁷ Squire, J.⁸ O'Brodovich, H.⁹ Lukacs, G.L.¹⁰

16
- 0033018932
- Combination surgery and non-viral interleukin-2 gene therapy for head and neck cancer
- (1999) Clin Cancer Res , vol.5 , pp. 1551-1556
- Li, D.¹ Jiang, W.² Bishop, J.S.³ Ralston, R.⁴ O'Malley, B.W.⁵

17
- 0010276632
- Lipid-DNA complexes induce potent activation of innate immune responses and antitumor activity when administered intravenously
- (1999) J Immunol , vol.163 , pp. 1552-1561
- Dow, S.W.¹ Fradkin, L.G.² Uggitt, D.H.³ Willson, A.P.⁴ Heath, T.D.⁵ Potter, T.A.⁶

18
- 0033544946
- Intravenous cytokine gene delivery by lipid-DNA complexes controls the growth of established lung metastases
- (1999) Hum Gene Ther , vol.10 , pp. 2961-2972
- Dow, S.W.¹ Elmslie, R.E.² Fradkin, L.G.³ Liggitt, D.H.⁴ Heath, T.D.⁵ Willson, A.P.⁶ Potter, T.A.⁷

19
- 0032929423
- Gene therapy - Phase I trial for primary untreated head and neck squamous cell cancer (HNSCC) UICC stage II-IV with a single intratumoral injection of hIL-2 plasmids formulated in DOTMA/Chol
- (1999) Hum Gene Ther , vol.10 , pp. 141-147
- Wollenberg, B.¹ Kastenbauer, D.² Mundl, H.³ Schaumberg, J.⁴ Mayer, A.⁵ Andratschke, M.⁶ Lang, S.⁷ Pauli, C.⁸ Zeidler, R.⁹ Ihrier, S.¹⁰ Lohrs, U.¹¹ Naujoks, K.¹² Rollston, R.¹³

20
- 0033586318
- Intratracheal administration of interleukin-12 plasmid-cationic lipid complexes inhibits murine lung metastases
- (1999) Hum Gene Ther , vol.10 , pp. 723-731
- Blezinger, P.¹ Freimark, B.D.² Matar, M.³ Wilson, E.⁴ Singhal, A.⁵ Min, W.⁶ Nordstrom, J.L.⁷ Pericle, F.⁸

21
- 0032886544
- Immunotherapy of advanced malignancy by direct gene transfer of an interleukin-2 DNA/DMRIE/DOPE lipid complex: Phase I/II experience
- (1999) J Clin Oncol , vol.17 , pp. 3313-3323
- Galanis, E.¹ Hersh, E.M.² Stopeck, A.T.³ Gonzalez, R.⁴ Burch, P.⁵ Spier, C.⁶ Akporiaye, E.T.⁷ Rinehart, J.J.⁸ Edmonson, J.⁹ Sobol, R.E.¹⁰ Forscher, C.¹¹ Sondak, V.K.¹² Lewis, B.D.¹³ Unger, E.C.¹⁴ O'Driscoll, M.¹⁵ Selk, L.¹⁶ Rubin, J.¹⁷

22
- 0033052989
- Intratumoral delivery of IL-12 gene by polyvinyl polymeric vector system to murine renal and colon carcinoma results in potent antitumor immunity
- (1999) Gene Ther , vol.6 , pp. 833-839
- Mendiratta, S.K.¹ Quezada, A.² Matar, M.³ Wang, J.⁴ Hebel, H.L.⁵ Long, S.⁶ Nordstrom, J.L.⁷ Pericle, F.⁸

23
- 0032982624
- Synergistic effect of formulated plasmid and needle-free injection for genetic vaccines
- (1999) Pharm Res , vol.16 , pp. 889-895
- Anwer, K.¹ Earle, K.A.² Shi, M.³ Wang, J.⁴ Mumper, R.J.⁵ Proctor, B.⁶ Jansa, K.⁷ Ledebur, H.C.⁸ Davis, S.⁹ Eaglstein, W.¹⁰ Rolland, A.P.¹¹

24
- 0033542389
- Ligand-dependent regulation of plasmid-based transgene expression in vivo
- (1999) Hum Gene Ther , vol.10 , pp. 1499-1507
- Abruzzese, R.V.¹ Godin, D.² Burcin, M.³ Mehta, V.⁴ French, M.⁵ Li, Y.⁶ O'Malley, B.W.⁷ Nordstrom, J.L.⁸

25
- 0032892179
- Systemic inhibition of tumor growth and tumor metastases by intramuscular administration of the endostatin gene
- (1999) Nature Biotechnol , vol.17 , pp. 343-348
- Blezinger, P.¹ Wang, J.² Gondo, M.³ Quezada, A.⁴ Mehrens, D.⁵ French, M.⁶ Singhal, A.⁷ Sullivan, S.⁸ Rolland, A.⁹ Ralston, R.¹⁰ Min, W.¹¹

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.