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Volumn 6, Issue 5, 1999, Pages 833-839

Intratumoral delivery of IL-12 gene by polyvinyl polymeric vector system to murine renal and colon carcinoma results in potent antitumor immunity

Author keywords

Cancer; Gene delivery; Gene therapy; IL 12; Immunotherapy

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 12; POLYVINYL DERIVATIVE;

EID: 0033052989     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300891     Document Type: Article
Times cited : (73)

References (37)
  • 1
    • 0027133645 scopus 로고
    • Mechanisms of action and toxicity of immunotherapy with cytokines
    • Mier JW, Atkins MB. Mechanisms of action and toxicity of immunotherapy with cytokines. Curr Op Oncol 1993; 5: 1067-1072.
    • (1993) Curr Op Oncol , vol.5 , pp. 1067-1072
    • Mier, J.W.1    Atkins, M.B.2
  • 2
    • 0028987902 scopus 로고
    • Role of interferon-γ in mediating the antitumor efficacy of interleukin-12
    • Brunda MJ et al. Role of interferon-γ in mediating the antitumor efficacy of interleukin-12. J Immunother 1995; 17: 71-77.
    • (1995) J Immunother , vol.17 , pp. 71-77
    • Brunda, M.J.1
  • 3
    • 0027963161 scopus 로고
    • Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production
    • Nastala CL et al. Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production. J Immunol 1994; 153: 1697-1706.
    • (1994) J Immunol , vol.153 , pp. 1697-1706
    • Nastala, C.L.1
  • 4
    • 0030879639 scopus 로고    scopus 로고
    • Cytokine gene therapy of cancer using gene gun technology: Superior antitumor activity of interleukin-12
    • Rakhmilevich AL et al. Cytokine gene therapy of cancer using gene gun technology: superior antitumor activity of interleukin-12. Hum Gene Ther 1997; 8: 1303-1311.
    • (1997) Hum Gene Ther , vol.8 , pp. 1303-1311
    • Rakhmilevich, A.L.1
  • 5
    • 0030739621 scopus 로고    scopus 로고
    • Antitumor efficacy of adenocarcicoma cells engineered to produce interleukin 12 (IL-12) or other cytokines compared with exogenous IL-12
    • Cavallo F et al. Antitumor efficacy of adenocarcicoma cells engineered to produce interleukin 12 (IL-12) or other cytokines compared with exogenous IL-12. J Natl Cancer Inst 1997; 89: 1049-1058.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1049-1058
    • Cavallo, F.1
  • 6
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immuno-regularory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri G. Interleukin-12: a proinflammatory cytokine with immuno-regularory functions that bridge innate resistance and antigen-specific adaptive immunity. Ann Rev Immunol 1995; 13: 251-276.
    • (1995) Ann Rev Immunol , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 7
    • 0025873502 scopus 로고
    • Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor)
    • Gately MK et al. Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor). J Immunol 1991; 147: 874-882.
    • (1991) J Immunol , vol.147 , pp. 874-882
    • Gately, M.K.1
  • 8
    • 0026441372 scopus 로고
    • Natural killer (NK) cell stimulatory factor or IL-12 has differential effects on the proliferation of TCR-αβ+, TCR-γδ+ T lymphocytes and NK cells
    • Perussia B et al. Natural killer (NK) cell stimulatory factor or IL-12 has differential effects on the proliferation of TCR-αβ+, TCR-γδ+ T lymphocytes and NK cells. J Immunol 1992; 149: 3495-3502.
    • (1992) J Immunol , vol.149 , pp. 3495-3502
    • Perussia, B.1
  • 9
    • 0026520178 scopus 로고
    • Response of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): Cytolytic activity and proliferation of NK cells are differentially regulated by NKSF
    • Robertson MJ et al. Response of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): cytolytic activity and proliferation of NK cells are differentially regulated by NKSF. J Exp Med 1992; 175: 779-788.
    • (1992) J Exp Med , vol.175 , pp. 779-788
    • Robertson, M.J.1
  • 10
    • 0024467154 scopus 로고
    • Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
    • Kobayashi M et al. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J Exp Med 1989; 170: 827-845.
    • (1989) J Exp Med , vol.170 , pp. 827-845
    • Kobayashi, M.1
  • 11
    • 0026532085 scopus 로고
    • Comparative study of IL-12 (cytotoxic lymphocyte maturation factor)-, IL-2, and IL-7-induced effects on immunomagnetically purified CD56+ NK cells
    • Naume B, Gately MK, Espevik TA. Comparative study of IL-12 (cytotoxic lymphocyte maturation factor)-, IL-2, and IL-7-induced effects on immunomagnetically purified CD56+ NK cells. J Immunol 1992; 148: 2429-2436.
    • (1992) J Immunol , vol.148 , pp. 2429-2436
    • Naume, B.1    Gately, M.K.2    Espevik, T.A.3
  • 12
    • 0026691714 scopus 로고
    • Regulation of human cytolytic lymphocyte responses by interleukin-12
    • Gately MK, Wolitzky AG, Quinn PM, Chizzonite R. Regulation of human cytolytic lymphocyte responses by interleukin-12. Cell Immunol 1992; 143: 127-142.
    • (1992) Cell Immunol , vol.143 , pp. 127-142
    • Gately, M.K.1    Wolitzky, A.G.2    Quinn, P.M.3    Chizzonite, R.4
  • 13
    • 0025819340 scopus 로고
    • Induction of interferon gamma production by natural killer cell stimulatory factor: Characterization of the responder cells and synergy with other inducers
    • Chan SH et al. Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers. J Exp Med 1991; 173:869-879.
    • (1991) J Exp Med , vol.173 , pp. 869-879
    • Chan, S.H.1
  • 14
    • 0027239503 scopus 로고
    • Antitumor and antimetastatic activity of interleukin 12 against murine tumors
    • Brunda MJ et al. Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J Exp Med 1994; 178: 1223-1230.
    • (1994) J Exp Med , vol.178 , pp. 1223-1230
    • Brunda, M.J.1
  • 15
    • 0030070446 scopus 로고    scopus 로고
    • Cytokine and chemokine expression in tumors of mice receiving systemic therapy with IL-12
    • Tannenbaum CS et al. Cytokine and chemokine expression in tumors of mice receiving systemic therapy with IL-12. J Immunol 1996; 156: 693-699.
    • (1996) J Immunol , vol.156 , pp. 693-699
    • Tannenbaum, C.S.1
  • 16
    • 0029031790 scopus 로고
    • Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo
    • Angiolillo AL et al. Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo. J Exp Med 1995; 182: 155-162.
    • (1995) J Exp Med , vol.182 , pp. 155-162
    • Angiolillo, A.L.1
  • 17
    • 0027336689 scopus 로고
    • Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages
    • Hsieh CS et al. Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science 1993; 260: 547-549.
    • (1993) Science , vol.260 , pp. 547-549
    • Hsieh, C.S.1
  • 18
    • 0027409793 scopus 로고
    • Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type (Th1)-specific immune responses and inhibits the development of IL-4 producing Th cells
    • Manetti R et al. Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type (Th1)-specific immune responses and inhibits the development of IL-4 producing Th cells. J Exp Med 1993; 177: 1199-1204.
    • (1993) J Exp Med , vol.177 , pp. 1199-1204
    • Manetti, R.1
  • 19
    • 0028957492 scopus 로고
    • Mechanism of interleukin 12-mediated toxicities during experimental viral infections: Role of tumor necrosis factor and glucocorticoids
    • Orange JS et al. Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids. J Exp Med 1995; 181: 901-914.
    • (1995) J Exp Med , vol.181 , pp. 901-914
    • Orange, J.S.1
  • 20
    • 0000824394 scopus 로고
    • Cancer trial of interleukin-12 halted
    • Marshall E. Cancer trial of interleukin-12 halted. Science 1995; 268: 1555.
    • (1995) Science , vol.268 , pp. 1555
    • Marshall, E.1
  • 21
    • 0029148905 scopus 로고
    • Cancer immunotherapy of established tumors with IL-12: Effective delivery by genetically engineered fibroblasts
    • Zitvogel L et al. Cancer immunotherapy of established tumors with IL-12: effective delivery by genetically engineered fibroblasts. J Immunol 1995; 155: 1393-1403.
    • (1995) J Immunol , vol.155 , pp. 1393-1403
    • Zitvogel, L.1
  • 22
    • 0027953555 scopus 로고
    • Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo
    • Tahara H et al. Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo. Cancer Res 1994; 54: 182-189.
    • (1994) Cancer Res , vol.54 , pp. 182-189
    • Tahara, H.1
  • 23
    • 0029053343 scopus 로고
    • Effective eradication of established murine tumors with IL-12 gene therapy using a polycistronic retroviral vector
    • Tahara H et al. Effective eradication of established murine tumors with IL-12 gene therapy using a polycistronic retroviral vector. J Immunol 1995; 154: 6466-6474.
    • (1995) J Immunol , vol.154 , pp. 6466-6474
    • Tahara, H.1
  • 24
    • 0028625325 scopus 로고
    • Construction and characterization of retroviral vectors expressing biologically active human interleukin-12
    • Zitvogel L et al. Construction and characterization of retroviral vectors expressing biologically active human interleukin-12. Hum Gene Ther 1994; 5: 1493-1506.
    • (1994) Hum Gene Ther , vol.5 , pp. 1493-1506
    • Zitvogel, L.1
  • 25
    • 0028840525 scopus 로고
    • High cytokine production and effective antitumor activity of a recombinant vaccinia virus encoding murine interleukin 12
    • Meko JB, Yim JH, Tsung K, Norton JA. High cytokine production and effective antitumor activity of a recombinant vaccinia virus encoding murine interleukin 12. Cancer Res 1995; 55: 4765-4770.
    • (1995) Cancer Res , vol.55 , pp. 4765-4770
    • Meko, J.B.1    Yim, J.H.2    Tsung, K.3    Norton, J.A.4
  • 26
    • 0029848051 scopus 로고    scopus 로고
    • Direct intratumoral injection of an adenovirus expressing interleukin-12 induces regression and long-lasting immunity that is associated with highly localized expression of interleukin-12
    • Bramson JL et al. Direct intratumoral injection of an adenovirus expressing interleukin-12 induces regression and long-lasting immunity that is associated with highly localized expression of interleukin-12. Hum Gene Ther 1996; 7: 1995-2002.
    • (1996) Hum Gene Ther , vol.7 , pp. 1995-2002
    • Bramson, J.L.1
  • 27
    • 0029891916 scopus 로고    scopus 로고
    • Polyvinyl derivatives as novel interactive polymers controlled gene delivery to muscle
    • Mumper RJ et al. Polyvinyl derivatives as novel interactive polymers controlled gene delivery to muscle. Pharmac Res 1996; 5: 701-709.
    • (1996) Pharmac Res , vol.5 , pp. 701-709
    • Mumper, R.J.1
  • 28
    • 0030726175 scopus 로고    scopus 로고
    • Expression of biologically active human insulin-like growth factor-I following intramuscular injection of a formulated plasmid in rats
    • Alila H et al. Expression of biologically active human insulin-like growth factor-I following intramuscular injection of a formulated plasmid in rats. Hum Gene Ther 1997; 8: 1785-1795.
    • (1997) Hum Gene Ther , vol.8 , pp. 1785-1795
    • Alila, H.1
  • 29
    • 2642690755 scopus 로고    scopus 로고
    • Systemic effect of human growth hormone after intramuscular injection of a single dose of a muscle-specific gene medicine
    • Anwer K et al. Systemic effect of human growth hormone after intramuscular injection of a single dose of a muscle-specific gene medicine. Hum Gene Ther 1998; 9: 659-670.
    • (1998) Hum Gene Ther , vol.9 , pp. 659-670
    • Anwer, K.1
  • 30
    • 0022992144 scopus 로고
    • Interferon and major histocompatibility complex genes: A model to analyse eukaryotic gene regulation?
    • Rosa FM, Cochet MM, Fellous M. Interferon and major histocompatibility complex genes: a model to analyse eukaryotic gene regulation? Interferon 1986; 7: 48-87.
    • (1986) Interferon , vol.7 , pp. 48-87
    • Rosa, F.M.1    Cochet, M.M.2    Fellous, M.3
  • 31
    • 0028968497 scopus 로고
    • Administration of recombinant interleukin-12 to mice suppresses hematopoiesis in the bone marrow but enhances hematopoiesis in the spleen
    • Tare NS, et al. Administration of recombinant interleukin-12 to mice suppresses hematopoiesis in the bone marrow but enhances hematopoiesis in the spleen. J Interfer Cytok Res 1995; 15: 377-383.
    • (1995) J Interfer Cytok Res , vol.15 , pp. 377-383
    • Tare, N.S.1
  • 32
    • 0029814589 scopus 로고    scopus 로고
    • Antitumor and antimetastatic effects of interleukin 12
    • Fujiwara H, Hamoaka T. Antitumor and antimetastatic effects of interleukin 12. Cancer Chemother Pharmacol 1996; 38 (Suppl.): S22-S26.
    • (1996) Cancer Chemother Pharmacol , vol.38 , Issue.SUPPL.
    • Fujiwara, H.1    Hamoaka, T.2
  • 33
    • 0032482337 scopus 로고    scopus 로고
    • A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell
    • Ridge JP, Rosa FD, Matzinger P. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell. Nature 1998; 393: 474-478.
    • (1998) Nature , vol.393 , pp. 474-478
    • Ridge, J.P.1    Rosa, F.D.2    Matzinger, P.3
  • 34
    • 0032080647 scopus 로고    scopus 로고
    • Cationic lipids enhance cytokine and cell influx levels in the lung following administration of plasmid: Cationic lipid complexes
    • Freimark BD et al. Cationic lipids enhance cytokine and cell influx levels in the lung following administration of plasmid: cationic lipid complexes. J Immunol 1998; 160: 4580-4586.
    • (1998) J Immunol , vol.160 , pp. 4580-4586
    • Freimark, B.D.1
  • 35
    • 0028928622 scopus 로고
    • CD4 T cells inhibit in vivo the CD8-mediated immune response against murine colon carcinoma cells transduced with interleukin-12 genes
    • Martinotti A et al. CD4 T cells inhibit in vivo the CD8-mediated immune response against murine colon carcinoma cells transduced with interleukin-12 genes. Eur J Immunol 1995; 25: 137-146.
    • (1995) Eur J Immunol , vol.25 , pp. 137-146
    • Martinotti, A.1
  • 36
    • 0029898839 scopus 로고    scopus 로고
    • Amount of interleukin 12 available at the tumor site is critical for tumor regression
    • Colombo MP et al. Amount of interleukin 12 available at the tumor site is critical for tumor regression. Cancer Res 1996; 56: 2531-2534.
    • (1996) Cancer Res , vol.56 , pp. 2531-2534
    • Colombo, M.P.1
  • 37
    • 0033586318 scopus 로고    scopus 로고
    • Intra-tracheal administration of IL-12 plasmid/cationic lipid complexes inhibits murine lung metastases
    • in press
    • Blezinger P et al. Intra-tracheal administration of IL-12 plasmid/cationic lipid complexes inhibits murine lung metastases. Hum Gene Ther (in press).
    • Hum Gene Ther
    • Blezinger, P.1


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