Cationic phosphonolipids as nonviral gene transfer agents in the lungs of mice

Human Gene Therapy

Volumn 9, Issue 16, 1998, Pages 2309-2319

  Guillaume Gable, Christine ^a   Floch, Virginie ^a   Mercier, Bernard ^a   Audrézet, Marie Pierre ^a   Gobin, Eric ^c   Le Bolc'h, Gwenaëlle ^b   Yaouanc, Jean Jacques ^b   Clément, Jean Claude ^b   Des Abbayes, Hervé ^b   Leroy, Jean Paul ^c   Morin, Vincent ^d   Férec, Claude ^a,e  

^a UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

^b Centre National de la Recherche Scientifique   (France)

^c CHU MORVAN   (France)

^d FACULTÉ DE MÉDECINE ET DES SCIENCES DE LA SANTÉ   (France)

^e ETSBO   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CATION; LIPID;

ANIMAL TISSUE; ARTICLE; CELL LINE; CHEMOLUMINESCENCE; CONTROLLED STUDY; CYSTIC FIBROSIS; CYTOFLUOROMETRY; DNA TRANSFECTION; GENE TARGETING; GENE TRANSFER; LUNG; LUNG ALVEOLUS EPITHELIUM; MOUSE; NONHUMAN; REPORTER GENE;

EID: 17344362631     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1998.9.16-2309     Document Type: Article

References (8)

1. ABERLE, A., BENNETT, M., MALONE, R., and NANTZ, M. (1996). The counterion influence on cationic lipid-mediated transfection of plasmid DNA. Biochim. Biophys. Acta 1299, 281-283.
2. ALTON, E.W., MIDDLETON, P.G., CAPLEN, N.J., SMITH, S.N., STEEL, D.M., MUNKONGE, F.M., JEFFERY, P.K., GEDDES, D.M., HART, S.L., and WILLIAMSON, R. (1993). Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice. Nature Genet. 5, 135-142.
3. AUDREZET, M.P., LE BOLC'H, G., FLOCH, V., YAOUANC, J.J., CLEMENT, J.C., DES ABBAYES, H., MERCIER, B., PAUL, A., and FEREC, C. (1997). Novel cationic phosphonolipids agents for in vitro gene transfer to epithelial cell lines. J. Liposome Res. 7, 273-300.
4. BALASUBRAMANIAM, R.P., BENNETT, M., ABERLE, A., MALONE, J., NANTZ, M., and MALONE, R. (1996). Structural and functional analysis of cationic transfection lipids: The hydrophobic domain. Gene Ther. 3, 163-172.
5. BELLON, G., MICHEL-CALEMARD, L., THOUVENOT, D., JAGNEAUX, V., POITEVIN, F., MALCUS, C., ACCART, N., LAYANI, M.P., AYMARD, M., BERNON, H., BIENVENU, J., COURTNEY, M., DURING, G., GILLY, B., GILLY, R., LAMY, D., LEVREY, H., MOREL, Y., PAULIN, C., PERRAUD, F., RODILLON, L., SENE, C., SATTA, S., TOURAINE-MOULIN, F., SCHATZ, C., and PAVARINI, A. (1997). Aerosol administration of a recombinant adenovirus expressing CFTR to cystic fibrosis patients: A phase I clinical trial. Hum. Gene Ther. 8, 15-25.
6. BOAT, T., WELSH, M.J., and BEAUDET, A.L. (1989). Cystic fibrosis. The metabolic basis of inherited disease. C.R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, eds. (MacGraw-Hill, Inc., New York, NY) pp. 2649-2680.
7. BOUSSIF, O., ZANTA, M.A., and BEHR, J.P. (1996). Optimised galenics improve in vitro gene transfer with cationic molecules up to 1000-fold. Gene Ther. 3, 1074-1080.
8. CAPLEN, N.J., ALTON, E.W.F.W., MIDDLETON, P.G., DORIN, J.R., STEVENSON, B.J., GAO, X., DURHAM, S.R., JEFFERY, P.K., HUDSON, M.E., COUTELLE, C., HUANG, L., PORTEOUS, D.J., WILLIAMSON, R., and GEDDES, D.M. (1995). Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nature Med. 1, 39-46.