Genetic analysis for common complex disease

American Heart Journal

Volumn 140, Issue 4, 2000, Pages

  Hauser, E R ^a   Pericak Vance, M A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E;

CONFERENCE PAPER; CORONARY ARTERY DISEASE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC DISORDER; GENETIC EPIDEMIOLOGY; GENETIC LINKAGE; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; PRIORITY JOURNAL;

EID: 0033814545     PISSN: 00028703     EISSN: None     Source Type: Journal    
DOI: 10.1067/mhj.2000.108946     Document Type: Conference Paper

References (78)

1. Genetic dissection of complex traits
2. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
3. Detection of deletions spanning the Duchenne muscular dystrophy focus using a tightly linked DNA segment
4. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease
5. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
6. Linkage disequilibrium mapping of complex disease: Fantasy or reality?
7. Automated construction of genetic linkage maps using an expert system (MultiMap): A human genome linkage map
8. A comprehensive human linkage map with centimorgan density. Cooperative Human Linkage Center (CHLC)
9. Comprehensive human genetic maps: Individuals and sex-specific variation in recombination
10. Genomics: Drug firms to create public database of genetic mutations
11. Linkage studies in familial Alzheimer's disease: Evidence for chromosome 19 linkage
12. Analysis of association at SNPs in the APOE region
13. Sequential tests for the detection of linkage
14. The detection of autosomal linkage in data which consists of pairs of brothers and sisters of unspecified parentage
15. Linkage strategies for genetically complex traits I. Multilocus models
16. Linkage strategies for genetically complex traits II. The power of affected relative pairs
17. Linkage strategies for genetically complex traits III. The effect of marker polymorphism on analysis of affected pairs
18. Complete multipoint sib-pair analysis of qualitative and quantitative traits
19. Affected-sib-pair interval mapping and exclusion for complex genetic traits - Sampling considerations
20. Genetic linkage analysis of complex genetic traits by using affected sibling pairs
21. Allele-sharing models: LOD scores and accurate linkage tests
22. Loci on chromosome 2 (NIDDM 1) and 15 interact to increase susceptibility to diabetes in Mexican Americans
23. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
24. Human pedigree-based quantitative-trait-locus mapping: Localization of two genes influencing HDL cholesterol metabolism
25. Lipoprotein(a)-cholesterol and coronary heart disease in The Framingham Heart Study
26. Mapping genes for noninsulin dependent diabetes mellitus: Design of the Finland-United States investigation of NIDDM genetics (FUSION) study
27. Allegmeine Zeitschrift fur Psychiatrie
28. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
29. Candidate gene for the chromosome 1 familial Alzheimer's disease locus
30. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
31. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
32. Genetic linkage studies in Alzheimer's disease families
33. Familial aggregation in Alzheimer's disease: Comparison of risk among first degree relatives of early- and late-onset cases, and among male and female relatives in a successive generation
34. Genetic studies on an Alzheimer clinic population
35. Familial risks for Alzheimer disease: Data from an Alzheimer clinic population
36. Apolipoprotein E polymorphism and coronary artery disease
37. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and cru plaque amyloid in Creutzfeldt-Jakob disease
38. Apolipoprotein E: A pathological chaperone protein in patients with cerebral and systemic amyloid
39. Association of apolipoprotein E allele ε4 with late-onset familial and sporadic Alzheimer's disease
40. Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
41. ApoE-epsilon 4 and early-onset Alzheimer's disease
42. Apolipoprotein E e4 allele in a population-based study of early-onset Alzheimer's disease
43. Alzheimer's disease and other dementias
44. Protective effect of apoliprotein e type 2 allele for late onset Alzheimer disease
45. APOE and Alzheimer's disease: Examination of allelic association and effect on age at onset in both early- and late-onset cases
46. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium
47. The apolipoprotein E2 allele is associated with an increased risk of early-onset Alzheimer's disease and a reduced survival
48. ApoE allele frequencies in Italian sporadic and familial Alzheimer's disease
49. Apolipoprotein E ε2 does not increase risk of early-onset sporadic Alzheimer disease
50. Heredity in dementia of the Alzheimer type
51. Relative risk of Alzheimer disease and age-at-onset distributions, based on APOE genotypes among elderly African Americans, Caucasians, and Hispanics in New York City
52. Apolipoprotein E and Alzheimer's disease: Ethnic variation in genotypic risks
53. Familial dementia studies in an Amish population
54. Apolipoprotein E E4 allele and risk of dementia
55. The number of trait loci in late-onset Alzheimer disease
56. A full genome scan for late onset Alzheimer's disease
57. Complete genomic screen in late-onset familial Alzheimer disease: Evidence for a new locus on chromosome 12
58. Linkage evidence supports the involvement of chromosome 15 in autistic disorder (AUT)
59. Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity
60. Genetic studies an chromosome 12 in late-onset Alzheimer disease
61. Genetic association studies between dementia of the Alzheimer's type and three receptors for apolipoprotein E in a Caucasian population
62. Alpha-2 macroglobulin is genetically associated with Alzheimer disease
63. No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease
64. An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease
65. Alpha-2 macroglobulin polymorphism and Alzheimer disease risk in the UK
66. Alpha-2 macroglobulin gene and Alzheimer disease
67. APOE* 4-associated Alzheimer's disease risk is modified by alpha 1-antichymotrypsin polymorphism
68. Genetic association between an intronic polymorphism in the presenilin 1 gene and late onset Alzheimer's disease
69. Frameshift mutants of beta amyloid precursor protein and ubiquitin-b in Alzheimers and Down patients
70. Evidence for association of HLA-A2 allele with onset age of Alzheimer's disease
71. HLA-DR antigens associated with major genetic risk for late-onset Alzheimer's disease
72. Synergy between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset confirmed Alzheimer's disease
73. Genetic studies in Alzheimer's disease with an NACP/alpha-synuclein polymorphism
74. A mitochondrial DNA clone s associated with increased risk for Alzheimer disease