Mitogen-activated protein (MAP) kinase pathways in plants: Versatile signaling tools

International Review of Cytology

Volumn 201, Issue , 2001, Pages 209-275

  Ligterink, Wilco ^a   Hirt, Heribert ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

Cell cycle; Hormones; MAP kinase; Phosphorylation; Protein kinase; Signal transduction; Stress

Indexed keywords

GIBBERELLIN; MITOGEN ACTIVATED PROTEIN KINASE;

AMINO ACID SEQUENCE; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME ISOLATION; ENZYME MECHANISM; NONHUMAN; PHOSPHORYLATION; PHYLOGENY; PHYTOCHEMISTRY; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

CELL CYCLE; EUKARYOTIC CELLS; GENE EXPRESSION REGULATION, PLANT; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; PHYLOGENY; PLANT DISEASES; PLANT GROWTH REGULATORS; PLANTS; PROTEIN STRUCTURE, TERTIARY; WOUND HEALING;

EUKARYOTA; MAMMALIA;

EID: 0033780929     PISSN: 00747696     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0074-7696(01)01004-X     Document Type: Article

References (327)

1. Extracellular signal-regulated kinase 7 (ERK7), a novel ERK with a C-terminal domain that regulates its activity, its cellular localization, and cell growth
2. Early genes and auxin action
3. Rapid and transient activation of a myelin basic protein kinase in tobacco leaves treated with harpin from Erwinia amylovora
4. Metabolic labeling of mitogen-activated protein kinase kinase in A431 cells demonstrates phosphorylation on serine and threonine residues
5. Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein microtubule-associated protein 2 kinase
6. Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines
7. Identification of the sites in MAP kinase kinase-1 phosphorylated by p74(raf-1)
8. Isolation of a wheat cDNA clone for an abscisic acid inducible transcript with homology to protein kinases
9. NPK1, a tobacco gene that encodes a protein with a domain homologous to yeast BCK1, STE11, and Byr2 protein kinases
10. Isolation and characterization of cDNA clones that encode protein kinases of Nicotiana tabacum
11. A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs
12. Evidence suggesting protein tyrosine phosphorylation in plants depends on the developmental conditions
13. Receptor kinases in plant development
14. Polypeptide signaling for plant defensive genes exhibits analogies to defense signaling in animals
15. Gibberellin signaling
16. GTP-binding proteins in plants
17. Early signal transduction pathways in plant-pathogen interactions
18. A MAP kinase is activated late in plant mitosis and becomes localized to the plane of cell division
19. Wounding induces the rapid and transient activation of a specific MAP kinase pathway
20. Mechanosensors in plants
21. Genetic analysis of ABA signal transduction pathways
22. An insulin-stimulated protein kinase similar to yeast kinases involved in cell-cycle control
23. Local and systemic signals in the wound response
24. Rain-, wind-, and touch-induced expression of calmodulin and calmodulin-related genes in Arabidopsis
25. The dual-specificity mitogen-activated protein kinase phosphatase-1 and -2 are induced by the p42/p44(MAPK) cascade
26. Why do protein kinase cascades have more than one level?
27. Two distinct Raf domains mediate interaction with Ras
28. Identification of MAP kinase domains by redirecting stress signals into growth factor responses
29. Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth-factor-induced gene expression and cell-cycle entry
30. Growth-factor-stimulated MAP kinase induces rapid retrophosphorylation and inhibition of MAP kinase kinase (MEK1)
31. Calcium regulation in plant cells and its role in signaling
32. Order of action of components in the yeast pheromone response pathway revealed with a dominant allele of the STE11 kinase and the multiple phosphorylation of the STE7 kinase
33. A cell-cycle-regulated MAP kinase with a possible role in cytokinesis in tobacco cells
34. Activation mechanism of the MAP kinase ERK2 by dual phosphorylation
35. The regulation of anoikis: MEKK-1 activation requires cleavage by caspases
36. A proline-rich sequence unique to MEK1 and MEK2 is required for Raf binding and regulates MEK function
37. Regulation of p42 mitogen-activated protein kinase activity by protein phosphatase 2A under conditions of growth inhibition by epidermal growth factor in A431 cells
38. Role of phosphorylation in elicitation of the oxidative burst in cultured soybean cells
39. Activation of phospholipase A by plant defense elicitors
40. The two-component system. Regulation of diverse signaling pathways in prokaryotes and eukaryotes
41. Activation of the ethylene gas response pathway in Arabidopsis by the nuclear protein ETHYLENE-INSENSITIVE3 and related proteins
42. Regulation of phosphorylation of chromatin-associated proteins in Lemna and Hordeum
43. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation - Duration of JNK activation may determine cell death and proliferation
44. Nuclear localization and regulation of erk- and rsk-encoded protein kinases
45. ERK3 is a constitutively nuclear protein kinase
46. Functional mapping of the N-terminal regulatory domain in the human Raf-1 protein kinase
47. Sequential phosphorylation by mitogen-activated protein kinase and glycogen synthase kinase-3 represses transcriptional activation by heat shock factor-1
48. Association of the Arabidopsis CTR1 Raf-like kinase with the ETR1 and ERS ethylene receptors
49. The CLAVATA1 gene encodes a putative receptor kinase that controls shoot and floral meristem size in Arabidopsis
50. A potential signaling role for profilin in pollen of Papaver rhoeas
51. Modular binding domains in signal transduction proteins
52. Protein dephosphorylation mediates salicylic acid induced expression of PR-1 genes in tobacco
53. Similar effects of platelet-derived growth factor and epidermal growth factor on the phosphorylation of tyrosine in cellular proteins
54. A putative protein kinase overcomes pheromone-induced arrest of cell cycling in Saceharomyces cerevisiae
55. Arabidopsis thaliana cDNA isolated by functional complementation shows homolgy to serine/threonine protein kinases
56. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
57. Oligosaccharins, brassinolides, and jasmonates: Nontraditional regulators of plant growth, development, and gene expression
58. The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product
59. Autoregulation of the Raf-1 serine/threonine kinase
60. The MEK1 proline-rich insert is required for efficient activation of the mitogen-activated protein kinases ERK1 and ERK2 in mammalian cells
61. Death don't have no mercy: Cell death programs in plant-microbe interactions
62. Regulation of the activity of MEK kinase 1 (MEKK1) by autophosphorylation within the kinase activation domain
63. A homologue of the MAP/ERK family of protein kinase genes is expressed in vegetative and in female reproductive organs of Petunia hybrida
64. Cell-cycle regulation during growth-dormancy cycles in pea axillary buds
65. Fungal elicitor triggers rapid, transient, and specific protein phosphorylation in parsley cell suspension cultures
66. MSG5, a novel protein phosphatase promotes adaptation to pheromone response is Saccharomyes cerevisiae
67. Rapid stimulation of a soybean protein-serine kinase that phosphorylates a novel bZIP DNA-binding protein, G/HBF-1, during the induction of early transcription-dependent defenses
68. MsERK1: A mitogen-activated protein kinase from a flowering plant
69. Serine/threonine protein phosphatase is required for tobacco-mosaio-virus-mediated programmed cell death
70. Salicylic acid and disease resistance in plants
71. Early events in the elicitation of plant defense
72. Glucose and stress independently regulate source and sink metabolism and defense mechanisms via signal transduction pathways involving protein phosphorylation
73. +/CDC28-related kinase required for the transition from mitosis into conjugation
74. Isolation of MEK5 and differential expression of alternatively spliced forms
75. MEKKs, GCKs, MLKs, PAKs, TAKs, and Tpls: Upstream regulators of the c-Jun amino-terminal kinases?
76. In vitro phosphorylation of plant plasma membrane proteins in response to the proteinase inhibitor inducing factor
77. 33P]phosphate
78. Rapid changes of protein phosphorylation are involved in transduction of the elicitor signal in plant cells
79. Cloning and characterization of a novel member of protein kinase family from soybean
80. How regulated protein translocation can produce switch-like responses
81. Tripping the switch fantastic: How a protein kinase cascade can convert graded inputs into switchlike outputs
82. Mechanistic studies of the dual phosphorylation of mitogen-activated protein kinase
83. The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes
84. Regulated nucleo cytoplasmic exchange of HOGI MAPK requires the importin β-homologues NMD5 and XPO1
85. Ethylene perception: From two-component signal transducers to gene induction
86. Higher plant tyrosine-specific protein phosphatases (PTPs) contain novel amino-terminal domains: Expression during embryogenesis
87. Interaction of MAP kinase with MAP kinase kinase: Its possible role in the control of nucleocytoplasmic transport of MAP kinase
88. Requirement of salicylic acid for the induction of systemic acquired resistance
89. Histidine kinase activity of the ETR1 ethylene receptor from Arabidopsis
90. De novo transcription of specific mRNAs during the induction of tobacco pollen embrygenesis
91. Organization and regulation of mitogen-activated protein kinase signaling pathways
92. Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1
93. Protein kinases
94. Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases
95. An abscisic acid induced protein kinase, PKABA1, mediates abscisic acid suppressed gene expression in barley aleurone layers
96. Identification of substrate recognition determinants for human ERK1 and ERK2 protein kinases
97. Xenopus M-phase MAP kinase: Isolation of its cDNA and activation by MPF
98. An endogenous factor of soybean (Glycin max L.) cell cultures activates phosphorylation of a protein which is dephosphorylated lated in vivo in elicitor-challenged cells
99. An insulin-stimulated ribosomal protein S6 kinase from rabbit liver
100. ABA signal transduction
101. K252a inhibits the response of tomato cells to fugal elicitors in vivo and their microsomal protein kinase in vitro
102. Identification of a dual-specificity protein phosphatase that inactivates a MAP kinase from Arabidopsis
103. Selective interaction of JNK protein kinase isoforms with transcription factors
104. MAP kinase pathways in the yeast Saccharomyces cerevisiae
105. The pathways connecting G-protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades
106. A tomato MAP kinase kinase gene (accession no. AJ000728) differentially regulated during fruit development, leaf senescence, and wounding
107. Molecular characterization and expression of an Arabidopsis thaliana L. MAP kinase kinase cDNA, AtMAP2Kα
108. Resistance-gene-dependent plant defense responses
109. Selective suppression of stress-activated protein kinase pathway by protein phosphatase 2C in mammalian cells
110. The eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification
111. The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
112. Molecular cloning and characterization of maize ZmMEK1, a protein kinase with a catalytic domain homologous to mitogen- and stress-activated protein kinase kinases
113. Tyrosine phosphatase signaling in a lower plant: Cell-cycle and oxidative-stress-regulated expression of the Chlamydomonas eugametos VH-PTP13gene
114. Insulin activates a novel adipocyte mitogen-activated protein kinase kinase kinase that shows rapid phasic kinetics and is distinct from c-Raf
115. Elicitation of plant hypersensitive response by bacteria
116. Hypersensitive response elicited by Erwinia amylovora harpin requires active plant metabolism
117. A heat-stress pulse inactivates a 50-kDa myelin basic protein kinase in tomato
118. Abscisic acid induced gene expression requires the activity of protein(s) sensitive to the protein-tyrosine phosphatase inhibitor phenylarsine oxide
119. MAP kinase pathways in yeast for mating and more
120. Abscisic acid signal transduction in epidermal cells of Pisum sativum L. Argenteum: Both dehydrin mRNA accumulation and stomatal responses require protein phosphorylation and dephosphorylation
121. Synthesis and phosphorylation of pollen proteins during the pollen-stigma interaction in self-compatible Brassica napus L. and self-incompatible Brassica oleracea L
122. Molecular genetics of auxin and cytokinin
123. Insulin stimulation of a MEK-dependent but ERK-independent SOS protein kinase
124. Gibberellins: Perception, transduction, and responses
125. An octadecanoid pathway mutant (JL5) of tomato is compromised in signaling for defense against insect attact
126. Is harpin-activated protein kinase related to salicylic acid- or fungal elicitor-induced kinases?
127. Ethylene responses are negatively regulated by a receptor gene family in Arabidopsis thaliana
128. Ultrasensitivity in the mitogen-activated protein kinase cascade
129. The protein kinases of budding yeast: Six score and more
130. Giberellin-regulated expression in oat aleurone cells of two kinases that show homology to MAP kinase and a ribosomal protein kinase
131. An Arabidopsis thaliana root-specific kinase homologue is induced by dehydration, ABA, and NaCl
132. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
133. Molecular cloning and characterization of three cDNAs encoding putative mitogen-activated protein kinase kinases (MAPKKs) in Arabidopsis thaliana
134. Isolation of ATMEKK1 (a MAPK kinase kinase kinase)-interacting proteins and analysis of a MAP kinase cascade in Arabidopsis
135. ATMRK1, an Arabidopsis protein kinase related to mammal mixed-lineage kinases and Raf protein kinases
136. 2 from the oxidative burst are essential components in triggering defense gene activation and phytoalexin synthesis in parsley
137. Structure-function studies of p38 mitogen-activated protein kinase. Loop 12 influences substrate specificity and autophosphorylation, but not upstream kinase selection
138. The ethylene gas signal transduction pathway: A molecular perspective
139. Stress signaling in plants: A MAP kinase pathway is activated by cold and drought
140. MMK2, a novel alfalfa MAP kinase, specifically complements the yeast MPK1 function
141. The plant homologue of MAP kinase is expressed in a cell-cycle-dependent and organ-specific manner
142. Heterotrimeric G-proteins are implicated in gibberellin induction of α-amylase gene expression in wild oat aleurone
143. Characterization of novel plant genes encoding MEKK/STE11 and RAF-related protein kinases
144. Plant MAP kinase kinase kinases' structure, classification, and evolution
145. Molecular cloning of an Arabidopsis thaliana MAP kinase related cDNA (accession no. Y07694)
146. Cytokinin signaling
147. CKI1, a histidine kinase homologue implicated in cytokinin signal transduction
148. The protein kinase C activated MAP kinase pathway of Saccharomyces cerevisiae mediates a novel aspect of the heat shock response
149. Inhibition by kinase inhibitors of the development and the disappearance of the preprophase band of microtubules in tobacco BY-2 cells
150. The five 'classical' plant hormones
151. Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase
152. Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation
153. CTR1, a negative regulator of the ethylene response pathway in Arabidopsis, encodes a member of the Raf family of protein kinases
154. Abscisic acid induces mitogen-activated protein kinase activation in barley aleurone protoplasts
155. Transgenic plant aequorin reports the effects of touch, cold shock, and elicitors on cytoplasmic calcium
156. Carbohydrate-modulated gene expression in plants
157. Suppression of auxin signal transduction by a MAPK cascade in higher plants
158. Phylogenetic and functional classification of mitogen-and stress-activated protein kinases
159. Okadaic acid, a protein phosphatase inhibitor, blocks calcium changes, gene expression, and cell death induced by gibberellin in wheat aleurone cells
160. Raf-1 activates MAP kinase kinase
161. Defective regulation of mitogen-activated protein kinase activity in a 3T3 cell variant mitogenically nonresponsive to tetradecanoyl phorbol acetate
162. A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
163. Challenges in understanding RLK function
164. Activation of MAPK homologues by elicitors in tobacco cells
165. Activation of the IκBα kinase complex by MEKK1, a kinase of the JNK pathway
166. Systemic elevation of phosphatidic acid and lysophospholipid levels in wounded plants
167. PRK1, a receptor-like kinase of Petunia inflata, is essential for postmeiotic development of pollen
168. Growth factors induce nuclear translocation of MAP kinases (p42(mapk) and p44(mapk)) but not of their activator MAP kinase kinase (p45(mapkk)) in fibroblasts
169. Molecular characterization of plant cDNAs BnMAP4Kα1 and BnMAP4Kα2 belonging to the GCK/SPS1 sub-family of MAP kinase kinase kinase kinase
170. Abscisic acid signal transduction
171. The Arabidopsis ABSCISIC ACID INSENSITIVE2 (ABI2) and ABI1 genes encode homologous protein phosphatases 2C involved in abscisic acid signal transduction
172. 2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response
173. An abscisic acid activated and calcium-independent protein kinase from guard cells of fava bean
174. MAP kinases in plant signal transduction: How many, what for?
175. Receptor-mediated activation of a MAP kinase in pathogen defense of plants
176. Inhibition of pollen tube elongation by microinjected anti-Rop 1Ps antibodies suggests a crucial role for Rho-type GTPases in the control of tip growth
177. A tomato sequence, TCTR2 (accession no. AJ005077), encoding an Arabidopsis CTR1 homologue
178. cPLA2 is phosphorylated and activated by MAP kinase
179. Transcription factors and their genes in higher plant's functional domains, evolution, and regulation
180. Protein phosphatases and signaling cascades in higher plants
181. MAPKKK-related protein kinase NPK1: Regulation of the M-phase of plant cell cycle
182. Protein phosphorylation inhibitors activate anti-fungal defense responses of soybean cotyledons and cell cultures
183. Kinetics of wound-induced hydraulic signals and variation potentials in wheat seedlings
184. Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
185. Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation
186. Cytoplasmic acidification as an early phosphorylation-dependent response of tobacco cells to elicitors
187. The plant wound hormone systemin binds with the N-terminal part to its receptor but needs the C-terminal part to activate it
188. MP2C, a plant protein phosphatase 2C, functions as a negative regulator of mitogen-activated protein kinase pathways in yeast and plants
189. The SAM kinase pathway: An integrated circuit for stress signaling in plants
190. Regulation of protein kinase cascades by protein phosphatase 2A
191. MAP kinase cascades in Arabidopsis: Their roles in stress and hormone responses
192. Identification of a possible MAP kinase cascade in Arabidopsis thaliana based on pairwise yeast two-hybrid analysis and functional complementation tests of yeast mutants
193. Environmental stress response in plants: The role of mitogen-activated protein kinases
194. A gene encoding a mitogen-activated protein kinase kinase kinase is induced simultaneously with genes for a mitogen-activated protein kinase and S6 ribosomal protein kinase by touch, cold, and water stress in Arabidopsis thaliana
195. Characterization of two cDNAs that encode MAP kinase homologues in Arabidopsis thaliana and analysis of the possible role of auxin in activating such kinase activities in cultured cells
196. ATMPKs: A gene family of plant MAP kinases in Arabidopsis thaliana
197. Low-temperature signal transduction during cold acclimation: Protein phosphatase 2A as an early target for cold inactivation
198. Cold-induced changes in freezing tolerance, protein phosphorylation, and gene expression - Evidence for a role of calcium
199. Abscisic acid activates a 48-kDa protein kinase in guard cell protoplasts
200. The pool of map kinase associated with microtubules is small but constitutively active
201. Cloning and characterization of MEK1, an Arabidopsis gene encoding a homologue of MAP kinase kinase
202. The complexity of Raf-1 regulation
203. Identification of the major phosphorylation sites of the Raf-1 kinase
204. 2, 4-Dichlorophenoxyacetic acid enhanced phosphorylation of soybean nuclear proteins
205. The expression pattern of the gene for NPK1 protein kinase related to mitogen-activated protein kinase kinase kinase (MAPKKK) in a tobacco plant: Correlation with cell proliferation
206. Heat-shock-induced activation of stress MAP kinase is regulated by threonine- and tyrosine-specific phosphatases
207. Possible involvement of differential splicing in regulation of the activity of Arabidopsis ANP1 that is related to mitogen-activated protein kinase kinase kinases (MAPKKKs)
208. The 'second-codon rule' and autophosphorylation govern the stability and activity of Mos during the meiotic cell cycle in Xenopus oocytes
209. High-affinity binding of a fungal oligopeptide elicitor to parsley plasma membranes triggers multiple defense responses
210. Phosphorylation of tobacco eukaryotic translation initiation factor 4A upon pollen tube germination
211. Mitogen-activated protein kinases p42(mapk) and p44(mapk) are required for fibroblast proliferation
212. Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase)
213. A polypeptide from tomato leaves induces wound-inducible proteinase inhibitor proteins
214. A higher plant seven-transmembrane receptor that influences sensitivity to cytokinins
215. Auxin-induced delay of abscission: The involvement of calcium ions and protein phosphorylation in bean plants
216. The Pisum sativum MAP kinase homologue (PsMAPK) rescues the Saccharomyces cerevisiae hog1 deletion mutant under conditions of high osmotic stress
217. Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro
218. Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: Scaffold role of Pbs2p MAPKK
219. Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 'two-component' osmosensor
220. Ultrastructural distribution of a MAP kinase and transcripts in quiescent and cycling plant cells and pollen grains
221. Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade
222. Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro
223. Ethylene signal is tranduced via protein phosphorylation events in plants
224. Auxin-regulated changes in protein phosphorylation in pea epicotyls
225. Association of mitogen-activated protein kinase with the microtubule cytoskeleton
226. Mitogen-activated protein kinase pathways
227. Contributions of the mitogen-activated protein (MAP) kinase backbone and phosphorylation loop to MEK specificity
228. Rapid Avr9- and Cf9-dependent activation of MAP kinases in tobacco cell cultures and leaves: Convergence of resistance gene, elicitor, wound, and salicylate responses
229. Ras, a versatile cellular switch
230. Mitogen-activated protein kinase kinase 1 (MKK1) is negatively regulated by threonine phosphorylation
231. Evidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase
232. Stress signaling in yeast
233. Systemic acquired resistance
234. Systemin: A polypeptide signal for plant defensive genes
235. Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: Potential involvement of an autocrine/paracrine mechanism
236. Immunological characterization of avian MAP kinases: Evidence for nuclear localization
237. Regulation by cytokinins of endogenous levels of jasmonic and salicylic acids in mechanically wounded tobacco plants
238. Expression of the gene for a small GTP-binding protein in transgenic tobacco elevates endogenous cytokinin levels, abnormally induces salicylic acid in response to wounding, and increases resistance to tobacco mosaic virus infection
239. MP1: A MEK-binding partner that enhances enzymatic activation of the MAP kinase cascade
240. Ethylene-binding sites generated in yeast expressing the Arabidopsis ETR1 gene
241. The alfalfa TDY1 gene encodes a MAP kinase homologue
242. 2+ and protein kinase activity
243. Sodium salicylate induces apoptosis via p38 mitogen-activated protein kinase but inhibits tumor necrosis factor induced c-Jun N-terminal kinase/stress-activated protein kinase activation
244. The MAPK signaling cascade
245. Purification and characterization of MAP kinase activator(s) from epidermal growth factor stimulated A431 cells
246. Jasmonic-based wound signal transduction requires activation of WIPK, a tobacco mitogen-activated protein kinase
247. Jasmonate acid in wound signal transduction pathways
248. Tobacco MAP kinase: A possible mediator in wound signal transduction pathways
249. PK12, a plant dual-specificity protein kinase of the LAMMER family, is regulated by the hormone ethylene
250. Activation of the MKK/ERK pathway during somatic cell mitosis: Direct interactions of active ERK with kinetochores and regulation of the mitotic 3F3/2 phosphoantigen
251. A tobacco protein kinase, NPK2, has a domain homologous to a domain found in activators of mitogen-activated protein kinases (MAPKKs)
252. Counteractive roles of protein phosphatase 2C (PP2C) and a MAP kinase kinase homologue in the osmoregulation of fission yeast
253. Gene expression and signal transduction in water-stress response
254. Molecular responses to drought and cold stress
255. Ethylene gas: Perception, signaling, and response
256. Pathogen defence in plants - A paradigm of biological complexity
257. Molecular cloning and expression of a MAP kinase homologue from pea
258. Phosphorylation of nuclear proteins directs binding to salicylic acid responsive elements
259. Myelin basic protein kinase activity in tomato leaves is induced systemically by wounding and increases in response to systemin and oligosaccharide elicitors
260. Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II
261. A functional homologue of mammalian protein kinase C participates in the elicitor-induced defense response in potato
262. The coordinated action of protein tyrosine phosphatases and kinases in cell signaling
263. MKP-1 (3CH134), an immediate early gene product, is a dual-specificity phosphatase that dephosphorylates MAP kinase in vivo
264. Transient activation and tyrosine phosphorylation of a protein kinase in tobacco cells treated with fungal elicitor
265. Slow and prolonged activation of the p47 protein kinase during hypersensitive cell death in a culture of tobacco cells
266. Studies on elicitor-signal transduction leading to differential expression of defense genes in cultured tobacco cells
267. Mastoparan induces an increase in cytosolic calcium ion concentration and subsequent activation of protein kinases in tobacco suspension culture cells
268. An increase in cytosolic calcium ion concentration precedes hypo-osmotic shock-induced activation of protein kinases in tobacco suspension culture cells
269. Protein phosphatase 2Cα inhibits the human stress-responsive p38 and JNK MAPK pathways
270. MAP kinase is required for the spindle assembly checkpoint but is dispensible for the normal M-phase entry and exit in Xenopus egg cell-cycle extracts
271. Biphasic activation of two mitogen-activated protein kinases during the cell cycle in mammalian cells
272. The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development
273. Three protein kinase structures define a common motif
274. Cytosolic acidification but not auxin at physiological concentrations is an activator of MAP kinase in tobacco cells
275. 2-terminal kinase kinases
276. Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor
277. An unusual protein kinase displaying characteristics of both the serine/threonine and tyrosine families is encoded by the Arabidopsis thaliana gene ATN1
278. Regulation of transcription by MAP kinase cascades
279. Mechanical signaling, calcium, and plant form
280. Phosphorylation of plant proteins and the identification of protein-tyrosine kinase activity in maize seedlings
281. The CLAVATA1 receptor-like kinase requires CLAVATA3 for its assembly into a signaling complex that includes KAPP and Rho-related protein
282. Feedback regulation of mitogen-activated protein kinase kinase kinase activity of c-Raf-1 by insulin and phorbol ester stimulation
283. Cutting activates a 46-kDa protein kinase in plants
284. Genetic analysis of protein tyrosine phosphatases
285. Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis
286. Protein phosphorylation is induced in tobacco cells by the elicitor cryptogein
287. Mammalian Ras interacts directly with the serine/threonine kinase Raf
288. Distinct steps in yeast spore morphogenesis require distinct SMK1 MAP kinase thresholds
289. A cDNA sequence isolated from the ripening tomato fruit encodes a putative protein kinase (accession no. Y13273)
290. The structure of mitogen-activated protein kinase p38 at 2.1-Å resolution
291. Apoptosis in barley aleurone during germination and its inhibition by abscisic acid
292. Jasmonate-signaled plant gene expression
293. Characterization of a serum-response-factor-like protein in Saccharomyces cerevisiae, R1m1, which has transcriptional activity regulated by the Mpk1 (Slt2) mitogen-activated protein kinase pathway
294. Insulin and epidermal growth factor receptors regulate distinct pools of Grb2-SOS in the control of Ras activation
295. Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals
296. Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways
297. Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human
298. Electrical signaling and systemic proteinase inhibitor induction in the wounded plant
299. An ethylene-inducible component of signal transduction encoded by never-ripe
300. Phosphorylation of MAP kinases by MAP/ERK involves multiple regions of MAP kinases
301. Evidence for the activation of a MAP kinase upon phosphate-induced cell-cycle reentry in tobacco cells
302. A developmentally regulated MAP kinase activated by hydration in tobacco pollen
303. Crystal structure of p38 mitogen-activated protein kinase
304. Molecular cloning, functional expression in Escherichia coli, and characterization of multiple mitogen-activated protein kinases from tobacco
305. Isolation and characterization of a tobacco cDNA clone encoding a putative MAP kinase
306. The timing of protein kinase activation events in the cascade that regulates mitotic progression in Tradescantia stamen hair cells
307. Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2
308. Two-component signal transducers and MAPK cascades
309. Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases
310. Crystal structure of JNK3: A kinase implicated in neuronal apoptosis
311. +-ATPase
312. MEKK1 binds directly to the c-Jun N-terminal kinases/stress-activated protein kinases
313. Molecular characterization of a tyrosine-specific protein phosphatase encoded by a stress-responsive gene in Arabidopsis
314. Signal perception and transduction in plant defense responses
315. Induction of hypersensitive cell death by a fungal protein in cultures of tobacco cells
316. Activation of 40-kDa protein kinases in response to hypo- and hypertonic shock in the halotolerant green alga Dunaliella tertioleca
317. Active MAP kinase in mitosis: Localization at kinetochores and association with the motor protein CENP-E
318. The tobacco wounding-actiyated mitogen-activated protein kinase is encoded by SIPK
319. Resistance gene N-mediated de novo synthesis and activation of a tobacco mitogen-activated protein kinase by tobacco mosaic virus infection
320. Salicylic acid activates a 48-kDa MAP kinase in tobacco
321. Activation of the tobacco SIP kinase by both a cell-wall-derived carbohydrate elicitor and purified proteinaceous elicitins from Phythophthora spp
322. Activity of the MAP kinase ERK2 is controlled by a flexible surface loop
323. Atomic structure of the MAP kinase ERK2 at 2.3-Å resolution
324. Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues
325. Components of a new human protein kinase signal transduction pathway
326. 2+-permeable ion channel involved in pathogen defense
327. MEK1 mediates a positive feedback on Raf-1 activity independently of Ras and Src