-
1
-
-
0029745382
-
Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: Binding and activation correlate with antidiabetic actions in db/db mice
-
(1996)
Endocrinology
, vol.137
, pp. 4189-4195
-
-
Berger, J.1
Bailey, P.2
Biswas, C.3
Cullinan, C.A.4
Doebber, T.W.5
Hayes, N.S.6
Saperstein, R.7
Smith, R.G.8
Leibowitz, M.D.9
-
3
-
-
0032989265
-
A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat
-
(1999)
Diabetes
, vol.48
, pp. 1415-1424
-
-
Brown, K.K.1
Henke, B.R.2
Blanchard, S.G.3
Cobb, J.E.4
Mook, R.5
Kaldor, I.6
Kliewer, S.A.7
Lehmann, J.M.8
Lenhard, J.M.9
Harrington, W.W.10
Novak, P.J.11
Faison, W.12
Binz, J.G.13
Hashim, M.A.14
Oliver, W.O.15
Brown, H.R.16
Parks, D.J.17
Plunket, K.D.18
Tong, W.Q.19
Menius, J.A.20
Adkison, K.21
Noble, S.A.22
Willson, T.M.23
more..
-
5
-
-
0032498230
-
The enhanceosome and transcriptional synergy
-
(1998)
Cell
, vol.92
, pp. 5-8
-
-
Carey, M.1
-
8
-
-
7844232968
-
N-(2-Benzoylphenyl)-L-tyrosine PPARγ agonists. 3. Structure-activity relationship and optimization of the N-aryl substituent
-
(1998)
J. Med. Chem.
, vol.41
, pp. 5055-5069
-
-
Cobb, J.E.1
Blanchard, S.G.2
Boswell, E.G.3
Brown, K.K.4
Charifson, P.S.5
Cooper, J.P.6
Collins, J.L.7
Dezube, M.8
Henke, B.R.9
Hull-Ryde, E.A.10
Lake, D.H.11
Lenhard, J.M.12
Oliver W., Jr.13
Oplinger, J.14
Pentti, M.15
Parks, D.J.16
Plunket, K.D.17
Tong, W.Q.18
-
9
-
-
7844226652
-
N-(2-Benzoyl-phenyl)-L-tyrosine PPAR-γ agonists. 2. Structure-activity relationship and optimization of the phenyl alkyl ether moiety
-
(1998)
J. Med. Chem.
, vol.41
, pp. 5037-5054
-
-
Collins, J.L.1
Blanchard, S.G.2
Boswell, G.E.3
Charifson, P.S.4
Cobb, J.E.5
Henke, B.R.6
Hull-Ryde, E.A.7
Kazmierski, W.M.8
Lake, D.H.9
Leesnitzer, L.M.10
Lehmann, J.11
Lenhard, J.M.12
Orband-Miller, L.A.13
Gray-Nunez, Y.14
Parks, D.J.15
Plunkett, K.D.16
Tong, W.Q.17
-
10
-
-
0033616795
-
Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3951-3956
-
-
Demetri, G.D.1
Fletcher, C.D.2
Mueller, E.3
Sarraf, P.4
Naujoks, R.5
Campbell, N.6
Spiegelman, B.M.7
Singer, S.8
-
12
-
-
1842295133
-
Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2166-2176
-
-
DiRenzo, J.1
Soderstrom, M.2
Kurokawa, R.3
Ogliastro, M.H.4
Ricote, M.5
Ingrey, S.6
Horlein, A.7
Rosenfeld, M.G.8
Glass, C.K.9
-
14
-
-
0032555196
-
Ligands for peroxisome proliferator-activated receptor gamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8806-8811
-
-
Elstner, E.1
Muller, C.2
Koshizuka, K.3
Williamson, E.A.4
Park, D.5
Asou, H.6
Shintaku, P.7
Said, J.W.8
Heber, D.9
Koeffler, H.P.10
-
17
-
-
0033515428
-
Increasing the complexity of coactivation in nuclear receptor signaling
-
(1999)
Cell
, vol.97
, pp. 5-8
-
-
Freedman, L.P.1
-
18
-
-
0033681001
-
Asymmetry in the PPAR-gamma/RXR-alpha structure reveals the molecular basis of heterodimerization among nuclear receptors
-
(2000)
Mol. Cell
, vol.5
, pp. 545-555
-
-
Gampe, R.T.J.1
Montana, V.G.2
Lambert, M.H.3
Miller, A.B.4
Bledsoe, R.K.5
Milburn, M.V.6
Kliewer, S.A.7
Willson, T.A.8
Xu, E.H.9
-
21
-
-
0033010438
-
A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation
-
(1999)
Mol. Cell
, vol.3
, pp. 97-108
-
-
Gu, W.1
Malik, S.2
Ito, M.3
Yuan, C.X.4
Fondell, J.D.5
Zhang, X.6
Martinez, E.7
Qin, J.8
Roeder, R.G.9
-
22
-
-
7844224790
-
N-(2-Benzoylphenyl)-L-tyrosine PPARγ agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents
-
(1998)
J. Med. Chem.
, vol.41
, pp. 5020-5036
-
-
Henke, B.R.1
Blanchard, S.G.2
Brackeen, M.F.3
Brown, K.K.4
Cobb, J.E.5
Collins, J.L.6
Harrington W.W., Jr.7
Hashim, M.A.8
Hull-Ryde, E.A.9
Kaldor, I.10
Kliewer, S.A.11
Lake, D.H.12
Leesnitzer, L.M.13
Lehmann, J.M.14
Lenhard, J.M.15
Orband-Miller, L.A.16
Miller, J.F.17
Mook R.A., Jr.18
Noble, S.A.19
Oliver W., Jr.20
Parks, D.J.21
Plunket, K.D.22
Szewczyk, J.R.23
Willson, T.M.24
more..
-
23
-
-
0033595261
-
Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase
-
(1999)
Nature
, vol.400
, pp. 378-382
-
-
Huang, J.T.1
Welch, J.S.2
Ricote, M.3
Binder, C.J.4
Willson, T.M.5
Kelly, C.6
Witztum, J.L.7
Funk, C.D.8
Conrad, D.9
Glass, C.K.10
-
24
-
-
0028584172
-
Evidence for a common mechanism of action for fatty acids and thiazolidinedione antidiabetic agents on gene expression in preadipose cells
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 1070-1076
-
-
Ibrahimi, A.1
Teboul, L.2
Galliard, D.3
Amri, E.Z.4
Ailhaud, G.5
Young, P.6
Cawthorne, M.A.7
Grimaldi, P.A.8
-
35
-
-
0031993322
-
Terminal differentiation of human breast cancer through PPAR gamma
-
(1998)
Mol. Cell
, vol.1
, pp. 465-470
-
-
Mueller, E.1
Sarraf, P.2
Tontonoz, P.3
Evans, R.M.4
Martin, K.J.5
Zhang, M.6
Fletcher, C.7
Singer, S.8
Spiegelman, B.M.9
-
36
-
-
17444442152
-
Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists
-
(1997)
Nature
, vol.386
, pp. 407-410
-
-
Mukherjee, R.1
Davies, P.J.2
Crombie, D.L.3
Bischoff, E.D.4
Cesario, R.M.5
Jow, L.6
Hamann, L.G.7
Boehm, M.F.8
Mondon, C.E.9
Nadzan, A.M.10
Paterniti J.R., Jr.11
Heyman, R.A.12
-
38
-
-
0032505096
-
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma
-
(1998)
Nature
, vol.395
, pp. 137-143
-
-
Nolte, R.T.1
Wisely, G.B.2
Westin, S.3
Cobb, J.E.4
Lambert, M.H.5
Kurokawa, R.6
Rosenfeld, M.G.7
Willson, T.M.8
Glass, C.K.9
Milburn, M.V.10
-
41
-
-
0033614417
-
Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex
-
(1999)
Nature
, vol.398
, pp. 824-828
-
-
Rachez, C.1
Lemon, B.D.2
Suldan, Z.3
Bromleigh, V.4
Gamble, M.5
Naar, A.M.6
Erdjument-Bromage, H.7
Tempst, P.8
Freedman, L.P.9
-
42
-
-
0032525781
-
A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system
-
(1998)
Genes Dev.
, vol.12
, pp. 1787-1800
-
-
Rachez, C.1
Suldan, Z.2
Ward, J.3
Chang, C.P.4
Burakov, D.5
Erdjument-Bromage, H.6
Tempst, P.7
Freedman, L.P.8
-
43
-
-
0031813879
-
Transactivation by retinoid X receptor-peroxisome proliferator-activated receptor gamma (PPARγ) heterodimers: Intermolecular synergy requires only the PPARγ hormone-dependent activation function
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3483-3494
-
-
Schulman, I.G.1
Shao, G.2
Heyman, R.A.3
-
46
-
-
12644265334
-
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 237-241
-
-
Tontonoz, P.1
Singer, S.2
Forman, B.M.3
Sarraf, P.4
Fletcher, J.A.5
Fletcher, C.D.6
Brun, R.P.7
Mueller, E.8
Altiok, S.9
Oppenheim, H.10
Evans, R.M.11
Spiegelman, B.M.12
-
47
-
-
0033525687
-
Competition between thyroid hormone receptor-associated protein (TRAP) 220 and transcriptional intermediary factor (TIF) 2 for binding to nuclear receptors. Implications for the recruitment of TRAP and p160 coactivator complexes
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 6667-6677
-
-
Treuter, E.1
Johansson, L.2
Thomsen, J.S.3
Warnmark, A.4
Leers, J.5
Pelto-Huikko, M.6
Sjoberg, M.7
Wright, A.P.8
Spyrou, G.9
Gustafsson, J.A.10
-
52
-
-
0030062325
-
The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones
-
(1996)
J. Med. Chem.
, vol.39
, pp. 665-668
-
-
Willson, T.M.1
Cobb, J.E.2
Cowan, D.J.3
Wiethe, R.W.4
Correa, I.D.5
Prakash, S.R.6
Beck, K.D.7
Moore, L.B.8
Kliewer, S.A.9
Lehmann, J.M.10
-
53
-
-
0028802627
-
Differential activation of peroxisome proliferator-activated receptors by eicosanoids
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23975-23983
-
-
Yu, K.1
Bayona, W.2
Kallen, C.B.3
Harding, H.P.4
Ravera, C.P.5
MeMahon, G.6
Brown, M.7
Lazar, M.A.8
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