-
1
-
-
0026726806
-
Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation
-
Allan, G. F., X. Leng, S. Y. Tasi, N. L. Weigel, D. P. Edwards, M.-J. Tsai, and B. W. O'Malley. 1992. Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation. J. Biol. Chem. 267:19513-19520.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 19513-19520
-
-
Allan, G.F.1
Leng, X.2
Tasi, S.Y.3
Weigel, N.L.4
Edwards, D.P.5
Tsai, M.-J.6
O'Malley, B.W.7
-
2
-
-
0027081043
-
Ligand-dependent conformational changes in the progesterone receptor are necessary events that follow DNA binding
-
Allan, G. F., X. Leng, S. Y. Tsai, N. L. Weigel, D. P. Edwards, M.-J. Tsai, and B. W. O'Malley. 1992. Ligand-dependent conformational changes in the progesterone receptor are necessary events that follow DNA binding. Proc. Natl. Acad Sci. USA 89:11750-11754.
-
(1992)
Proc. Natl. Acad Sci. USA
, vol.89
, pp. 11750-11754
-
-
Allan, G.F.1
Leng, X.2
Tsai, S.Y.3
Weigel, N.L.4
Edwards, D.P.5
Tsai, M.-J.6
O'Malley, B.W.7
-
3
-
-
0028988482
-
The τc activation domain of the thyroid hormone receptor is required for the release of a putative corepressor(s) necessary for transcriptional silencing
-
Baniahmad, A., X. Leng, T. P. Burris, S. Y. Tsai, M.-J. Tsai, and B. W. O'Malley. 1995. The τc activation domain of the thyroid hormone receptor is required for the release of a putative corepressor(s) necessary for transcriptional silencing. Mol. Cell. Biol. 15:76-86.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 76-86
-
-
Baniahmad, A.1
Leng, X.2
Burris, T.P.3
Tsai, S.Y.4
Tsai, M.-J.5
O'Malley, B.W.6
-
4
-
-
0030480969
-
The CBP co-activator is a histone acetyltransferase
-
Bannister, A. J., and T. Kouzarides. 1997. The CBP co-activator is a histone acetyltransferase. Nature 284:641-643.
-
(1997)
Nature
, vol.284
, pp. 641-643
-
-
Bannister, A.J.1
Kouzarides, T.2
-
5
-
-
0027521287
-
Transcriptional activation hy the estrogen receptor requires a conformational change in the ligand binding domain
-
Beekman, J. M., G. F. Allan, S. Y. Tsai, M.-J. Tsai, and B. W. O'Malley. 1993. Transcriptional activation hy the estrogen receptor requires a conformational change in the ligand binding domain. Mol. Endocrinol. 7:1266-1274.
-
(1993)
Mol. Endocrinol.
, vol.7
, pp. 1266-1274
-
-
Beekman, J.M.1
Allan, G.F.2
Tsai, S.Y.3
Tsai, M.-J.4
O'Malley, B.W.5
-
6
-
-
0029097177
-
Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells
-
Boehm, M. F., L. Zhang, L. Zhi, M. R. McClurg, E. Berger, M. Wagoner, D. E. Mais, C. M. Suto, P. J. A. Davies, R. A. Heyman, and A. M. Nadzan. 1995. Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells. J. Med. Chem. 38:3145-3155.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 3145-3155
-
-
Boehm, M.F.1
Zhang, L.2
Zhi, L.3
McClurg, M.R.4
Berger, E.5
Wagoner, M.6
Mais, D.E.7
Suto, C.M.8
Davies, P.J.A.9
Heyman, R.A.10
Nadzan, A.M.11
-
7
-
-
0029012163
-
Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha
-
Bourguet, W., M. Ruff, P. Chambon, H. Gronemeyer, and D. Moras. 1995. Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha. Nature 375:377-382.
-
(1995)
Nature
, vol.375
, pp. 377-382
-
-
Bourguet, W.1
Ruff, M.2
Chambon, P.3
Gronemeyer, H.4
Moras, D.5
-
8
-
-
0032498230
-
The enhanceosome and transcriptional synergy
-
Carey, M. 1998. The enhanceosome and transcriptional synergy. Cell 92:5-8.
-
(1998)
Cell
, vol.92
, pp. 5-8
-
-
Carey, M.1
-
9
-
-
0029817669
-
Role of CBP/P300 in nuclear receptor signaling
-
Chakravarti, D., V. J. LaMorte, M. C. Nelson, T. Nakajima, I. G. Schulman, H. Juguilon, M. Montminy, and R. M. Evans. 1996. Role of CBP/P300 in nuclear receptor signaling. Nature 383:99-103.
-
(1996)
Nature
, vol.383
, pp. 99-103
-
-
Chakravarti, D.1
LaMorte, V.J.2
Nelson, M.C.3
Nakajima, T.4
Schulman, I.G.5
Juguilon, H.6
Montminy, M.7
Evans, R.M.8
-
10
-
-
0028202490
-
Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival
-
Chawla, A., and M. A. Lazar. 1994. Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival. Proc. Natl. Acad. Sci. USA 91:1786-1790.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 1786-1790
-
-
Chawla, A.1
Lazar, M.A.2
-
11
-
-
0030740253
-
Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300
-
Chen, H., R. J. Lin, R. L. Schiltz, D. Chakravarti, A. Nash, L. Nagy, M. L. Privalsky, Y. Nakatani, and R. M. Evans. 1997. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell 90:569-580.
-
(1997)
Cell
, vol.90
, pp. 569-580
-
-
Chen, H.1
Lin, R.J.2
Schiltz, R.L.3
Chakravarti, D.4
Nash, A.5
Nagy, L.6
Privalsky, M.L.7
Nakatani, Y.8
Evans, R.M.9
-
12
-
-
0029097233
-
A transcriptional co-repressor that interacts with nuclear hormone receptors
-
Chen, J. D., and R. M. Evans. 1995. A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377:454-457.
-
(1995)
Nature
, vol.377
, pp. 454-457
-
-
Chen, J.D.1
Evans, R.M.2
-
13
-
-
0029794881
-
SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers
-
Chen, J. D., K. Umesono, and R. M. Evans. 1996. SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers. Proc. Natl. Acad. Sci. USA 93:7567-7571.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7567-7571
-
-
Chen, J.D.1
Umesono, K.2
Evans, R.M.3
-
14
-
-
0029930872
-
Modulation of nuclear receptor interactions by ligands: Kinetic analysis using surface plasmon resonance
-
Cheskis, B., and L. P. Freedman. 1996. Modulation of nuclear receptor interactions by ligands: kinetic analysis using surface plasmon resonance. Biochemistry 35:3309-3318.
-
(1996)
Biochemistry
, vol.35
, pp. 3309-3318
-
-
Cheskis, B.1
Freedman, L.P.2
-
15
-
-
0027526297
-
Functional inhibition of retinoic acid response by dominant negative retinoic receptor mutants
-
Damm, K., R. A. Heyman, K. Umesono, and R. A. Evans. 1993. Functional inhibition of retinoic acid response by dominant negative retinoic receptor mutants. Proc. Natl. Acad. Sci. USA 90:2989-2993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2989-2993
-
-
Damm, K.1
Heyman, R.A.2
Umesono, K.3
Evans, R.A.4
-
16
-
-
1842295133
-
Peroxisome proliferator-activated receptors and retinoid acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors
-
DiRenzo, J., M. Soderstrom, R. Kurokawa, M.-H. Ogliastro, M. Ricote, S. Ingrey, A. Horlein, M. G. Rosenfeld, and C. K. Glass. 1997. Peroxisome proliferator-activated receptors and retinoid acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors. Mol. Cell. Biol. 17:2166-2176.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2166-2176
-
-
DiRenzo, J.1
Soderstrom, M.2
Kurokawa, R.3
Ogliastro, M.-H.4
Ricote, M.5
Ingrey, S.6
Horlein, A.7
Rosenfeld, M.G.8
Glass, C.K.9
-
17
-
-
0031439111
-
P300 functions as a coactivator for the peroxisome proliferator-activated receptor α
-
Dowell, P., J. E. Ishmael, D. Avram, V. J. Peterson, D. J. Nevrivy, and M. Leid. 1997. p300 functions as a coactivator for the peroxisome proliferator-activated receptor α. J. Biol. Chem. 272:33435-33443.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 33435-33443
-
-
Dowell, P.1
Ishmael, J.E.2
Avram, D.3
Peterson, V.J.4
Nevrivy, D.J.5
Leid, M.6
-
19
-
-
0029002298
-
Unique response pathways are established by allosteric interactions among nuclear hormone receptors
-
Forman, B. M., K. Umesono, J. Chen, and R. M. Evans. 1995. Unique response pathways are established by allosteric interactions among nuclear hormone receptors. Cell 81:541-550.
-
(1995)
Cell
, vol.81
, pp. 541-550
-
-
Forman, B.M.1
Umesono, K.2
Chen, J.3
Evans, R.M.4
-
20
-
-
0026703387
-
A ligand-induced conformational change in the estrogen receptor is localized in the steroid binding domain
-
Fritsch, M. C., C. M. Leary, J. D. Furlow, H. Ahrens, T. J. Schuh, G. C. Mueller, and J. Gorski. 1992. A ligand-induced conformational change in the estrogen receptor is localized in the steroid binding domain. Biochemistry 31:5303-5311.
-
(1992)
Biochemistry
, vol.31
, pp. 5303-5311
-
-
Fritsch, M.C.1
Leary, C.M.2
Furlow, J.D.3
Ahrens, H.4
Schuh, T.J.5
Mueller, G.C.6
Gorski, J.7
-
22
-
-
0028840419
-
Transcriptional coactivators in yeast and beyond
-
Guarente, L. 1995. Transcriptional coactivators in yeast and beyond. Trends Biochem. Sci. 20:517-521.
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 517-521
-
-
Guarente, L.1
-
23
-
-
0029858911
-
p300 is a component of an eslrogen receptor activator complex
-
Hanstein, B., R. Eckner, J. DiRenzo, S. Halachmi, H. Liu, B. Searcy, R. Kurokawa, and M. Brown. 1996. p300 is a component of an eslrogen receptor activator complex. Proc. Natl. Acad. Sci. USA 93:11540-11545.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11540-11545
-
-
Hanstein, B.1
Eckner, R.2
DiRenzo, J.3
Halachmi, S.4
Liu, H.5
Searcy, B.6
Kurokawa, R.7
Brown, M.8
-
24
-
-
0027411327
-
Synergism in transcriptional activation: A kinetic view
-
Herschlag, D., and F. B. Johnson. 1993. Synergism in transcriptional activation: a kinetic view. Genes Dev. 7:173-179.
-
(1993)
Genes Dev.
, vol.7
, pp. 173-179
-
-
Herschlag, D.1
Johnson, F.B.2
-
25
-
-
0030949836
-
GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors
-
Hong, H., K. Kohli, M. J. Garabedian, and M. R. Stallcup. 1997. GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors. Mol. Cell. Biol. 17:2735-2744.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2735-2744
-
-
Hong, H.1
Kohli, K.2
Garabedian, M.J.3
Stallcup, M.R.4
-
26
-
-
0028212908
-
The role of activators in RNA polymerase II transcription complexes
-
Hori, R., and M. Carey. 1994. The role of activators in RNA polymerase II transcription complexes. Curr. Opin. Genet. Dev. 4:236-244.
-
(1994)
Curr. Opin. Genet. Dev.
, vol.4
, pp. 236-244
-
-
Hori, R.1
Carey, M.2
-
27
-
-
0029132202
-
Hormone-independent repression by the thyroid hormone receptor is mediated by a nuclear receptor co-repressor N-COR
-
Horlein, A. J., A. M. Naar, T. Heinzel, J. Torchia, B. Gloss, R. Kurokawa, A. Ryan, Y. Kamai, M. Soderstrom, C. K. Glass, and M. G. Rosenfeld. 1995. Hormone-independent repression by the thyroid hormone receptor is mediated by a nuclear receptor co-repressor N-COR. Nature 377:397-404.
-
(1995)
Nature
, vol.377
, pp. 397-404
-
-
Horlein, A.J.1
Naar, A.M.2
Heinzel, T.3
Torchia, J.4
Gloss, B.5
Kurokawa, R.6
Ryan, A.7
Kamai, Y.8
Soderstrom, M.9
Glass, C.K.10
Rosenfeld, M.G.11
-
28
-
-
0242587820
-
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors
-
Kamei, Y., L. Xu, T. Heinzel, J. Torchia, R. Kurokawa, B. Gloss, S.-C. Lin, R. A. Heyman, D. W. Rose, C. K. Glass, and M. G. Rosenfeld. 1996. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85:403-414.
-
(1996)
Cell
, vol.85
, pp. 403-414
-
-
Kamei, Y.1
Xu, L.2
Heinzel, T.3
Torchia, J.4
Kurokawa, R.5
Gloss, B.6
Lin, S.-C.7
Heyman, R.A.8
Rose, D.W.9
Glass, C.K.10
Rosenfeld, M.G.11
-
29
-
-
0030029419
-
Adapter-mediated recruitment of RNA polymerase II to a signal-dependent activator
-
Kee, B. L., J. Arias, and M. R. Montminy. 1996. Adapter-mediated recruitment of RNA polymerase II to a signal-dependent activator. J. Biol. Chem. 271:2373-2375.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2373-2375
-
-
Kee, B.L.1
Arias, J.2
Montminy, M.R.3
-
30
-
-
0028012039
-
Different agonist- and antagonist-induced conformational changes in retinoic acid receptors analyzed by protease mapping
-
Keidel, S., P. LeMotte, and C. Apfel. 1994. Different agonist-and antagonist-induced conformational changes in retinoic acid receptors analyzed by protease mapping. Mol. Cell. Biol. 14:287-298.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 287-298
-
-
Keidel, S.1
Lemotte, P.2
Apfel, C.3
-
31
-
-
0028972026
-
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation
-
Kliewer, S. A., J. M. Lenhard, T. M. Willson, I. Patel, D. C. Morris, and J. Lehmann. 1995. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell 83:813-819.
-
(1995)
Cell
, vol.83
, pp. 813-819
-
-
Kliewer, S.A.1
Lenhard, J.M.2
Willson, T.M.3
Patel, I.4
Morris, D.C.5
Lehmann, J.6
-
32
-
-
0026705751
-
Convergence of 9-cis retinoic acid and peroxisome proliferator signaling pathways through heterodimer formation of their receptors
-
Kliewer, S. A., K. Umesono, D. J. Noonan, R. A. Heyman, and R. A. Evans. 1992. Convergence of 9-cis retinoic acid and peroxisome proliferator signaling pathways through heterodimer formation of their receptors. Nature 358:771-774.
-
(1992)
Nature
, vol.358
, pp. 771-774
-
-
Kliewer, S.A.1
Umesono, K.2
Noonan, D.J.3
Heyman, R.A.4
Evans, R.A.5
-
33
-
-
0032579292
-
Transcription factor-specific requirements for coactivators and their acetyltransferase functions
-
Korzus, E., J. Torchia, D. W. Rose, L. Xu, R. Kurokawa, E. M. McInerney, T. M. Mullen, C. K. Glass, and M. G. Rosenfeld. 1998. Transcription factor-specific requirements for coactivators and their acetyltransferase functions. Science 279:703-707.
-
(1998)
Science
, vol.279
, pp. 703-707
-
-
Korzus, E.1
Torchia, J.2
Rose, D.W.3
Xu, L.4
Kurokawa, R.5
McInerney, E.M.6
Mullen, T.M.7
Glass, C.K.8
Rosenfeld, M.G.9
-
34
-
-
0032579289
-
Differential use of CREB binding protein-coactivator complexes
-
Kurakawa, R., D. Kalafus, M. H. Ogliastro, C. Kioussi, L. Xu, J. Torchia, M. G. Rosenfeld, and C. K. Glass. 1998. Differential use of CREB binding protein-coactivator complexes. Science 279:700-703.
-
(1998)
Science
, vol.279
, pp. 700-703
-
-
Kurakawa, R.1
Kalafus, D.2
Ogliastro, M.H.3
Kioussi, C.4
Xu, L.5
Torchia, J.6
Rosenfeld, M.G.7
Glass, C.K.8
-
35
-
-
0029154931
-
A co-repressor specifies polarity-specific activities of retinoic acid receptors
-
Kurokawa, R., M. Soderstrom, A. Horlein, S. Halachmi, M. Brown, M. G. Rosenfeld, and C. K. Glass. 1995. A co-repressor specifies polarity-specific activities of retinoic acid receptors. Nature 377:451-457.
-
(1995)
Nature
, vol.377
, pp. 451-457
-
-
Kurokawa, R.1
Soderstrom, M.2
Horlein, A.3
Halachmi, S.4
Brown, M.5
Rosenfeld, M.G.6
Glass, C.K.7
-
36
-
-
0029740183
-
Activation of specific RXR heterodimers by an antagonist of RXR homodimers
-
Lala, D. S., R. Mukherjee, I. G. Schulman, S. S. Canan-Koch, L. J. Dardashti, A. M. Nadzan, G. E. Croston, R. M. Evans, and R. A. Heyman. 1996. Activation of specific RXR heterodimers by an antagonist of RXR homodimers. Nature 383:450-453.
-
(1996)
Nature
, vol.383
, pp. 450-453
-
-
Lala, D.S.1
Mukherjee, R.2
Schulman, I.G.3
Canan-Koch, S.S.4
Dardashti, L.J.5
Nadzan, A.M.6
Croston, G.E.7
Evans, R.M.8
Heyman, R.A.9
-
37
-
-
0029115655
-
9-cis retinoic acid signaling: Changing partners causes some excitement
-
Leblanc, B. P., and H. G. Stunnenberg. 1995. 9-cis retinoic acid signaling: changing partners causes some excitement. Genes Dev. 9:1811-1816.
-
(1995)
Genes Dev.
, vol.9
, pp. 1811-1816
-
-
Leblanc, B.P.1
Stunnenberg, H.G.2
-
38
-
-
0027222793
-
Structure of the retinoid X receptorα DNA binding domain: A helix required for homodimeric DNA binding
-
Lee, M. S., S. A. Kliewer, J. Provencal, P. E. Wright, and R. M. Evans. 1993. Structure of the retinoid X receptorα DNA binding domain: a helix required for homodimeric DNA binding. Science 260:1117-1121.
-
(1993)
Science
, vol.260
, pp. 1117-1121
-
-
Lee, M.S.1
Kliewer, S.A.2
Provencal, J.3
Wright, P.E.4
Evans, R.M.5
-
39
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPARγ)
-
Lehmann, J. M., L. B. Moore, T. A. Smith-Oliver, W. O. Wilkison, T. M. Willson, and S. A. Kliewer. 1995. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPARγ). J. Biol. Chem. 270:12953-12956.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
40
-
-
0028336807
-
Ligand-induced alteration of the protease sensitivity of retinoid X receptorα
-
Leid, M. 1994. Ligand-induced alteration of the protease sensitivity of retinoid X receptorα. J. Biol. Chem. 269:14175-14181.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 14175-14181
-
-
Leid, M.1
-
41
-
-
0027754125
-
Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptor
-
Leng, X., S. Y. Tsai, B. W. O'Malley, and M.-J. Tsai. 1993. Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptor. J. Steroid Biochem. Mol. Biol. 46:643-661.
-
(1993)
J. Steroid Biochem. Mol. Biol.
, vol.46
, pp. 643-661
-
-
Leng, X.1
Tsai, S.Y.2
O'Malley, B.W.3
Tsai, M.-J.4
-
42
-
-
0031041075
-
Regulating adipogenesis
-
Mandrup, S., and M. D. Lane. 1997. Regulating adipogenesis. J. Biol. Chem. 272:5367-5370.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 5367-5370
-
-
Mandrup, S.1
Lane, M.D.2
-
43
-
-
0029562554
-
The RXR heterodimers and orphan receptors
-
Mangelsdorf, D. J., and R. M. Evans. 1995. The RXR heterodimers and orphan receptors. Cell 83:841-850.
-
(1995)
Cell
, vol.83
, pp. 841-850
-
-
Mangelsdorf, D.J.1
Evans, R.M.2
-
44
-
-
0012473279
-
The nuclear receptor superfamily: The second decade
-
Mangelsdorf, D. J., C. Thummel, M. Beato, P. Herrlich, G. Schutz, K. Umesono, P. Kastner, M. Mark, P. Chambon, and R. M. Evans. 1995. The nuclear receptor superfamily: the second decade. Cell 83:835-839.
-
(1995)
Cell
, vol.83
, pp. 835-839
-
-
Mangelsdorf, D.J.1
Thummel, C.2
Beato, M.3
Herrlich, P.4
Schutz, G.5
Umesono, K.6
Kastner, P.7
Mark, M.8
Chambon, P.9
Evans, R.M.10
-
45
-
-
0031038518
-
Retinoid X receptor (RXR) within the RXR-retinoic acid receptor heterodimer binds its ligand and enhances retinoid-dependent gene expression
-
Minucci, S., M. Leid, R. Toyama, J.-P. Saint-Jeannet, V. J. Peterson, V. Horn, J. E. Ishmael, N. Bhattacharyya, A. Dey, I. B. Dawid, and K. Ozato. 1997. Retinoid X receptor (RXR) within the RXR-retinoic acid receptor heterodimer binds its ligand and enhances retinoid-dependent gene expression. Mol. Cell. Biol. 17:644-655.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 644-655
-
-
Minucci, S.1
Leid, M.2
Toyama, R.3
Saint-Jeannet, J.-P.4
Peterson, V.J.5
Horn, V.6
Ishmael, J.E.7
Bhattacharyya, N.8
Dey, A.9
Dawid, I.B.10
Ozato, K.11
-
46
-
-
17444442152
-
Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists
-
Mukherjee, R., P. J. A. Davies, D. L. Crombie, E. D. Bischoff, R. M. Cesario, L. Jow, L. G. Hamann, M. F. Boehm, C. E. Mondon, A. M. Nadzan, J. R. Paterniti, Jr., and R. A. Heyman. 1997. Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists. Nature 386:407-410.
-
(1997)
Nature
, vol.386
, pp. 407-410
-
-
Mukherjee, R.1
Davies, P.J.A.2
Crombie, D.L.3
Bischoff, E.D.4
Cesario, R.M.5
Jow, L.6
Hamann, L.G.7
Boehm, M.F.8
Mondon, C.E.9
Nadzan, A.M.10
Paterniti Jr., J.R.11
Heyman, R.A.12
-
47
-
-
0030967951
-
RNA helicase A mediates the association of CBP with RNA polymerase II
-
Nakajima, T., C. Uchida, S. F. Anderson, C.-G. Lee, J. Hurwitz, J. D. Parvin, and M. Montminy. 1997. RNA helicase A mediates the association of CBP with RNA polymerase II. Cell 90:1107-1112.
-
(1997)
Cell
, vol.90
, pp. 1107-1112
-
-
Nakajima, T.1
Uchida, C.2
Anderson, S.F.3
Lee, C.-G.4
Hurwitz, J.5
Parvin, J.D.6
Montminy, M.7
-
48
-
-
0030902507
-
Analysis of a cAMP-responsive activator reveals a two-component mechanism for transcriptional induction via signal-dependent factors
-
Nakajima, T., C. Uchida, S. F. Anderson, J. D. Parvin, and M. Montminy. 1997. Analysis of a cAMP-responsive activator reveals a two-component mechanism for transcriptional induction via signal-dependent factors. Genes Dev. 11:738-747.
-
(1997)
Genes Dev.
, vol.11
, pp. 738-747
-
-
Nakajima, T.1
Uchida, C.2
Anderson, S.F.3
Parvin, J.D.4
Montminy, M.5
-
49
-
-
0030606239
-
The transcriptional coactivator p300 and CBP are histone acetyltransferases
-
Ogryzko, V. V., R. L. Schitz, V. Russanova, B. H. Howard, and Y. Nakatani. 1996. The transcriptional coactivator p300 and CBP are histone acetyltransferases. Cell 87:953-959.
-
(1996)
Cell
, vol.87
, pp. 953-959
-
-
Ogryzko, V.V.1
Schitz, R.L.2
Russanova, V.3
Howard, B.H.4
Nakatani, Y.5
-
50
-
-
0028846193
-
Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
-
Onate, S. A., S. Y. Tsai, M.-J. Tsai, and B. W. O'Malley. 1995. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270:1354-1357.
-
(1995)
Science
, vol.270
, pp. 1354-1357
-
-
Onate, S.A.1
Tsai, S.Y.2
Tsai, M.-J.3
O'Malley, B.W.4
-
51
-
-
0031929308
-
Engineering novel specificities for ligand-activated transcription in the nuclear hormone receptor RXR
-
Peet, D. J., D. F. Doyle, D. R. Corey, and D. J. Mangelsdorf. 1998. Engineering novel specificities for ligand-activated transcription in the nuclear hormone receptor RXR. Chem. Biol. 5:13-21.
-
(1998)
Chem. Biol.
, vol.5
, pp. 13-21
-
-
Peet, D.J.1
Doyle, D.F.2
Corey, D.R.3
Mangelsdorf, D.J.4
-
52
-
-
0030960672
-
Transcriptional activation by recruitment
-
Ptashne, M., and A. Gann. 1997. Transcriptional activation by recruitment. Nature 386:569-577.
-
(1997)
Nature
, vol.386
, pp. 569-577
-
-
Ptashne, M.1
Gann, A.2
-
53
-
-
0029643780
-
Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid
-
Renaud, J.-P., N. Rochel, M. Ruff, V. Vivat, P. Chambon, H. Gronemeyer, and D. Moras. 1995. Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid. Nature 378:681-689.
-
(1995)
Nature
, vol.378
, pp. 681-689
-
-
Renaud, J.-P.1
Rochel, N.2
Ruff, M.3
Vivat, V.4
Chambon, P.5
Gronemeyer, H.6
Moras, D.7
-
54
-
-
0029085038
-
Interactions between the retinoid X receptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation
-
Schulman, I. G., D. Chakravarti, H. Juguilon, A. Romo, and R. M. Evans. 1995. Interactions between the retinoid X receptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation. Proc. Natl. Acad. Sci. USA 92:8288-8292.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8288-8292
-
-
Schulman, I.G.1
Chakravarti, D.2
Juguilon, H.3
Romo, A.4
Evans, R.M.5
-
55
-
-
0029938795
-
Activation and repression by nuclear hormone receptors: Hormone modulates an equilibrium between active and repressive states
-
Schulman, I. G., H. Juguilon, and R. M. Evans. 1996. Activation and repression by nuclear hormone receptors: hormone modulates an equilibrium between active and repressive states. Mol. Cell. Biol. 16:3807-3818.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3807-3818
-
-
Schulman, I.G.1
Juguilon, H.2
Evans, R.M.3
-
56
-
-
0031043055
-
The phantom ligand effect: Allosteric control of transcription by the retinoid X receptor
-
Schulman, I. G., C. Li, J. W. R. Schwabe, and R. M. Evans. 1997. The phantom ligand effect: allosteric control of transcription by the retinoid X receptor. Genes Dev. 11:299-308.
-
(1997)
Genes Dev.
, vol.11
, pp. 299-308
-
-
Schulman, I.G.1
Li, C.2
Schwabe, J.W.R.3
Evans, R.M.4
-
57
-
-
84920309813
-
-
Unpublished observations
-
Schulman, I. G. Unpublished observations.
-
-
-
Schulman, I.G.1
-
58
-
-
0030113441
-
Transcriptional control: How nuclear receptors get turned on
-
Schwabe, J. W. R. 1996. Transcriptional control: how nuclear receptors get turned on. Curr. Biol. 6:372-374.
-
(1996)
Curr. Biol.
, vol.6
, pp. 372-374
-
-
Schwabe, J.W.R.1
-
59
-
-
0024384860
-
Steroid binding activity is retained in a 16-kDa fragment of the steroid binding domain of rat glucocorticoid receptor
-
Simons, S. S., F. D. Sistare, and P. K. Chakraboti. 1989. Steroid binding activity is retained in a 16-kDa fragment of the steroid binding domain of rat glucocorticoid receptor. J. Biol. Chem. 264:14493-14497.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 14493-14497
-
-
Simons, S.S.1
Sistare, F.D.2
Chakraboti, P.K.3
-
60
-
-
0029786690
-
CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription
-
Smith, C. L., S. A. Onate, M.-J. Tsai, and B. W. O'Malley. 1996. CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription. Proc. Natl. Acad. Sci. USA 93:8884-8888.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8884-8888
-
-
Smith, C.L.1
Onate, S.A.2
Tsai, M.-J.3
O'Malley, B.W.4
-
61
-
-
0030768745
-
Steroid receptor coactivator-1, is a histone acetyltransferase
-
Spencer, T. E., G. Jenster, M. M. Burcin, C. D. Allis, J. Zhou, C. A. Mizzen, N. J. McKenna, S. A. Onate, S.-Y. Tsai, M.-J. Tsai, and B. W. O'Malley. 1997. Steroid receptor coactivator-1, is a histone acetyltransferase. Nature 389:195-198.
-
(1997)
Nature
, vol.389
, pp. 195-198
-
-
Spencer, T.E.1
Jenster, G.2
Burcin, M.M.3
Allis, C.D.4
Zhou, J.5
Mizzen, C.A.6
McKenna, N.J.7
Onate, S.A.8
Tsai, S.-Y.9
Tsai, M.-J.10
O'Malley, B.W.11
-
62
-
-
0028348240
-
Distinct binding determinants for 9-cis retinoic acid are located within AF-2 of retinoic acid receptor α
-
Tate, B. F., G. Allenby, R. Janocha, S. Kazmer, J. Speck, L. J. Sturzenbecker, P. Abarzúa, A. A. Levin, and J. F. Grippo. 1994. Distinct binding determinants for 9-cis retinoic acid are located within AF-2 of retinoic acid receptor α. Mol. Cell. Biol. 14:2323-2330.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2323-2330
-
-
Tate, B.F.1
Allenby, G.2
Janocha, R.3
Kazmer, S.4
Speck, J.5
Sturzenbecker, L.J.6
Abarzúa, P.7
Levin, A.A.8
Grippo, J.F.9
-
63
-
-
0029050907
-
Mutagenesis of the ligand binding domain of the human retinoic acid receptor α identifies critical residues for 9-cis-retinoic acid binding
-
Tate, B. F., and J. F. Grippo. 1995. Mutagenesis of the ligand binding domain of the human retinoic acid receptor α identifies critical residues for 9-cis-retinoic acid binding. J. Biol. Chem. 270:20258-20263.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 20258-20263
-
-
Tate, B.F.1
Grippo, J.F.2
-
64
-
-
0028641559
-
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
-
Tontonoz, P., E. Hu, and B. M. Spiegelman. 1994. Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell 79:1147-1156.
-
(1994)
Cell
, vol.79
, pp. 1147-1156
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
65
-
-
12644265334
-
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor γ and the retinoid X receptor
-
Tontonoz, P., S. Singer, B. M. Forman, P. Sarrag, J. A. Fletcher, C. D. Fletcher, R. P. Brun, E. Mueller, S. Alotiok, H. Oppenheim, R. M. Evans, and B. M. Spiegelman. 1997. Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor γ and the retinoid X receptor. Proc. Natl. Acad. Sci. USA 94:237-241.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 237-241
-
-
Tontonoz, P.1
Singer, S.2
Forman, B.M.3
Sarrag, P.4
Fletcher, J.A.5
Fletcher, C.D.6
Brun, R.P.7
Mueller, E.8
Alotiok, S.9
Oppenheim, H.10
Evans, R.M.11
Spiegelman, B.M.12
-
66
-
-
0030912539
-
The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function
-
Torchia, J., D. W. Rose, J. Inostroza, Y. Kamei, S. Westin, C. K. Glass, and M. G. Rosenfeld. 1997. The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function. Nature 387:677-684.
-
(1997)
Nature
, vol.387
, pp. 677-684
-
-
Torchia, J.1
Rose, D.W.2
Inostroza, J.3
Kamei, Y.4
Westin, S.5
Glass, C.K.6
Rosenfeld, M.G.7
-
68
-
-
0026653659
-
The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor
-
Vegeto, E., G. F. Allan, W. T. Schrader, M.-J. Tsai, D. P. McDonnell, and B. W. O'Malley. 1992. The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor. Cell 69:703-713.
-
(1992)
Cell
, vol.69
, pp. 703-713
-
-
Vegeto, E.1
Allan, G.F.2
Schrader, W.T.3
Tsai, M.-J.4
McDonnell, D.P.5
O'Malley, B.W.6
-
69
-
-
0029954339
-
TIF2, a 16-kDa transcriptional mediator for ligand-dependent activation function AF-2 of nuclear receptors
-
Voegel, J. J., M. J. S. Heine, C. Zechel, P. Chambon, and H. Gronemeyer. 1996. TIF2, a 16-kDa transcriptional mediator for ligand-dependent activation function AF-2 of nuclear receptors. EMBO J. 15:3667-3675.
-
(1996)
EMBO J.
, vol.15
, pp. 3667-3675
-
-
Voegel, J.J.1
Heine, M.J.S.2
Zechel, C.3
Chambon, P.4
Gronemeyer, H.5
-
70
-
-
0029643769
-
A structural role for hormone in the thyroid hormone receptor
-
Wagner, R. L., J. W. Apriletti, M. E. McGrath, B. L. West, J. D. Baxter, and R. J. Fletterick. 1995. A structural role for hormone in the thyroid hormone receptor. Nature 378:690-697.
-
(1995)
Nature
, vol.378
, pp. 690-697
-
-
Wagner, R.L.1
Apriletti, J.W.2
McGrath, M.E.3
West, B.L.4
Baxter, J.D.5
Fletterick, R.J.6
-
71
-
-
0031011661
-
Heterodimeric interaction between retinoid X receptor a and orphan nuclear receptor OR1 reveals dimerization-induced activation as a novel mechanism of nuclear receptor activation
-
Wiebel, F. F., and J.-A. Gustafsson. 1997. Heterodimeric interaction between retinoid X receptor a and orphan nuclear receptor OR1 reveals dimerization-induced activation as a novel mechanism of nuclear receptor activation. Mol. Cell. Biol. 17:3977-3986.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3977-3986
-
-
Wiebel, F.F.1
Gustafsson, J.-A.2
-
72
-
-
0031042762
-
Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR
-
Willy, P. J., and D. J. Mangelsdorf. 1997. Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR. Genes Dev. 11:289-298.
-
(1997)
Genes Dev.
, vol.11
, pp. 289-298
-
-
Willy, P.J.1
Mangelsdorf, D.J.2
-
73
-
-
0030056997
-
A canonical structure for the ligand-hinding domain of nuclear receptors
-
Wurtz, J.-M., W. Bourguet, J.-P. Renaud, V. Vivat, P. Chambon, D. Moras, and H. Gronemeyer. 1996. A canonical structure for the ligand-hinding domain of nuclear receptors. Nature Struct. Biol. 3:87-94.
-
(1996)
Nature Struct. Biol.
, vol.3
, pp. 87-94
-
-
Wurtz, J.-M.1
Bourguet, W.2
Renaud, J.-P.3
Vivat, V.4
Chambon, P.5
Moras, D.6
Gronemeyer, H.7
-
74
-
-
0029665857
-
A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
-
Yang, X.-J., V. V. Ogryzko, J.-I. Nishikawa, B. E. Howard, and Y. Nakatani. 1996. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 382:319-324.
-
(1996)
Nature
, vol.382
, pp. 319-324
-
-
Yang, X.-J.1
Ogryzko, V.V.2
Nishikawa, J.-I.3
Howard, B.E.4
Nakatani, Y.5
-
75
-
-
0029773871
-
The nuclear hormone receptor coactivator SRC-1 is a specific target of p300
-
Yao, T.-P., G. Ku, N. Zhou, and D. M. Livingston. 1996. The nuclear hormone receptor coactivator SRC-1 is a specific target of p300. Proc. Natl. Acad. Sci. USA 93:10626-10631.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10626-10631
-
-
Yao, T.-P.1
Ku, G.2
Zhou, N.3
Livingston, D.M.4
-
76
-
-
0027741191
-
Functional ecdysone receptor is the product of EcR and Ultraspiracle genes
-
Yao, T. P., B. M. Forman, Z. Jiang, L. Cherbas, J. D. Chen, M. McKeown, P. Cherbas, and R. M. Evans. 1993. Functional ecdysone receptor is the product of EcR and Ultraspiracle genes. Nature 366:476-479.
-
(1993)
Nature
, vol.366
, pp. 476-479
-
-
Yao, T.P.1
Forman, B.M.2
Jiang, Z.3
Cherbas, L.4
Chen, J.D.5
McKeown, M.6
Cherbas, P.7
Evans, R.M.8
-
77
-
-
0030991152
-
Stoichiometric and steric principles governing repression by nuclear hormone receptors
-
Zamir, I., J. Zhang, and M. A. Lazar. 1997. Stoichiometric and steric principles governing repression by nuclear hormone receptors. Genes Dev. 11:835-846.
-
(1997)
Genes Dev.
, vol.11
, pp. 835-846
-
-
Zamir, I.1
Zhang, J.2
Lazar, M.A.3
|