Biomechanical activation: An emerging paradigm in endothelial adhesion biology

Journal of Clinical Investigation

Volumn 99, Issue 8, 1997, Pages 1809-1813

  Gimbrone Jr , Michael A ^a   Nagel, Tobi ^a   Topper, James N ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ENDOTHELIN 1; ENDOTOXIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR B; PROTEIN PRECURSOR; THROMBOPLASTIN; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; VASCULAR CELL ADHESION MOLECULE 1;

CARDIOVASCULAR DISEASE; CELL ADHESION; CELL JUNCTION; ENDOTHELIUM CELL; HUMAN; INFLAMMATION; PRIORITY JOURNAL; REVIEW; SHEAR STRESS; VASCULAR ENDOTHELIUM;

EID: 1842330850     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119346     Document Type: Review

References (37)

1. Gimbrone, M.A., Jr. 1995. Vascular endothelium in health and disease. In Molecular Cardiovascular Medicine. E. Haber, editor. Scientific American Medicine, New York. 49-61.
2. Pober, J.S., and R.C. Cotran. 1990. Cytokines and endothelial cell biology. Physiol. Rev. 70:427-451.
3. Mantovani, A., F. Bussolino, and E. Dejana. 1992. Cytokine regulation of endothelial cell function. FASEB (Fed. Am. Soc. Exp. Biol.) J. 6:2591-2599.
4. Bevilacqua, M.P., J.S. Pober, M.E. Wheeler, R.S. Cotran, and M.A. Gimbrone, Jr. 1985. Interleukin-1 acts on cultured vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes and related leukocyte cell lines. J. Clin. Invest. 76:2003-2011.
5. Pober, J.S., M.P. Bevilacqua, D.L. Mendrick, L.A. Lapierre, W. Fiers, and M.A. Gimbrone, Jr. 1986. Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells. J. Immunol. 136:1680-1687.
6. Bevilacqua, M.P., S. Stengelin, M.A. Gimbrone, Jr., and B. Seed. 1989. Endothelial-leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science (Wash. DC). 243:1160-1165.
7. Luscinskas, F.W., and M.A. Gimbrone, Jr. 1996. Endothelial-dependent mechanisms of mononuclear leukocyte recruitment. Annu. Rev. Med. 47:413-421.
8. Cotran, R.S., M.A. Gimbrone, Jr., M.P. Bevilacqua, D. Mendrick, and J.S. Pober. 1986. Induction and detection of a human endothelial activation antigen in vivo. J. Exp. Med. 164:661-666.
9. Gimbrone, M.A., Jr., and J.N. Topper. 1997. Biology of the vessel wall: endothelium. In Molecular Basis of Heart Diseases. K.R. Chien, J.R. Breslow, J.M. Leiden, R.D. Rosenberg, and C. Seidman, editors. W.B. Saunders, Philadelphia. In press.
10. Cybulsky, M.I., and M.A. Gimbrone, Jr. 1991. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science (Wash. DC). 251:788-791.
11. Gearing, A.J.H., and W. Newman. 1993. Circulating adhesion molecules in disease. Immunol. Today. 14:506-512.
12. Davies, P.F. 1995. Flow-mediated endothelial mechanotransduction. Physiol. Rev. 75:519-560.
13. Resnick, N., and M.A. Gimbrone, Jr. 1995. Hemodynamic forces are complex regulators of endothelial gene expression. FASEB (Fed. Am. Soc. Exp. Biol.) J. 9:874-882.
14. Osawa, M., M. Masuda, N. Harada, R.B. Lopes, Y. Kano, and K. Fujiwara. 1997. Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) in mechanically stimulated vascular endothelial cells. Eur. J. Cell Biol. In press.
15. Satcher, R.L., Jr., S.R. Bussolari, M.A. Gimbrone, Jr., and C.F. Dewey, Jr. 1992. The distribution of fluid forces on model arterial endothelium using computational fluid dynamics. J. Biochem. Eng. 114:309-316.
16. Barbee, K.A., T. Mundel, R. Lal, and P.F. Davies. 1995. Subcellular distribution of shear stress at the surface of flow-aligned and nonaligned endothelial monolayers. Am. J. Physiol. 268:H1765-H1772.
17. Nagel, T., N. Resnick, W.J. Atkinson, C.F. Dewey, Jr., and M.A. Gimbrone, Jr. 1994. Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells. J. Clin. Invest. 94:885-891.
18. Topper, J.N., J. Cai, D. Falb, and M.A. Gimbrone, Jr. 1996. Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc. Natl. Acad. Sci. USA. 93:10417-10422.
19. Ando, J., H. Tsuboi, R. Korenaga, Y. Takada, N. Toyama-Sorimachi, M. Miyasaka, and A. Kamiya. 1994. Shear stress inhibits adhesion of cultured endothelial cells to lymphocytes by downregulating VCAM-1 expression. Am. J. Physiol. 267:C679-C687.
20. Ando, J., R. Korenaga, Y. Takada, and A. Kamiya. 1996. Down-regulation of VCAM-1 gene transcription by shear stress in cultured murine endothelial cells. J. Vasc. Res. 33(Suppl. 1):4a. (Abstr.)
21. Varner, S.E., R.M. Nerem, R.M. Medford, and R.W. Alexander. 1994. Laminar shear stress regulates VCAM-1 gene expression. Ann. Biomed. Eng. 22:40a. (Abstr.)
22. Marui, N., M. Offerman, R. Swerlick, C. Kunsch, C.A. Roxen, M. Ahmad, R.W. Alexander, and R.M. Medford. 1993. Vascular cell-adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant sensitive mechanism in human vascular endothelial cells. J. Clin. Invest. 92:1866-1874.
23. Corson, M.A., N.L. James, S.E. Latta, R.M. Nerem, B.C. Berk, and D.G. Harrison. 1996. Phosphorylation of endothelial nitric oxide synthase in response to fluid shear stress. Circ. Res. 79:984-991.
24. DeCaterina, R., P. Libby, H.-B. Peng, V.J. Thannickal, T.B. Rajavashisth, M.A. Gimbrone, Jr., W.-S. Shin, and J.K. Liao. 1995. Nitric oxide decreases cytokine-induced endothelial activation. J. Clin. Invest. 96:60-68.
25. Khan, B.V., D.G. Harrison, M.T. Olbrych, R.W. Alexander, and R.M. Medford. 1996. Nitric oxide regulated vascular cell adhesion molecule 1 gene expression and redox-sensitive transcriptional events in human vascular endothelial cells. Proc. Natl. Acad. Sci. USA. 93:9114-9119.
26. Ziegler, T., V. Harrison, and D. Hayoz. 1996. Synergistic effects of shear stress, cyclic stretch and pressure on ecNOS and ET-1 mRNA in endothelial cells. J. Vasc. Res. 33(Suppl. 31:)113a. (Abstr.)
27. Walpola, P.L., A.I. Gotlieb, M.I. Cybulsky, and B.L. Langille. 1995. Expression of ICAM-1 and VCAM-1 and monocyte adherence in arteries exposed to altered shear stress. Arterioscler. Thromb. Vasc. Biol. 15:2-10.
28. Nakashima, Y., A.S. Plump, E.W. Raines, J.L. Breslow, and R. Ross. 1994. ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler. Thromb. Vasc. Biol. 14:133-140.
29. Resnick, N., T. Collins, W. Atkinson, D.T. Bonthron, C.F. Dewey, Jr., and M.A. Gimbrone, Jr. 1993. Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element. Proc. Natl. Acad. Sci. USA. 90:4591-4595.
30. Khachigian, L.M., N. Resnick, M.A. Gimbrone, Jr., and T. Collins. 1995. Nuclear factor-κB interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress. J. Clin. Invest. 96:1169-1175.
31. Khachigian, L.M., K.R. Anderson, N.J. Halnon, M.A. Gimbrone, Jr., N. Resnick, and T. Collins. 1997. Egr-1 is activated in endothelial cells exposed to fluid shear-stress and interacts with a novel shear-stress response element in the PDGF A-chain promoter. Arterioscler. Thromb. Vasc. Biol. In press.
32. Shyy, J.Y.J, M.C. Lin, J.H. Han, Y.J. Lu, M. Petrime, and S. Chien. 1995. The cis-acting phorbol ester 12-O-tetradecanoylphorbol-13-acetate-responsive element is involved in shear stress-induced monocyte chemotactic protein 1 gene expression. Proc. Natl. Acad. Sci. USA. 92:8069-8073.
33. Lin, M.-C., F. Almus-Jacobs, H.-H. Chen, G.C.N. Parry, N. Mackman, J.Y.-J. Shyy, and S. Chien. 1997. Shear stress induction of the tissue factor gene. J. Clin. Invest. 99:737-744.
34. Ohno, M., J.P. Cooke, V.J. Dzau, and G.H. Gibbons. 1995. Fluid shear stress induces endothelial transforming growth factor β-1 transcription and production. Modulation by potassium channel blockade. J. Clin. Invest. 95:1363-1369.
35. Nagel, T., S.M. Wasserman, N. Resnick, J.N. Topper, M.E. Gerritsen, C.F. Dewey, Jr., and M.A. Gimbrone, Jr. 1996. Transcriptional upregulation of endothelial ICAM-1 by laminar shear stress. J. Vasc. Res. 33(Suppl. 1):71a. (Abstr.)
36. Malek, A.M., and S. Izumo. 1994. Molecular aspects of signal transduction of shear stress in the endothelial cell (editorial review). J. Hypertension. 12: 989-999.
37. Konstantopoulos, K., and L.V. McIntire. 1996. Effects of fluid dynamic forces on vascular cell adhesion. J. Clin. Invest. 98:2661-2665.