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Volumn 97, Issue 7, 1999, Pages 853-863

Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ADAPTOR PROTEIN; ISOENZYME; P21 ACTIVATED KINASE; PROTEIN DOCK; PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 0033603254     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80798-9     Document Type: Article
Times cited : (243)

References (37)
  • 1
    • 0029126514 scopus 로고
    • Analyzing protein-protein interactions using two-hybrid systems
    • Bartel, P.L., and Fields, S. (1995). Analyzing protein-protein interactions using two-hybrid systems. Methods Enzymol. 254, 241-263.
    • (1995) Methods Enzymol. , vol.254 , pp. 241-263
    • Bartel, P.L.1    Fields, S.2
  • 2
  • 3
    • 0030134625 scopus 로고    scopus 로고
    • Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
    • Brown, J.L, Stowers, L., Baer, M., Trejo, J., Coughlin, S., and Chant, J. (1996). Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway. Curr. Biol. 6, 598-605.
    • (1996) Curr. Biol. , vol.6 , pp. 598-605
    • Brown, J.L.1    Stowers, L.2    Baer, M.3    Trejo, J.4    Coughlin, S.5    Chant, J.6
  • 4
    • 0028786020 scopus 로고
    • A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases
    • Burbelo, P.D., Drechsel, D., and Hall, A. (1995). A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases. J. Biol. Chem. 270, 29071-29074.
    • (1995) J. Biol. Chem. , vol.270 , pp. 29071-29074
    • Burbelo, P.D.1    Drechsel, D.2    Hall, A.3
  • 5
    • 0030056718 scopus 로고    scopus 로고
    • A Drosophila protein-tyrosine phosphatase associates with an adaptor protein required for axonal guidance
    • Clemens, J.C., Ursuliak, Z., Clemens, K.K., Price, U.V., and Dixon, J. (1996). A Drosophila protein-tyrosine phosphatase associates with an adaptor protein required for axonal guidance. J. Biol. Chem. 271, 17002-17005.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17002-17005
    • Clemens, J.C.1    Ursuliak, Z.2    Clemens, K.K.3    Price, U.V.4    Dixon, J.5
  • 7
    • 0032561355 scopus 로고    scopus 로고
    • Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation
    • Frost, J.A., Khokhlatchev, A., Stippec, S., White, M.A., and Cobb, M.H. (1998). Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation. J. Biol. Chem. 273, 28191-28198.
    • (1998) J. Biol. Chem. , vol.273 , pp. 28191-28198
    • Frost, J.A.1    Khokhlatchev, A.2    Stippec, S.3    White, M.A.4    Cobb, M.H.5
  • 8
    • 0029830139 scopus 로고    scopus 로고
    • The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1
    • Galisteo, M.L., Chernoff, J., Su, Y.C., Skolnik, E.Y., and Schlessinger, J. (1996). The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1. J. Biol. Chem. 271, 20997-21000.
    • (1996) J. Biol. Chem. , vol.271 , pp. 20997-21000
    • Galisteo, M.L.1    Chernoff, J.2    Su, Y.C.3    Skolnik, E.Y.4    Schlessinger, J.5
  • 9
    • 0029943447 scopus 로고    scopus 로고
    • Drosophila photoreceptor axon guidance and targeting requires the Dreadlocks SH2/SH3 adaptor protein
    • Garrity, P.A., Rao, Y., Salecker, I., McGlade, J., Pawson, T., and Zipursky, S.L. (1996). Drosophila photoreceptor axon guidance and targeting requires the Dreadlocks SH2/SH3 adaptor protein. Cell 85, 639-650.
    • (1996) Cell , vol.85 , pp. 639-650
    • Garrity, P.A.1    Rao, Y.2    Salecker, I.3    McGlade, J.4    Pawson, T.5    Zipursky, S.L.6
  • 10
    • 0033119536 scopus 로고    scopus 로고
    • Retinal axon target selection in Drosophila is controlled by a receptor protein tyrosine phosphatase
    • Garrity, P.A., Lee, C.-H., Salecker, I., Robert, C.D., Zinn, K., and Zipursky, S.L. (1999). Retinal axon target selection in Drosophila is controlled by a receptor protein tyrosine phosphatase. Neuron 22, 707-717.
    • (1999) Neuron , vol.22 , pp. 707-717
    • Garrity, P.A.1    Lee, C.-H.2    Salecker, I.3    Robert, C.D.4    Zinn, K.5    Zipursky, S.L.6
  • 11
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases actin cytoskeleton
    • Hall, A. (1998). Rho GTPases actin cytoskeleton. Science 279, 509-514.
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 12
    • 0023885305 scopus 로고
    • The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
    • Hanks, S.K., Quinn, A.M., and Hunter, T. (1988). The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 247, 42-52.
    • (1988) Science , vol.247 , pp. 42-52
    • Hanks, S.K.1    Quinn, A.M.2    Hunter, T.3
  • 13
    • 0029963547 scopus 로고    scopus 로고
    • A Drosophila homolog of the Rac- And Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures
    • Harden, N., Lee, J., Loh, H.Y., Ong, Y.M., Tan, I., Leung, T., Manser, E., and L.L. (1996). A Drosophila homolog of the Rac- and Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures. Mol. Cell. Biol. 16, 1896-1908.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1896-1908
    • Harden, N.1    Lee, J.2    Loh, H.Y.3    Ong, Y.M.4    Tan, I.5    Leung, T.6    Manser, E.7    La., L.8
  • 14
    • 0029927296 scopus 로고    scopus 로고
    • Hepatocyte growth factor induces activation of Nek and phospholipase C-gamma in lung carcinoma cells
    • Kochhar, K.S., and Iyer, A.P. (1996). Hepatocyte growth factor induces activation of Nek and phospholipase C-gamma in lung carcinoma cells. Cancer Lett. 104, 163-169.
    • (1996) Cancer Lett. , vol.104 , pp. 163-169
    • Kochhar, K.S.1    Iyer, A.P.2
  • 15
    • 0030298138 scopus 로고    scopus 로고
    • Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade
    • Lamarche, N., Tapon, N., Stowers, L., Burbelo, P.D., Aspenstrom, P., Bridges, T., Chant, J., and Hall, A. (1996). Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade. Cell 87, 519-529.
    • (1996) Cell , vol.87 , pp. 519-529
    • Lamarche, N.1    Tapon, N.2    Stowers, L.3    Burbelo, P.D.4    Aspenstrom, P.5    Bridges, T.6    Chant, J.7    Hall, A.8
  • 16
    • 0032495478 scopus 로고    scopus 로고
    • Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases
    • Leeuw, T., Wu, C., Schrag, J.D., Whiteway, M., Thomas, D.Y., and Leberer, E. (1998). Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases. Nature 391, 191-195.
    • (1998) Nature , vol.391 , pp. 191-195
    • Leeuw, T.1    Wu, C.2    Schrag, J.D.3    Whiteway, M.4    Thomas, D.Y.5    Leberer, E.6
  • 17
    • 0031080595 scopus 로고    scopus 로고
    • Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nek
    • Lu, W., Katz, S., Gupta, R., and Mayer, B.J. (1997). Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nek. Curr. Biol. 7, 85-94.
    • (1997) Curr. Biol. , vol.7 , pp. 85-94
    • Lu, W.1    Katz, S.2    Gupta, R.3    Mayer, B.J.4
  • 18
    • 0028086441 scopus 로고
    • Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion
    • Luo, L., Liao, Y.J., Jan, L.Y., and Jan, Y.N. (1994). Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion. Genes Dev. 8, 1787-1802.
    • (1994) Genes Dev. , vol.8 , pp. 1787-1802
    • Luo, L.1    Liao, Y.J.2    Jan, L.Y.3    Jan, Y.N.4
  • 19
    • 0028078824 scopus 로고
    • A brain serine/threonine protein kinase activated by Cdc42 and Rac1
    • Manser, E., Leung, T., Salihuddin, H., Zhao, Z.-S., and Lim, L. (1994). A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 367, 40-46.
    • (1994) Nature , vol.367 , pp. 40-46
    • Manser, E.1    Leung, T.2    Salihuddin, H.3    Zhao, Z.-S.4    Lim, L.5
  • 20
    • 0031036626 scopus 로고    scopus 로고
    • Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes
    • Manser, E., Huang, H.Y., Loo, T.H., Chen, X.Q., Dong, J.M., Leung, T., and Lim, L. (1997). Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes. Mol. Cell. Biol. 17, 1129-1143.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1129-1143
    • Manser, E.1    Huang, H.Y.2    Loo, T.H.3    Chen, X.Q.4    Dong, J.M.5    Leung, T.6    Lim, L.7
  • 21
  • 22
    • 0032213509 scopus 로고    scopus 로고
    • The Nek SH2/SH3 adaptor protein: A regulator of multiple intracellular signal transduction events
    • McCarty, J.H. (1998). The Nek SH2/SH3 adaptor protein: a regulator of multiple intracellular signal transduction events. BioEssays 20, 913-921.
    • (1998) BioEssays , vol.20 , pp. 913-921
    • McCarty, J.H.1
  • 23
    • 0032488053 scopus 로고    scopus 로고
    • A protein related to p21-activated kinase (PAK) that is involved in neurogenesis in the Drosophila adult central nervous system
    • Melzig, J., Rein, K.H., Schafer, U., Pfister, H., Jackle, H., Heisenberg, M., and Raabe, T. (1998). A protein related to p21-activated kinase (PAK) that is involved in neurogenesis in the Drosophila adult central nervous system. Curr. Biol. 8, 1223-1226.
    • (1998) Curr. Biol. , vol.8 , pp. 1223-1226
    • Melzig, J.1    Rein, K.H.2    Schafer, U.3    Pfister, H.4    Jackle, H.5    Heisenberg, M.6    Raabe, T.7
  • 25
    • 0030049170 scopus 로고    scopus 로고
    • Actin-based cell motility and cell locomotion
    • Mitchison, T.J., and Cramer, L.P. (1996). Actin-based cell motility and cell locomotion. Cell 84, 371-379.
    • (1996) Cell , vol.84 , pp. 371-379
    • Mitchison, T.J.1    Cramer, L.P.2
  • 26
    • 0032479975 scopus 로고    scopus 로고
    • PAK promotes morphological changes by acting upstream of Rac
    • Obermeier, A., Ahmed, S., Manser, E., Yen, S., Hall, C., and Lim, L. (1998). PAK promotes morphological changes by acting upstream of Rac. EMBO J. 17, 4328-4339.
    • (1998) EMBO J. , vol.17 , pp. 4328-4339
    • Obermeier, A.1    Ahmed, S.2    Manser, E.3    Yen, S.4    Hall, C.5    Lim, L.6
  • 27
    • 0032478083 scopus 로고    scopus 로고
    • Domain requirements for the Dock adaptor protein in growth-cone signaling
    • Rao, Y., and Zipursky, S.L. (1998). Domain requirements for the Dock adaptor protein in growth-cone signaling. Proc. Natl. Acad. Sci. USA 95, 2077-2082.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 2077-2082
    • Rao, Y.1    Zipursky, S.L.2
  • 28
    • 0032567079 scopus 로고    scopus 로고
    • Hedgehog and Spitz: Making a match between photoreceptor axons and their targets
    • Salecker, I., Clandinin, T.R., and Zipursky, S.L. (1998). Hedgehog and Spitz: making a match between photoreceptor axons and their targets. Cell 95, 587-590.
    • (1998) Cell , vol.95 , pp. 587-590
    • Salecker, I.1    Clandinin, T.R.2    Zipursky, S.L.3
  • 29
    • 0031105660 scopus 로고    scopus 로고
    • Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells
    • Sells, M.A., Knaus, U.G., Bagrodia, S., Ambrose, D.M., Bokoch, G.M., and Chernoff, J. (1996). Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells. Curr. Biol. 7, 202-210.
    • (1996) Curr. Biol. , vol.7 , pp. 202-210
    • Sells, M.A.1    Knaus, U.G.2    Bagrodia, S.3    Ambrose, D.M.4    Bokoch, G.M.5    Chernoff, J.6
  • 30
    • 0022134524 scopus 로고
    • The nucleotide sequence and the tissue-specific expression of Drosophila c-src
    • Simon, M.A., Drees, B., Kornberg, T., and Bishop, J.M. (1985). The nucleotide sequence and the tissue-specific expression of Drosophila c-src. Cell 42, 831-840.
    • (1985) Cell , vol.42 , pp. 831-840
    • Simon, M.A.1    Drees, B.2    Kornberg, T.3    Bishop, J.M.4
  • 31
    • 0031893255 scopus 로고    scopus 로고
    • Nek recruitment to Eph receptor, EphB1/ELK, couples ligand activation to c-Jun kinase
    • Stein, E., Huynh-Do, U., Lane, A.A., Cerretti, D.P., and Daniel, T.O. (1998). Nek recruitment to Eph receptor, EphB1/ELK, couples ligand activation to c-Jun kinase. J. Biol. Chem. 273, 1303-1308.
    • (1998) J. Biol. Chem. , vol.273 , pp. 1303-1308
    • Stein, E.1    Huynh-Do, U.2    Lane, A.A.3    Cerretti, D.P.4    Daniel, T.O.5
  • 32
    • 0031967521 scopus 로고    scopus 로고
    • An emerging link between cytoskeletal dynamics and cell adhesion molecules in growth cone guidance
    • Suter, D.M., and Forscher, P. (1998). An emerging link between cytoskeletal dynamics and cell adhesion molecules in growth cone guidance. Curr. Opin. Neurobiol. 8, 106-116.
    • (1998) Curr. Opin. Neurobiol. , vol.8 , pp. 106-116
    • Suter, D.M.1    Forscher, P.2
  • 33
    • 0029959555 scopus 로고    scopus 로고
    • The molecular biology of axon guidance
    • Tessier-Lavigne, M., and Goodman, C.S. (1996). The molecular biology of axon guidance. Science 274, 1123-1133.
    • (1996) Science , vol.274 , pp. 1123-1133
    • Tessier-Lavigne, M.1    Goodman, C.S.2
  • 34
    • 0032524324 scopus 로고    scopus 로고
    • Genetic analysis of the mechanisms controlling target selection: Complementary and combinatorial function of netrins, semaphorins and IgCAMs
    • Winberg, M.L., Mitchell, K.J., and Goodman, C.S. (1998). Genetic analysis of the mechanisms controlling target selection: complementary and combinatorial function of netrins, semaphorins and IgCAMs. Cell 93, 581-591.
    • (1998) Cell , vol.93 , pp. 581-591
    • Winberg, M.L.1    Mitchell, K.J.2    Goodman, C.S.3
  • 35
    • 0032188987 scopus 로고    scopus 로고
    • A NckPak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK
    • Yablonski, D., Kane, L.P., Qian, D., and Weiss, A. (1998). A NckPak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK. EMBO J. 17, 5647-5657.
    • (1998) EMBO J. , vol.17 , pp. 5647-5657
    • Yablonski, D.1    Kane, L.P.2    Qian, D.3    Weiss, A.4
  • 36
    • 0031948850 scopus 로고    scopus 로고
    • A conserved negative regulatory region in alphaPAK: Inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1
    • Zhao, Z.S., Manser, E., Chen, X.Q., Chong, C., Leung, T., and Lim, L. (1998). A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1. Mol. Cell. Biol. 18, 2153-2163.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2153-2163
    • Zhao, Z.S.1    Manser, E.2    Chen, X.Q.3    Chong, C.4    Leung, T.5    Lim, L.6
  • 37
    • 0030866898 scopus 로고    scopus 로고
    • Role of a new Rho family member in cell migration and axon guidance in C. elegans
    • Zipkin, I.D., Kindt, R.M., and Kenyon, C.J. (1997). Role of a new Rho family member in cell migration and axon guidance in C. elegans. Cell 90, 883-894.
    • (1997) Cell , vol.90 , pp. 883-894
    • Zipkin, I.D.1    Kindt, R.M.2    Kenyon, C.J.3


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