Phosphorothioate oligodeoxyribonucleotides inhibit ribonuclease L thereby disabling a mechanism of interferon action

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 6, 1999, Pages 891-894

  Player, Mark R ^a,b   Torrence, Paul F ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b JOHNSON AND JOHNSON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; RIBONUCLEASE;

ARTICLE; CHIMERA; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; NUCLEOTIDE SEQUENCE; STRUCTURE ACTIVITY RELATION;

ENDORIBONUCLEASES; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; OLIGODEOXYRIBONUCLEOTIDES; THIONUCLEOTIDES;

EID: 0033594198     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00099-2     Document Type: Article

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