2',5'-Oligoadenylate-peptide nucleic acids (2-5A-PNAs) activate RNase L

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 3, 1999, Pages 449-455

  Verheijen, Jeroen C ^a   Van Der Marel, Gijsbert A ^a   Van Boom, Jacques H ^a   Bayly, Suzanne F ^b   Player, Mark R ^b   Torrence, Paul F ^b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

2 5A; Antisense; Chemotherapy; Nucleic acids; Peptides and polypeptides; PNA; RNA

Indexed keywords

2',5' OLIGOADENYLIC ACID; ANTISENSE OLIGONUCLEOTIDE; NUCLEIC ACID; RIBONUCLEASE;

ARTICLE; CATALYSIS; CHIMERA; DRUG CONJUGATION; DRUG SYNTHESIS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NUCLEIC ACID SYNTHESIS; RNA CLEAVAGE; SOLID PHASE EXTRACTION;

ADENINE NUCLEOTIDES; CELL LINE; ENDORIBONUCLEASES; ENZYME ACTIVATION; HUMANS; HYDROLYSIS; OLIGORIBONUCLEOTIDES; PEPTIDE NUCLEIC ACIDS; RADIOLIGAND ASSAY; RECOMBINANT PROTEINS;

EID: 0033018595     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00258-2     Document Type: Article

References (32)

1. Stephenson, M. L.; Zamecnik, P. C. Proc. Natl. Acad. Sci. USA 1978, 75, 285.
2. Zamecnik, P. C.; Stephenson, M. L. Proc. Natl. Acad. Sci. USA 1978, 75, 280.
3. Stein, C. A.; Cheng, Y.-C. Science 1993, 261, 1004.
4. Milligan, J. F.; Matteucci, M. D.; Martin, J. C. J. Med. Chem. 1993, 36, 1923.
5. de Mesmaeker, A.; Haner, R.; Martin, P.; Moser, H. E. Acc. Chem. Res. 1995, 28, 366.
6. Nielsen, P. E.; Egholm, M.; Berg, R. H.; Buchardt, O. Science 1991, 254, 1497.
7. Demidov, V. V.; Potaman, V. N.; Frank-Kamenetskii, M. D.; Egholm, M.; Buchardt, O.; Sonnichsen, S. H.; Nielsen, P. E. Biochem. Pharmacol. 1994, 48, 1310.
8. Knudsen, H.; Nielsen, P. E. Nucleic Acids Res. 1996, 24, 494.
9. Hanvey, J. C.; Peffer, N. J.; Bisi, J. E.; Thomson, S. A.; Cadilla, R.; Josey, J. A.; Ricca, D. J.; Hassman, C. F.; Bonham, M. A.; Au, K. G.; Carter, S. G.; Bruckenstein, D. A.; Boyd, A. L.; Noble, S. A.; Babiss, L. E. Science 1992, 258, 1481.
10. Torrence, P. F.; Maitra, R. K.; Lesiak, K.; Khamnei, S.; Zhou. A.; Silverman, R. H. Proc. Natl. Acad. Sci. USA 1993, 90, 1300.
11. Torrence, P. F.; Xiao, W.; Li, G.; Lesiak, K.; Khamnei, S.; Maran, A.; Maitra, R.; Dong, B.; Silverman, R. H. In Carbohydrate Modifications in Antisense Research; Sanghvi, Y. S.; Cook, P. D., Eds.; American Chemical Society: Washington, DC, 1994; pp 119-132.
12. Torrence, P. F.; Xiao, W.; Li, G.; Cramer, H.; Player, M. R.; Silverman, R. H. Antisense Nucleic Acid Drug Dev. 1997, 7, 203.
13. Maran, A.; Maitra, R. K.; Kumar, A.; Dong, B.; Xiao, W.; Li, G.; Williams, B. R. G.; Torrence, P. F.; Silverman, R. H. Science 1994, 265, 789.
14. Maitra, R. K.; Li, G.; Xiao, W.; Dong, B.; Torrence, P. F.; Silverman, R. H.; J. Biol. Chem. 1995, 270, 15071.
15. Cirino, N. M.; Li, G.; Xiao, W.; Torrence, P. F.; Silverman, R. H. Proc. Natl. Acad. Sci. USA 1997, 94, 1937.
16. Player, M. R.; Barnard, D. L.; Torrence, P. F. Proc. Natl. Acad. Sci. USA 1998, 95, 8874.
17. Player, M. R.; Maitra, R. K.; Silverman, R. H.; Torrence, P. F. Antiviral Chem. Chemother. 1998, 9, 225.
18. Player, M. R.; Torrence, P. F. Pharmacol. Ther. 1998, 78, 55.
19. Petersen, K. H.; Jensen, D. K.; Egholm, M.; Nielsen, P. E.; Buchardt, O. Bioorg. Med. Chem. Lett. 1995, 5, 1119.
20. Uhlmann, E.; Will, D. W.; Breipohl, G.; Langner, D.; Ryte, A. Angew. Chem., Int. Ed. Engl. 1996, 35, 2632.
21. van der Laan, A. C.; Brill, R.; Kruimelis, R. G.; Kuyl-Yehskiely, E.; van Boom, J. H.; Andrus, A.; Vinayak, R. Tetrahedron Lett. 1997, 38, 2249.
22. Will, D. W.; Breipohl, G.; Langner, D.; Knolle, J.; Uhlmann, E. Tetrahedron 1995, 51, 12069.
23. Fillipov, D. Ph.D. Thesis, Leiden University, 1998.
24. Lesiak, K.; Khamnei, S.; Torrence, P. F. Bioconjugate Chem. 1993, 4, 467.
25. Carroll, S. S.; Chen, E.; Viscount, T.; Geib, J.; Sardana, M. K.; Gehman, J.; Kuo, L. C. J. Biol. Chem. 1996, 271, 4988.
26. Xiao, W.; Li, G.; Player, M. R.; Maitra, R. K.; Waller, C. F.; Silverman, R. H.; Torrence, P. F. J. Med. Chem. 1998, 41, 1531.
27. Carroll, S. S.; Cole, J. L.; Viscount, T.; Geib, J.; Gehman, J.; Kuo, L. C. J. Biol. Chem. 1997, 272, 19193.
28. Hyrup, B.; Nielsen, P. E. Bioorg. Med. Chem. 1996, 4, 5.
29. Simmons, C. G.; Pitts, A. E.; Mayfield, L. D.; Shay, J. W.; Corey, D. R. Bioorg. Med. Chem. Lett. 1997, 7, 3001.
30. Player, M. R.; Wondrak, E. M.; Bayly, S. F.; Torrence, P. F. Methods: A companion to Methods in Enzymology 1998, 15, 243.
31. Silverman, R. H.; Krause, D. In Lymphokines and Interferons: A Practical Approach; Clemens, M. J.; Morris, A. G.; Gearing, A. J. H., Eds.; IRL Press: Oxford, 1987; pp 149-193.
32. Kovacs, T.; Pabuccuoglu, A.; Lesiak, K.; Torrence, P. F. Bioorg. Chem. 1993, 21, 192.