Nuclease-resistant composite 2',5'-oligoadenylate-3',5'- oligonucleotides for the targeted destruction of RNA: 2-5A-iso-antisense

Journal of Medicinal Chemistry

Volumn 41, Issue 9, 1998, Pages 1531-1539

  Xiao, Wei ^c   Li, Guiying ^d   Player, Mark R ^f   Maitra, Ratan K ^a   Waller, Cornelius F ^a,e   Silverman, Robert H ^a   Torrence, Paul F ^b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c CACI INTERNATIONAL INC   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^e UNIVERSITY OF FREIBURG   (Germany)

^f NONE

Author keywords

[No Author keywords available]

Indexed keywords

2',5' OLIGOADENYLIC ACID; 2-5A ANTISENSE OLIGONUCLEOTIDE; 2-5A ISO ANTISENSE OLIGONUCLEOTIDE; COMPLEMENTARY DNA; EXONUCLEASE; NUCLEIC ACID; OLIGONUCLEOTIDE; PHOSPHODIESTERASE; SNAKE VENOM; UNCLASSIFIED DRUG;

ARTICLE; CHIMERA; DNA MODIFICATION; ENZYME ACTIVITY; RNA BINDING; RNA DEGRADATION; RNA STRUCTURE;

DNA, COMPLEMENTARY; EIF-2 KINASE; ENDORIBONUCLEASES; FUSION PROTEINS, BCR-ABL; HUMANS; OLIGONUCLEOTIDES, ANTISENSE; OLIGORIBONUCLEOTIDES; PHOSPHODIESTERASE I; PHOSPHORIC DIESTER HYDROLASES; RNA; RNA, NEOPLASM;

EID: 0032560140     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970841p     Document Type: Article

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