A complex ligase ribozyme evolved in vitro from a group I ribozyme domain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 26, 1999, Pages 14712-14717

  Jaeger, Luc ^a,b   Wright, Martin C ^b,c   Joyce, Gerald F ^b  

^a CNRS   (France)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c Phylos Inc   (United States)

Author keywords

In vitro evolution; In vitro selection; RNA enzyme; RNA structure

Indexed keywords

LIGASE; RIBOZYME;

ALTERNATIVE RNA SPLICING; ARTICLE; CATALYSIS; COMPLEX FORMATION; DNA LIBRARY; DNA RNA HYBRIDIZATION; EVOLUTION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; RNA STRUCTURE;

NASA DISCIPLINE EXOBIOLOGY; NON-NASA CENTER;

ANIMALS; BASE SEQUENCE; CATALYSIS; CATALYTIC DOMAIN; DIRECTED MOLECULAR EVOLUTION; GENE LIBRARY; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; POLYNUCLEOTIDE LIGASES; RNA, CATALYTIC; TETRAHYMENA;

EID: 0033592981     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.26.14712     Document Type: Article

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