Mutations in the nucleotide-binding sites of P-Glycporotein that affect substrate specificity modulate substrate-induced adenosine Triphosphatase activity

Biochemistry

Volumn 37, Issue 25, 1998, Pages 9073-9082

  Beaudet, Lucille ^a   Urbatsch, Ina L ^a   Gros, Philippe ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLYCOPROTEIN P; VALINOMYCIN; VERAPAMIL;

ARTICLE; ENDOMYCETALES; ENZYME ACTIVITY; ENZYME MODIFICATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; AZIDES; BINDING SITES; IODINE RADIOISOTOPES; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; P-GLYCOPROTEIN; P-GLYCOPROTEINS; PHOTOAFFINITY LABELS; PICHIA; PRAZOSIN; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI; MAMMALIA; PICHIA PASTORIS; SACCHAROMYCETALES;

EID: 0032560635     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972656j     Document Type: Article

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