Activation of a cAMP pathway and induction of melanogenesis correlate with association of p16(INK4) and p27(KIP1) to CDKs, loss of E2F-binding activity, and premature senescence of human melanocytes

Experimental Cell Research

Volumn 253, Issue 2, 1999, Pages 561-572

  Haddad, Maher M ^a   Xu, Weidong ^a   Schwahn, Denise J ^a   Liao, Fu ^a   Medrano, Estela E ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

E2F; Melanoma; Microphthalmia; P16(INK4); P27(KIP1); Senescence

Indexed keywords

ALPHA INTERMEDIN; CYCLIC AMP; CYCLIN D1; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; FORSKOLIN; MELANIN; PROTEIN P16; PROTEIN P27; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F;

ARTICLE; CANCER CELL; CANCER INHIBITION; CARCINOGENESIS; CELL AGING; CELL DIFFERENTIATION; CELL IMMORTALIZATION; CONTROLLED STUDY; DNA BINDING; FETUS; HUMAN; HUMAN CELL; MELANOCYTE; MELANOGENESIS; MELANOMA; MICROPHTHALMIA; NEWBORN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SENESCENCE;

EID: 0033572879     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1999.4688     Document Type: Article

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