Cooperative interactions between paired domain and homeodomain

Development

Volumn 122, Issue 9, 1996, Pages 2639-2650

  Jun, Susie ^a   Desplan, Claude ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Cooperativity; DNA binding; Homeodomain; Paired domain; Pax genes

Indexed keywords

HELIX LOOP HELIX PROTEIN; HOMEODOMAIN PROTEIN; REGULATOR PROTEIN;

ARTICLE; COOPERATION; DNA SEQUENCE; MOLECULAR MODEL; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

ANIMALS; BASE SEQUENCE; BINDING SITES; CLONING, MOLECULAR; CONSENSUS SEQUENCE; DNA; DNA-BINDING PROTEINS; DROSOPHILA; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE LIBRARY; GENES, INSECT; HELIX-TURN-HELIX MOTIFS; HOMEODOMAIN PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS;

EUKARYOTA;

EID: 0029837282     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Baldwin, C. T., Hoth, C. F., Amos, J. A., da Silva, E. and Milunsky, A. (1992). An exonic mutation in the HuP2 paired domain gene causes Waardenburg's syndrome. Nature 355, 637-638.
2. Bertuccioli, C., Fasano, L., Jun, S., Wang, S., Sheng, G. and Desplan, C. (1996). In vivo requirement for the paired domain and homeodomain of the paired segmentation gene product. Development 122, 2673-2685.
3. Bopp, D., Burri, M., Baumgartner, S., Frigerio, G. and Noll, M. (1986). Conservation of a large protein domain in the segmentation gene paired and in functionally related genes in Drosophila. Cell 47, 1033-1049.
4. Cai, J., Lan, Y., Appel, L. F. and Weir, M. (1994). Dissection of the Drosophila Paired protein: Functional requirements for conserved motifs. Mech. Dev. 47, 139-150.
5. Chalepakis, G., Fritsch, R., Fickenscher, H., Deutsch, U., Goulding, M. and Gruss, P. (1991). The molecular basis of the undulated/Pax-1 mutation. Cell 66, 873-884.
6. Chalepakis, G., Stoykova, A., Wijnholds, J., Tremblay, P. and Gruss, P. (1993). Pax: gene regulators in the developing nervous system. J. Neurobiol. 24, 1367-1384.
7. Chan, S. K., Jaffe, L., Capovilla, M., Botas, J. and Mann, R. S. (1994). The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein. Cell 78, 603-615.
8. Chang, C., Shen, W., Rozenfeld, S., Lawrence, H. J., Largman, C. and Cleary, M. L. (1995). Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins. Genes Dev. 9, 663-674.
9. Chisholm, A. D. and Horvitz, H. R. (1995). Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3. Nature 376, 52-55.
10. Cvekl, A., Sax, C. M., Li, X., McDermott, J. B. and Piatigorsky, J. (1995). Pax-6 and lens-specific transcription of the chicken delta 1-crystallin gene. Proc. Natl. Acad. Sci. USA 92, 4681-4685.
11. Czerny, T. and Busslinger, M. (1995). DNA-binding and transactivation properties of Pax-6: three amino acids in the Paired Domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5). Molec. Cell. Biol. 15, 2858-2871.
12. Czerny, T., Schaffner, G. and Busslinger, M. (1993). DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site. Genes Dev. 7, 2048-2061.
13. Ellenberger, T. E., Brandl, C. J., Struhl, K. and Harrison, S. C. (1992). The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complex. Cell 71, 1223-1237.
14. Epstein, D. J., Malo, D., Vekemans, M. and Gros, P. (1991a). Molecular characterization of a deletion encompassing the splotch mutation on mouse chromosome 1. Genomics 10, 89-93.
15. Epstein, D. J., Vekemans, M. and Gros, P. (1991b). splotch (Sp2H), a Mutation Affecting Development of the Mouse Neural Tube, Shows a Deletion within the Paired Homeodomain of Pax-3. Cell 61, 767-774.
16. Epstein, J., Cai, J., Glaser, T., Jepeal, L. and Maas, R. (1994a). Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes. J. Biol. Chem. 269, 8355-8361.
17. Epstein, J. A., Glaser, T., Cai, J., Jepeal, L., Walton, D. S. and Maas, R. L. (1994b). Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing. Genes Dev. 8, 2022-2034.
18. Fortini, M. E. and Rubin, G. M. (1990). Analysis of cis-acting requirements of the Rh3 and Rh4 genes reveals a bipartite organization to rhodopsin promoters in Drosophila melanogaster. Genes Dev. 4, 444-463.
19. Frigerio, G., Burri, M., Bopp, D., Baumgartner, S. and Noll, M. (1986). Structure of the segmentation of gene paired and the Drosophila PRD gene set as part of a gene network. Cell 47, 735-746.
20. Fujioka, M., Miskiewicz, P., Raj, L., Gulledge, A., Weir M. and Goto, T. (1996). Drosophila paired regulates late even-skipped expression through a composite binding site for the paired domain and the homeodomain. Development 122 (9), 000-000.
21. Glaser, T., Walton, D. S. and Maas, R. L. (1992). Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene. Nature Genetics 2, 232-239.
22. Goulding, M., Sterrer, S., Fleming, J., Balling, R., Nadeau, J., Moore, K. J., Brown, S. D., Steel, K. P. and Gruss, P. (1993). Analysis of the Pax-3 gene in the mouse mutant splotch. Genomics 17, 355-363.
23. Halder, G., Callaerts, P. and Gehring, W. J. (1995). Induction of Ectopic Eyes by Targeted Expression of the eyeless Gene in Drosophila. Science 267, 1788-1792.
24. Hanson, I. M., Fletcher, J. M., Jordan, T., Brown, A., Taylor, D., Adams, R. J., Punnett, H. H. and van Heyningen, H. (1994). Mutations at the PAX6 locus are found in heterogeneous anterior segment malformations including Peters' anomaly. Nature Genetics 6, 168-173.
25. Hill, R. E., Favor, J., Hogan, B. L. M., Ton, C. C. T., Saunders, G. F., Hanson, I. M., Prosser, J., Jordan, T., Hastie, N. D. and van Heyningen, H. (1991). Mouse Small eye results from mutations in a paired-like homeobox-containing gene. Nature 354, 522-525.
26. Jordan, T., Hanson, I., Zaletayev, D., Hodgson, S., Prosser, J., Seawright, A., Hastie, N. and van Heyningen, H. (1992). The human PAX6 gene is mutated in two patients with aniridia. Nature Genetics 1, 328-332.
27. Kilchherr, F., Baumgartern, S., Bopp, D., Frei, E. and Noll, A. M. (1986). Isolation of the paired gene of Drosophila and its spatial expression during early embryogenesis. Nature 321, 493-499.
28. Klemm, J. D., Rould, M. A., Aurora, R., Herr, W. and Pabo, C. O. (1994). Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules. Cell 77, 21-32.
29. Luisi, B. F., Xu, W. X., Otwinowski, Z., Freedman, L. P., Yamamoto, K. R. and Sigler, P. B. (1991). Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA. Nature 352, 497-505.
30. Maulbecker, C. C. and Gruss P. (1993). The oncogenic potential of Pax genes. EMBO J. 12, 2361-2367.
31. Miller, J., McLachlan, A. D. and Klug, A. (1985). Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes. EMBO J. 4, 1609-1514.
32. Miskiewicz, P., Morrissey, D., Lan, Y., Raj, L., Kessler, S., Fujioka, M., Goto, T. and Weir, M. (1996). Both the paired domain and homeodomain are required for in vivo function of Drosophila Paired. Development 122, 2709-2718.
33. Mismer, D. and Rubin, G. M. (1989). Definition of cis-acting elements regulating expression of the Drosophila melanogaster ninaE opsin gene by oligonucleotide-directed mutagenesis. Genetics 121, 77-87.
34. Morell, R., Friedman, T. B., Moeljopawiro, S., Hartono, Soewito and Asher, J. J. (1992). A frameshift mutation in the HuP2 paired domain of the probable human homolog of murine Pax-3 is responsible for Waardenburg syndrome type 1in an Indonesian family. Human Molec. Genet. 1, 243-247.
35. Noll, M. (1993). Evolution and role of Pax genes. Curr. Opin. Genet. Dev. 3, 595-605.
36. Pavletich, N. P. and Pabo, C. O. (1993). Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers. Science 261, 1701-1707.
37. Quiring, R., Walldorf, U., Kloter, U. and Gehring, W. J. (1994). Homology of the eyeless Gene of Drosophila to the Small eye gene in mice and Aniridia in humans. Science 265, 785-789.
38. Rebar, E. J. and Pabo, C. O. (1994). Zinc finger phage: affinity selection of fingers with new DNA-binding specificities. Science 263, 671-673.
39. Richardson, J., Cvekl, A. and Wistow, G. (1995). Pax-6 is essential for lens-specific expression of zeta-crystallin. Proc. Natl. Acad. Sci. USA 92, 4676-4680.
40. Stapleton, P., Weith, A., Urbanek, P., Kozmik, Z. and Busslinger, M. (1993). Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9. Nature Genetics 3, 292-298.
41. Strachan, T. and Read, A. P. (1994). Pax genes. Curr. Opin. Genet. Dev. 4, 427-438.
42. Tassabehji, M., Read, A. P., Newton, V. E., Harris, R., Balling, R., Gruss, P. and Strachan, T. (1992). Waardenburg's syndrome patients have mutations in the human homologue of the Pax-3 paired box gene. Nature 355, 635-636.
43. Treisman, J., Gonczy, P., Vashishtha, M., Harris, E. and Desplan, C. (1989). A single amino acid can determine the DNA binding specificity of homeodomain proteins. Cell 59, 553-562.
44. Treisman, J., Harris, E. and Desplan, C. (1991). The Paired Box encodes a second DNA-binding domain in the Paired homeodomain protein. Genes Dev. 5, 594-604.
45. Tsukamoto, K., Nakamura, Y. and Niikawa, N. (1994). Isolation of two isoforms of the PAX3 gene transcripts and their tissue-specific alternative expression in human adult tissues. Human Genet. 93, 270-274.
46. van Dijk, M. A. and Murre, C. (1994). Extradenticle raises the DNA binding specificity of homeotic selector gene products. Cell 78, 617-624.
47. Voronova, A. and Baltimore, D. (1990). Mutations that disrupt DNA binding and dimer formation in the E47 helix-loop-helix protein map to distinct domains. Proc. Natl. Acad. Sci. USA 87, 4722-4726.
48. Wallin, J., Mizutani, Y., Imai, K., Miyashita, N., Moriwaki, K., Taniguchi, M., Koseki, H. and Balling, R. (1993). A new Pax gene, Pax-9, maps to mouse chromosome 12. Mammalian Genome 4, 354-358.
49. Walther, C., Guenet, J. L., Simon, D., Deutsch, U., Jostes, B., Goulding, M. D., Plachov, D., Balling, R. and Gruss, P. (1991). Pax: a murine multigene family of paired box-containing genes. Genomics 11, 424-434.
50. Wilson, D., Sheng, G., Lecuit, T., Dostatni, N. and Desplan, C. (1993). Cooperative dimerization of paired class homeodomains on DNA. Genes Dev. 7, 2120-2134.
51. Wilson, D. S. and Desplan, C. (1995). Homeodomain Proteins: Cooperating to be different. Current Biol. 5, 32-34.
52. Wilson, D. S., Guenther, B., Desplan, C. and Kuriyan, J. (1995). High resolution crystal structure of a Paired (Pax) class cooperative homeodomain dimer on DNA. Cell 82, 709-719
53. Xu, W., Rould, M., Jun, S., Desplan, C. and Pabo, C. (1995). Crystal structure of a paired domain-DNA complex at 2.5A resolution reveals structural basis for Pax developmental mutations. Cell 80, 639-650.
54. Zhang, Y. and Emmons, S. W. (1995). Specification of sense-organ identity by a Caenorhabditis elegans Pax-6 homologue. Nature 376, 55-59.