메뉴 건너뛰기




Volumn 18, Issue 9, 1998, Pages 5579-5586

Dual roles for Pax-6: A transcriptional repressor of lens fiber cell- specific β-crystallin genes

Author keywords

[No Author keywords available]

Indexed keywords

BETA CRYSTALLIN; CHLORAMPHENICOL ACETYLTRANSFERASE; DEOXYRIBONUCLEASE;

EID: 0031840442     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.18.9.5579     Document Type: Article
Times cited : (116)

References (50)
  • 3
    • 0023947899 scopus 로고
    • Evidence for positive and negative regulation in the promoter of the chicken delta 1-crystallin gene
    • Borras, T., C. A. Peterson, and J. Piatigorsky. 1988. Evidence for positive and negative regulation in the promoter of the chicken delta 1-crystallin gene. Dev. Biol. 127:209-219.
    • (1988) Dev. Biol. , vol.127 , pp. 209-219
    • Borras, T.1    Peterson, C.A.2    Piatigorsky, J.3
  • 4
    • 0023705534 scopus 로고
    • Ontogeny of βB1-crystallin polypeptides during chicken lens development
    • Brahma, S. K.1988. Ontogeny of βB1-crystallin polypeptides during chicken lens development. Exp. Eye Res. 47:507-519.
    • (1988) Exp. Eye Res. , vol.47 , pp. 507-519
    • Brahma, S.K.1
  • 5
    • 0028587375 scopus 로고
    • Pax-3 contains domains for transcription activation and transcription inhibition
    • Chalepakis, G., F. S. Jones, G. M. Edelman, and P. Gruss. 1994. Pax-3 contains domains for transcription activation and transcription inhibition. Proc. Natl. Acad. Sci. USA 91:12745-12749.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12745-12749
    • Chalepakis, G.1    Jones, F.S.2    Edelman, G.M.3    Gruss, P.4
  • 6
    • 0029736446 scopus 로고    scopus 로고
    • Genetics of aniridia and anterior segment dysgenesis
    • Churchill, A., and A. Booth. 1996. Genetics of aniridia and anterior segment dysgenesis. Br. J. Ophthalmol. 80:669-673.
    • (1996) Br. J. Ophthalmol. , vol.80 , pp. 669-673
    • Churchill, A.1    Booth, A.2
  • 7
    • 0027983038 scopus 로고
    • Repression versus activation in the control of gene transcription
    • Cowell, I. G. 1994. Repression versus activation in the control of gene transcription. Trends Biochem. Sci. 19:38-42.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 38-42
    • Cowell, I.G.1
  • 8
    • 0027999510 scopus 로고
    • A complex array of positive and negative elements regulates the chicken αA-crystallin gene: Involvement of Pax-6, USF, CREB and/or CREM, and AP-1 proteins
    • Cvekl, A., C. M. Sax, E. H. Bresnick, and J. Piatigorsky. 1994. A complex array of positive and negative elements regulates the chicken αA-crystallin gene: involvement of Pax-6, USF, CREB and/or CREM, and AP-1 proteins. Mol. Cell. Biol. 14:7363-7376.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7363-7376
    • Cvekl, A.1    Sax, C.M.2    Bresnick, E.H.3    Piatigorsky, J.4
  • 9
    • 0028869811 scopus 로고
    • Transcriptional activation of the mouse αA-crystallin gene: Activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6 binding site
    • Cvekl, A., F. Kashanchi, C. M. Sax, J. N. Brady, and J. Piatigorsky. 1995. Transcriptional activation of the mouse αA-crystallin gene: activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6 binding site. Mol. Cell. Biol. 15:563-660.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 563-660
    • Cvekl, A.1    Kashanchi, F.2    Sax, C.M.3    Brady, J.N.4    Piatigorsky, J.5
  • 11
    • 0030219742 scopus 로고    scopus 로고
    • Lens development and crystallin gene expression: Many roles for Pax-6
    • Cvekl, A., and J. Piatigorsky. 1996. Lens development and crystallin gene expression: many roles for Pax-6. Bioessays 18:621-630.
    • (1996) Bioessays , vol.18 , pp. 621-630
    • Cvekl, A.1    Piatigorsky, J.2
  • 12
    • 3542991688 scopus 로고    scopus 로고
    • Submitted for publication
    • Cvekl, A., et al. Submitted for publication.
    • Cvekl, A.1
  • 13
    • 0027426925 scopus 로고
    • DNA sequence recognition by Pax proteins: Bipartite structure of the paired domain and its binding site
    • Czerny, T., G. Schaffner, and M. Busslinger. 1993. DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site. Genes Dev. 7:2048-2061.
    • (1993) Genes Dev. , vol.7 , pp. 2048-2061
    • Czerny, T.1    Schaffner, G.2    Busslinger, M.3
  • 14
    • 0028918392 scopus 로고
    • DNA-binding and transactivation properties of Pax-6: Three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5)
    • Czerny, T., and M. Busslinger. 1995. DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5). Mol. Cell. Biol. 15:2858-2871.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2858-2871
    • Czerny, T.1    Busslinger, M.2
  • 15
    • 0029738393 scopus 로고    scopus 로고
    • Role of Olf-1 and Pax-6 transcription factors in neurodevelopment
    • Davis, J. A., and R. R. Reed. 1996. Role of Olf-1 and Pax-6 transcription factors in neurodevelopment. J. Neurosci. 16:5082-5094.
    • (1996) J. Neurosci. , vol.16 , pp. 5082-5094
    • Davis, J.A.1    Reed, R.R.2
  • 16
    • 0029874066 scopus 로고    scopus 로고
    • C-terminal activating and inhibitory domains determine the transactivation potential of BSAP (Pax-5), Pax-2 and Pax-8
    • Dorfler, P., and M. Busslinger. 1996. C-terminal activating and inhibitory domains determine the transactivation potential of BSAP (Pax-5), Pax-2 and Pax-8. EMBO J. 15:1971-1982.
    • (1996) EMBO J. , vol.15 , pp. 1971-1982
    • Dorfler, P.1    Busslinger, M.2
  • 17
    • 0028987659 scopus 로고
    • Chicken βB1-crystallin: Gene sequence and evidence for functional conservation of promoter activity between chicken and mouse
    • Duncan, M. K., H. J. Roth, M. Thompson, M. Kantorow, and J. Piatigorsky. 1995. Chicken βB1-crystallin: gene sequence and evidence for functional conservation of promoter activity between chicken and mouse. Biochim. Biophys. Acta 1261:68-76.
    • (1995) Biochim. Biophys. Acta , vol.1261 , pp. 68-76
    • Duncan, M.K.1    Roth, H.J.2    Thompson, M.3    Kantorow, M.4    Piatigorsky, J.5
  • 18
    • 0029893374 scopus 로고    scopus 로고
    • Developmental regulation of the chicken βB1-crystallin promoter in transgenic mice
    • Duncan, M. K., X. Li, H. Ogino, K. Yasuda, and J. Piatigorsky. 1996. Developmental regulation of the chicken βB1-crystallin promoter in transgenic mice. Mech. Dev. 57:79-89.
    • (1996) Mech. Dev. , vol.57 , pp. 79-89
    • Duncan, M.K.1    Li, X.2    Ogino, H.3    Yasuda, K.4    Piatigorsky, J.5
  • 19
    • 0028096639 scopus 로고
    • Two independent and interactive DNA-binding subdomains of the Pax-6 paired domain are regulated by alternative splicing
    • Epstein, J. A., T. Glaser, J. Cai, L. Jepeal, D. S. Walton, and R. L. Maas. 1994. Two independent and interactive DNA-binding subdomains of the Pax-6 paired domain are regulated by alternative splicing. Genes Dev. 8:2022-2034.
    • (1994) Genes Dev. , vol.8 , pp. 2022-2034
    • Epstein, J.A.1    Glaser, T.2    Cai, J.3    Jepeal, L.4    Walton, D.S.5    Maas, R.L.6
  • 20
    • 0029661444 scopus 로고    scopus 로고
    • Pax-6 and αB-crystallin/small heat shock protein gene regulation in the murine lens
    • Gopal-Srivastava, R., A. Cvekl, and J. Piatigorsky. 1996. Pax-6 and αB-crystallin/small heat shock protein gene regulation in the murine lens. J. Biol. Chem. 271:23029-23036.
    • (1996) J. Biol. Chem. , vol.271 , pp. 23029-23036
    • Gopal-Srivastava, R.1    Cvekl, A.2    Piatigorsky, J.3
  • 21
    • 0029002548 scopus 로고
    • The role of Pax-6 in eye and nasal development
    • Grindley, J. C., D. R. Davidson, and R. E. Hill. 1995. The role of Pax-6 in eye and nasal development. Development 121:1433-1442.
    • (1995) Development , vol.121 , pp. 1433-1442
    • Grindley, J.C.1    Davidson, D.R.2    Hill, R.E.3
  • 22
    • 0029781314 scopus 로고    scopus 로고
    • Spatial and temporal activity of the αB-crystallin/small heat shock protein gene promoter in transgenic mice
    • Haynes, J. I., M. K. Duncan, and J. Piatigorsky. 1996. Spatial and temporal activity of the αB-crystallin/small heat shock protein gene promoter in transgenic mice. Dev. Dyn. 207:75-88.
    • (1996) Dev. Dyn. , vol.207 , pp. 75-88
    • Haynes, J.I.1    Duncan, M.K.2    Piatigorsky, J.3
  • 23
    • 0021874994 scopus 로고
    • δ- And β-crystallin mRNA levels in the embryonic and posthatched chicken lens: Temporal and spatial changes during development
    • Hejtmancik, J. F., D. C. Beebe, H. Ostrer, and J. Piatigorsky. 1985. δ- and β-crystallin mRNA levels in the embryonic and posthatched chicken lens: temporal and spatial changes during development. Dev. Biol. 109:72-81.
    • (1985) Dev. Biol. , vol.109 , pp. 72-81
    • Hejtmancik, J.F.1    Beebe, D.C.2    Ostrer, H.3    Piatigorsky, J.4
  • 25
    • 0027026592 scopus 로고
    • Molecular genetics of the Pax gene family
    • Hill, R. E., and I. M. Hanson. 1992. Molecular genetics of the Pax gene family. Curr. Opin. Cell Biol. 4:967-972.
    • (1992) Curr. Opin. Cell Biol. , vol.4 , pp. 967-972
    • Hill, R.E.1    Hanson, I.M.2
  • 27
    • 0029837282 scopus 로고    scopus 로고
    • Cooperative interactions between paired domain and HD
    • Jun, S., and C. Desplan. 1996. Cooperative interactions between paired domain and HD. Development 122:2639-2650.
    • (1996) Development , vol.122 , pp. 2639-2650
    • Jun, S.1    Desplan, C.2
  • 28
    • 0024814234 scopus 로고
    • Bending of DNA by gene-J regulatory proteins: Construction and use of a DNA bending vector
    • Kim, J., C. Zwieb, C. Wu, and S. Adhya. 1989. Bending of DNA by gene-J regulatory proteins: construction and use of a DNA bending vector. Gene 85:15-23.
    • (1989) Gene , vol.85 , pp. 15-23
    • Kim, J.1    Zwieb, C.2    Wu, C.3    Adhya, S.4
  • 29
    • 0031033915 scopus 로고    scopus 로고
    • The Pax-6 homeobox gene is expressed throughout the corneal and conjunctival epithelia
    • Koroma, B. M., J.-M. Yang, and O. H. Sundin. 1997. The Pax-6 homeobox gene is expressed throughout the corneal and conjunctival epithelia. Invest. Ophthalmol. Visual Sci. 38:108-120.
    • (1997) Invest. Ophthalmol. Visual Sci. , vol.38 , pp. 108-120
    • Koroma, B.M.1    Yang, J.-M.2    Sundin, O.H.3
  • 31
    • 23444441161 scopus 로고
    • Pax-6 is first expressed in a region of ectoderm anterior to the early neural plate: Implications for stepwise determination of the lens
    • Li, H.-S., J.-M. Yang, R. D. Jacobson, D. Pasko, and O. Sundin. 1994. Pax-6 is first expressed in a region of ectoderm anterior to the early neural plate: implications for stepwise determination of the lens. Dev. Biol. 162:181-194.
    • (1994) Dev. Biol. , vol.162 , pp. 181-194
    • Li, H.-S.1    Yang, J.-M.2    Jacobson, R.D.3    Pasko, D.4    Sundin, O.5
  • 32
    • 0028895055 scopus 로고
    • Mouse Otx-2 functions in the formation and patterning of the rostral head
    • Matsuo, I., S. Kuratani, C. Kimura, N. Takeda, and S. Aizawa. 1995. Mouse Otx-2 functions in the formation and patterning of the rostral head. Genes Dev. 9:2646-2658.
    • (1995) Genes Dev. , vol.9 , pp. 2646-2658
    • Matsuo, I.1    Kuratani, S.2    Kimura, C.3    Takeda, N.4    Aizawa, S.5
  • 33
    • 0029886088 scopus 로고    scopus 로고
    • Lens-specific expression of a chicken βA3/A1-crystallin promoter fragment in transgenic mice
    • McDermott, J. B., A. Cvekl, and J. Piatigorsky. 1996. Lens-specific expression of a chicken βA3/A1-crystallin promoter fragment in transgenic mice. Biochem. Biophys. Res. Commun. 221:559-564.
    • (1996) Biochem. Biophys. Res. Commun. , vol.221 , pp. 559-564
    • McDermott, J.B.1    Cvekl, A.2    Piatigorsky, J.3
  • 34
    • 0029617682 scopus 로고
    • Six-3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development
    • Oliver, G., A. Mailhos, R. Wehr, N. G. Copeland, N. A. Jenkins, and P. Gruss. 1995. Six-3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. Development 121:4045-4055.
    • (1995) Development , vol.121 , pp. 4045-4055
    • Oliver, G.1    Mailhos, A.2    Wehr, R.3    Copeland, N.G.4    Jenkins, N.A.5    Gruss, P.6
  • 35
    • 0030460218 scopus 로고    scopus 로고
    • Ectopic lens induction in fish in response to the murine homeobox gene Six3
    • Oliver, G., F. Loosli, R. Koster, J. Wittbrodt, and P. Gruss. 1996. Ectopic lens induction in fish in response to the murine homeobox gene Six3. Mech. Dev. 60:233-239.
    • (1996) Mech. Dev. , vol.60 , pp. 233-239
    • Oliver, G.1    Loosli, F.2    Koster, R.3    Wittbrodt, J.4    Gruss, P.5
  • 36
    • 0019818161 scopus 로고
    • β-Crystallin mRNAs: Differential distribution in the developing chicken lens
    • Ostrer, H., D. C. Beebe, and J. Piatigorsky. 1981. β-Crystallin mRNAs: differential distribution in the developing chicken lens. Dev. Biol. 86:403-408.
    • (1981) Dev. Biol. , vol.86 , pp. 403-408
    • Ostrer, H.1    Beebe, D.C.2    Piatigorsky, J.3
  • 37
    • 0019786296 scopus 로고
    • Lens differentiation in vertebrates. A review of cellular and molecular features
    • Piatigorsky, J. 1981. Lens differentiation in vertebrates. A review of cellular and molecular features. Differentiation 19:134-53.
    • (1981) Differentiation , vol.19 , pp. 134-153
    • Piatigorsky, J.1
  • 38
    • 0010645914 scopus 로고    scopus 로고
    • Gene sharing in lens and cornea: Facts and implications
    • in press
    • Piatigorsky, J. Gene sharing in lens and cornea: facts and implications. Prog. Retin. Eye Res., in press.
    • Prog. Retin. Eye Res.
    • Piatigorsky, J.1
  • 39
    • 0027965633 scopus 로고
    • Homology of the eyeless gene of Drosophila to the small eye gene in mice and aniridia in humans
    • Quiring, R., U. Walldorf, U. Kloter, and W. Gehring. 1994. Homology of the eyeless gene of Drosophila to the small eye gene in mice and aniridia in humans. Science 265:785-789.
    • (1994) Science , vol.265 , pp. 785-789
    • Quiring, R.1    Walldorf, U.2    Kloter, U.3    Gehring, W.4
  • 40
    • 0029013329 scopus 로고
    • Pax-6 is essential for lens-specific expression of ζ-crystallin
    • Richardson, J., A. Cvekl, and G. Wistow. 1995. Pax-6 is essential for lens-specific expression of ζ-crystallin. Proc. Natl. Acad. Sci. USA 92:4676-4680.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 4676-4680
    • Richardson, J.1    Cvekl, A.2    Wistow, G.3
  • 41
    • 0029817433 scopus 로고    scopus 로고
    • Differential expression of αA -and αB-crystallin during murine ocular development
    • Robinson, M. L., and P. A. Overbeek. 1996. Differential expression of αA -and αB-crystallin during murine ocular development. Invest. Ophthalmol. Visual Sci. 37:2276-2284.
    • (1996) Invest. Ophthalmol. Visual Sci. , vol.37 , pp. 2276-2284
    • Robinson, M.L.1    Overbeek, P.A.2
  • 42
    • 0025969293 scopus 로고
    • Chicken βB1-crystallin gene expression: Presence of conserved functional polyomavirus enhancer-like and octamer binding-like promoter elements found in non-lens genes
    • Roth, H. J., G. C. Das, and J. Piatigorsky. 1991. Chicken βB1-crystallin gene expression: presence of conserved functional polyomavirus enhancer-like and octamer binding-like promoter elements found in non-lens genes. Mol. Cell. Biol. 11:1488-1499.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 1488-1499
    • Roth, H.J.1    Das, G.C.2    Piatigorsky, J.3
  • 43
    • 2642632405 scopus 로고
    • Quantitation of delta-crystallin messenger RNA during lens induction in chick embryos
    • Shinohara, T., and J. Piatigorsky. 1976. Quantitation of delta-crystallin messenger RNA during lens induction in chick embryos. Proc. Natl. Acad. Sci. USA 73:2808-2812.
    • (1976) Proc. Natl. Acad. Sci. USA , vol.73 , pp. 2808-2812
    • Shinohara, T.1    Piatigorsky, J.2
  • 44
    • 0027260743 scopus 로고
    • A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo
    • Simeone, A., D. Acampora, A. Mallamaci, A. Stornaiuolo, M. R. D'Apice, V. Nigro, and E. Boncinelli. 1993. A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo. EMBO J. 12:2735-2747.
    • (1993) EMBO J. , vol.12 , pp. 2735-2747
    • Simeone, A.1    Acampora, D.2    Mallamaci, A.3    Stornaiuolo, A.4    D'Apice, M.R.5    Nigro, V.6    Boncinelli, E.7
  • 45
    • 0028809870 scopus 로고
    • Loss of p53 function through PAX-mediated transcriptional repression
    • Stuart, E. T., R. Haffner, M. Oren, and P. Gruss. 1995. Loss of p53 function through PAX-mediated transcriptional repression. EMBO J. 14:5638-5645.
    • (1995) EMBO J. , vol.14 , pp. 5638-5645
    • Stuart, E.T.1    Haffner, R.2    Oren, M.3    Gruss, P.4
  • 46
    • 0028291690 scopus 로고
    • Convergent evolution of crystallin gene regulation in squid and chicken: The AP-1/ARE connection
    • Tomarev, S. I., M. K. Duncan, H. J. Roth, A. Cvekl, and J. Piatigorsky. 1994. Convergent evolution of crystallin gene regulation in squid and chicken: the AP-1/ARE connection. J. Mol. Evol. 39:134-143.
    • (1994) J. Mol. Evol. , vol.39 , pp. 134-143
    • Tomarev, S.I.1    Duncan, M.K.2    Roth, H.J.3    Cvekl, A.4    Piatigorsky, J.5
  • 48
    • 0023917935 scopus 로고
    • Lens crystallins: Evolution and expression of proteins for a highly specialized tissue
    • Wistow, G., and J. Piatigorsky. 1988. Lens crystallins: evolution and expression of proteins for a highly specialized tissue. Annu. Rev. Biochem. 57:479-504.
    • (1988) Annu. Rev. Biochem. , vol.57 , pp. 479-504
    • Wistow, G.1    Piatigorsky, J.2
  • 49
    • 0014276941 scopus 로고
    • Macromolecular events during differentiation of the chicken lens
    • Zwaan, J., and A. Ikeda. 1968. Macromolecular events during differentiation of the chicken lens. Exp. Eye Res. 7:301-311.
    • (1968) Exp. Eye Res. , vol.7 , pp. 301-311
    • Zwaan, J.1    Ikeda, A.2
  • 50
    • 0024670868 scopus 로고
    • DNA bending by negative regulatory proteins: Gal and Lac repressors
    • Zwieb, C., J. Kim, and S. Adhya. 1989. DNA bending by negative regulatory proteins: Gal and Lac repressors. Genes Dev. 3:606-611.
    • (1989) Genes Dev. , vol.3 , pp. 606-611
    • Zwieb, C.1    Kim, J.2    Adhya, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.