Role of ATP in fast excitatory synaptic potentials in locus coeruleus neurones of the rat

British Journal of Pharmacology

Volumn 122, Issue 3, 1997, Pages 423-430

  Nieber, Karen ^a   Poelchen, Wolfgang ^b   Illes, Peter ^b  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UNIVERSITY HOSPITAL LEIPZIG   (Germany)

Author keywords

ATP; Locus coeruleus; Noradrenaline

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CIBACRON BLUE F3GA; HEXAMETHONIUM; KYNURENIC ACID; NORADRENALIN; PICROTOXIN; PURINE P2 RECEPTOR; PYRIDOXAL 5 PHOSPHATE; STRYCHNINE; SURAMIN; TROPISETRON;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DENDRITE; DEPOLARIZATION; ELECTROSTIMULATION; HYPERPOLARIZATION; INHIBITORY POSTSYNAPTIC POTENTIAL; LOCUS CERULEUS; MALE; NERVE ENDING; NERVE FIBER; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; RAT; SYNAPTIC POTENTIAL;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ADENOSINE TRIPHOSPHATE; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; ELECTRIC STIMULATION; EXCITATORY AMINO ACID AGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; GABA ANTAGONISTS; KYNURENIC ACID; LOCUS COERULEUS; MALE; PICROTOXIN; PYRIDOXAL PHOSPHATE; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2; SURAMIN;

EID: 0030921149     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701386     Document Type: Article

References (47)

1. ABBRACCHIO, M.P. & BURNSTOCK, G. (1994). Purinoceptors: are there families of P2X and P2Y purinoceptors? Pharmacol. Ther., 64, 445-475.
2. ALLGAIER, C., WELLMANN, H., SCHOBERT, A., KURZ, G. & VON KÜGELGEN, I. (1995). Cultured chick sympathetic neurons: ATP-induced noradrenaline release and its blockade by nicotinic receptor antagonists. Naunyn-Schmiedeberg's Arch. Pharmacol., 252, 25-30.
3. BARNARD, E.A., BURNSTOCK, G. & WEBB, T.E. (1994). G protein-coupled receptors for ATP and other nucleotides; a new receptor family. Trends Pharmacol. Sci., 15, 67-70.
4. BEAN, B.P. (1992). Pharmacology and electrophysiology of ATP-activated ion channels. Trends Pharmacol. Sci., 13, 87-90.
5. BRAKE, A.J., WAGENBACH, M.J. & JULIUS, D. (1994). New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor. Nature, 371, 519-523.
6. BUELL, G., LEWIS, C., COLLO, G., NORTH, R.A. & SURPRENANT, A. (1996). An antagonist-insensitive P2X receptor expressed in epithelia and brain. EMBO J., 15, 55-62.
7. BÜLTMANN, R. & STARKE, K. (1994). P2-purinoceptor antagonists discriminate three contraction-mediating receptors for ATP in rat vas deferens. Naunyn-Schmiedeberg's Arch. Pharmacol., 349, 74-80.
8. BURNSTOCK, G. (1986). The changing face of autonomic neurotransmission. Acta Physiol. Scand., 126, 67-91.
9. CHERUBINI, E., NORTH, R.A. & WILLIAMS, J.T. (1988). Synaptic potentials in rat locus coeruleus neurones. J. Physiol., 496, 431-442.
10. 6 receptors and the distribution and properties of an extended family of ATP-gated ion channels. J. Neurosci., 16, 2495-2507.
11. EDWARDS, F.A., GIBB, A.J. & COLQUHOUN, D. (1992). ATP receptor-mediated synaptic currents in the central nervous system. Nature, 359, 144-147.
12. EGAN, T.M., HENDERSON, G., NORTH, R.A. & WILLIAMS, J.T. (1983). Noradrenaline-mediated synaptic inhibition in rat locus coeruleus neurones. J. Physiol., 345, 477-488.
13. EVANS, R.J., DERKACH, V. & SURPRENANT, A. (1992). ATP mediates fast synaptic transmission in mammalian neurons. Nature, 357, 503-505.
14. FINK, K. & GÖTHERT, M. (1990). Inhibition of N-methyl-D-aspartate-induced noradrenaline release by alcohols is related to their hydrophobicity. Eur. J. Pharmacol., 191, 225-229.
15. FREDHOLM, B.B., ABBRACCHIO, M.P., BURNSTOCK, G., DALY, J.W., HARDEN, T.K., JACOBSON, K.A., LEFF, P. & WILLIAMS, M. (1994). Nomenclature and classification of purinoceptors. Pharmacol. Rev., 46, 143-156.
16. FRÖHLICH, R., BOEHM, S. & ILLES, P. (1996). Pharmacological characterization of P2 purinoceptor types in rat locus coeruleus neurons. Eur. J. Pharmacol., 315, 255-261.
17. FURUKAWA, K., ISHIBASHI, H. & AKAIKE, N. (1994). ATP-induced inward current in neurons freshly dissociated from the tuberomamillary nucleus. J. Neurophysiol., 71, 868-873.
18. GALLIGAN, J.J. & BERTRAND, P.P. (1994). ATP mediates fast synaptic potentials in enteric neurons. J. Neurosci., 14, 7563-7571.
19. HARMS, L., FINTA, E.P., TSCHÖPL, M. & ILLES, P. (1992). Depolarization of rat locus coeruleus neurons by adenosine 5′-triphosphate. Neuroscience, 48, 941-952.
20. HIRUMA, H. & BOURQUE, C.W. (1995). P2 purinoceptor-mediated depolarization of rat supraoptic neurosecretory cells in vitro. J. Physiol., 489, 805-811.
21. HUMPHREY, P.P.A., BUELL, G., KENNEDY, I., KHAKH, B.S., MICHEL, A.D., SURPRENANT, A. & TREZISE, D.J. (1995). New insights on P2X purinoceptors. Naunyn-Schmiedeberg's Arch. Pharmacol., 352, 585-596.
22. ILLES, P. & NÖRENBERG, W. (1993). Neuronal ATP receptors and their mechanism of action. Trends Pharmacol. Sci., 14, 50-54.
23. ILES, P., NIEBER, K. & NORENBERG, W. (1995). Neuronal ATP receptors. In Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology, ed. Bellardinelli, L. & Pelleg, A. pp. 77-84. Norwell: Kluwer.
24. KENNEDY, C. (1990). P1- and P2-purinoceptor subtypes an update. Arch. Int. Pharmacodyn. Ther., 303, 30-50.
25. KENNEDY, C. & LEFF, P. (1995). How should P2X purinoceptors be classified pharmacologically? Trends Pharmacol. Sci., 16, 168-174.
26. KHAKH, B.S., HUMPHREY, P.P.A. & HENDERSON, G. (1997). ATP-gated cation channels (P2X purinoceptors) in neurones of the trigeminal mesencephalic nucleus (MNV). J. Physiol., 498, 709-715.
27. KIDD, E.J., GRAHAMES, C.B.A., SIMON, J., MICHEL, A.D., BARNARD, E.A. & HUMPHREY, P.P.A. (1995). Localization of P2X purinoceptor transcripts in the rat nervous system. Mol. Pharmacol., 48, 569-573.
28. KUPFERMANN, I. (1991). Functional studies of cotransmission. Physiol. Rev., 71, 683-732.
29. MOTIN, L. & BENNETT, M.R. (1995). Effect of P2-purinoceptor antagonists on glutamatergic transmission in the rat hippocampus. Br. J. Pharmacol., 115, 1276-1280.
30. NABEKURA, J., UENO, S., OGAWA, T. & AKAIKE, N. (1995). Colocalization of ATP and nicotinic ACh receptors in the identified vagal preganglionic neurone of rat. J. Physiol., 489, 519-527.
31. NAGY, J.I., BUSS, M. & DADDONA, P.E. (1986). On the innervation of trigeminal mesencephalic primary afferent neurons by adenosine deaminase-containing projections from the hypothalamus in the rat. Neuroscience, 17, 141-156.
32. NAKAZAWA, K., INOUE, K., ITO, K., KOIZUMI, S. & INOUE, K. (1995). Inhibition by suramin and reactive blue 2 of GABA and glutamate receptor channels in rat hippocampal neurons. Naunyn-Schmiedeberg's Arch. Pharmacol., 351, 202-208.
33. NIEBER, K., SEVCIK, J. & ILLES, P. (1995). Hypoxic changes in rat locus coeruleus neurons in vitro. J. Physiol., 486, 33-46.
34. OSMANOVIC, S.S. & SHEFNER, S.A. (1990). γ-Aminobutyric acid responses in rat locus coeruleus neurones in vitro: a current clamp and voltage-clamp study. J. Physiol., 421, 151-170.
35. REGENOLD, J.T., HAAS, H. & ILLES, P. (1988). Effects of purinoceptor agonists on electrophysiological properties of rat trigeminal mesencephalic neurones in vitro. Neurosci. Letts., 92, 347-350.
36. 1-receptors on rat locus coeruleus neurones. An intracellular electrophysiological study. Naunyn-Schmiedeberg's Arch. Pharmacol., 341, 225-231.
37. SHEN, K.-Z. & NORTH, R.A. (1993). Excitation of rat locus coeruleus neurons by adenosine 5′-triphosphate: ionic mechanism and receptor characterization. J. Neurosci., 13, 894-899.
38. SILINSKY, E.M. & GERZANICH, V. (1993). On the excitatory effects of ATP and its role as a neurotransmitter in coeliac neurons of the guinea-pig. J. Physiol., 464, 197-212.
39. STJÄRNE, L. (1989). Basic mechanisms and local modulation of nerve impulse-induced secretion of neurotransmitters from individual sympathetic nerve varicosities. Rev. Physiol. Biochem. Pharmacol., 112, 1-137.
40. SURPRENANT, A., BUELL, G. & NORTH, R.A. (1995). P2X receptors bring new structure to ligand-gated ion channels. Trends Neurosci., 18, 224-229.
41. VALERA, S., HUSSY, N., EVANS, R.J., ADAMI, N., NORTH, R.A., SURPRENANT, A. & BUELL, G. (1994). A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP. Nature 371, 516-519.
42. VON KÜGELGEN, I.V. & STARKE, K. (1991). Noradrenaline-ATP co-transmission in the sympathetic nervous system. Trends Pharmacol. Sci., 12, 319-324.
43. WEBB, T.E., SIMON, J., KRISHEK, B.J., BATESON, A.N., SMART, T.G., KING, B.K. BURNSTOCK, G. & BARNARD, E.A. (1993). Cloning and functional expression of a brain G-protein-coupled ATP receptor. FEBS Letts., 324, 219-225.
44. WILLIAMS, J.T., BOBKER, D.H. & HARRIS, G.C. (1991). Synaptic potentials in locus coeruleus neurons in brain slices. Prog. Brain Res., 88, 167-172.
45. ZHOU, X. & GALLIGAN, J.J. (1996). P2X purinoceptors in cultured myenteric neurons of guinea-pig small intestine J. Physiol., 496, 719-729.
46. ZIGANSHIN, A.U., HOYLE, C.H.V., LAMBRECHT, G., MUTSCHLER, E., BÄUMERT, H.G. & BURNSTOCK, G. (1994). Selective antagonism by PPADS at P2X-purinoceptors in rabbit isolated blood vessels. Br. J. Pharmacol., 111, 923-929.
47. ZIMMERMANN, H. (1994). Signalling via ATP in the nervous system. Trends Neurosci., 17, 420-426.