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Volumn 2, Issue 4, 1999, Pages 410-414

Recent developments in the biology of respiratory syncytial virus: Are vaccines and new treatments just round the corner?

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA VACCINE;

EID: 0033178776     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5274(99)80072-1     Document Type: Review
Times cited : (14)

References (46)
  • 1
    • 0030793204 scopus 로고    scopus 로고
    • Safety and immunogenicity of a respiratory syncytial virus subunit vaccine (PFP-2) in the institutionalized elderly
    • Falsey AR, Walsh EE: Safety and immunogenicity of a respiratory syncytial virus subunit vaccine (PFP-2) in the institutionalized elderly. Vaccine 1997, 15:1130-1132.
    • (1997) Vaccine , vol.15 , pp. 1130-1132
    • Falsey, A.R.1    Walsh, E.E.2
  • 2
    • 0029986076 scopus 로고    scopus 로고
    • Impact of influenza and respiratory syncytial virus on mortality in England and Wales from January 1975 to December 1990
    • Nicholson KG: Impact of influenza and respiratory syncytial virus on mortality in England and Wales from January 1975 to December 1990. Epidemiol Infect 1996, 116:51-63.
    • (1996) Epidemiol Infect , vol.116 , pp. 51-63
    • Nicholson, K.G.1
  • 4
    • 0032147035 scopus 로고    scopus 로고
    • Immune responses of infants to infection with respiratory viruses and live attenuated respiratory virus candidate vaccines
    • Crowe JEJ: Immune responses of infants to infection with respiratory viruses and live attenuated respiratory virus candidate vaccines. Vaccine 1998, 16:1423-1432.
    • (1998) Vaccine , vol.16 , pp. 1423-1432
    • Crowe, J.E.J.1
  • 5
    • 0032167369 scopus 로고    scopus 로고
    • Subcellular site of expression and route of vaccination influence pulmonary eosinophilia following respiratory syncytial virus challenge in BALB/c mice sensitized to the attachment G protein
    • Bembridge GP, Garcia BR, Lopez JA, Melero JA, Taylor G: Subcellular site of expression and route of vaccination influence pulmonary eosinophilia following respiratory syncytial virus challenge in BALB/c mice sensitized to the attachment G protein. J Immunol 1998, 161:2473-2480. Mice immunised with recombinant vaccinia encoding membrane-bound or secreted forms of protein G were challenged with respiratory syncytial virus (RSV). The secreted form of protein G induced more marked lung eosinophilia, but eosinophilia was not seen in mice vaccinated intraperitoneally.
    • (1998) J Immunol , vol.161 , pp. 2473-2480
    • Bembridge, G.P.1    Garcia, B.R.2    Lopez, J.A.3    Melero, J.A.4    Taylor, G.5
  • 6
    • 0031925039 scopus 로고    scopus 로고
    • Priming with secreted glycoprotein G of respiratory syncytial virus (RSV) augments interleukin-5 production and tissue eosinophilia after RSV challenge
    • Johnson TR, Johnson JE, Roberts SR, Wertz GW, Parker RA, Graham BS: Priming with secreted glycoprotein G of respiratory syncytial virus (RSV) augments interleukin-5 production and tissue eosinophilia after RSV challenge. J Virol 1998, 72:2871-2880. Secreted protein G made by recombinant vaccinia primes for more severe illness during respiratory syncytial virus (RSV) challenge, with greater lung eosinophilia and interleukin-5 production.
    • (1998) J Virol , vol.72 , pp. 2871-2880
    • Johnson, T.R.1    Johnson, J.E.2    Roberts, S.R.3    Wertz, G.W.4    Parker, R.A.5    Graham, B.S.6
  • 7
    • 0030795092 scopus 로고    scopus 로고
    • + T lymphocytes downregulate T helper cell type 2 cytokine secretion and pulmonary eosinophilia during experimental murine respiratory syncytial virus infection
    • + T lymphocytes downregulate T helper cell type 2 cytokine secretion and pulmonary eosinophilia during experimental murine respiratory syncytial virus infection. J Exp Med 1997, 186:421-432.
    • (1997) J Exp Med , vol.186 , pp. 421-432
    • Srikiatkhachorn, A.1    Braciale, T.J.2
  • 8
    • 0031441754 scopus 로고    scopus 로고
    • + T-cells control Th2-driven pathology during pulmonary respiratory syncytial virus infection
    • + T-cells control Th2-driven pathology during pulmonary respiratory syncytial virus infection. Eur J Immunol 1997, 27:3341-3349.
    • (1997) Eur J Immunol , vol.27 , pp. 3341-3349
    • Hussell, T.1    Baldwin, C.J.2    O'Garra, A.3    Openshaw, P.J.M.4
  • 9
    • 0028902237 scopus 로고
    • Evolution of subgroup A respiratory syncytial virus: Evidence for progressive accumulation of amino acid changes in the attachment protein
    • Cane PA, Pringle CR: Evolution of subgroup A respiratory syncytial virus: Evidence for progressive accumulation of amino acid changes in the attachment protein. J Virol 1995, 69:2918-2925.
    • (1995) J Virol , vol.69 , pp. 2918-2925
    • Cane, P.A.1    Pringle, C.R.2
  • 10
    • 0031670085 scopus 로고    scopus 로고
    • Circulation patterns of genetically distinct group A and B strains of human respiratory syncytial virus in a community
    • Peret TC, Hall CB, Schnabel KC, Golub JA, Anderson LJ: Circulation patterns of genetically distinct group A and B strains of human respiratory syncytial virus in a community. J Gen Virol 1998, 79:2221-2229.
    • (1998) J Gen Virol , vol.79 , pp. 2221-2229
    • Peret, T.C.1    Hall, C.B.2    Schnabel, K.C.3    Golub, J.A.4    Anderson, L.J.5
  • 11
    • 0031687449 scopus 로고    scopus 로고
    • Antigenic and genetic diversity among the attachment proteins of group A respiratory syncytial viruses that have caused repeat infections in children
    • Sullender WM, Mufson MA, Prince GA, Anderson LJ, Wertz GW: Antigenic and genetic diversity among the attachment proteins of group A respiratory syncytial viruses that have caused repeat infections in children. J Infect Dis 1998, 178:925-932.
    • (1998) J Infect Dis , vol.178 , pp. 925-932
    • Sullender, W.M.1    Mufson, M.A.2    Prince, G.A.3    Anderson, L.J.4    Wertz, G.W.5
  • 12
    • 0031869506 scopus 로고    scopus 로고
    • Unusual antigenic and genetic characteristics of human respiratory syncytial viruses isolated in Cuba
    • Valdes O, Martinez I, Valdivia A, Cancio R, Savon C, Goyenechea A, Melero JA: Unusual antigenic and genetic characteristics of human respiratory syncytial viruses isolated in Cuba. J Virol 1998, 72:7589-7592.
    • (1998) J Virol , vol.72 , pp. 7589-7592
    • Valdes, O.1    Martinez, I.2    Valdivia, A.3    Cancio, R.4    Savon, C.5    Goyenechea, A.6    Melero, J.A.7
  • 13
    • 0029584042 scopus 로고
    • Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5′ proximal open reading frame of the M2 mRNA in gene expression and provides a capability for vaccine development
    • Collins PL, Hill MG, Camargo E, Grosfeld H, Chanock RM, Murphy BR: Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5′ proximal open reading frame of the M2 mRNA in gene expression and provides a capability for vaccine development. Proc Natl Acad Sci USA 1995, 92:11563-11567.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11563-11567
    • Collins, P.L.1    Hill, M.G.2    Camargo, E.3    Grosfeld, H.4    Chanock, R.M.5    Murphy, B.R.6
  • 14
    • 0032506277 scopus 로고    scopus 로고
    • Recombinant human respiratory syncytial virus (RSV) from cDNA and construction of subgroup A and B chimeric RSV
    • Jin H, Clarke D, Zhou HZ, Cheng X, Coelingh K, Bryant M, Li S: Recombinant human respiratory syncytial virus (RSV) from cDNA and construction of subgroup A and B chimeric RSV. Virology 1998, 251:206-214. Infectious human RSV was produced from a cDNA clone that contains 15,222 nucleotides of RSV genome derived from the A2 strain of subgroup A. Heterotypic virus with surface protein G expression from bovine RSV was also produced.
    • (1998) Virology , vol.251 , pp. 206-214
    • Jin, H.1    Clarke, D.2    Zhou, H.Z.3    Cheng, X.4    Coelingh, K.5    Bryant, M.6    Li, S.7
  • 15
    • 0033079672 scopus 로고    scopus 로고
    • Recombinant vesicular stomatitis virus expressing respiratory syncytial virus (RSV) glycoproteins: RSV fusion protein can mediate infection and cell fusion
    • Kahn JS, Schnell MJ, Buonocore L, Rose JK: Recombinant vesicular stomatitis virus expressing respiratory syncytial virus (RSV) glycoproteins: RSV fusion protein can mediate infection and cell fusion. Virology 1999, 254:81-91. This genetically modified vector vesicular stomatitis virus (VSV) vector can package RSV surface proteins. This recombinant virus could not have arisen in nature. The potential for producing candidate vaccines is exciting, but needs to be carefully balanced against the potential risks of producing novel viruses.
    • (1999) Virology , vol.254 , pp. 81-91
    • Kahn, J.S.1    Schnell, M.J.2    Buonocore, L.3    Rose, J.K.4
  • 16
    • 0032145583 scopus 로고    scopus 로고
    • A single nucleotide substitution in the transcription start signal of the M2 gene of respiratory syncytial virus vaccine candidate cpts248/404 is the major determinant of the temperature-sensitive and attenuation phenotypes
    • Whitehead SS, Firestone CY, Collins PL, Murphy BR: A single nucleotide substitution in the transcription start signal of the M2 gene of respiratory syncytial virus vaccine candidate cpts248/404 is the major determinant of the temperature-sensitive and attenuation phenotypes. Virology 1998, 247:232-239.
    • (1998) Virology , vol.247 , pp. 232-239
    • Whitehead, S.S.1    Firestone, C.Y.2    Collins, P.L.3    Murphy, B.R.4
  • 17
    • 0033514943 scopus 로고    scopus 로고
    • Interferon gamma expressed by a recombinant respiratory syncytial virus attenuates virus replication in mice without compromising immunogenicity
    • Bukreyev A, Whitehead SS, Bukreyeva N, Murphy B, Collins PL: Interferon gamma expressed by a recombinant respiratory syncytial virus attenuates virus replication in mice without compromising immunogenicity. Proc Natl Acad Sci USA 1999, 96:2367-2372. A genetically engineered novel recombinant respiratory syncytial virus (RSV) encoding murine interferon-gamma limits its own replication in the respiratory tract, but still induces an excellent protective immune response.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2367-2372
    • Bukreyev, A.1    Whitehead, S.S.2    Bukreyeva, N.3    Murphy, B.4    Collins, P.L.5
  • 18
    • 0031777341 scopus 로고    scopus 로고
    • Identification of the respiratory syncytial virus proteins required for formation and passage of helper-dependent infectious particles
    • Teng MN, Collins PL: Identification of the respiratory syncytial virus proteins required for formation and passage of helper-dependent infectious particles. J Virol 1998, 72:5707-5716.
    • (1998) J Virol , vol.72 , pp. 5707-5716
    • Teng, M.N.1    Collins, P.L.2
  • 19
    • 0032101551 scopus 로고    scopus 로고
    • Eliminating a region of respiratory syncytial virus attachment protein allows induction of protective immunity without vaccine-enhanced lung eosinophilia
    • Sparer TE, Matthews S, Hussell T, Rae AJ, Garcia-Barreno B, Melero JA, Openshaw PJM: Eliminating a region of respiratory syncytial virus attachment protein allows induction of protective immunity without vaccine-enhanced lung eosinophilia. J Exp Med 1998, 187:1921-1926. These studies used viruses containing frameshifts that altered the carboxyterminus of the G protein, and identified residues 193-205 to be responsible for G protein induced weight loss and lung eosinophilia. This region, however, was not necessary for induction of protective immunity.
    • (1998) J Exp Med , vol.187 , pp. 1921-1926
    • Sparer, T.E.1    Matthews, S.2    Hussell, T.3    Rae, A.J.4    Garcia-Barreno, B.5    Melero, J.A.6    Openshaw, P.J.M.7
  • 20
    • 0032538913 scopus 로고    scopus 로고
    • Atypical pulmonary eosinophilia is mediated by a specific amino acid sequence of the attachment (G) protein of respiratory syncytial virus
    • Tebbey PW, Hagen M, Hancock GE: Atypical pulmonary eosinophilia is mediated by a specific amino acid sequence of the attachment (G) protein of respiratory syncytial virus. J Exp Med 1998, 188:1967-1972.
    • (1998) J Exp Med , vol.188 , pp. 1967-1972
    • Tebbey, P.W.1    Hagen, M.2    Hancock, G.E.3
  • 23
    • 0031949557 scopus 로고    scopus 로고
    • Cell specific expression of RANTES, MCP-1, and MIP-1α by lower airway epithelial cells and eosinophils infected with respiratory syncytial virus
    • Olszewska PB, Casola A, Saito T, Alam R, Crowe SE, Mei F, Ogra PL, Garofalo RP: Cell specific expression of RANTES, MCP-1, and MIP-1α by lower airway epithelial cells and eosinophils infected with respiratory syncytial virus. J Virol 1998, 72:4756-4764.
    • (1998) J Virol , vol.72 , pp. 4756-4764
    • Olszewska, P.B.1    Casola, A.2    Saito, T.3    Alam, R.4    Crowe, S.E.5    Mei, F.6    Ogra, P.L.7    Garofalo, R.P.8
  • 24
    • 0031949557 scopus 로고    scopus 로고
    • Cell-specific expression of RANTES, MCP-1, and MIP-1alpha by lower airway epithelial cells and eosinophils infected with respiratory syncytial virus
    • Olszewska PB, Casola A, Saito T, Alam R, Crowe SE, Mei F, Ogra PL, Garofalo RP: Cell-specific expression of RANTES, MCP-1, and MIP-1alpha by lower airway epithelial cells and eosinophils infected with respiratory syncytial virus. J Virol 1998, 72:4756-4764.
    • (1998) J Virol , vol.72 , pp. 4756-4764
    • Olszewska, P.B.1    Casola, A.2    Saito, T.3    Alam, R.4    Crowe, S.E.5    Mei, F.6    Ogra, P.L.7    Garofalo, R.P.8
  • 25
    • 0033065482 scopus 로고    scopus 로고
    • Elevated cytokine concentrations in the nasopharyngeal and tracheal secretions of children with respiratory syncytial virus disease
    • Sheeran P, Jafri H, Carubelli C, Saavedra J, Johnson C, Krisher K, Sanchez PJ, Ramilo O: Elevated cytokine concentrations in the nasopharyngeal and tracheal secretions of children with respiratory syncytial virus disease. Pediatr Infect Dis J 1999, 18:115-122.
    • (1999) Pediatr Infect Dis J , vol.18 , pp. 115-122
    • Sheeran, P.1    Jafri, H.2    Carubelli, C.3    Saavedra, J.4    Johnson, C.5    Krisher, K.6    Sanchez, P.J.7    Ramilo, O.8
  • 26
    • 0031808672 scopus 로고    scopus 로고
    • T cell subset analysis in peripheral blood of children with RSV bronchiolitis
    • De WW, Twilhaar WN, Kimpen JL: T cell subset analysis in peripheral blood of children with RSV bronchiolitis. Scand J Infect Dis 1998, 30:77-80.
    • (1998) Scand J Infect Dis , vol.30 , pp. 77-80
    • De, W.W.1    Twilhaar, W.N.2    Kimpen, J.L.3
  • 27
    • 0032502692 scopus 로고    scopus 로고
    • Structural homology of the central conserved region of the attachment protein G of respiratory syncytial virus with the fourth subdomain of 55 kDa tumor necrosis factor receptor
    • Langedijk JP, de Groot BL, Berendsen HJ, van Oirschot JT: Structural homology of the central conserved region of the attachment protein G of respiratory syncytial virus with the fourth subdomain of 55 kDa tumor necrosis factor receptor. Virology 1998, 243:293-302. The highly conserved cystine-rich ectodomain of the respiratory syncytial virus (RSV) G protein is flanked by two mucin-like regions. This paper describes a structural homology between this conserved domain and the fourth subdomain of the 55 kDa tumour necrosis factor receptor.
    • (1998) Virology , vol.243 , pp. 293-302
    • Langedijk, J.P.1    De Groot, B.L.2    Berendsen, H.J.3    Van Oirschot, J.T.4
  • 28
    • 0031848862 scopus 로고    scopus 로고
    • Respiratory syncytial virus vaccines
    • Dudas RA, Karron RA: Respiratory syncytial virus vaccines. Clin Microbiol Rev 1998, 11:430-439.
    • (1998) Clin Microbiol Rev , vol.11 , pp. 430-439
    • Dudas, R.A.1    Karron, R.A.2
  • 29
    • 0031906484 scopus 로고    scopus 로고
    • Safety and immunogenicity of a purified F protein respiratory syncytial virus (PFP-2) vaccine in seropositive children with bronchopulmonary dysplasia
    • Groothuis JR, King SJ, Hogerman DA, Paradiso PR, Simoes EA: Safety and immunogenicity of a purified F protein respiratory syncytial virus (PFP-2) vaccine in seropositive children with bronchopulmonary dysplasia. J Infect Dis 1998, 177:467-469.
    • (1998) J Infect Dis , vol.177 , pp. 467-469
    • Groothuis, J.R.1    King, S.J.2    Hogerman, D.A.3    Paradiso, P.R.4    Simoes, E.A.5
  • 30
    • 0031894642 scopus 로고    scopus 로고
    • Sequential annual administration of purified fusion protein vaccine against respiratory syncytial virus in children with cystic fibrosis
    • Piedra PA, Grace S, Jewell A, Spinelli S, Hogerman DA, Malinoski F, Hiatt PW: Sequential annual administration of purified fusion protein vaccine against respiratory syncytial virus in children with cystic fibrosis. Pediatr Infect Dis J 1998, 17:217-224.
    • (1998) Pediatr Infect Dis J , vol.17 , pp. 217-224
    • Piedra, P.A.1    Grace, S.2    Jewell, A.3    Spinelli, S.4    Hogerman, D.A.5    Malinoski, F.6    Hiatt, P.W.7
  • 31
    • 0032147233 scopus 로고    scopus 로고
    • Maternal immunization against viral disease
    • Englund J, Glezen WP, Piedra PA: Maternal immunization against viral disease. Vaccine 1998, 16:1456-1463.
    • (1998) Vaccine , vol.16 , pp. 1456-1463
    • Englund, J.1    Glezen, W.P.2    Piedra, P.A.3
  • 32
    • 0031977449 scopus 로고    scopus 로고
    • Recombinant respiratory syncytial virus (RSV) bearing a set of mutations from cold-passaged RSV is attenuated in chimpanzees
    • Whitehead SS, Juhasz K, Firestone CY, Collins PL, Murphy BR: Recombinant respiratory syncytial virus (RSV) bearing a set of mutations from cold-passaged RSV is attenuated in chimpanzees. J Virol 1998, 72:4467-4471.
    • (1998) J Virol , vol.72 , pp. 4467-4471
    • Whitehead, S.S.1    Juhasz, K.2    Firestone, C.Y.3    Collins, P.L.4    Murphy, B.R.5
  • 33
    • 18344410538 scopus 로고    scopus 로고
    • Protection against respiratory syncytial virus infection by DNA immunization
    • Li X, Sambhara S, Li CX, Ewasyshyn M, Parrington M, Caterini J, James O, Cates G, Du RP, Klein M: Protection against respiratory syncytial virus infection by DNA immunization. J Exp Med 1998, 188:681-688. Plasmid DNA expressing fusion protein (F) induces neutralising antibody and cytotoxic T lymphocytes (CTL) in mice, protects against re-infection and could switch an established Th2 response to Th1.
    • (1998) J Exp Med , vol.188 , pp. 681-688
    • Li, X.1    Sambhara, S.2    Li, C.X.3    Ewasyshyn, M.4    Parrington, M.5    Caterini, J.6    James, O.7    Cates, G.8    Du, R.P.9    Klein, M.10
  • 34
    • 17944391919 scopus 로고    scopus 로고
    • Respiratory syncytial virus immune globulin for prophylaxis against respiratory syncytial virus disease in infants and children with congenital heart disease
    • Simoes EA, Sondheimer HM, Top-FH J, Meissner HC, Welliver RC, Kramer AA, Groothuis JR: Respiratory syncytial virus immune globulin for prophylaxis against respiratory syncytial virus disease in infants and children with congenital heart disease. J Pediatr 1998, 133:492-499.
    • (1998) J Pediatr , vol.133 , pp. 492-499
    • Simoes, E.A.1    Sondheimer, H.M.2    Top-FH, J.3    Meissner, H.C.4    Welliver, R.C.5    Kramer, A.A.6    Groothuis, J.R.7
  • 35
    • 0031683919 scopus 로고    scopus 로고
    • Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants
    • The IMpact-RSV Study Group: Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants. Pediatrics 1998, 102:531-537.
    • (1998) Pediatrics , vol.102 , pp. 531-537
  • 36
    • 0031958658 scopus 로고    scopus 로고
    • Isolation of a second recombinant human respiratory syncytial virus monoclonal antibody fragment (Fab RSVF2-5) that exhibits therapeutic efficacy in vivo
    • Crowe-JE J, Gilmour PS, Murphy BR, Chanock RM, Duan L, Pomerantz RJ, Pilkington GR: Isolation of a second recombinant human respiratory syncytial virus monoclonal antibody fragment (Fab RSVF2-5) that exhibits therapeutic efficacy in vivo. J Infect Dis 1998, 177:1073-1076.
    • (1998) J Infect Dis , vol.177 , pp. 1073-1076
    • Crowe, J.E.J.1    Gilmour, P.S.2    Murphy, B.R.3    Chanock, R.M.4    Duan, L.5    Pomerantz, R.J.6    Pilkington, G.R.7
  • 37
    • 0031978929 scopus 로고    scopus 로고
    • Passive protection of gnotobiotic calves using monoclonal antibodies directed at different epitopes on the fusion protein of bovine respiratory syncytial virus
    • Thomas LH, Cook RS, Wyld SG, Furze JM, Taylor G: Passive protection of gnotobiotic calves using monoclonal antibodies directed at different epitopes on the fusion protein of bovine respiratory syncytial virus. J Infect Dis 1998, 177:874-880.
    • (1998) J Infect Dis , vol.177 , pp. 874-880
    • Thomas, L.H.1    Cook, R.S.2    Wyld, S.G.3    Furze, J.M.4    Taylor, G.5
  • 38
    • 0031850264 scopus 로고    scopus 로고
    • Costs and benefits of respiratory syncytial virus immunoglobulin to prevent hospitalization for lower respiratory tract illness in very low birth weight infants
    • O'Shea TM, Sevick MA, Givner LB: Costs and benefits of respiratory syncytial virus immunoglobulin to prevent hospitalization for lower respiratory tract illness in very low birth weight infants. Pediatr Infect Dis J 1998, 17:587-593.
    • (1998) Pediatr Infect Dis J , vol.17 , pp. 587-593
    • O'Shea, T.M.1    Sevick, M.A.2    Givner, L.B.3
  • 39
    • 0031819352 scopus 로고    scopus 로고
    • RD6-2198, a novel betain-type fluoroalkylated oligomer, inhibits the replications of human immunodeficiency virus type 1 and other enveloped viruses
    • Fujiwara M, Ashida N, Okamoto M, Mizuta T, Ide T, Hanasaki Y, Katsuura K, Sawada H, Shigeta S, Konno K et al.: RD6-2198, a novel betain-type fluoroalkylated oligomer, inhibits the replications of human immunodeficiency virus type 1 and other enveloped viruses. Antiviral Res 1998, 38:141-149.
    • (1998) Antiviral Res , vol.38 , pp. 141-149
    • Fujiwara, M.1    Ashida, N.2    Okamoto, M.3    Mizuta, T.4    Ide, T.5    Hanasaki, Y.6    Katsuura, K.7    Sawada, H.8    Shigeta, S.9    Konno, K.10
  • 40
    • 0032555288 scopus 로고    scopus 로고
    • Potent inhibition of respiratory syncytial virus replication using a 2-5A-antisense chimera targeted to signals within the virus genomic RNA
    • Player MR, Barnard DL, Torrence PF: Potent inhibition of respiratory syncytial virus replication using a 2-5A-antisense chimera targeted to signals within the virus genomic RNA. Proc Natl Acad Sci USA 1998, 95:8874-8879. Interferon induces 2-5A, which activates RNAase L that degrades viral RNA. Chemical conjugation of 2-5A to an antisense oligonucleotide was used to target RNAase L to the respiratory syncytial virus (RSV) RNA and cause its selective destruction. An antisense chimera (NIH351) was much more potent than ribavirin against RSV.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8874-8879
    • Player, M.R.1    Barnard, D.L.2    Torrence, P.F.3
  • 41
    • 0032428340 scopus 로고    scopus 로고
    • Anaphylactic sensitisation to aeroantigen during respiratory virus infection
    • O'Donnell DR, Openshaw PJM: Anaphylactic sensitisation to aeroantigen during respiratory virus infection. Clin Exp Allergy 1998, 28:1501-1508.
    • (1998) Clin Exp Allergy , vol.28 , pp. 1501-1508
    • O'Donnell, D.R.1    Openshaw, P.J.M.2
  • 42
    • 0030882725 scopus 로고    scopus 로고
    • Allergic sensitization increases airway reactivity in guinea pigs with respiratory syncytial virus bronchiolitis
    • Robinson PJ, Hegele RG, Schellenberg RR: Allergic sensitization increases airway reactivity in guinea pigs with respiratory syncytial virus bronchiolitis. J Allergy Clin Immunol 1997, 100:492-498.
    • (1997) J Allergy Clin Immunol , vol.100 , pp. 492-498
    • Robinson, P.J.1    Hegele, R.G.2    Schellenberg, R.R.3
  • 44
    • 0031969704 scopus 로고    scopus 로고
    • Family size, childhood infections and atopic diseases. The Aberdeen WHEASE Group
    • Bodner C, Godden D, Seaton A: Family size, childhood infections and atopic diseases. The Aberdeen WHEASE Group. Thorax 1998, 53:28-32.
    • (1998) Thorax , vol.53 , pp. 28-32
    • Bodner, C.1    Godden, D.2    Seaton, A.3
  • 45
    • 0032528433 scopus 로고    scopus 로고
    • Respiratory syncytial virus-induced RANTES production from human bronchial epithelial cells is dependent on nuclear factor-kappa B nuclear binding and is inhibited by adenovirus-mediated expression of inhibitor of kappa B alpha
    • Thomas LH, Friedland JS, Sharland M, Becker S: Respiratory syncytial virus-induced RANTES production from human bronchial epithelial cells is dependent on nuclear factor-kappa B nuclear binding and is inhibited by adenovirus-mediated expression of inhibitor of kappa B alpha. J Immunol 1998, 161:1007-1016.
    • (1998) J Immunol , vol.161 , pp. 1007-1016
    • Thomas, L.H.1    Friedland, J.S.2    Sharland, M.3    Becker, S.4
  • 46
    • 0031596773 scopus 로고    scopus 로고
    • The major component of I kappa B alpha proteolysis occurs independently of the proteasome pathway in respiratory syncytial virus-infected pulmonary epithelial cells
    • Jamaluddin M, Casola A, Garofalo RP, Han Y, Elliott T, Ogra PL, Brasier AR: The major component of I kappa B alpha proteolysis occurs independently of the proteasome pathway in respiratory syncytial virus-infected pulmonary epithelial cells. J Virol 1998, 72:4849-4857.
    • (1998) J Virol , vol.72 , pp. 4849-4857
    • Jamaluddin, M.1    Casola, A.2    Garofalo, R.P.3    Han, Y.4    Elliott, T.5    Ogra, P.L.6    Brasier, A.R.7


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