Elevated cytokine concentrations in the nasopharyngeal and tracheal secretions of children with respiratory syncytial virus disease

Pediatric Infectious Disease Journal

Volumn 18, Issue 2, 1999, Pages 115-122

  Sheeran, Paul ^a   Jafri, Hasan ^a   Carubelli, Cecilia ^a   Saavedra, Jesus ^a   Johnson, Chris ^a   Krisher, Karen ^a   Sánchez, Pablo J ^a   Ramilo, Octavio ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Bronchiolitis; Chemokines; Cytokines; Pneumonia; Respiratory syncytial virus

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1; RANTES;

ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOMODULATION; IMMUNOPATHOLOGY; INFANT; LEUKOCYTE COUNT; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; THROAT CULTURE; TRACHEOBRONCHIAL TOILET;

EID: 0033065482     PISSN: 08913668     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006454-199902000-00007     Document Type: Article

References (37)

1. Wells T, Peitsch M. The chemokine information source: identification and characterization of novel chemokines using the WorldWideWeb and expressed sequence tag databases. J Leukoc Biol 1997;61:545-50.
2. Saito T, Deskin R, Casola A, et al. Respiratory syncytial virus induces selective production of the chemokine RANTES by upper airway epithelial cells. J Infect Dis 1997;175:497-504.
3. Luster A. Chemokines: chemotactic cytokines that mediate inflammation. N Engl J Med 1997;338:436-45.
4. Zhang L, Redington A, Holgate S. RANTES: a novel mediator of allergic inflammation? Clin Exp Allergy 1994;24:899-904.
5. Kunkel S, Standiford T, Kasahara K, Strieter R. Interleukin-8 (IL-8): the major neutrophil chemotactic factor in the lung. Exp Lung Res 1991;17:17-23.
6. Chollet-Martin S, Montravers P, Gibert C, et al. High level of interleukin-8 in the blood and alveolar spaces of patients with pneumonia and adult respiratory distress syndrome. Infection and Immunity 1993;61:4553-9.
7. Meduri G, Kohler G, Headley S, Tolley E, Stentz F, Postlethwaite A. Inflammatory cytokines in the BAL of patients with ARDS. Chest 1995;108:1303-14.
8. Schutte H, Lohmeyer J, Rosseau S, et al. Bronchoalveolar and systemic cytokine profiles in patients with ARDS, severe pneumonia and cardiogenic pulmonary edema. Eur Respir J 1996;9:1858-67.
9. Miller E, Cohen A, Matthay M. Increased interleukin-8 concentrations in the pulmonary edema fluid of patients with acute respiratory distress syndrome from sepsis. Crit Care Med 1996;24:1448-54.
10. Donnelly S, Strieter R, Kunkel S, et al. Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups. Lancet 1993;341:643-7.
11. Becker S, Koren H, Henke D. Interleukin-8 expression in normal nasal epithelium and its modulation by infection with respiratory syncytial virus and cytokines tumor necrosis factor, interleukin-1, and interleukin-6. Am J Respir Cell Mol Biol 1993;8:20-7.
12. Olszewska-Pazdrak B, Casola A, Saito T, et al. Cell-specific expression of RANTES, MCP-1, and MIP-1 alpha by lower airway epithelial cells and eosinophils infected with respiratory syncytial virus. J Virol 1998;72:4756-64.
13. Becker S, Reed W, Henderson F, Noah T. RSV infection of human airway epithelial cells causes production of the beta-chemokine RANTES. Am J Physiol 1997;272:L512-20.
14. Jiang Z, Kunimoto M, Patel JA. Autocrine regulation and experimental modulation of interluekin-6 expression by human pulmonary epithelial cells infected with respiratory syncytial virus. J Virol 1998;72:2496-9.
15. Panuska J, Merolla R, Rebert N, et al. Respiratory syncytial virus induces interleukin-10 by human alveolar macrophages. J Clin Invest 1995;96:2445-53.
16. Chollet-Martin S, Jourdain B, Gibert C, Elbim C, Chastre J, Gougerot-Pocidalo M. Interactions between neutrophils and cytokines in blood and alveolar spaces during ARDS. Am J Respir Crit Care Med 1996;153:594-601.
17. Meduri G, Headley S, Kohler G, et al. Persistent elevation of inflammatory cytokines predicts a poor outcome in ARDS. Chest 1995;107:1062-73.
18. Arnold R, Konig B, Galatti H, Werchau H, Konig W. Cytokine (IL-8, IL-6, TNF-alpha) and soluble TNF receptor-I release from human peripheral blood mononuclear cells after respiratory syncytial virus infection. Immunology 1995;85:364-72.
19. Goldman M, Marchant A, Schandene L. Endogenous interleukin-10 in inflammatory disorders: regulatory roles and pharmacological modulation. Ann NY Acad Sci 1996;796: 282-93.
20. Murray J, Matthay M, Luce J, Flick M. An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis 1988;138:720-3.
21. Kisch A, Johnson K. A plaque assay for respiratory syncytial virus. Proc Soc Exp Biol Med. 1963;112:583-9.
22. Arnold R, Humbert B, Werchau H, Gallati H, Konig W. Interleukin-8, interleukin-6, and soluble tumor necrosis factor receptor type release from a human pulmonary epithelial cell line (A549) exposed to respiratory syncytial virus. Immunology 1994;82:126-33.
23. Fiedler M, Wernk-Dollries K, Stark J. Respiratory syncytial virus increases IL-8 gene expression and protein release in A549 cells. Am J Physiol 1995;269:L865-72.
24. Elias J, Wu Y, Zheng T, Panettieri R. Cytokine-and virus-stimulated airway smooth muscle cells produce IL-11 and other IL-6 cytokines. Lung Cell Mol Physiol 1997;17:L648-55.
25. Einarsson O, Geba G, Panuska J, Zhu Z, Landry M, Elias J. Asthma-associated viruses specifically induce lung stromal cells to produce interleukin-11, a mediator of airways hypersensitivity. Chest 1995;107:132S-133S.
26. Konig B, Krusat T, Streckert H, Konig W. IL-8 release from human neutrophils by the respiratory syncytial virus is independent of viral replication. J Leukoc Biol 1996;60:253-60.
27. Noah T, Henderson F, Wortman I, et al. Nasal cytokine production in viral acute upper respiratory infection of childhood. J Infect Dis 1995;171:584-92.
28. Matsuda K, Tsutsumi H, Okamoto Y, Chiba C. Development of interleukin 6 and tumor necrosis factor alpha activity in nasopharyngeal secretions of infants and children during infection with respiratory syncytial virus. Clin Diag Lab Immun 1995;2:322-4.
29. Lindgren C, Grogaard J. Reflex apnoea response and inflammatory mediators in infants with respiratory tract infection. Acta Paediatr 1996;85:798-803.
30. Aherne W, Bird T, Court S, Gardner P, McQuillin J. Pathological changes in virus infections of the lower respiratory tract in children. J Clin Pathol 1970;23:7-18.
31. Everard M, Swarbrick A, Wrightham M, et al. Analysis of cells obtained by bronchial lavage of infants with respiratory syncytial virus infection. Arch Dis Child 1994;71:428-32.
32. Malley R, DeVincenzo J, Ramilo O, et al. Reduction of respiratory syncytial virus (RSV) in tracheal aspirates in intubated infants by use of humanized monoclonal antibody to RSV F protein. J Infect Dis 1998;178:1555-61.
33. Darlow B, Sluis K, Inder T, Winterbourn C. Endotracheal suctioning of the neonate: comparison of two methods as a source of mucus material for research. Pediatr Pulmonol 1997;23:217-21.
34. Benfield T, Vestbo J, Junge J, Nielsen T, Jensen A, Lundgren J. Prognostic value of interleukin-8 in AIDS-associated Pneumocystis carinii pneumonia. Am J Respir Crit Care Med 1995;151:1058-62.
35. Baughman R, Gunther K, Rashkin M, Keeton D, Pattishall E. Changes in the inflammatory response of the lung during acute respiratory distress syndrome: prognostic indicators. Am J Respir Grit Care Med 1996;154:76-81.
36. Boutten A, Dehoux M, Seta N, et al. Compartmentalized IL-8 and elastase release within the human lung in unilateral pneumonia. Am J Respir Crit Care Med 1996;153:336-42.
37. Cheng P, Boat T, Costa D. Differential effects of ozone on lung epithelial lining fluid volume on protein content. Exp Lung Res 1995;21:351-65.