Correlation of clonal T cell expansion with disease activity in systemic lupus erythematosus

International Immunology

Volumn 9, Issue 4, 1997, Pages 547-554

  Mato, Takashi ^a   Masuko, Kayo ^b   Misaki, Yoshikata ^a   Hirose, Naoto ^a   Ito, Koji ^a   Takemoto, Yuji ^c   Izawa, Katsuhiko ^c   Yamamori, Shunji ^c   Kato, Tomohiro ^b   Nishioka, Kusuki ^b   Yamamoto, Kazuhiko ^d  

^a UNIVERSITY OF TOKYO   (Japan)

^b ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c LSI MEDIENCE CORPORATION   (Japan)

^d KYUSHU UNIVERSITY   (Japan)

Author keywords

RT PCR SSCP; T cell clonality; TCR

Indexed keywords

ADULT; ARTICLE; BETA CHAIN; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; FEMALE; HUMAN; IMMUNOPATHOGENESIS; LYMPHOCYTE CLONE; MALE; PATHOGENESIS; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; REMISSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ADOLESCENT; ADULT; CLONE CELLS; FEMALE; HUMANS; KINETICS; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; PERICARDITIS; PLEURISY; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; T-LYMPHOCYTE SUBSETS;

EID: 8244230514     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/9.4.547     Document Type: Article

References (45)

1. Theofilopoulos, A. N., Prund'homme, G. J. and Dixon, F. J. 1985. Autoimmune aspects of systemic lupus erythematosus. Concepts Immunopathol. 1:190.
2. Steinberg, A. D. 1984. Modern concepts of systemic lupus erythematosus. Prog. Clin. Rheumatol. 1:1.
3. Hardin, J. A. 1986. The lupus autoantigens and the pathogenesis of systemic lupus erythematosus. Arthritis Rheum. 29:457.
4. Kuntz, M. M., Innes, J. B. and Weksler, M. E. 1979. The cellular basis of the impaired autologous mixed lymphocyte reaction in patients with systemic lupus erythematosus. J. Clin. Invest. 63:151.
5. Kohsaka, H., Yamamoto, K., Fujii, H., Miura, H., Miyasaka, N., Nishioka, K. and Miyamoto, T. 1990. Fine epitope mapping of the human SS-B/La protein. J. Clin. Invest. 85:1566.
6. Kato, T., Yamamoto, K., Takeuti, H., Okubo, M., Hara, E., Nakada, S., Oda, K., Ito, K. and Nishioka, K. 1993. Identification of a universal B cell epitope on DNA topoisomerase I, an autoantigen associated with scleroderma. Arthritis Rheum. 36:1580.
7. Misaki, Y., Yamamoto, K., Yanagi, Y., Miura, H., Ichijo, H., Kato, T., Mato, T., Welling-Wester, S., Nishioka, K. and Ito, K. 1993. B cell epitope on the U1 snRNP-C autoantigen contains a sequence similar to that of the herpes simplex virus protein. Eur. J. Immunol. 23:1064.
8. Hamilton, M. E. and Winfield, J. B. 1979. Tg cells in systemic lupus erythematosus. Arthritis Rheum. 22:1.
9. Posnett, D. N., Gottlieb, A., Bussel, J. B., Friedman, S. M., Chiorazzi, N., Li, Y., Szabo, P., Farid, N. R. and Robinson, M. A. 1988. T cell antigen receptors in autoimmunity. J. Immunol. 141:1963.
10. Harrison, L. C., Honeyman, M. C., DeAizpurua, H. J., Schmidli, R. S., Colman, P. G., Tait, B. D. and Cram, D. S. 1993. Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes. Lancet 341:1365.
11. Okubo, M, Yamamoto, K., Mato, T., Matsura, N., Nishimaki, T., Kasukawa, R., Ito, K., Mizushima, Y. and Nishioka, K. 1993. Detection and epitope analysis of autoantigen-reactive T cells to the U1-small nuclear ribonucleoprotein A protein in autoimmune disease patients. J. Immunol. 151:1108.
12. Crow, M. K., DelGiudice-Asch, G., Zehetbauer, J. B., Lawson, J. L., Brot, N., Weissbach, H. and Elkon, K. B. 1994. Autoantigen-specific T cell proliferation induced by the ribosomal P2 protein in patients with systemic lupus erythematosus. J. Clin. Invest. 94:345.
13. Davis, M. M. and Bjorlman, P. J. 1988. T-cell antigen receptor genes and T-cell recognition. Nature 334:395.
14. Chothia, C., Boswell, D. R. and Lesk, A. M. 1988. The outline structure of the T-cell αβ receptor. EMBO J. 7:3745.
15. Brenner, M. B., Trowbridge, I. S., McLean, J. and Strominger, J. L. 1984. Identification of shared antigenic determinants of the putative human T lymphocyte antigen receptor. J. Exp. Med. 160:541.
16. Fabbi, M., Acuto, O., Bensussan, A., Poole, C. B. and Reinherz, E. L. 1985. Production and characterization of antibody probes directed at constant regions of the alpha and beta subunit of the human T cell receptor. Eur. J. Immunol. 15:821
17. Brener, M. B., McLean, J., Scheft, H., Warnke, R. A., Jones, N. and Strominger, J. L. 1987. Characterization and expression of the human αβ T cell receptor by using a framework monoclonal antibody. J. Immunol. 138:1502.
18. β segment that imparts reactivity to a class II major histocompatibility complex product. Cell 49:263.
19. Davis, T. F., Martin, A. and Concepcin, E. S. S. 1991. Evidence of limited variability of antigen receptors on intrathyroidal T cells in autoimmune thyroid disease. New Engl. J. Med. 325:238.
20. Moebius, U., Manns, M. and Hess, G. 1990. T cell receptor gene rearrangements of T lymphocytes infiltrating the liver in chronic active hepatitis B and primary cirrhosis (PBC). Eur. J. Immunol. 2:889.
21. Wucherpfennig, K. W. and Newcombe, J. 1992. T cell receptor Vα-Vβ repertoire and cytokine gene expression in active multiple sclerosis lesions. J. Exp. Med. 175:993.
22. Ben-Nun. A., Liblau, R. S. and Cohen, L. 1991. Restricted T cell receptor V beta gene usage by myelin basic protein-specific T-cell clones in multiple sclerosis. Proc. Natl Acad. Sci. USA 88:2466.
23. Ikeda, Y., Masuko, K., Nakai, Y., Kato, T., Hasanuma, T., Yoshino, S., Mizushima, Y., Nishioka, K. and Yamamoto, K. 1996. High frequencies of identical T cell clonotypes in synovial tissues of rheumatoid arthritis patients suggest the occurrence of common antigen-driven immune responses. Arthritis Rheum. 39:446.
24. Yamamoto, K., Sakoda, H., Nakajima, T., Kato. T., Okubo, M., Dohi, M., Mizushima, Y, Ito, K. and Nishioka, K. 1992. Accumulation of Multiple T cell clonotypes in the synovial lesions of multiple T cell clonotypes in the synovial lesions of patients with rheumatoid arthritis revealed by a novel clonality analysis. Int. Immunol. 4:1219.
25. Dohi, M., Yamamoto, K., Masuko, K., Ikeda, Y., Matsuzaki, G., Sugiyama, H., Suko, M., Okudaira, H., Misushima, Y., Nishioka, K. and Ito, K. 1944. Accumulation of multiple T cell clonotypes in lungs of healthy individuals and patients with pulmonary sarcoidosis. J. Immunol. 152:1983.
26. Masuko, K., Kato, T., Ikeda, Y., Okubo, M., Mizushima, Y., Nishioka, K. and Yamamoto, K. 1994. Dynamic change of accumulated T cell clonotypes during antigenic stimulation in vivo and in vitro. Int. Immunol. 6:1959.
27. Yamamoto, K., Masuko, K., Takahashi, S., Ikeda, Y., Kato, T., Mizushima, Y., Hayashi, K. and Nishioka, K. 1995. Accumulation of distinct T cell clonotypes in human solid tumors. J. Immunol. 154:1804.
28. Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B. and Ehrich, H. A. 1988. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239:487.
29. Orita, M., Suzuki, Y., Sekiya, T. and Hayashi, K. 1989. Rapid and sensitive detection of point mutations and DNA polymorphism using the polymerase chain reaction. Genomics 5:874.
30. Tan, E. M., Cohen, A. S. and Fries, J. F. 1982. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 25:1271.
31. Chomczynski, P. and Sacchi, N. 1987. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156.
32. Choi, Y., Kotzin, B., Herron, L., Callahan, J., Marrack, P. and Kappler, J. 1989. Interaction of Staphylococcus aureus toxin 'superantigens' with human T cells. Proc. Natl Acad. Sci. USA 96:8941.
33. Horwits, A. D. 1993 Abnormalities in T lymphocytes. In Wallace D. J. and Hahn, B. H., eds, Dubois's Lupus Erythematosus, 4th edn, p. 83. Lea & Febiger, Philadelphia.
34. Desai-Mehta, A., Mao, C., Rajafopalan, S., Robinson, T. and Data, S. K. 1995. Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus. J. Clin. Invest 95:531
35. Huffman, R. W., Yoshimoto, T., Sharp, G. C., Lee, D. R., Hill, D. L., Kaneoka, H. and Caldwell, C. W. 1993. Human T cell clones reactive against U-Small nuclear ribonucleoprotein autoantigens from connective tissue disease patients and healthy individuals. J. Immunol. 157:6460
36. Okubo, M., Kurokawa, M., Ohto, H., Nishimaki, T., Nishioka, K., Kasukawa, R. and Yamamoto, K. 1994. Clonotype analysis of peripheral blood T cells and autoantigen-reactive T cells from patients with mixed connective tissue disease. J. Immunol. 153:3784.
37. Rosenthal, C. J. and Franklin, E. C. 1975. Depression of cellular mediated immunity in systemic lupus erythematosus. Relation to disease activity. Arthritis Rheum. 18:207.
38. Masuko, K., Kato, S., Hagihara, M., Tsuchida, F., Takemoto, Y., Izawa, K., Kato, T., Yamamori, S., Mizushima, Y., Nishioka, K., Tsuji, K. and Yamamoto, K. 1996. Stable clonal expansion of T cells induced by bone marrow transplantation. Blood 87:789.
39. + T cell clones during normal pregnancy. Eur. J. Immunol. 26:834.
40. Ikeda, Y., Masuko, K., Nakai, Y., Kato, T., Hasanuma, T. Yoshino, S., Mizushima, Y., Nishioka, K. and Yamamoto, K. 1996. High frequencies of identical T cell clonotypes in synovial tissues of rheumatoid arthritis patients suggest the occurrence of common antigen-driven immune responses. Arthritis Rheum. 39:446.
41. Komagata, Y., Masuko, K., Tashiro, F., Kato, T., Ikuta, K., Nishioka, K., Ito, K., Miyazaki, J. and Yamamoto, K. 1996. Clonal prevalence of T cells infiltration into the pancreas of prediabetic non-obese diabetic mice. Int. Immunol. 8:807
42. Glinski, W., Gershwin, M. E. and Steinberg, A. D. 1976. Study of lymphocyte subpopulation in normal humans and patients with SLE by fractionation of peripheral blood lymphocyte on a discontinuous Ficoll gradient. J. Clin. Invest. 57:604.
43. Sakane, T., Steinberg, A. D., Arnett, F. C., Reinertsen, J. L. and Green, I. 1979. Studies of immune functions of patients with systemic lupus erythematosus. III. Characterization of lymphocytes subpopulation responsible for defective autologous mixed lymphocyte reactions. Arthritis Rheum. 22:770
44. Kuntz, M. M., Innes J. B. and Weksler, M. E. 1979. The cellular basis of the impaired autologous mixed lymphocyte reaction in patients with systemic lupus erythematosus. J. Clin. Invest. 63:151.
45. Rowley, D. A. and Stach, R. M. 1993. A first or dominant immunization. I. suppression of simultaneous cytolytic T cell responses to unrelated alloantigens. J. Exp. Med. 178:835.