메뉴 건너뛰기




Volumn 79, Issue 2, 1996, Pages 171-181

Intrathymic injection of polynucteosomes delays autoantibody production in BXSB mice

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; DNA ANTIBODY; T LYMPHOCYTE ANTIGEN; ANTINUCLEAR ANTIBODY; DNA; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 0029664982     PISSN: 00901229     EISSN: None     Source Type: Journal    
DOI: 10.1006/clin.1996.0064     Document Type: Article
Times cited : (15)

References (54)
  • 1
    • 0002902950 scopus 로고
    • Anti-histone antibodies
    • (R. G. Lahita, Ed.), 2nd ed., Wiley, New York
    • Rubin, R. L. Anti-histone antibodies. In "Systemic Lupus Erythematosus" (R. G. Lahita, Ed.), 2nd ed., pp. 247-271, Wiley, New York, 1992.
    • (1992) Systemic Lupus Erythematosus , pp. 247-271
    • Rubin, R.L.1
  • 2
    • 0022273898 scopus 로고
    • Murine models of systemic lupus erythematosus
    • Theofilopoulos, A. N., and Dixon, F. J., Murine models of systemic lupus erythematosus. Adv. Immunol. 37, 269-390, 1985.
    • (1985) Adv. Immunol. , vol.37 , pp. 269-390
    • Theofilopoulos, A.N.1    Dixon, F.J.2
  • 3
    • 0028869486 scopus 로고
    • The basis of autoimmunity. I. Mechanisms of aberrant self-recognition
    • Theofilopoulos, A. N., The basis of autoimmunity. I. Mechanisms of aberrant self-recognition. Immunol. Today 16, 90-98, 1995
    • (1995) Immunol. Today , vol.16 , pp. 90-98
    • Theofilopoulos, A.N.1
  • 4
    • 0021965670 scopus 로고
    • Successful treatment of autoim
    • Wofsy, D., and Seaman, W. E., Successful treatment of autoimJ. Exp. Med. 161, 378-391, 1985.
    • (1985) J. Exp. Med. , vol.161 , pp. 378-391
    • Wofsy, D.1    Seaman, W.E.2
  • 5
    • 0023896085 scopus 로고
    • + T cells to lymphoproliferation and autoantibody production in MRL-lpr/lpr mice
    • + T cells to lymphoproliferation and autoantibody production in MRL-lpr/lpr mice. J. Exp. Med. 167, 1713-1718, 1988.
    • (1988) J. Exp. Med. , vol.167 , pp. 1713-1718
    • Santoro, T.J.1    Portanova, J.P.2    Kotzin, B.L.3
  • 6
    • 0028235184 scopus 로고
    • T-B collaboration for autoantibody production in lpr mice is cognate and MHC-restricted
    • Sobel, E. S., Kakkanaiah, V. N., Kakkanaiah, M., Cheek, R. L., Cohen, P. L., and Eisenberg, R. L., T-B collaboration for autoantibody production in lpr mice is cognate and MHC-restricted. J. Immunol. 152, 6011-6016, 1994.
    • (1994) J. Immunol. , vol.152 , pp. 6011-6016
    • Sobel, E.S.1    Kakkanaiah, V.N.2    Kakkanaiah, M.3    Cheek, R.L.4    Cohen, P.L.5    Eisenberg, R.L.6
  • 7
    • 0027245507 scopus 로고
    • Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen
    • Burlingame, R. W., Rubin, R. L., Balderas, R. S., and Theofilopoulos, A. N., Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen. J. Clin. Invest. 91, 1687-1695, 1993.
    • (1993) J. Clin. Invest. , vol.91 , pp. 1687-1695
    • Burlingame, R.W.1    Rubin, R.L.2    Balderas, R.S.3    Theofilopoulos, A.N.4
  • 8
    • 0027477318 scopus 로고
    • Nucleosome: A major immunogen for pathogenic autoantibody-inducing T cells of lupus
    • Mohan, C., Adams, S., Stanik, V., and Datta, S. K., Nucleosome: A major immunogen for pathogenic autoantibody-inducing T cells of lupus. J. Exp. Med 177, 1367-1381, 1993.
    • (1993) J. Exp. Med , vol.177 , pp. 1367-1381
    • Mohan, C.1    Adams, S.2    Stanik, V.3    Datta, S.K.4
  • 9
    • 0024376399 scopus 로고
    • T cell tolerance to self antigens in New Zealand hybridmice with lupus-like disease
    • Kotzin, B. L., Kappler, J. W., Marrack, P. C., and Herron, L. R., T cell tolerance to self antigens in New Zealand hybridmice with lupus-like disease. J. Immunol. 143, 89-94, 1989
    • (1989) J. Immunol. , vol.143 , pp. 89-94
    • Kotzin, B.L.1    Kappler, J.W.2    Marrack, P.C.3    Herron, L.R.4
  • 10
    • 0025572233 scopus 로고
    • T-cell receptor V β repertoire expression in murine models of SLE
    • Singer, P. A., and Theofilopoulos, A. N,. T-cell receptor V β repertoire expression in murine models of SLE. Immunol. Rev. 118, 103-127, 1990.
    • (1990) Immunol. Rev. , vol.118 , pp. 103-127
    • Singer, P.A.1    Theofilopoulos, A.N.2
  • 11
    • 0026531128 scopus 로고
    • Transgenic T cell receptor interactions in the lymphoproliferative and autoimmune syndromes of Ipr and gldmutant mice
    • Sidman, C. L., Marshal, J. D., and Von Boehmer, H., Transgenic T cell receptor interactions in the lymphoproliferative and autoimmune syndromes of Ipr and gldmutant mice. Eur. J. Immunol. 22, 499-504, 1992
    • (1992) Eur. J. Immunol. , vol.22 , pp. 499-504
    • Sidman, C.L.1    Marshal, J.D.2    Von Boehmer, H.3
  • 12
    • 0028485743 scopus 로고
    • The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
    • Singer, G. G., and Abbas, A. K., The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1, 365-371, 1994
    • (1994) Immunity , vol.1 , pp. 365-371
    • Singer, G.G.1    Abbas, A.K.2
  • 13
    • 0026060648 scopus 로고
    • Defect in negativeselection in lpr donor-derived T cells differentiating in non-lpr host thymus
    • Matsumoto, K., Yoshikai, Y., Asano, T., Himeno, K., Iwasaki, A., and Nomoto, K., Defect in negativeselection in lpr donor-derived T cells differentiating in non-lpr host thymus. J. Exp. Med. 173, 127-136, 1991
    • (1991) J. Exp. Med. , vol.173 , pp. 127-136
    • Matsumoto, K.1    Yoshikai, Y.2    Asano, T.3    Himeno, K.4    Iwasaki, A.5    Nomoto, K.6
  • 14
    • 0025873567 scopus 로고
    • Abnormal thymocyte develpment and production of autoreactive T cells in T cell receptor transgenic autoimmune mice
    • Zhou, Bluethmann, T. H., Eldridge, J., Brockhaus, M., Berry, K., and Mountz, J. D., Abnormal thymocyte develpment and production of autoreactive T cells in T cell receptor transgenic autoimmune mice. J. Immunol. 147, 466-474, 1991.
    • (1991) J. Immunol. , vol.147 , pp. 466-474
    • Zhou1    Bluethmann, T.H.2    Eldridge, J.3    Brockhaus, M.4    Berry, K.5    Mountz, J.D.6
  • 15
    • 0027266844 scopus 로고
    • Studies of T cell deletion and T cell anergy following in vivo administration of SEB to normal and lupus-prone mice
    • Scott, D. E., Kisch, W. J., and Steinberg, A. D., Studies of T cell deletion and T cell anergy following in vivo administration of SEB to normal and lupus-prone mice. J. Immunol. 150, 664-672, 1993
    • (1993) J. Immunol. , vol.150 , pp. 664-672
    • Scott, D.E.1    Kisch, W.J.2    Steinberg, A.D.3
  • 16
    • 0027314703 scopus 로고
    • Mature T cells of autoimmune lpr/lpr mice have a defect in antigen stimulated suicide
    • Russell, J. H., Rush, B., Weaver, C., and Wang, R. D., Mature T cells of autoimmune lpr/lpr mice have a defect in antigen stimulated suicide. Proc. Natl. Acad. Sci. USA 90, 4409-4413, 1993
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4409-4413
    • Russell, J.H.1    Rush, B.2    Weaver, C.3    Wang, R.D.4
  • 19
    • 0014425694 scopus 로고
    • Immune response to a soluble protein antigen in NZB mice
    • Weir, D. M. and McBride, W., Immune response to a soluble protein antigen in NZB mice Nature 219, 1276-1277, 1969
    • (1969) Nature , vol.219 , pp. 1276-1277
    • Weir, D.M.1    McBride, W.2
  • 20
    • 0026695423 scopus 로고
    • Prevention of autoimmune diabetes in the BB rat by intrathymic islet transplantation at birth
    • Posselt, A. M., Barker, C. F., Friedman, A. L., and Naji, A., Prevention of autoimmune diabetes in the BB rat by intrathymic islet transplantation at birth Science 256, 1321-1324, 1992
    • (1992) Science , vol.256 , pp. 1321-1324
    • Posselt, A.M.1    Barker, C.F.2    Friedman, A.L.3    Naji, A.4
  • 21
    • 0026545730 scopus 로고
    • Intrathymic islet cell transplantation reduces beta-cell autoimmunity and prevents diabetes in NOD/Lt mice
    • Gerling, I. C., Serreze, D. V., Christianson, S. W., and Leiter, E. H., Intrathymic islet cell transplantation reduces beta-cell autoimmunity and prevents diabetes in NOD/Lt mice Diabetes 41, 1672-1676, 1992
    • (1992) Diabetes , vol.41 , pp. 1672-1676
    • Gerling, I.C.1    Serreze, D.V.2    Christianson, S.W.3    Leiter, E.H.4
  • 22
    • 0026712314 scopus 로고
    • Induction of tolerance to autoimmune diabetes with islet antigens
    • Herold, K. C., Montag, A. G., and Buckingham, F., Induction of tolerance to autoimmune diabetes with islet antigens. J. Exp. Med. 176, 1107-1114, 1992
    • (1992) J. Exp. Med. , vol.176 , pp. 1107-1114
    • Herold, K.C.1    Montag, A.G.2    Buckingham, F.3
  • 24
    • 0027908753 scopus 로고
    • Immune response to glutamic acid decarboxylase correlates with insulitisin non-obese diabeticmice
    • Tisch, R., Yang, X-D., Singer, S. M., Liblau, R. S., Fugger, L., and McDevitt, H. O., Immune response to glutamic acid decarboxylase correlates with insulitisin non-obese diabeticmice Nature 366, 72-75, 1993
    • (1993) Nature , vol.366 , pp. 72-75
    • Tisch, R.1    Yang, X.-D.2    Singer, S.M.3    Liblau, R.S.4    Fugger, L.5    McDevitt, H.O.6
  • 25
    • 0027255487 scopus 로고
    • Acquired tolerance to experiof myelin basic protein or its major encephalitogeinc peptide
    • Khoury, S. J., Sayegh, M. H., Hancock, W. W., Gallon, L., Carpenter, C. B., and Weiner, H. L., Acquired tolerance to experiof myelin basic protein or its major encephalitogeinc peptide. J. Exp. Med. 178, 559-566, 1993.
    • (1993) J. Exp. Med. , vol.178 , pp. 559-566
    • Khoury, S.J.1    Sayegh, M.H.2    Hancock, W.W.3    Gallon, L.4    Carpenter, C.B.5    Weiner, H.L.6
  • 26
    • 0028089783 scopus 로고
    • Immunological tolerance to a defined myelin basic protein antigen administered intrathymically
    • Goss, J. A., Nakafusa, Y., Roland, C. R., Hickey, W. F., and Flye, M. W., Immunological tolerance to a defined myelin basic protein antigen administered intrathymically. J. Immunol. 153, 3890-3898, 1994
    • (1994) J. Immunol. , vol.153 , pp. 3890-3898
    • Goss, J.A.1    Nakafusa, Y.2    Roland, C.R.3    Hickey, W.F.4    Flye, M.W.5
  • 27
    • 0027220205 scopus 로고
    • An autoimmune disease with multiple molecular targets abrogated by the transgeneic expression of a single autoantigen in the thymus
    • Alderuccio, F., Toh, B-H., Tan, S-S., Gleeson, P. A., and van Driel, I. R., An autoimmune disease with multiple molecular targets abrogated by the transgeneic expression of a single autoantigen in the thymus. J. Exp. Med. 178, 419-426, 1993.
    • (1993) J. Exp. Med. , vol.178 , pp. 419-426
    • Alderuccio, F.1    Toh, B.-H.2    Tan, S.-S.3    Gleeson, P.A.4    Van Driel, I.R.5
  • 28
    • 0027092408 scopus 로고
    • Induction of specific unresponsiveness (tolerance) to skin allografts by intrathymic donor-specific splenocyte injection in antilymphocyte serum-treated mice
    • Ohzato, H., and Monaco, A. P., Induction of specific unresponsiveness (tolerance) to skin allografts by intrathymic donor-specific splenocyte injection in antilymphocyte serum-treated mice Transplantation 54, 1090-1095, 1992
    • (1992) Transplantation , vol.54 , pp. 1090-1095
    • Ohzato, H.1    Monaco, A.P.2
  • 29
    • 0025783963 scopus 로고
    • Drug-induced anti-histone autoantibodies display two patterns of reactivity with substructures of chromatin
    • Burlingame, R. W., and Rubin, R. L., Drug-induced anti-histone autoantibodies display two patterns of reactivity with substructures of chromatin. J. Clin. Invest. 88, 680-690, 1991.
    • (1991) J. Clin. Invest. , vol.88 , pp. 680-690
    • Burlingame, R.W.1    Rubin, R.L.2
  • 30
    • 0025017306 scopus 로고
    • Spectropolarimetric analysis of the core histone octamer and its subunits
    • Godfrey, J. E., Baxevanis, A. D., and Moudrianakis, E. N., Spectropolarimetric analysis of the core histone octamer and its subunits. Biochemistry 29, 965-972, 1982.
    • (1982) Biochemistry , vol.29 , pp. 965-972
    • Godfrey, J.E.1    Baxevanis, A.D.2    Moudrianakis, E.N.3
  • 31
    • 0025153738 scopus 로고
    • Thymic selection defines multiple T cell receptor Vβ repertoire phenotypes at the CD4/CD8 subset level
    • Singer PA, Balderas, R. S., and Theofilopoulos, A. N., Thymic selection defines multiple T cell receptor Vβ repertoire phenotypes at the CD4/CD8 subset level. EMBO J. 9, 3641-3648, 1990.
    • (1990) EMBO J. , vol.9 , pp. 3641-3648
    • Singer, P.A.1    Balderas, R.S.2    Theofilopoulos, A.N.3
  • 32
    • 0001513802 scopus 로고
    • DNA strand brakes occurring during apoptosis: Their early in situ detection by the terminal deoxynucleotydyl transferase and nick translation assays and prevention by serine protease inhibitions
    • Gorczyea, W., Bruno, S., Darzynkiewicz, R. J., Gong, J., and Darzynkiewicz, Z., DNA strand brakes occurring during apoptosis: Their early in situ detection by the terminal deoxynucleotydyl transferase and nick translation assays and prevention by serine protease inhibitions. Int. J. Oncol. 1, 639-645, 1992.
    • (1992) Int. J. Oncol. , vol.1 , pp. 639-645
    • Gorczyea, W.1    Bruno, S.2    Darzynkiewicz, R.J.3    Gong, J.4    Darzynkiewicz, Z.5
  • 33
    • 0028054017 scopus 로고
    • T-cell apoptosis detected in situ during positive and negative selection in the thymus
    • Surh, C. D., and Sprent, J., T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 372, 100-103, 1994.
    • (1994) Nature , vol.372 , pp. 100-103
    • Surh, C.D.1    Sprent, J.2
  • 35
    • 0026343952 scopus 로고
    • Junctional region sequences of T-cell receptor beta-chain genes expressed by pathomice: Possible selection by cationic autantigens
    • Adams, S., Leblanc, P., and Datta, S. K., Junctional region sequences of T-cell receptor beta-chain genes expressed by pathomice: Possible selection by cationic autantigens. Proc. Natl. Acad. Sci. USA 88, 11271-11275, 1991
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 11271-11275
    • Adams, S.1    Leblanc, P.2    Datta, S.K.3
  • 36
    • 0022573806 scopus 로고
    • The lupus autoantigens and the pathogenesis of systemic lupus erythematosus
    • Hardin, J. A., The lupus autoantigens and the pathogenesis of systemic lupus erythematosus Arthritis Rheum 29, 457-460, 1986.
    • (1986) Arthritis Rheum , vol.29 , pp. 457-460
    • Hardin, J.A.1
  • 37
    • 0024518559 scopus 로고
    • Antinuclear antibodies Diagnosticmarkersfor auto-immune diseases and probes for cell biology
    • Tan, E. M., Antinuclear antibodies Diagnosticmarkersfor auto-immune diseases and probes for cell biology. Adv. Immunol. 44, 93-151, 1989
    • (1989) Adv. Immunol. , vol.44 , pp. 93-151
    • Tan, E.M.1
  • 38
    • 0027166935 scopus 로고
    • Determinant spreading and the dynamics of the autoimmune T-cell repertoire
    • Lehmann, P. V., Sercarz, E. E., Forsthuber, T., Dayan, C. V., and Gammon, G., Determinant spreading and the dynamics of the autoimmune T-cell repertoire. Immunol. Today 14, 203-208, 1993.
    • (1993) Immunol. Today , vol.14 , pp. 203-208
    • Lehmann, P.V.1    Sercarz, E.E.2    Forsthuber, T.3    Dayan, C.V.4    Gammon, G.5
  • 39
    • 0027142993 scopus 로고
    • Role of intermolecular/intrastructural B- and T-cell determinants in diversification of autoantibodies to ribonucleoprotein particles
    • Fatenegjad, S., Mamula, M. J., and Craft, J., Role of intermolecular/intrastructural B- and T-cell determinants in diversification of autoantibodies to ribonucleoprotein particles. Proc. Natl. Acad. Sci. USA 90, 12010-12014, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 12010-12014
    • Fatenegjad, S.1    Mamula, M.J.2    Craft, J.3
  • 40
    • 0027198114 scopus 로고
    • Thymicrecognition of class 11 major histocompatibility complex all opeptides induces donor-specific unresponsiveness to renal allografts
    • Sayegh, M. H., Penco, N., Imberti, O., Hancock, W. W., Carpenter, C. B., and Remuzzi, G., Thymicrecognition of class 11 major histocompatibility complex all opeptides induces donor-specific unresponsiveness to renal allografts. Transplantation 56, 461-465, 1993.
    • (1993) Transplantation , vol.56 , pp. 461-465
    • Sayegh, M.H.1    Penco, N.2    Imberti, O.3    Hancock, W.W.4    Carpenter, C.B.5    Remuzzi, G.6
  • 41
    • 0028210383 scopus 로고
    • T cell receptor alpha-chain repertoire of pathogenic autoantibody-inducing T cells in lupus mice
    • Mao, C., Osman, G. E., Adams, S., and Datta, S. K. T cell receptor alpha-chain repertoire of pathogenic autoantibody-inducing T cells in lupus mice. J. Immunol. 152, 1462-1470, 1994.
    • (1994) J. Immunol. , vol.152 , pp. 1462-1470
    • Mao, C.1    Osman, G.E.2    Adams, S.3    Datta, S.K.4
  • 42
    • 0028017808 scopus 로고
    • A differential-avidity model for T-cell selection
    • Ashton-Rickardt, P. G., and Tonagawa, S., A differential-avidity model for T-cell selection. Immunol. Today 15, 362-366, 1994.
    • (1994) Immunol. Today , vol.15 , pp. 362-366
    • Ashton-Rickardt, P.G.1    Tonagawa, S.2
  • 44
    • 0028294682 scopus 로고
    • Positive and negative thymocyte selection induced by different concentrations of a single peptide
    • Sebzda, E., Wallace, V. A., Mayer, J., Yeung, R. S. M., Mak, T. W., and Ohashi, P. S., Positive and negative thymocyte selection induced by different concentrations of a single peptide Science 263, 1615-1618, 1994.
    • (1994) Science , vol.263 , pp. 1615-1618
    • Sebzda, E.1    Wallace, V.A.2    Mayer, J.3    Yeung, R.S.M.4    Mak, T.W.5    Ohashi, P.S.6
  • 45
    • 0028376427 scopus 로고
    • Abnormal antigen receptor-initiated signal transduction in lpr T lymphocytes
    • Altman, A., Abnormal antigen receptor-initiated signal transduction in lpr T lymphocytes. Semin. immunol. 6, 9-18, 1994.
    • (1994) Semin. Immunol. , vol.6 , pp. 9-18
    • Altman, A.1
  • 46
    • 0028324236 scopus 로고
    • Maturational changes in CD4+ cell subsets and lymphokine production in BXSB mice
    • Chu, E. B., Hobbes, D. N., Hobbs, M. V., and Weigle, W. O., Maturational changes in CD4+ cell subsets and lymphokine production in BXSB mice. J. Immunol. 152, 4129-4138, 1994.
    • (1994) J. Immunol. , vol.152 , pp. 4129-4138
    • Chu, E.B.1    Hobbes, D.N.2    Hobbs, M.V.3    Weigle, W.O.4
  • 47
    • 0028410566 scopus 로고
    • Kinetics and affinity of reactions between and antigen-specific T cell receptor and peptide-MHC complexes
    • Sykulev, Y., Brunmark, A., Jackson, M., Cohen, R. J., Peterson, P. A., and Eisen, H. N., Kinetics and affinity of reactions between and antigen-specific T cell receptor and peptide-MHC complexes. Immunity 1, 15-22, 1994.
    • (1994) Immunity , vol.1 , pp. 15-22
    • Sykulev, Y.1    Brunmark, A.2    Jackson, M.3    Cohen, R.J.4    Peterson, P.A.5    Eisen, H.N.6
  • 48
    • 0025836514 scopus 로고
    • Roles of multiple accessory molecules in T-cell activation: Bilateral interplay of adhesion and costimulation
    • van Seventer, G. A., Shimizu, Y., and Shaw, S., Roles of multiple accessory molecules in T-cell activation: Bilateral interplay of adhesion and costimulation. Curr. Opin. Immunol. 3, 294-303, 1991.
    • (1991) Curr. Opin. Immunol. , vol.3 , pp. 294-303
    • Van Seventer, G.A.1    Shimizu, Y.2    Shaw, S.3
  • 49
    • 0024428816 scopus 로고
    • How someT cells escape tolerance induction
    • Gammon, G., and Sercarz, E., How someT cells escape tolerance induction Nature 342, 183-185, 1989.
    • (1989) Nature , vol.342 , pp. 183-185
    • Gammon, G.1    Sercarz, E.2
  • 50
    • 0014433278 scopus 로고
    • Mode of action for anti-lymphocyte serum
    • Leuchars, E., Wallis, V. J., and Davies, A. J. S., Mode of action for anti-lymphocyte serum. Nature 219, 1325-1328, 1968.
    • (1968) Nature , vol.219 , pp. 1325-1328
    • Leuchars, E.1    Wallis, V.J.2    Davies, A.J.S.3
  • 51
    • 0025729604 scopus 로고
    • An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity
    • Sobel, E. S., Katagiri, T., Katagiri, K., Morris, S. C., Cohen, P. L., and Eisenberg, R. A., An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity. J. Exp. Med. 173, 1441-1449, 1991.
    • (1991) J. Exp. Med. , vol.173 , pp. 1441-1449
    • Sobel, E.S.1    Katagiri, T.2    Katagiri, K.3    Morris, S.C.4    Cohen, P.L.5    Eisenberg, R.A.6
  • 52
    • 0023204355 scopus 로고
    • Systemic autoimmune disease arises from polyclonal B cell activation
    • Klinman, D. M., and Steinberg, A. D., Systemic autoimmune disease arises from polyclonal B cell activation. J. Exp. Med. 165, 1755-1760, 1987.
    • (1987) J. Exp. Med. , vol.165 , pp. 1755-1760
    • Klinman, D.M.1    Steinberg, A.D.2
  • 53
    • 0028931042 scopus 로고
    • Breakdown of B cell tolerance in a mouse model of system lupus erythematosus
    • Roark, J. H., Kuntz, C. L., Nguyen, K-A., Caton, A. J., and Erikson, J., Breakdown of B cell tolerance in a mouse model of system lupus erythematosus. J. Exp. Med. 181, 1157-1167, 1995.
    • (1995) J. Exp. Med. , vol.181 , pp. 1157-1167
    • Roark, J.H.1    Kuntz, C.L.2    Nguyen, K.-A.3    Caton, A.J.4    Erikson, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.