Sequential cleavage of poly(ADP-ribose)polymerase and appearance of a small Bax-immunoreactive protein are blocked by Bcl-X(L) and caspase inhibitors during staurosporine-induced dopaminergic neuronal apoptosis

Journal of Neurochemistry

Volumn 72, Issue 6, 1999, Pages 2456-2463

  Kim, Ji Eun ^a   Oh, Jae H ^a   Choi, Won Seok ^a   Chang, In I ^a   Sohn, Seonghyang ^b   Krajewski, Stanislaw ^c   Reed, John C ^c   O'Malley, Karen L ^d   Oh, Young J ^a  

^a Yonsei University   (South Korea)

^b Ajou University   (South Korea)

^c BURNHAM INSTITUTE   (United States)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bax; Bcl X; Caspase; MN9D cells; Poly(ADP ribose)polymerase; Staurosporine

Indexed keywords

CASPASE; CASPASE INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL X; STAUROSPORINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL SPECIFICITY; CELL TYPE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENZYME INHIBITION; GENE OVEREXPRESSION; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CASPASES; CELL LINE; CYCLOHEXIMIDE; DOPAMINE; KINETICS; MICE; NEURONS; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT PROTEINS; STAUROSPORINE; TRANSFECTION;

EID: 0033049149     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0722456.x     Document Type: Article

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