메뉴 건너뛰기




Volumn 72, Issue 6, 1999, Pages 2312-2322

Prostate apoptosis response-4 production in synaptic compartments following apoptotic and excitotoxic insults: Evidence for a pivotal role in mitochondrial dysfunction and neuronal degeneration

Author keywords

Antisense oligodeoxynucleotide; Caspase; Hydroxynonenal; Mitochondrial transmembrane potential; Protein translation; Reactive oxygen species; Staurosporine

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CASPASE; REACTIVE OXYGEN METABOLITE; STAUROSPORINE;

EID: 0033012932     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0722312.x     Document Type: Article
Times cited : (92)

References (61)
  • 2
    • 0032972922 scopus 로고    scopus 로고
    • Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice
    • Begley J. G., Duan W., Chan S., Duff K. and Mattson M. P. (1999) Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice. J. Neurochem. 72, 1030-1039.
    • (1999) J. Neurochem. , vol.72 , pp. 1030-1039
    • Begley, J.G.1    Duan, W.2    Chan, S.3    Duff, K.4    Mattson, M.P.5
  • 3
    • 0030792007 scopus 로고    scopus 로고
    • Positioning atypical protein kinase C isoforms in the UV-induced apoptotic signaling cascade
    • Berra E., Municio M. M., Sanz L., Frutos S., Diaz-Meco M. T., and Moscat J. (1997) Positioning atypical protein kinase C isoforms in the UV-induced apoptotic signaling cascade. Mol. Cell. Biol. 17, 4346-4354.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4346-4354
    • Berra, E.1    Municio, M.M.2    Sanz, L.3    Frutos, S.4    Diaz-Meco, M.T.5    Moscat, J.6
  • 4
    • 0028838282 scopus 로고
    • Excitotoxic degeneration is initiated at non-random sites in cultured rat cerebellar neurons
    • Bindokas V. P. and Miller R. J. (1995) Excitotoxic degeneration is initiated at non-random sites in cultured rat cerebellar neurons. J. Neurosci. 15, 6999-7011.
    • (1995) J. Neurosci. , vol.15 , pp. 6999-7011
    • Bindokas, V.P.1    Miller, R.J.2
  • 6
    • 0031898760 scopus 로고    scopus 로고
    • Programmed cell death and Parkinson's disease
    • Burke R. E. (1998) Programmed cell death and Parkinson's disease. Mov. Disord. 13 (Suppl. 1), 17-23.
    • (1998) Mov. Disord. , vol.13 , Issue.SUPPL. 1 , pp. 17-23
    • Burke, R.E.1
  • 8
    • 0028642274 scopus 로고
    • Calcium and excitotoxic neuronal injury
    • Choi D. W. (1994) Calcium and excitotoxic neuronal injury. Ann. NY Acad. Sci. 747, 162-171.
    • (1994) Ann. NY Acad. Sci. , vol.747 , pp. 162-171
    • Choi, D.W.1
  • 9
    • 0032146787 scopus 로고    scopus 로고
    • Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period
    • Conti A. C., Raghupathi R., Trojanowski J. Q., and McIntosh T. K. (1998) Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period. J. Neurosci. 18, 5663-5672.
    • (1998) J. Neurosci. , vol.18 , pp. 5663-5672
    • Conti, A.C.1    Raghupathi, R.2    Trojanowski, J.Q.3    McIntosh, T.K.4
  • 10
    • 0026452521 scopus 로고
    • Protein synthesis within neuronal growth cones
    • Davis L., Dou P., DeWit M., and Kater S. B. (1992) Protein synthesis within neuronal growth cones. J. Neurosci. 12, 4867-4877.
    • (1992) J. Neurosci. , vol.12 , pp. 4867-4877
    • Davis, L.1    Dou, P.2    DeWit, M.3    Kater, S.B.4
  • 11
    • 0030572696 scopus 로고    scopus 로고
    • The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C
    • Diaz-Meco M. T., Municio M. M., Frutos S., Sanchez P., Lozano J., Sanz L., and Moscat J. (1996) The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C. Cell 86, 777-786.
    • (1996) Cell , vol.86 , pp. 777-786
    • Diaz-Meco, M.T.1    Municio, M.M.2    Frutos, S.3    Sanchez, P.4    Lozano, J.5    Sanz, L.6    Moscat, J.7
  • 12
    • 0015523806 scopus 로고
    • Evidence for protein synthesis in synaptosomal membranes
    • Gilbert J. M. (1972) Evidence for protein synthesis in synaptosomal membranes. J. Biol. Chem. 247, 6541-6550.
    • (1972) J. Biol. Chem. , vol.247 , pp. 6541-6550
    • Gilbert, J.M.1
  • 13
    • 0029924284 scopus 로고    scopus 로고
    • Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid β-peptide toxicity in hippocampal neurons
    • Goodman Y., Bruce A. J., Cheng B., and Mattson M. P. (1996) Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid β-peptide toxicity in hippocampal neurons. J. Neurochem. 66, 1836-1844.
    • (1996) J. Neurochem. , vol.66 , pp. 1836-1844
    • Goodman, Y.1    Bruce, A.J.2    Cheng, B.3    Mattson, M.P.4
  • 15
    • 0031571676 scopus 로고    scopus 로고
    • Fluorometric and colorimetric detection of caspase activity associated with apoptosis
    • Gurtu V., Kain S. R., and Zhang G. (1997) Fluorometric and colorimetric detection of caspase activity associated with apoptosis. Anal. Biochem. 251, 98-102.
    • (1997) Anal. Biochem. , vol.251 , pp. 98-102
    • Gurtu, V.1    Kain, S.R.2    Zhang, G.3
  • 16
    • 0030573830 scopus 로고    scopus 로고
    • Reduction in numerical synapse density in chick (Gallus domesticus) dorsal hippocampus following transient cerebral ischaemia
    • Horner C. H., Davies H. A., Brown J., and Stewart M. G. (1996) Reduction in numerical synapse density in chick (Gallus domesticus) dorsal hippocampus following transient cerebral ischaemia. Brain Res. 735, 354-359.
    • (1996) Brain Res. , vol.735 , pp. 354-359
    • Horner, C.H.1    Davies, H.A.2    Brown, J.3    Stewart, M.G.4
  • 18
    • 0030966546 scopus 로고    scopus 로고
    • Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid β-peptide: Role of the lipid peroxidation product 4-hydroxynonenal
    • Keller J. N., Pang Z., Geddes J. W., Begley J. G., Germeyer A., Waeg G., and Mattson M. P. (1997) Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid β-peptide: role of the lipid peroxidation product 4-hydroxynonenal. J. Neurochem. 69, 273-284.
    • (1997) J. Neurochem. , vol.69 , pp. 273-284
    • Keller, J.N.1    Pang, Z.2    Geddes, J.W.3    Begley, J.G.4    Germeyer, A.5    Waeg, G.6    Mattson, M.P.7
  • 19
    • 0032100452 scopus 로고    scopus 로고
    • Rhodamine-123 staining in hematopoietic stem cells of young mice indicates mitochondrial activation rather than dye efflux
    • Kim M., Cooper D. D., Hayes S. F., and Spangrude G. J. (1998) Rhodamine-123 staining in hematopoietic stem cells of young mice indicates mitochondrial activation rather than dye efflux. Blood 91, 4106-4117.
    • (1998) Blood , vol.91 , pp. 4106-4117
    • Kim, M.1    Cooper, D.D.2    Hayes, S.F.3    Spangrude, G.J.4
  • 20
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck R. M., Bossy-Wetzel E., Green D. R., and Newmeyer D. D. (1997) The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275, 1132-1136.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 23
    • 0030986669 scopus 로고    scopus 로고
    • Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis
    • Kruman I., Bruce-Keller A. J., Bredesen D. E., Waeg G., and Mattson M. P. (1997) Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis. J. Neurosci. 17, 5089-5100.
    • (1997) J. Neurosci. , vol.17 , pp. 5089-5100
    • Kruman, I.1    Bruce-Keller, A.J.2    Bredesen, D.E.3    Waeg, G.4    Mattson, M.P.5
  • 24
    • 0032006868 scopus 로고    scopus 로고
    • Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC 12 cells
    • Kruman I., Guo Q., and Mattson M. P. (1998) Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC 12 cells. J. Neurosci. Res. 51, 293-308.
    • (1998) J. Neurosci. Res. , vol.51 , pp. 293-308
    • Kruman, I.1    Guo, Q.2    Mattson, M.P.3
  • 25
    • 0027221998 scopus 로고
    • NMDA-dependent superoxide production and neurotoxicity
    • Lafon-Cazal M., Pietri S., Culcasi M., and Bockaert J. (1993) NMDA-dependent superoxide production and neurotoxicity. Nature 364, 535-537.
    • (1993) Nature , vol.364 , pp. 535-537
    • Lafon-Cazal, M.1    Pietri, S.2    Culcasi, M.3    Bockaert, J.4
  • 26
    • 0027501851 scopus 로고
    • Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats
    • Linnik M. D., Zobrist R. H., and Hatfield M. D. (1993) Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats. Stroke 24, 2002-2008.
    • (1993) Stroke , vol.24 , pp. 2002-2008
    • Linnik, M.D.1    Zobrist, R.H.2    Hatfield, M.D.3
  • 28
    • 0030897988 scopus 로고    scopus 로고
    • Substrate and inhibitor specificity of interleukin-1 β-converting enzyme and related caspases
    • Margolin N., Raybuck S. A., Wilson K. P., Chen W., Fox T., Gu Y., and Livingston D. J. (1997) Substrate and inhibitor specificity of interleukin-1 β-converting enzyme and related caspases. J. Biol. Chem. 272, 7223-7228.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7223-7228
    • Margolin, N.1    Raybuck, S.A.2    Wilson, K.P.3    Chen, W.4    Fox, T.5    Gu, Y.6    Livingston, D.J.7
  • 29
    • 0031020476 scopus 로고    scopus 로고
    • A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid β-peptide
    • Mark R. J., Lovell M. A., Markesbery W. R., Uchida K., and Mattson M. P. (1997) A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid β-peptide. J. Neurochem. 68, 255-264.
    • (1997) J. Neurochem. , vol.68 , pp. 255-264
    • Mark, R.J.1    Lovell, M.A.2    Markesbery, W.R.3    Uchida, K.4    Mattson, M.P.5
  • 30
    • 0028650421 scopus 로고
    • Calcium and neuronal injury in Alzheimer's disease: Contributions of β-amyloid precursor protein mismetabolism, free radicals, and metabolic compromise
    • Mattson M. P. (1994) Calcium and neuronal injury in Alzheimer's disease: contributions of β-amyloid precursor protein mismetabolism, free radicals, and metabolic compromise. Ann. NY Acad. Sci. 747, 50-76.
    • (1994) Ann. NY Acad. Sci. , vol.747 , pp. 50-76
    • Mattson, M.P.1
  • 31
    • 0025938452 scopus 로고
    • Developmental expression, compartmentalization, and possible role in excitotoxicity of a putative NMDA receptor protein in cultured hippocampal neurons
    • Mattson M. P., Wang H., and Michaelis E. K. (1991) Developmental expression, compartmentalization, and possible role in excitotoxicity of a putative NMDA receptor protein in cultured hippocampal neurons. Brain Res. 565, 94-108.
    • (1991) Brain Res. , vol.565 , pp. 94-108
    • Mattson, M.P.1    Wang, H.2    Michaelis, E.K.3
  • 32
    • 0027319561 scopus 로고
    • Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose
    • Mattson M. P., Zhang Y., and Bose S. (1993a) Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose. Exp. Neurol. 121, 1-13.
    • (1993) Exp. Neurol. , vol.121 , pp. 1-13
    • Mattson, M.P.1    Zhang, Y.2    Bose, S.3
  • 33
    • 0027367765 scopus 로고
    • β-Amyloid precursor protein metabolites and loss of neuronal calcium homeostasis in Alzheimer's disease
    • Mattson M. P., Barger S. W., Cheng B., Lieberburg I., Smith-Swintosky V. L., and Rydel R. E. (1993b) β-Amyloid precursor protein metabolites and loss of neuronal calcium homeostasis in Alzheimer's disease. Trends Neurosci. 16, 409-415.
    • (1993) Trends Neurosci. , vol.16 , pp. 409-415
    • Mattson, M.P.1    Barger, S.W.2    Cheng, B.3    Lieberburg, I.4    Smith-Swintosky, V.L.5    Rydel, R.E.6
  • 34
    • 0029150526 scopus 로고
    • 2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons
    • 2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons. J. Neurochem. 65, 1740-1751.
    • (1995) J. Neurochem. , vol.65 , pp. 1740-1751
    • Mattson, M.P.1    Lovell, M.A.2    Furukawa, K.3    Markesbery, W.R.4
  • 35
    • 0030611750 scopus 로고    scopus 로고
    • Activation of NF-κB protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of Mn-SOD and suppression of peroxynitrite production and protein tyrosine nitration
    • Mattson M. P., Goodman Y., Luo H., Fu W., and Furukawa K. (1997) Activation of NF-κB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of Mn-SOD and suppression of peroxynitrite production and protein tyrosine nitration. J. Neurosci. Res. 49, 681-697.
    • (1997) J. Neurosci. Res. , vol.49 , pp. 681-697
    • Mattson, M.P.1    Goodman, Y.2    Luo, H.3    Fu, W.4    Furukawa, K.5
  • 37
    • 0032487648 scopus 로고    scopus 로고
    • Amyloid β-peptide induces apoptosis-related events in synapses and dendrites
    • Mattson M. P., Partin J., and Begley J. G. (1998b) Amyloid β-peptide induces apoptosis-related events in synapses and dendrites. Brain Res. 807, 167-176.
    • (1998) Brain Res. , vol.807 , pp. 167-176
    • Mattson, M.P.1    Partin, J.2    Begley, J.G.3
  • 38
    • 0031080248 scopus 로고    scopus 로고
    • The role of the caspase family of cysteine proteases in apoptosis
    • Miller D. K. (1997) The role of the caspase family of cysteine proteases in apoptosis. Semin. Immunol. 9, 35-49.
    • (1997) Semin. Immunol. , vol.9 , pp. 35-49
    • Miller, D.K.1
  • 39
    • 0027227533 scopus 로고
    • Synaptic vesicle proteins and early endosomes in cultured hippocampal neurons: Differential effects of brefeldin A in axon and dendrites
    • Mundigl O., Matteoli M., Daniell L., Thomas-Reetz A., Metcalf A., Jahn R., and De Camilli P. (1993) Synaptic vesicle proteins and early endosomes in cultured hippocampal neurons: differential effects of brefeldin A in axon and dendrites. J. Cell Biol. 122, 1207-1221.
    • (1993) J. Cell Biol. , vol.122 , pp. 1207-1221
    • Mundigl, O.1    Matteoli, M.2    Daniell, L.3    Thomas-Reetz, A.4    Metcalf, A.5    Jahn, R.6    De Camilli, P.7
  • 40
    • 0030836301 scopus 로고    scopus 로고
    • Atypical protein kinase C iota protects human leukemia cells against drug-induced apoptosis
    • Murray N. R. and Fields A. P. (1997) Atypical protein kinase C iota protects human leukemia cells against drug-induced apoptosis. J. Biol. Chem. 272, 27521-27524.
    • (1997) J. Biol. Chem. , vol.272 , pp. 27521-27524
    • Murray, N.R.1    Fields, A.P.2
  • 41
    • 0028448460 scopus 로고
    • The use of tetrazolium salts to determine sites of damage to the mitochondrial electron transport chain in intact cells following in vitro photodynamic therapy with photofrinII
    • Musser D. A. and Oseroff A. R. (1994) The use of tetrazolium salts to determine sites of damage to the mitochondrial electron transport chain in intact cells following in vitro photodynamic therapy with photofrinII. Photochem. Photobiol. 59, 621-636.
    • (1994) Photochem. Photobiol. , vol.59 , pp. 621-636
    • Musser, D.A.1    Oseroff, A.R.2
  • 42
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim R. W. (1991) Cell death during development of the nervous system. Annu. Rev. Neurosci. 14, 453-501.
    • (1991) Annu. Rev. Neurosci. , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 44
    • 0029072690 scopus 로고
    • Evidence for apoptosis cell death in huntington disease and excitotoxic animal models
    • Portera-Cailliau C., Hedreen J. C., Price D. L., and Koliatsos V. M. (1995) Evidence for apoptosis cell death in Huntington disease and excitotoxic animal models. J. Neurosci. 15, 3775-3787.
    • (1995) J. Neurosci. , vol.15 , pp. 3775-3787
    • Portera-Cailliau, C.1    Hedreen, J.C.2    Price, D.L.3    Koliatsos, V.M.4
  • 46
    • 0030911597 scopus 로고    scopus 로고
    • Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein
    • Puis A., Schmidt S., Grawe F., and Stabel S. (1997) Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein. Proc. Natl. Acad. Sci. USA 94, 6191-6196.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6191-6196
    • Puis, A.1    Schmidt, S.2    Grawe, F.3    Stabel, S.4
  • 47
    • 0025720490 scopus 로고
    • Evidence that protein constituents of postsynaptic membrane specializations are locally synthesized: Analysis of proteins synthesized within synaptosomes
    • Rao A. and Steward O. (1991) Evidence that protein constituents of postsynaptic membrane specializations are locally synthesized: analysis of proteins synthesized within synaptosomes. J. Neurosci. 11, 2881-2895.
    • (1991) J. Neurosci. , vol.11 , pp. 2881-2895
    • Rao, A.1    Steward, O.2
  • 48
    • 0027325097 scopus 로고
    • Pro-oxidants and mitochondrial calcium: Their relationship to apoptosis and oncogenesis
    • Richter C. (1993) Pro-oxidants and mitochondrial calcium: their relationship to apoptosis and oncogenesis. FEBS Lett. 325, 104-107.
    • (1993) FEBS Lett. , vol.325 , pp. 104-107
    • Richter, C.1
  • 51
    • 0029040824 scopus 로고
    • The intracellular component of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction is specifically inhibited by β-amyloid peptides
    • Shearman M. S., Hawtin S. R., and Taylor V. J. (1995) The intracellular component of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction is specifically inhibited by β-amyloid peptides. J. Neurochem. 65, 218-227.
    • (1995) J. Neurochem. , vol.65 , pp. 218-227
    • Shearman, M.S.1    Hawtin, S.R.2    Taylor, V.J.3
  • 53
    • 0028949725 scopus 로고
    • Targeting of mRNAs to subsynaptic microdomains in dendrites
    • Steward O. (1995) Targeting of mRNAs to subsynaptic microdomains in dendrites. Curr. Opin. Cell Biol. 5, 55-61.
    • (1995) Curr. Opin. Cell Biol. , vol.5 , pp. 55-61
    • Steward, O.1
  • 54
    • 0028577208 scopus 로고
    • Immunocytochemical evidence for apoptosis in Alzheimer's disease
    • Su J. H., Anderson A. J., Cummings B., and Cotman C. W. (1994) Immunocytochemical evidence for apoptosis in Alzheimer's disease. Neuroreport 5, 2529-2533.
    • (1994) Neuroreport , vol.5 , pp. 2529-2533
    • Su, J.H.1    Anderson, A.J.2    Cummings, B.3    Cotman, C.W.4
  • 55
    • 0029850342 scopus 로고    scopus 로고
    • Translational machinery in dendrites of hippocampal neurons in culture
    • Tiedge H. and Brosius J. (1996) Translational machinery in dendrites of hippocampal neurons in culture. J. Neurosci. 16, 7171-7181.
    • (1996) J. Neurosci. , vol.16 , pp. 7171-7181
    • Tiedge, H.1    Brosius, J.2
  • 56
    • 0029563461 scopus 로고
    • Apoptosis in amyotrophic lateral sclerosis is not restricted to motor neurons. Bcl-2 expression is increased in unaffected post-central gyrus
    • Troost D., Aten J., Morsink F., and de Jong J. M. (1995) Apoptosis in amyotrophic lateral sclerosis is not restricted to motor neurons. Bcl-2 expression is increased in unaffected post-central gyrus. Neuropathol. Appl. Neurobiol. 21, 498-504.
    • (1995) Neuropathol. Appl. Neurobiol. , vol.21 , pp. 498-504
    • Troost, D.1    Aten, J.2    Morsink, F.3    De Jong, J.M.4
  • 57
    • 0028046038 scopus 로고
    • Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40
    • Vayssiere J. L., Petit P. X., Risler Y., and Mignotte B. (1994) Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40. Proc. Natl. Acad Sci. USA 91, 11752-11756.
    • (1994) Proc. Natl. Acad Sci. USA , vol.91 , pp. 11752-11756
    • Vayssiere, J.L.1    Petit, P.X.2    Risler, Y.3    Mignotte, B.4
  • 58
    • 0028137817 scopus 로고
    • Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons
    • Werth J. L. and Thayer S. A. (1994) Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons. J. Neurosci. 14, 348-356.
    • (1994) J. Neurosci. , vol.14 , pp. 348-356
    • Werth, J.L.1    Thayer, S.A.2
  • 59
  • 60
  • 61
    • 0030987071 scopus 로고    scopus 로고
    • Transducing signals of life and death
    • Yuan J. (1997) Transducing signals of life and death. Curr. Opin. Cell Biol. 9, 247-251.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 247-251
    • Yuan, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.