-
1
-
-
0001387044
-
Orthomyxoviruses
-
Murphy BR. Webster RG: Orthomyxoviruses. In: Virology, Fields BN, Knipe DM, Howley PM (Eds), Raven Press, New York(1996):1397-1445.
-
(1996)
In Virology, Fields BN, Knipe DM, Howley PM (Eds), Raven Press, New York
, pp. 1397-1445
-
-
Murphy, B.R.1
Webster, R.G.2
-
3
-
-
14444284599
-
Characterization of an avian influenza a (H5N1) virus isolated from a child with a fatal respiratory illness
-
Subbarao K, Klimov A, Katz J, Regnery H, Um W, Hall H, Perdue M, Swayne D, Bender C, Huang J, Hemphill M, Rowe T, Shaw M. Xu X, Fukuda K, Cox N: Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness. Science (1998) 279:393-396.
-
(1998)
Science
, vol.279
, pp. 393-396
-
-
Subbarao, K.1
Klimov, A.2
Katz, J.3
Regnery, H.4
Um, W.5
Hall, H.6
Perdue, M.7
Swayne, D.8
Bender, C.9
Huang, J.10
Hemphill, M.11
Rowe, T.12
Shaw, M.13
Xu, X.14
Fukuda, K.15
Cox, N.16
-
4
-
-
0031903499
-
Comparisons of highly virulent H5N1 influenza a viruses isolated from humans and chickens from Hong Kong
-
Suarez DL, Perdue ML, Cox M, Rowe T, Bender C, Huang J, Swayne DE: Comparisons of highly virulent H5N1 influenza A viruses isolated from humans and chickens from Hong Kong. J V7ro/(1998) 72:6678-6688.
-
(1998)
J V7ro/
, vol.72
, pp. 6678-6688
-
-
Suarez, D.L.1
Perdue, M.L.2
Cox, M.3
Rowe, T.4
Bender, C.5
Huang, J.6
De Swayne7
-
5
-
-
0031866130
-
Influenza: An emerging disease
-
Webster RG: Influenza: an emerging disease. Emerg Infect Dis (1998) 4:436-441.
-
(1998)
Emerg Infect Dis
, vol.4
, pp. 436-441
-
-
Webster, R.G.1
-
6
-
-
0003084227
-
Antiviral agents
-
Hirsch MS, Kaplan JC, D'Aquila RT: Antiviral agents. In: Virology, Relds BN, Knipe DM, Howtey PM (Eds), Raven Press, New York (1996):431-466.
-
(1996)
In Virology, Relds BN, Knipe DM, Howtey PM (Eds), Raven Press, New York
, pp. 431-466
-
-
Hirsch, M.S.1
Kaplan, J.C.2
D'Aquila, R.T.3
-
7
-
-
0026603612
-
Emergence and transmission of influenza a viruses resistant to amantadine and rimantadine
-
Hayden FG, Hay AJ: Emergence and transmission of influenza A viruses resistant to amantadine and rimantadine. Curr Top Microbiol Immunol (1992) 176:119-130.
-
(1992)
Curr Top Microbiol Immunol
, vol.176
, pp. 119-130
-
-
Hayden, F.G.1
Hay, A.J.2
-
8
-
-
0030800956
-
Improvement of inactivated influenza virus vaccines
-
Couch RC, Keitel WA, Cate TR: Improvement of inactivated influenza virus vaccines. J Infect Dis (1997) 176(Suppl 1):S38-S44.
-
(1997)
J Infect Dis
, vol.176
, Issue.SUPPL. 1
-
-
Couch, R.C.1
Keitel, W.A.2
Cate, T.R.3
-
9
-
-
9844220300
-
Osterhaus AD, Treanor JJ, Fleming DM, Aoki FY, Nicholson KG, Bohnen AM, Hirst HM, Keene O, Wightman K: Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenza virus infections
-
Hayden FG. Osterhaus AD, Treanor JJ, Fleming DM, Aoki FY, Nicholson KG, Bohnen AM, Hirst HM, Keene O, Wightman K: Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenza virus infections. New Engt J Med (1997) 337:874-880.
-
(1997)
New Engt J Med
, vol.337
, pp. 874-880
-
-
Hayden, F.G.1
-
10
-
-
33749751443
-
-
The first clinical study conducted in multiple centers demonstrating the clinical efficacy and safety of a neuraminidase inhibitor (zanamivir) for the treatment of influenza.
-
-
-
Efficacy, T.F.1
Influenza, S.O.2
-
11
-
-
0031767836
-
New approaches to influenza chemotherapy
-
Calfee DP, Hayden FG: New approaches to influenza chemotherapy. Neuraminidase inhibitors. Drugs (1998) 56:537-553.
-
(1998)
Neuraminidase Inhibitors. Drugs
, vol.56
, pp. 537-553
-
-
Hayden Fg, C.D.P.1
-
12
-
-
0031786423
-
Targeting influenza virus neuraminidase - A new strategy for antiviral therapy
-
Oxford JS, Lambkin R: Targeting influenza virus neuraminidase - a new strategy for antiviral therapy. Drug Disc Today (1998) 3:448-456.
-
(1998)
Drug Disc Today
, vol.3
, pp. 448-456
-
-
Lambkin R, O.J.S.1
-
13
-
-
0030803540
-
Antivirals for pandemic influenza
-
Hayden FG: Antivirals for pandemic influenza. J Infect Diseases (1997) 176(Suppl 1):S56-S61.
-
(1997)
J Infect Diseases
, vol.176
, Issue.SUPPL. 1
-
-
Hayden, F.G.1
-
14
-
-
0027253445
-
A spring-loaded mechanism for the conformations! change of influenza hemagglutinin
-
Carr CM, Kim PS: A spring-loaded mechanism for the conformations! change of influenza hemagglutinin. Cell (1993)73:823-832.
-
(1993)
Cell
, vol.73
, pp. 823-832
-
-
Kim Ps, C.C.M.1
-
15
-
-
0028023726
-
Structure of influenza haemagglutinin at the pH of membrane fusion
-
Bullough PA, Hughson FM, Skehel JJ, Wiley DC: Structure of influenza haemagglutinin at the pH of membrane fusion. Nature (1994) 371:37-43.
-
(1994)
Nature
, vol.371
, pp. 37-43
-
-
Bullough, P.A.1
Hughson, F.M.2
Skehel, J.J.3
Wiley, D.C.4
-
16
-
-
0027523625
-
Inhibition of the fusion-inducing conformational change of influenza hemagglutinin by benzoquinones and hydroquinones
-
Bodian DL, Yamasaki RB, Buswell RL, Steams JF, White JM, Kuntz ID: Inhibition of the fusion-inducing conformational change of influenza hemagglutinin by benzoquinones and hydroquinones. Biochemistry (I993) 32:2967-2978.
-
(1982)
Biochemistry (I993) 32
, pp. 2978
-
-
Bodian, D.L.1
Yamasaki, R.B.2
Buswell, R.L.3
Steams, J.F.4
White, J.M.5
Kuntz, I.D.6
-
17
-
-
0030560967
-
Characterization of a hemagglutinin-specific inhibitor of influenza a virus
-
Luo GX, Colonno R, Krystal M: Characterization of a hemagglutinin-specific inhibitor of influenza A virus. Virology (1996) 226:66-76.
-
(1996)
Virology
, vol.226
, pp. 66-76
-
-
Luo, G.X.1
Colonno, R.2
Krystal, M.3
-
18
-
-
0030894782
-
Luo GX
-
I 17. Luo GX. Torri A, Harte WE, Danetz S, Cianci C, Tiley L. Day S, Mullaney D, Yu KL, Quellet C, Dextraze P, Meanwell N, Colonno R, Krystal M: Molecular mechanism underlying the action of a novel fusion inhibitor of influenza A virus. J Virol (1997) 71:4062-4070.
-
(1997)
Torri A, Harte WE, Danetz S, Cianci C, Tiley L. Day S, Mullaney D, Yu KL, Quellet C, Dextraze P, Meanwell N, Colonno R, Krystal M Molecular Mechanism Underlying the Action of a Novel Fusion Inhibitor of Influenza a Virus. J Virol
, vol.71
, pp. 4062-4070
-
-
-
19
-
-
0030753409
-
Structure-based identification of an induccr of the low-pH conformational change in the influenza virus hemagglutininirreversible inhibition of infectivity
-
Hoffman LR, Kuntz IS, White JM: Structure-based identification of an induccr of the low-pH conformational change in the influenza virus hemagglutinin:irreversible inhibition of infectivity. J V7ro/(1997) 71:8808-8820.
-
(1997)
J V7ro/
, vol.71
, pp. 8808-8820
-
-
Hoffman, L.R.1
Kuntz, I.S.2
White, J.M.3
-
20
-
-
0032169618
-
Inhibition of influenza virus hemagglutinin-mediated membrane fusion by a compound related to podocarpic acid
-
Staschke KA, Hatch SD, Tang JC, Homback WJ, Munroe JE, Colacino JM, Muesing MA: Inhibition of influenza virus hemagglutinin-mediated membrane fusion by a compound related to podocarpic acid. Virology (1998) 248:264-274.
-
(1998)
Virology
, vol.248
, pp. 264-274
-
-
Staschke, K.A.1
Hatch, S.D.2
Tang, J.C.3
Homback, W.J.4
Munroe, J.E.5
Colacino, J.M.6
Muesing, M.A.7
-
21
-
-
17344371121
-
Inhibition of influenza a virus replication by compounds interfering with the fusogenic function of the viral hemagglutinin
-
O'Hara B, Morin J, Palant O, LaRoque J, Bloom JD, Lang Jr SA, CiGrandi MJ, Bradley M, Nilakantan R, Gluzman Y
-
Plotch SJ, O'Hara B, Morin J, Palant O, LaRoque J, Bloom JD, Lang Jr SA, CiGrandi MJ, Bradley M, Nilakantan R, Gluzman Y: Inhibition of influenza A virus replication by compounds interfering with the fusogenic function of the viral hemagglutinin. J V/ro/(1999) 73:140-151.
-
(1999)
J V/ro/
, vol.73
, pp. 140-151
-
-
Plotch, S.J.1
-
22
-
-
0029117350
-
Growth impairment resulting from expression of influenza virus M2 protein in Saccharomyces cerevisiae: Identification of a novel inhibitor of influenza virus
-
Kurtz S, Luo GX, Hahnenberger KM, Brooks C, Gecha O, Ingalls K, Numata Kl, Krystal M: Growth impairment resulting from expression of influenza virus M2 protein in Saccharomyces cerevisiae: Identification of a novel inhibitor of influenza virus. Antimicrob Agents Chemother (1995)39:2204-2209.
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 2204-2209
-
-
Kurtz, S.1
Luo, G.X.2
Hahnenberger, K.M.3
Brooks, C.4
Gecha, O.5
Ingalls, K.6
Kl, N.7
Krystal, M.8
-
23
-
-
0029665753
-
Characterization of inhibition of M2 ion channel activity by BL-1743, an inhibitor of influenza a virus
-
Tu Q, Pinto LH, Luo GX, Shaughnessy MA, Mullaney D, Kurtz S, Krystal M, Lamb RA: Characterization of inhibition of M2 ion channel activity by BL-1743, an inhibitor of influenza A virus. J V/ro/(1996) 70:4246-4252.
-
(1996)
J V/ro/
, vol.70
, pp. 4246-4252
-
-
Tu, Q.1
Pinto, L.H.2
Luo, G.X.3
Shaughnessy, M.A.4
Mullaney, D.5
Kurtz, S.6
Krystal, M.7
Lamb, R.A.8
-
24
-
-
0032005664
-
How to overcome resistance of influenza a viruses against adamantane derivatives
-
Scholtissek C, Quack G, Klenk HD, Webster RG: How to overcome resistance of influenza A viruses against adamantane derivatives. Antiviral Res (1998) 37:83-95.
-
(1998)
Antiviral Res
, vol.37
, pp. 83-95
-
-
Scholtissek, C.1
Quack, G.2
Klenk, H.D.3
Webster, R.G.4
-
25
-
-
0030934244
-
Different modes of inhibition by adamantane amine derivatives and natural polyamines of the functionally/reconstituted Influenza virus M2 proton channel protein
-
Heider H, Schroeder C
-
Lin Tl, Heider H, Schroeder C: Different modes of inhibition by adamantane amine derivatives and natural polyamines of the functionally/reconstituted Influenza virus M2 proton channel protein. J Gen Virol (1997) 78:767-774.
-
(1997)
J Gen Virol
, vol.78
, pp. 767-774
-
-
Lin, T.1
-
26
-
-
0028171260
-
Inhibition of cap (m?GpppXm)-dependent endonuclease of influenza virus by 4-substituted 2,4-dioxobutanoic acid compounds
-
Tomassini J, Seinick H, Davies ME, Armstrong ME, Baldwin J, Bourgeois M, Hastings J, Hazuda D, Lewis J, Mcclements W, Ponticello G, Radzilowski E, Smith G, Tebben A, Wolfe A: Inhibition of cap (m?GpppXm)-dependent endonuclease of influenza virus by 4-substituted 2,4-dioxobutanoic acid compounds. Antimicrob Agents Chemother (1994) 38:28272837.
-
(1994)
Antimicrob Agents Chemother
, vol.38
, pp. 28272837
-
-
Tomassini, J.1
Seinick, H.2
Davies, M.E.3
Armstrong, M.E.4
Baldwin, J.5
Bourgeois, M.6
Hastings, J.7
Hazuda, D.8
Lewis, J.9
Mcclements, W.10
Ponticello, G.11
Radzilowski, E.12
Smith, G.13
Tebben, A.14
Wolfe, A.15
-
27
-
-
0029800910
-
Identification of N-hydroxamic acid and N-hydroxyimide compounds that inhibit the influenza virus polymerase
-
Chung TOY, Meanwell N, Putz H, Hagen M, Colonno RJ, Krystal M
-
Cianci C, Chung TOY, Meanwell N, Putz H, Hagen M, Colonno RJ, Krystal M: Identification of N-hydroxamic acid and N-hydroxyimide compounds that inhibit the influenza virus polymerase. Antiviral Chem Chemother (1996) 7:335360.
-
(1996)
Antiviral Chem Chemother
, vol.7
, pp. 335360
-
-
Cianci, C.1
-
28
-
-
0020696905
-
The gene structure and replication of influenza virus
-
. 27. Lamb RA, Choppin PW: The gene structure and replication of influenza virus. Annu Rev Biochem (1983) 52:467-506.
-
(1983)
Annu Rev Biochem
, vol.52
, pp. 467-506
-
-
Lamb, R.A.1
Choppin, P.W.2
-
29
-
-
0020629047
-
Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 a resolution
-
Varghese JN, Laver WG, Cdman PM: Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 A resolution. Nature (1983) 303:35-40.
-
(1983)
Nature
, vol.303
, pp. 35-40
-
-
Varghese, J.N.1
Laver, W.G.2
Cdman, P.M.3
-
30
-
-
0020633096
-
Structure of the catalytic and antigenic sites in influenza virus neuraminidase
-
Colman PM, Varghese JN, Laver WG: Structure of the catalytic and antigenic sites in influenza virus neuraminidase. Nature (1983) 303:41-44.
-
(1983)
Nature
, vol.303
, pp. 41-44
-
-
Colman, P.M.1
Varghese, J.N.2
Laver, W.G.3
-
31
-
-
0026665418
-
The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor
-
McKimm-Breschkin JL, Caldewell JB, Kortl AA, Colman PM
-
Varghese JN, McKimm-Breschkin JL, Caldewell JB, Kortl AA, Colman PM: The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor. Proteins (1992) 14:327-332.
-
(1992)
Proteins
, vol.14
, pp. 327-332
-
-
Varghese, J.N.1
-
32
-
-
0016272701
-
Characterization of temperature-sensitive Influenza virus mutants defective in neuraminidase
-
Palese P, Tobita K, Ueda M, Compans RW: Characterization of temperature-sensitive Influenza virus mutants defective in neuraminidase. Virology (1974) 61:397-410.
-
(1974)
Virology
, vol.61
, pp. 397-410
-
-
Palese, P.1
Tobita, K.2
Ueda, M.3
Compans, R.W.4
-
33
-
-
0031550787
-
Hemagglutinin specificity and neuraminidase coding capacity of neuraminidasedeficient influenza viruses
-
Yang P, Bansal A, Liu CG, Air GM: Hemagglutinin specificity and neuraminidase coding capacity of neuraminidasedeficient influenza viruses. Virology (1997) 229:155-165.
-
(1997)
Virology
, vol.229
, pp. 155-165
-
-
Yang, P.1
Bansal, A.2
Liu, C.G.3
Air, G.M.4
-
34
-
-
0023803844
-
The molecular biology of influenza virus pathogeniclty
-
Klenk HD, Rott R: The molecular biology of influenza virus pathogeniclty. Adv Virus Res (1988) 34:247-281.
-
(1988)
Adv Virus Res
, vol.34
, pp. 247-281
-
-
Klenk, H.D.1
Rott, R.2
-
35
-
-
0015959249
-
Inhibition of neuraminidase activity by derivatives of 2-deoxy-2,3dehydro-N-acetylneuraminic acid
-
Meindl P, Bodo G, Palese P, Schulman J, Tuppy H: Inhibition of neuraminidase activity by derivatives of 2-deoxy-2,3dehydro-N-acetylneuraminic acid. Virology (1974) 58:457463.
-
(1974)
Virology
, vol.58
, pp. 457463
-
-
Meindl, P.1
Bodo, G.2
Palese, P.3
Schulman, J.4
Tuppy, H.5
-
36
-
-
0016244226
-
Inhibition of influenza and parainfluenza virus replication in tissue culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA)
-
Palese P, Schulman JL, Bodo G, Meindl P: Inhibition of influenza and parainfluenza virus replication in tissue culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA). Virology (1974) 59:490-498.
-
(1974)
Virology
, vol.59
, pp. 490-498
-
-
Palese, P.1
Schulman, J.L.2
Bodo, G.3
Meindl, P.4
-
37
-
-
0026508847
-
The 2.2 A resolution crystal structure of influenza B neuraminidase and its complex with sialic acid
-
Burmeisler WP, Ruigrok RWH, Cusack S: The 2.2 A resolution crystal structure of influenza B neuraminidase and its complex with sialic acid. EMBO J(1992) 11:49-56.
-
(1992)
EMBO J
, vol.11
, pp. 49-56
-
-
Burmeisler, W.P.1
Ruigrok, R.W.H.2
Cusack, S.3
-
38
-
-
0027287506
-
Rational design of potent sialidase-based inhibitors of influenza virus replication
-
Kok GB, Pegg MS, Dyason JC, Jin B, Van Phan T, Smythe ML, White HF, Woods JM. Bethell RC, Hotham VJ, Cameron JM, Penn CR
-
Von Itzstein M, Wu WY. Kok GB, Pegg MS, Dyason JC, Jin B, Van Phan T, Smythe ML, White HF, Woods JM. Bethell RC, Hotham VJ, Cameron JM, Penn CR: Rational design of potent sialidase-based inhibitors of influenza virus replication. Nature (1993) 363:418-423.
-
(1993)
Nature
, vol.363
, pp. 418-423
-
-
Von Itzstein, M.1
Wu, W.Y.2
-
39
-
-
0031048319
-
-
Lew W, Williams MA, LJU HT, Zhang LJ, Swaminathan S, Bischofberger N. Chen MS, Mendel DB, Tai CY, Laver WG, Stevens RC: Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis and structural analysis of cabocyclic sialic acid analogues with potent anti-influenza activity.
-
Kirn CD, Lew W, Williams MA, LJU HT, Zhang LJ, Swaminathan S, Bischofberger N. Chen MS, Mendel DB, Tai CY, Laver WG, Stevens RC: Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis and structural analysis of cabocyclic sialic acid analogues with potent anti-influenza activity. JAm Chem Soc (1997) 119:681-690.
-
(1997)
JAm Chem Soc
, vol.119
, pp. 681-690
-
-
Kirn, C.D.1
-
40
-
-
15444353753
-
Escarpe PA, Mendel DB, Laver WG, Stevens RC: Structureactivity relationship studies of novel carbocyclic influenza neuraminidase inhibitors
-
Kirn CU, Lew W, Williams MA, Wu H, Zhang L, Chen X. Escarpe PA, Mendel DB, Laver WG, Stevens RC: Structureactivity relationship studies of novel carbocyclic influenza neuraminidase inhibitors. J Med Chem (1998) 41:2451 -2460.
-
(1998)
J Med Chem
, vol.41
, pp. 2451-2460
-
-
Kirn, C.U.1
Lew, W.2
Williams, M.A.3
Wu H4
Zhang, L.5
Chen, X.6
-
41
-
-
0027162942
-
4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of sialidase (neuraminidase) and of growth of a wide range of influenza a and B viruses in vitro
-
Woods JM, Bethell RC, Coates JAV, Healy N, Hiscox SA, Pearson BA, Ryan DM, Ticehurst J, Tilling J, Walcott SM, Penn CR: 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitro. Antimicrob Agents Chemother (1993)37:1473-1479.
-
(1993)
Antimicrob Agents Chemother
, vol.37
, pp. 1473-1479
-
-
Woods, J.M.1
Bethell, R.C.2
Coates, J.A.V.3
Healy, N.4
Hiscox, S.A.5
Pearson, B.A.6
Ryan, D.M.7
Ticehurst, J.8
Tilling, J.9
Walcott, S.M.10
Penn, C.R.11
-
42
-
-
0028029338
-
Anti-influenza virus activity of the nnuraminidase inhibitor 4-guanidinoneu5Ac2en in cell culture and in human respiratory epithelium
-
Hayden FG, Rollins BS, Madren LK: Anti-influenza virus activity of the nnuraminidase inhibitor 4-guanidinoneu5Ac2en in cell culture and in human respiratory epithelium. Antiviral Res (1994) 25:123-131 (erratum appears in Antiviral Res (1994) 25:287.
-
(1994)
Antiviral Res
, vol.25
, pp. 287
-
-
Hayden, F.G.1
Rollins, B.S.2
Madren, L.K.3
-
43
-
-
0027981472
-
Inhibition of influenza virus replication in mice by GG-167 (4-guanidino2,4-dideoxy-2,3-dehydro-N-acetylneuraminlc acid) is consistent with extracellular activity of viral neuraminidase (sialidase)
-
Ryan DM, Tlcehuret J, Dempsey MH, Penn CR: Inhibition of influenza virus replication in mice by GG-167 (4-guanidino2,4-dideoxy-2,3-dehydro-N-acetylneuraminlc acid) is consistent with extracellular activity of viral neuraminidase (sialidase). Antimicrob Agents Chemother (1994) 38:2270-2275.Q
-
(1994)
Antimicrob Agents Chemother
, vol.38
, pp. 2270-2275
-
-
Ryan, D.M.1
Tlcehuret, J.2
Dempsey, M.H.3
Penn, C.R.4
-
44
-
-
0027967179
-
Inhibition of the growth of Influenza viruses in vitro by 4-guanidino-2,4dideoxy-2,3-dehydro-N-acetylneuraminic acid
-
Thomas GP, Forsyth W, Penn CR, McCauley JW: Inhibition of the growth of Influenza viruses in vitro by 4-guanidino-2,4dideoxy-2,3-dehydro-N-acetylneuraminic acid. Antiviral Res (1994)24:351-356.
-
(1994)
Antiviral Res
, vol.24
, pp. 351-356
-
-
Thomas, G.P.1
Forsyth, W.2
Penn, C.R.3
McCauley, J.W.4
-
45
-
-
0028827789
-
GG-167 (4-guanidino-2,4dideoxy-2,3-dehydro-N-acetylneuraminic acid) is a potent inhibitor of influenza virus in ferrets
-
Ryan DM, Ticehurst J, Dempsey MH: GG-167 (4-guanidino-2,4dideoxy-2,3-dehydro-N-acetylneuraminic acid) is a potent inhibitor of influenza virus in ferrets. Antimicrob Agents Chemother (1995) 39:2583-2584.
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 2583-2584
-
-
Ryan, D.M.1
Ticehurst, J.2
Dempsey, M.H.3
-
46
-
-
0030032258
-
Safety and efficacy of the neuraminidase inhibitor GG-167 in experimental human influenza
-
Hayden FG, Treanor JJ, Betts RF, Lobo M, Esinhart JD, Hussey EK: Safety and efficacy of the neuraminidase inhibitor GG-167 in experimental human influenza. JAMA (1996) 275:295-299.
-
(1996)
JAMA
, vol.275
, pp. 295-299
-
-
Hayden, F.G.1
Treanor, J.J.2
Betts, R.F.3
Lobo, M.4
Esinhart, J.D.5
Hussey, E.K.6
-
47
-
-
0030724941
-
Effects of the neuraminidase inhibitor zanamivir on otologic manifestations of experimental human influenza
-
Walker JB, Hussey EK, Treanor JJ, Montalvo Jr A, Hayden FG: Effects of the neuraminidase inhibitor zanamivir on otologic manifestations of experimental human influenza J Infect Dis (1998)176:1417-1422.
-
(1998)
J Infect Dis
, vol.176
, pp. 1417-1422
-
-
Walker, J.B.1
Hussey, E.K.2
Treanor, J.J.3
Montalvo Jr., A.4
Hayden, F.G.5
-
48
-
-
0031925539
-
Effect of rimantadine treatment on clinical manifestations and otologic complication in adults experimentally infected with influenza a (H1N1) virus
-
Skoner DP, Alper CM, Alien G, Moody SA, Seroky JT, Hayden FG
-
Doyle WJ, Skoner DP, Alper CM, Alien G, Moody SA, Seroky JT, Hayden FG: Effect of rimantadine treatment on clinical manifestations and otologic complication in adults experimentally infected with influenza A (H1N1) virus. J Infect Dis (1998) 177:1260-1265.
-
(1998)
J Infect Dis
, vol.177
, pp. 1260-1265
-
-
Doyle, W.J.1
-
49
-
-
33747609048
-
Chemoprophylaxis of influenza a infections in mice and ferrets with neuraminidase inhibitors exemplified by zanamivir (GG-167)
-
Fenton RJ, Owens IJ, Mortey PJ: Chemoprophylaxis of influenza A infections in mice and ferrets with neuraminidase inhibitors exemplified by zanamivir (GG-167). Antiviral Res (1998)37:A72.
-
(1998)
Antiviral Res
, vol.37
-
-
Fenton, R.J.1
Owens, I.J.2
Mortey, P.J.3
-
50
-
-
33749809964
-
-
Monto AS, Robinson DP, Herlocher L, Hinson JM, Elliott M, Keene O: Efficacy and safety of zanamivir in prevention of influenza among healthy adults. /CMC (1998) 38: LB-7.
-
(1998)
Efficacy and Safety of Zanamivir in Prevention of Influenza among Healthy Adults. /CMC
, vol.38
-
-
Monto, A.S.1
Robinson, D.P.2
Herlocher, L.3
Hinson, J.M.4
Elliott, M.5
Keene, O.6
-
51
-
-
0345350607
-
Protective efficacy of intravenous zanamivir in experimental human influenza
-
Carfee DP, Peng AW, Cass LMR, Lobo M, Hayden FG: Protective efficacy of intravenous zanamivir in experimental human influenza. ICAAC (1998) 38: H-58.
-
(1998)
ICAAC
, vol.38
-
-
Carfee, D.P.1
Peng, A.W.2
Lmr, C.3
Lobo, M.4
Hayden, F.G.5
-
52
-
-
0031919227
-
Oral administration of a prodrug of the influenza virus neuraminidase inhibitor GS-4071 protects mice and ferrets against influenza infection
-
Mendel DB, Tai CY, Escarped PA, U W, Sidwell RW, Huffman JH, Sweet C, Jakeman KJ, Merson J, Lacy SA, Lew W, Williams MA, Zhang L, Chen MS, Bischofberger N, Kim CU: Oral administration of a prodrug of the influenza virus neuraminidase inhibitor GS-4071 protects mice and ferrets against influenza infection. Antimicrob Agents Chemother (1998)42:640-646.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 640-646
-
-
Mendel, D.B.1
Tai, C.Y.2
Escarped, P.A.3
Sidwell, R.W.4
Huffman, J.H.5
Sweet, C.6
Jakeman, K.J.7
Merson, J.8
Lacy, S.A.9
Lew, W.10
Williams, M.A.11
Zhang, L.12
Chen, M.S.13
Bischofberger, N.14
Kim, C.U.15
-
53
-
-
0031916471
-
Identification of GS4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS-4071
-
Li W, Escarpe PA, Eisenberg EJ, Cundy KC, Sweet C, Jakeman KJ, Merson J, Lew W, Williams M, Zhang L, Kim CU, Bischofberger N, Chen MS, Mendel DB: Identification of GS4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS-4071. Antimicrob Agents Chemother (1998)42:647-653.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 647-653
-
-
Li, W.1
Escarpe, P.A.2
Eisenberg, E.J.3
Cundy, K.C.4
Sweet, C.5
Jakeman, K.J.6
Merson, J.7
Lew, W.8
Williams, M.9
Zhang, L.10
Kim, C.U.11
Bischofberger, N.12
Chen, M.S.13
Mendel, D.B.14
-
54
-
-
0030822685
-
-
Eisenberg EJ. Bidgood A, Cundy KC: Penetration of GS-4071, a novel influenza neuraminidase inhibitor, into rat bronchoalveolar lining fluid following oral administration of the prodrug GS-4104. Antimcrob Agents Chemother (1997) 41:1949-1952.
-
(1997)
Antimcrob Agents Chemother
, vol.41
, pp. 1949-1952
-
-
Eisenberg, E.J.1
Bidgood, A.2
Inhibitor, A.N.3
-
55
-
-
0032007378
-
-
Barnard DL, Bailey KW, Wong MH. (1998) 37:107120.
-
Sidwell RW, Huffman JH. Barnard DL, Bailey KW, Wong MH. Morrison A, Syndergaard T. Kirn CU: Inhibition of Influenza virus infections in mice by GS-4104, an orally effective influenza virus neuraminidase inhibitor. Antiviral Res (1998) 37:107120.
-
Morrison A, Syndergaard T. Kirn CU: Inhibition of Influenza Virus Infections in Mice by GS-4104, an Orally Effective Influenza Virus Neuraminidase Inhibitor. Antiviral Res
-
-
Sidwell, R.W.1
Huffman, J.H.2
-
56
-
-
33749716862
-
Hayden FG, Schultz-Cherry S, Miller M, Mills RG: Oral GS-4104 prevents experimental Infection of humans with influenza a (H1N1) virus
-
Treanor JJ, Betts RF, Kallas E, Evans T. Hayden FG, Schultz-Cherry S, Miller M, Mills RG: Oral GS-4104 prevents experimental Infection of humans with influenza A (H1N1) virus. Int Conf Antiviral Res, (1998) 199.
-
(1998)
Int Conf Antiviral Res
, pp. 199
-
-
Treanor, J.J.1
Betts, R.F.2
Kallas, E.3
Evans, T.4
-
57
-
-
0009553341
-
Efficacy of oral GS-4104 in treating acute influenza
-
Vrooman PS, Hayden FG, Kinnersley N, Ward P, Mills RG
-
Treanor JJ, Vrooman PS, Hayden FG, Kinnersley N, Ward P, Mills RG: Efficacy of oral GS-4104 in treating acute influenza. ICAAC (1998) 38: LB-4.
-
(1998)
ICAAC
, vol.38
-
-
Treanor, J.J.1
-
59
-
-
0013580711
-
Safety and efficacy of oral GS4104 in long-term prophylaxis of natural influenza
-
Atmer R, Schilling M, Johnson C, Poretz D, Parr D, Huson L, Ward P, Mills R
-
Hayden FG, Atmer R, Schilling M, Johnson C, Poretz D, Parr D, Huson L, Ward P, Mills R: Safety and efficacy of oral GS4104 in long-term prophylaxis of natural influenza. ICAAC (1998)38:LB-6.
-
(1998)
ICAAC
, vol.38
-
-
Hayden, F.G.1
-
60
-
-
0022477122
-
Measurement of the mutation rates of animal viruses: Influenza virus and poliovirus type 1
-
Moscona A, Pan WT, Leider JM, Palese P
-
Parvin JD, Moscona A, Pan WT, Leider JM, Palese P: Measurement of the mutation rates of animal viruses: influenza virus and poliovirus type 1. J Vim! (1986) 59:377383.
-
(1986)
J Vim!
, vol.59
, pp. 377383
-
-
Parvin, J.D.1
-
61
-
-
0030053758
-
Generation and characterization of variants of NWS/G70C influenza virus after in vitro passage in 4-amino-Neu5Ac2en and 4guanidino-Neu5Ac2en
-
Blick TJ, Sahasrabudhe A, Tiong T, Marshall D, Hart GJ, Bethell RC, Penn CR
-
McKimm-Breschkin JL, Blick TJ, Sahasrabudhe A, Tiong T, Marshall D, Hart GJ, Bethell RC, Penn CR: Generation and characterization of variants of NWS/G70C influenza virus after in vitro passage in 4-amino-Neu5Ac2en and 4guanidino-Neu5Ac2en. Antimicrob Agents Chemother (1996) 40:40-46.
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 40-46
-
-
McKimm-Breschkin, J.L.1
-
62
-
-
0000024891
-
Selection of influenza virus with reduced sensitivity in vitro to the neuraminidase inhibitor GG-167 (4-guanidino-Neu5Ac2en): Changes in the hemaggiutinin may compensate for loss of neuraminidase activity
-
Bamett JM, Bethell RC, Fenton R, Gearing KL, Healy N, Jowett AJ: Brown LE, Hampson AW, Webster RG (Eds), Elsevier Science, Amsterdam
-
Penn CR, Bamett JM, Bethell RC, Fenton R, Gearing KL, Healy N, Jowett AJ: Selection of influenza virus with reduced sensitivity in vitro to the neuraminidase inhibitor GG-167 (4-guanidino-Neu5Ac2en): changes in the hemaggiutinin may compensate for loss of neuraminidase activity. In: Options for the control of influenza III, Brown LE, Hampson AW, Webster RG (Eds), Elsevier Science, Amsterdam (1996):735-740.
-
(1996)
Options for the Control of Influenza III
, pp. 735-740
-
-
Penn, C.R.1
-
63
-
-
0030028671
-
Characterization of mutants of influenza a virus selected with the neuraminidase inhibitor 4-guanidinoNeu5Ac2en
-
Bethell R, Hart GJ, Murti KG, Penn CR, Webster RG
-
Gubareva LV, Bethell R, Hart GJ, Murti KG, Penn CR, Webster RG: Characterization of mutants of influenza A virus selected with the neuraminidase inhibitor 4-guanidinoNeu5Ac2en. J Virol (1996) 70:1818-1827.
-
(1996)
J Virol
, vol.70
, pp. 1818-1827
-
-
Gubareva, L.V.1
-
64
-
-
0031724750
-
Evidence for zanamivir resistance in an immunocompromised child infected with influenza B virus
-
Matrosovich MN, Brenner MK, Bethell RC, Webster RG
-
Gubareva LV, Matrosovich MN, Brenner MK, Bethell RC, Webster RG: Evidence for zanamivir resistance in an immunocompromised child infected with influenza B virus. J Infect Diseases (1998) 178:1257-1262.
-
(1998)
J Infect Diseases
, vol.178
, pp. 1257-1262
-
-
Gubareva, L.V.1
-
65
-
-
0029560199
-
Molecular basis for the resistance of influenza viruses to 4-guanidino-Neu5Ac2en
-
Colacino JM, Baxter AJ, Air GM, Bansal A, Homback WJ, Munroe JE, Laver WG
-
Staschke KA, Colacino JM, Baxter AJ, Air GM, Bansal A, Homback WJ, Munroe JE, Laver WG: Molecular basis for the resistance of influenza viruses to 4-guanidino-Neu5Ac2en. Virology (1995) 214:642-646.
-
(1995)
Virology
, vol.214
, pp. 642-646
-
-
Staschke, K.A.1
-
66
-
-
0031572287
-
A single sequence change destabilizes the influenza virus neuraminidase tetramer
-
Chirgadze NY, Carman E, Murti KG, Loncharich RJ, Baxter AJ, Staschke KA, Laver WG
-
Colacino JM, Chirgadze NY, Carman E, Murti KG, Loncharich RJ, Baxter AJ, Staschke KA, Laver WG: A single sequence change destabilizes the influenza virus neuraminidase tetramer. Virology (1997) 236:66-75.
-
(1997)
Virology
, vol.236
, pp. 66-75
-
-
Colacino, J.M.1
-
67
-
-
0032526697
-
Drug design against a shifting target: A structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase
-
Smith PW, Sollis SL, Blick TJ, Sahasrabudhe A, McKimm-Breschkin JL, Colman PM
-
Varghese JN, Smith PW, Sollis SL, Blick TJ, Sahasrabudhe A, McKimm-Breschkin JL, Colman PM: Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase. Structure (1998) 6:735-746.
-
(1998)
Structure
, vol.6
, pp. 735-746
-
-
Varghese, J.N.1
-
68
-
-
0031000886
-
Catalytic and framework mutations in the neuraminidase active site of influenza viruses that are resistant to 4guanidino-neu5Ac2en
-
Robinson MJ, Bethell RC, Webster RG
-
Gubareva LV, Robinson MJ, Bethell RC, Webster RG: Catalytic and framework mutations in the neuraminidase active site of influenza viruses that are resistant to 4guanidino-neu5Ac2en. J V/ro/(1997) 71:3385-3390.
-
(1997)
J V/ro/
, vol.71
, pp. 3385-3390
-
-
Gubareva, L.V.1
-
69
-
-
0029585928
-
Generation and characterization of an Influenza virus neuraminidase variant with decreased sensitivity to the neuraminidasespeclfic Inhibitor 4-guanidino-neu5Ac2en
-
Tiong T, Sahasrabudhe A, Varghese JN, Colman PM, Hart GJ, Bethell RC, McKimm-Breschkin JL
-
Blick TJ, Tiong T, Sahasrabudhe A, Varghese JN, Colman PM, Hart GJ, Bethell RC, McKimm-Breschkin JL: Generation and characterization of an Influenza virus neuraminidase variant with decreased sensitivity to the neuraminidasespeclfic Inhibitor 4-guanidino-neu5Ac2en. Virology (1995) 214:475-484.
-
(1995)
Virology
, vol.214
, pp. 475-484
-
-
Blick, T.J.1
-
70
-
-
0031734170
-
Substrate and inhibitor interactions with mutant influenza virus neuramindases
-
McKimm-Breschkin JL, Bethell RC: Substrate and inhibitor interactions with mutant influenza virus neuramindases. Int Antiviral News (1998) 6:147-150.
-
(1998)
Int Antiviral News
, vol.6
, pp. 147-150
-
-
McKimm-Breschkin, J.L.1
Bethell, R.C.2
-
71
-
-
0030296267
-
Mutation in the influenza virus neuraminidase gene resulting in decreased sensitivity to the neuraminidase inhibitor 4-guanidino-neu5Ac2en leads to instability of the enzyme
-
McDonald M, Blick TJ, Colman PM
-
McKimm-Breschkin JL, McDonald M, Blick TJ, Colman PM: Mutation in the influenza virus neuraminidase gene resulting in decreased sensitivity to the neuraminidase inhibitor 4-guanidino-neu5Ac2en leads to instability of the enzyme. Virology (1996) 225:240-242.
-
(1996)
Virology
, vol.225
, pp. 240-242
-
-
McKimm-Breschkin, J.L.1
-
72
-
-
0032551595
-
-
Lawrence L, Epa VC, Varghese JN, Colman PM, McKimm-Breschkin JL: Substrate, inhibitor or antibody stabilizes the Glu119 Gly mutant influenza virus neuraminidase.
-
Sahasrabudhe A. Lawrence L, Epa VC, Varghese JN, Colman PM, McKimm-Breschkin JL: Substrate, inhibitor or antibody stabilizes the Glu119 Gly mutant influenza virus neuraminidase. Virology (1998) 247:14-21.
-
(1998)
Virology
, vol.247
, pp. 14-21
-
-
Sahasrabudhe, A.1
-
73
-
-
0031787185
-
Characterization of human influenza virus variants selected in vitro in the presence of the neuraminidase inhibitor GS-4071
-
Escarpe PA, Sidwell RW, Williams MA, Lew W, Wu H, Kim CU, Mendel DB
-
Tai CY, Escarpe PA, Sidwell RW, Williams MA, Lew W, Wu H, Kim CU, Mendel DB: Characterization of human influenza virus variants selected in vitro in the presence of the neuraminidase inhibitor GS-4071. Antimicrob Agents Chemother (1998) 42:3234-3241.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 3234-3241
-
-
Tai, C.Y.1
-
74
-
-
0031911783
-
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors
-
Sahasrabudhe A, Blick TJ, McDonald M, Colman PM, Hart GJ, Bethell RC, Varghese JN
-
McKimm-Breschkin JL, Sahasrabudhe A, Blick TJ, McDonald M, Colman PM, Hart GJ, Bethell RC, Varghese JN: Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors. J V//o/(1998) 72:2456-2462.
-
(1998)
J V//o/
, vol.72
, pp. 2456-2462
-
-
McKimm-Breschkin, J.L.1
-
75
-
-
0031552380
-
Guanidinobenzoic acid inhibitors of influenza virus neuraminidase
-
Jedrzejas MJ, Singh S, Brouillette WJ, Air GM, Laver WG, Babu YS, Bantia S, Chand P, Chu N, Montgomery JA, Walsh DA, Luo M
-
Sudbeck EA, Jedrzejas MJ, Singh S, Brouillette WJ, Air GM, Laver WG, Babu YS, Bantia S, Chand P, Chu N, Montgomery JA, Walsh DA, Luo M: Guanidinobenzoic acid inhibitors of influenza virus neuraminidase. J Mol Biol (1997) 267:584594.
-
(1997)
J Mol Biol
, vol.267
, pp. 584594
-
-
Sudbeck, E.A.1
-
76
-
-
0029099621
-
Structure-based inhibitors of influenza virus sialidase
-
Jedrzejas MJ, Air GM, Luo M, Laver WG, Brouillette WJ
-
Singh S, Jedrzejas MJ, Air GM, Luo M, Laver WG, Brouillette WJ: Structure-based inhibitors of influenza virus sialidase. A benzole acid lead with novel interaction. J Med Chem (1995)38:3217-25.
-
(1995)
A Benzole Acid Lead with Novel Interaction. J Med Chem
, vol.38
, pp. 3217-3225
-
-
Singh, S.1
-
77
-
-
15144343348
-
Design and synthesis of benzole acid derivatives as influenza neuraminidase inhibitors using structure-based drug design
-
Babu YS, Bantia S, Chu N, Cole LB, Kotian PL, Laver WG, Montgomery JA, Pathak VP, Petty SL, Shrout DP, Walsh DA, Walsh GKl
-
Chànd P, Babu YS, Bantia S, Chu N, Cole LB, Kotian PL, Laver WG, Montgomery JA, Pathak VP, Petty SL, Shrout DP, Walsh DA, Walsh GKl: Design and synthesis of benzole acid derivatives as influenza neuraminidase inhibitors using structure-based drug design. J Med Chem (1997) 40:40304052.
-
(1997)
J Med Chem
, vol.40
, pp. 40304052
-
-
Chànd, P.1
-
78
-
-
0031956393
-
Generation and characterization of a mutant of influenza a virus selected with the neuraminidase inhibitor BCX-140
-
Ghate AA, Ananth SL, Babu YS, Air GM, Walsh GM
-
Bantia S, Ghate AA, Ananth SL, Babu YS, Air GM, Walsh GM: Generation and characterization of a mutant of influenza A virus selected with the neuraminidase inhibitor BCX-140. Antimicrob Agents Chemother (1998) 42:801-807.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 801-807
-
-
Bantia, S.1
-
79
-
-
15644379365
-
Dihydropyrancarboxamides related to zanamivir: A new series of inhibitors of influenza virus sialidases. 1. Discovery, synthesis, biological activity and structureactivity relationships of 4-guanidino- And 4-amino-4Hpyran-6-carboxamides
-
Sollid SL, Howes PD, Cherry PC, Starkey ID, Cobley KN, Weston H, Scicinski J, Merritt A, Whittington A, Wyatt P, Taylor N, Green D, Betheil R, Madar S, Fenton RJ, Morley PF, Pateman T, Beresford A
-
Smith PW, Sollid SL, Howes PD, Cherry PC, Starkey ID, Cobley KN, Weston H, Scicinski J, Merritt A, Whittington A, Wyatt P, Taylor N, Green D, Betheil R, Madar S, Fenton RJ, Morley PF, Pateman T, Beresford A: Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 1. Discovery, synthesis, biological activity and structureactivity relationships of 4-guanidino- and 4-amino-4Hpyran-6-carboxamides. J Med Chem (1998) 41 -.787-797.
-
(1998)
J Med Chem
, vol.41
, pp. 787-797
-
-
Smith, P.W.1
-
80
-
-
0032510373
-
Dihydropyrancarboxamides related to zanamivir: A new series of inhibitors of influenza virus sialidases. 2
-
Cleasby A, Singh O, Skarynski T, Wonacott AJ, SMith PW, Sollis SL, Howes PD, Cherry PC, Bethell R, Colman P, Varghese J
-
Taylor NR, Cleasby A, Singh O, Skarynski T, Wonacott AJ, SMith PW, Sollis SL, Howes PD, Cherry PC, Bethell R, Colman P, Varghese J: Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6carboxamides and sialidase from influenza virus types A and B. J Med Chem (1998) 41:798-807.
-
(1998)
Crystallographic and Molecular Modeling Study of Complexes of 4-amino-4H-pyran-6carboxamides and Sialidase from Influenza Virus Types a and B. J Med Chem
, vol.41
, pp. 798-807
-
-
Taylor, N.R.1
-
81
-
-
0030963050
-
Synthesis of phosphonic acid analogues of siatic acids (NeuSAc and KDN) as potential sialidase inhibitors
-
Xin YC
-
Chan TH, Xin YC: Synthesis of phosphonic acid analogues of siatic acids (NeuSAc and KDN) as potential sialidase inhibitors. J Org Chem (1997) 62:3500-3504.
-
(1997)
J Org Chem
, vol.62
, pp. 3500-3504
-
-
Th Chan1
-
82
-
-
0026008031
-
Structural characteristics of the M2 protein of the influenza a viruses: Evidence that it forms a tetrameric channel
-
Hay AJ
-
Sugrue RJ, Hay AJ: Structural characteristics of the M2 protein of the influenza A viruses: evidence that it forms a tetrameric channel. V/ro/ogy (1991) 180:617-624.
-
(1991)
V/ro/ogy
, vol.180
, pp. 617-624
-
-
Sugrue, R.J.1
-
83
-
-
0026612385
-
Influenza virus M2 protein has ion channel activity
-
Holsinger LJ, Lamb RA
-
Pinto LH, Holsinger LJ, Lamb RA: Influenza virus M2 protein has ion channel activity. Cell (1992) 69:517-528.
-
(1992)
Cell
, vol.69
, pp. 517-528
-
-
Pinto, L.H.1
-
84
-
-
0026664025
-
Unpacking the incoming influenza virus
-
Helenius A: Unpacking the incoming influenza virus. Cell (1992) 69:577-578.
-
(1992)
Cell
, vol.69
, pp. 577-578
-
-
Helenius, A.1
-
85
-
-
0002988267
-
The action of adamantanamines against influenza a viruses: Inhibition of the M2 ion channel protein
-
Hay AJ: The action of adamantanamines against influenza A viruses: inhibition of the M2 ion channel protein. Semin V7ro/(1992) 3:21-30.
-
(1992)
Semin V7ro/
, vol.3
, pp. 21-30
-
-
Hay, A.J.1
-
86
-
-
84921425667
-
Influenza update: Influenza B virus now predominates in England and Wales
-
Anonymous: Influenza update: influenza B virus now predominates in England and Wales. Commun Dis Hep Wkly (1997) 7:65.
-
(1997)
Commun Dis Hep Wkly
, vol.7
, pp. 65
-
-
Anonymous1
-
87
-
-
0029915297
-
Ion channels formed by NB, an influenza B virus protein
-
Premkumar LS, Premkumar A, Ewart D, Cox GB, Gage PW
-
Sunstrom NA, Premkumar LS, Premkumar A, Ewart D, Cox GB, Gage PW: Ion channels formed by NB, an influenza B virus protein. J Membrane Biol (1996) 150:127-132.
-
(1996)
J Membrane Biol
, vol.150
, pp. 127-132
-
-
Sunstrom, N.A.1
-
88
-
-
0026478002
-
Potential agents in the treatment of influenza
-
Betts RF: Potential agents in the treatment of influenza. Curr Opin Infect Dis (1992) 5:811-815.
-
(1992)
Curr Opin Infect Dis
, vol.5
, pp. 811-815
-
-
Betts, R.F.1
-
90
-
-
0020534168
-
Differences in side effects of amantadine nydrochloride and rimantadine hydrochloride relate to differences in pharmacokinetics
-
Huffman HE, Spyler DA
-
Hayden FG, Huffman HE, Spyler DA: Differences in side effects of amantadine nydrochloride and rimantadine hydrochloride relate to differences in pharmacokinetics. Antimicrob Agents Chemother (1983) 23:458-464.
-
(1983)
Antimicrob Agents Chemother
, vol.23
, pp. 458-464
-
-
Hayden, F.G.1
-
91
-
-
0029119701
-
Ohmit SE, Hombuckle K, Pearve CL: Safety and efficacy of long-term use of rimantadine for prophylaxis of type a influenza in nursing homes
-
Monto AS. Ohmit SE, Hombuckle K, Pearve CL: Safety and efficacy of long-term use of rimantadine for prophylaxis of type A influenza in nursing homes. Antimicrob Agents Chemother (1995) 39:2224-2228.
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 2224-2228
-
-
Monto, A.S.1
-
92
-
-
0024819536
-
Emergence and apparent transmission of rimantadineresistant influenza a virus in families
-
Belshe RB, Clover RD, Hay AJ, Oakes M, Soo W
-
Hayden F, Belshe RB, Clover RD, Hay AJ, Oakes M, Soo W: Emergence and apparent transmission of rimantadineresistant influenza A virus in families. New Engl J Med (1989)321:1696-1702.
-
(1989)
New Engl J Med
, vol.321
, pp. 1696-1702
-
-
Hayden, F.1
-
93
-
-
0026332073
-
Resistance to rimantadine and amantadine
-
Betts RF: Resistance to rimantadine and amantadine. Curr Opin Infect Dis (1991 ) 4:804-808.
-
(1991)
Curr Opin Infect Dis
, vol.4
, pp. 804-808
-
-
Betts, R.F.1
-
94
-
-
0025815157
-
Recovery of drug-resistant influenza a virus during therapeutic use of rimantadine
-
Sperber SJ, Belshe RB, Clover RD, Hay AJ, Pyke S
-
Hayden FG, Sperber SJ, Belshe RB, Clover RD, Hay AJ, Pyke S: Recovery of drug-resistant influenza A virus during therapeutic use of rimantadine. Antimicrob Agents Chemother (1991) 35:1741-1747.
-
(1991)
Antimicrob Agents Chemother
, vol.35
, pp. 1741-1747
-
-
Hayden, F.G.1
-
95
-
-
0026002563
-
Gravenstein S, Wu SP, Arden NH, Circo R, Tyszka G, Kendal AP, Davis JP: Emergence and possible transmission of amantadine-resistant viruses during nursing home outbreaks of influenza a (H3N2)
-
Harmon MW.
-
Mast EE, Harmon MW. Gravenstein S, Wu SP, Arden NH, Circo R, Tyszka G, Kendal AP, Davis JP: Emergence and possible transmission of amantadine-resistant viruses during nursing home outbreaks of influenza A (H3N2). Am J Epidemiol (1991 ) 134:988-997.
-
(1991)
Am J Epidemiol
, vol.134
, pp. 988-997
-
-
Mast, E.E.1
-
96
-
-
0028887676
-
Novel assay for the influenza virus M2 channel activity
-
Rader RK, Marino MH, Forgey RW
-
Griffin K, Rader RK, Marino MH, Forgey RW: Novel assay for the influenza virus M2 channel activity. FEBS Lett (1995) 357:269-274.
-
(1995)
FEBS Lett
, vol.357
, pp. 269-274
-
-
Griffin, K.1
-
97
-
-
0029981017
-
-
Krystal M, Esposito K, Tang W, Kurt S
-
Hahnenberger KM, Krystal M, Esposito K, Tang W, Kurt S: Use of microphysiometry for anr.lysis of heterologous ion channels expressed in yeast Nature Biotechnol (1996) 14:880-883.
-
(1996)
Use of Microphysiometry for Anr.lysis of Heterologous Ion Channels Expressed in Yeast Nature Biotechnol
, vol.14
, pp. 880-883
-
-
Hahnenberger, K.M.1
-
98
-
-
0019890491
-
Structure of the hemagglutinfn membrane glycoprotein of influenza virus at 3 a resolution
-
Skehel JJ, Wiley DC
-
Wilson IA, Skehel JJ, Wiley DC: Structure of the hemagglutinfn membrane glycoprotein of influenza virus at 3 A resolution. Nature (1981) 289:366-373.
-
(1981)
Nature
, vol.289
, pp. 366-373
-
-
Wilson, I.A.1
-
99
-
-
18844470928
-
Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformation
-
Lee KH, Steinhauer DA, Stevens DJ, Skehel JJ, Wiley DC
-
Chen J, Lee KH, Steinhauer DA, Stevens DJ, Skehel JJ, Wiley DC: Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformation. Ce//(1998) 95:409-417.
-
(1998)
Ce//
, vol.95
, pp. 409-417
-
-
Chen, J.1
-
100
-
-
0023082135
-
The structure and function of the hemagglutinin membrane glycoprotein of influenza virus
-
Wiley DC, Skehel JJ: The structure and function of the hemagglutinin membrane glycoprotein of influenza virus. Annu Rev Biochem (1987) 56:365-394.
-
(1987)
Annu Rev Biochem
, vol.56
, pp. 365-394
-
-
Skehel Jj, W.D.C.1
-
101
-
-
0028089983
-
Flu virus invasion: Halfway there
-
Kim PS
-
Carr CM, Kim PS: Flu virus invasion: halfway there. Science (1994)266:234-236.
-
(1994)
Science
, vol.266
, pp. 234-236
-
-
Carr, C.M.1
-
102
-
-
0026492542
-
Membrane fusion
-
White JM: Membrane fusion. Science (1992) 258:917-924.
-
(1992)
Science
, vol.258
, pp. 917-924
-
-
White, J.M.1
-
103
-
-
0032979555
-
H-Dependent changes in photoaffinity labeling patterns on the H1 influenza hemagglutinin using an inhibitor of viral fusion
-
Yu KL, Dischino DD, Harte W, Deshpande M, Luo G, Colonno RJ, Meanwell NA, Krystal M: p
-
Cianci C, Yu KL, Dischino DD, Harte W, Deshpande M, Luo G, Colonno RJ, Meanwell NA, Krystal M: pH-Dependent changes in photoaffinity labeling patterns on the H1 influenza hemagglutinin using an inhibitor of viral fusion. J V/ro/(1999) 73:1785-1794.
-
(1999)
J V/ro/
, vol.73
, pp. 1785-1794
-
-
Cianci, C.1
-
104
-
-
0026175939
-
Comparison of complete amino acid sequences and receptor-binding properties among 13 serotypes of hemagglutinins of influenza a viruses
-
Aoyama T, Kalo H, Suzuki Y, Tateno Y, Nakajima K
-
Nobusawa E, Aoyama T, Kalo H, Suzuki Y, Tateno Y, Nakajima K: Comparison of complete amino acid sequences and receptor-binding properties among 13 serotypes of hemagglutinins of influenza A viruses. V/ro/ogx(1991) 182:475-485.
-
(1991)
V/ro/ogx
, vol.182
, pp. 475-485
-
-
Nobusawa, E.1
-
105
-
-
0023781872
-
Viral RNA polymerases
-
Nagata K
-
Ishihama A, Nagata K: Viral RNA polymerases. CRC Criti Rev Biochem (1988) 23:27-76.
-
(1988)
CRC Criti Rev Biochem
, vol.23
, pp. 27-76
-
-
Ishihama, A.1
-
106
-
-
0023445054
-
Genomlc RNAs of influenza viruses are held in a circular conformation in virions and in infected cells by a terminal panhandle
-
Parvin JD, Gupta S, Krystal M, Palese P
-
Hsu MT, Parvin JD, Gupta S, Krystal M, Palese P: Genomlc RNAs of influenza viruses are held in a circular conformation in virions and in infected cells by a terminal panhandle. Proc Nati Acad Sei USA (1987) 84:8140-8144.
-
(1987)
Proc Nati Acad Sei USA
, vol.84
, pp. 8140-8144
-
-
Hsu, M.T.1
-
107
-
-
0025268102
-
Purification and molecular structure of RNA polymerase from influenza virus A/PR8
-
Mukaigawa J, Yokoiyama A, Kato A, Ueda S, Nagata K, Krystal M, Nayak DP, Ishihama A
-
Honda A, Mukaigawa J, Yokoiyama A, Kato A, Ueda S, Nagata K, Krystal M, Nayak DP, Ishihama A: Purification and molecular structure of RNA polymerase from influenza virus A/PR8. J Biochem (1990) 1007:624-628.
-
(1990)
J Biochem
, vol.1007
, pp. 624-628
-
-
Honda, A.1
-
108
-
-
0002210298
-
Expression and replication of the influenza virus genome
-
Alonso-Caplen FV, Julkunen l, Katze MG
-
.. 107. Krug RM, Alonso-Caplen FV, Julkunen l, Katze MG: Expression and replication of the influenza virus genome. In: The Influenza Viruses, Krug RM (Ed), Plenum Press, New York(1989):89-152.
-
(1989)
: the Influenza Viruses, Krug RM (Ed), Plenum Press, New York
, pp. 89-152
-
-
Krug, R.M.1
-
109
-
-
0020060865
-
Cap-recognizing protein of influenza virus
-
Patzelt E, Kuechler E
-
Blaas D, Patzelt E, Kuechler E: Cap-recognizing protein of influenza virus. Virology (1982) 116:339-348.
-
Virology 1
, vol.982
, pp. 339-348
-
-
Blaas, D.1
-
110
-
-
0003839687
-
Role of two influenza virus core P proteins in recognizing cap 1 structures (m7GpppNm) on RNAs and in initiating RNA transcription
-
Broni BA, Krug RM
-
Ulmanen I, Broni BA, Krug RM: Role of two influenza virus core P proteins in recognizing cap 1 structures (m7GpppNm) on RNAs and in initiating RNA transcription. Proc Natl Acad Sei USA (1981) 78:7355-7359.
-
(1981)
Proc Natl Acad Sei USA
, vol.78
, pp. 7355-7359
-
-
Ulmanen, I.1
-
111
-
-
0029048936
-
Differential activation of the influenza virus polymerase via template RNA binding
-
Tiley L, Krystal M
-
Cianci C, Tiley L, Krystal M: Differential activation of the influenza virus polymerase via template RNA binding. J V7ro/(1995) 69:3995-3999.
-
(1995)
J V7ro/
, vol.69
, pp. 3995-3999
-
-
Cianci, C.1
-
112
-
-
0020827585
-
Molecular model of a eukaryotic transcription complex: Functions and movements of influenza P proteins during capped RNAprimed transcription
-
Ulmanen l, Krug RM
-
Braam J, Ulmanen l, Krug RM: Molecular model of a eukaryotic transcription complex: Functions and movements of influenza P proteins during capped RNAprimed transcription. Cell (1983) 34:609-618.
-
(1983)
Cell
, vol.34
, pp. 609-618
-
-
Braam, J.1
-
113
-
-
0019343607
-
Priming of influenza viral RNA transcription by capped heterologous RNAs
-
Krug RM: Priming of influenza viral RNA transcription by capped heterologous RNAs. Curr Top Microbiol Immunol (1981)93:125-150.
-
(1981)
Curr Top Microbiol Immunol
, vol.93
, pp. 125-150
-
-
Krug, R.M.1
-
114
-
-
0019394947
-
A unique cap (m'GppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription
-
Bouloy M, Ulmanen l, Krug RM
-
Plotch SJ, Bouloy M, Ulmanen l, Krug RM: A unique cap (m'GppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription. Cell (1981) 23:847-858.
-
(1981)
Cell
, vol.23
, pp. 847-858
-
-
Plotch, S.J.1
-
115
-
-
0028123774
-
Recombinant Influenza virus polymerase: Requirement of both 5' and 3' viral ends for endonuclease activity
-
Chung TOY, Butcher JA, Krystal M
-
Hagen M, Chung TOY, Butcher JA, Krystal M: Recombinant Influenza virus polymerase: requirement of both 5' and 3' viral ends for endonuclease activity. J Virol (1994) 68:15091515.
-
(1994)
J Virol
, vol.68
, pp. 15091515
-
-
Hagen, M.1
-
116
-
-
0028228459
-
Sequencespecific binding of the influenza virus RNA polymerase to sequences located at the 5' ends of the viral RNAs
-
Hagen M, Matthews JT, Krystal M
-
Tiley LS, Hagen M, Matthews JT, Krystal M: Sequencespecific binding of the influenza virus RNA polymerase to sequences located at the 5' ends of the viral RNAs. J Virol (1994)68:5108-5116.
-
(1994)
J Virol
, vol.68
, pp. 5108-5116
-
-
Tiley, L.S.1
-
117
-
-
0021112490
-
The inhibition of the RNA polymerase activity of influenza virus a by pyrophosphate analogues
-
Hutchinson DW
-
Cload PA, Hutchinson DW: The inhibition of the RNA polymerase activity of influenza virus A by pyrophosphate analogues. Nucleic Acids Res (1983) 11:5621-5628.
-
(1983)
Nucleic Acids Res
, vol.11
, pp. 5621-5628
-
-
Cload, P.A.1
-
118
-
-
0021257404
-
Mode of interference of trisodium phophonoformate (INN: Foscarnet sodium), with influenza virus mRNA synthesis
-
Datema R
-
Stridh S, Datema R: Mode of interference of trisodium phophonoformate (INN: foscarnet sodium), with influenza virus mRNA synthesis. Virology (1984) 135:293-296.
-
(1984)
Virology
, vol.135
, pp. 293-296
-
-
Stridh, S.1
-
119
-
-
0028846207
-
Inhibition of influenza virus transcription by 2'-deoxy-2'fluoroguanosine
-
Ellis M, Klumpp K, Court S, Ford M
-
Tisdale M, Ellis M, Klumpp K, Court S, Ford M: Inhibition of influenza virus transcription by 2'-deoxy-2'fluoroguanosine. Antimicrob Agents Chemother (1995) 39:2454-2458.
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 2454-2458
-
-
Tisdale, M.1
-
120
-
-
0028027404
-
Efficacy of 2'-deoxy-2'-fluororibosides against influenza a and B viruses in ferrets
-
Tisdale M, Russell S, Leone A, Sweet C
-
Jakeman KJ, Tisdale M, Russell S, Leone A, Sweet C: Efficacy of 2'-deoxy-2'-fluororibosides against influenza A and B viruses in ferrets. Antimicrob Agents Chemother (1994)38:1864-1867.
-
(1994)
Antimicrob Agents Chemother
, vol.38
, pp. 1864-1867
-
-
Jakeman, K.J.1
-
121
-
-
0030007129
-
Antiinfluenza virus activities of 4-substituted 2,4dioxobutanoic acid inhibitors
-
Seinick H, Wolanski B, Tomassini JE
-
Hastings JC, Seinick H, Wolanski B, Tomassini JE: Antiinfluenza virus activities of 4-substituted 2,4dioxobutanoic acid inhibitors. Antimicrob Agents Chemother (1996)40:1304-1307.
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 1304-1307
-
-
Hastings, J.C.1
-
122
-
-
0028945182
-
Isolation and structure of flutimide, a novel endonuclease inhibitor of influenza virus
-
Goetz MA, Liesch JM, Zink DL, Raghoobar SL, Helms GL, Singh SB
-
Hensens OD, Goetz MA, Liesch JM, Zink DL, Raghoobar SL, Helms GL, Singh SB: Isolation and structure of flutimide, a novel endonuclease inhibitor of influenza virus. Tetrahedron Lett (1995) 36:2005-2008.
-
(1995)
Tetrahedron Lett
, vol.36
, pp. 2005-2008
-
-
Hensens, O.D.1
-
123
-
-
0029990093
-
A novel antiviral agent which inhibits the endonuclease of influenza viruses
-
Davies ME, Hastings JC, Lingham R, Mpjena M, Raghoobar SL, Singh SB, Tkacz JS, Goetz MA
-
Tomassini JE, Davies ME, Hastings JC, Lingham R, Mpjena M, Raghoobar SL, Singh SB, Tkacz JS, Goetz MA: A novel antiviral agent which inhibits the endonuclease of influenza viruses. Antimicrob Agents Chemother (1996) 40:1189-1193.
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 1189-1193
-
-
Tomassini, J.E.1
-
124
-
-
0028205160
-
Biochemical studies on capped RNA primers identify a class of oligonudeotide inhibitors of the influenza virus RNA polymerase
-
Ciand C, Hagen M, Terry B, Matthews JT, Krystal M, Colonno RJ
-
Chung TOY, Ciand C, Hagen M, Terry B, Matthews JT, Krystal M, Colonno RJ: Biochemical studies on capped RNA primers identify a class of oligonudeotide inhibitors of the influenza virus RNA polymerase. Proc Naff Acad Sd USA (1994) 91:23722376.
-
(1994)
Proc Naff Acad Sd USA
, vol.91
, pp. 23722376
-
-
Chung, T.O.Y.1
-
125
-
-
0030785703
-
Differential effect of RNA substrates on influenza virus transcription
-
Colonno R, Krystal M
-
Cianci C, Colonno R, Krystal M: Differential effect of RNA substrates on influenza virus transcription. Virus Res (1997) 50:65-75.
-
(1997)
Virus Res
, vol.50
, pp. 65-75
-
-
Cianci, C.1
-
126
-
-
0029967647
-
DempsW RE, Darke PL, Kuo LC: Elucidation of basic mechanistic and kinetic properties of influenza endonuclease using chemically synthesized RNAs
-
Benseler F, Cole Jl_ Stahlhut MW.
-
Olsen DB, Benseler F, Cole Jl_ Stahlhut MW. DempsW RE, Darke PL, Kuo LC: Elucidation of basic mechanistic and kinetic properties of influenza endonuclease using chemically synthesized RNAs. J Bid Chem (1996) 271:7435-7439.
-
(1996)
J Bid Chem
, vol.271
, pp. 7435-7439
-
-
Olsen, D.B.1
-
127
-
-
0031575767
-
Specific inhibition of influenza virus RNA polymerase and nudeoprotein genes expression by liposomally encapsulated antisense phosphorothioate oligonucleotides: Penetration and localization of oligonucleotides in clone 76 cells
-
Takai K, Nakada S, Yokota T, Takaku H
-
Hatta T, Takai K, Nakada S, Yokota T, Takaku H: Specific inhibition of influenza virus RNA polymerase and nudeoprotein genes expression by liposomally encapsulated antisense phosphorothioate oligonucleotides: penetration and localization of oligonucleotides in clone 76 cells. Biochem Biophys Res Comm (1997) 232:545-549.
-
(1997)
Biochem Biophys Res Comm
, vol.232
, pp. 545-549
-
-
Hatta, T.1
-
128
-
-
0030886052
-
Inhibition of influenza viral polymerases by minimal viral RNA decoys
-
Oanetz S, Krystal M
-
Luo G, Oanetz S, Krystal M: Inhibition of influenza viral polymerases by minimal viral RNA decoys. J Gen Virol (1997) 79:2329-2333.
-
(1997)
J Gen Virol
, vol.79
, pp. 2329-2333
-
-
Luo, G.1
-
129
-
-
0024319381
-
Baytor NW, Wagner RR: Transcription-inhibition and RNA-binding domains of influenza a virus matrix protein mapped with anti-jdiotypic antibodies and synthetic peptides
-
Ye ZP. Baytor NW, Wagner RR: Transcription-inhibition and RNA-binding domains of influenza A virus matrix protein mapped with anti-jdiotypic antibodies and synthetic peptides. J ViroJ (1989) 63:3586-3594.
-
(1989)
J ViroJ
, vol.63
, pp. 3586-3594
-
-
Ye, Z.P.1
-
130
-
-
0029914173
-
Antiviral activity of influenza virus M1 zinc finger peptides
-
Judd AK, Sanchez A, Anastaskxi D, Bücher DJ
-
Nassar EH, Judd AK, Sanchez A, Anastaskxi D, Bücher DJ: Antiviral activity of influenza virus M1 zinc finger peptides. J Virol (1996) 70:8639-8644.
-
(1996)
J Virol
, vol.70
, pp. 8639-8644
-
-
Nassar, E.H.1
-
131
-
-
0031035794
-
In vivo anti-influenza virus activity of a zinc finger peptide
-
Sanchez A, Bucher DJ, Huffman JH, Bailey K, Sidwell RW
-
Judd AK, Sanchez A, Bucher DJ, Huffman JH, Bailey K, Sidwell RW: In vivo anti-influenza virus activity of a zinc finger peptide. Antimicrob Agents Chemother (1997) 41:687-692.
-
(1997)
Antimicrob Agents Chemother
, vol.41
, pp. 687-692
-
-
Judd, A.K.1
-
132
-
-
0027979897
-
Aprotinin aerosol treatment of Influenza and paramyxovirus bronchopneumonia of mice
-
Zhimov OP
-
Ovcharenko AV, Zhimov OP: Aprotinin aerosol treatment of Influenza and paramyxovirus bronchopneumonia of mice. Antiviral Res (1994) 23:107-118.
-
(1994)
Antiviral Res
, vol.23
, pp. 107-118
-
-
Ovcharenko, A.V.1
-
133
-
-
0028018138
-
-
Luo G, Palese P: Mutations at palmitylation sites of the influenza virus hemagglutinin affect virus formation. (1994) 68:5748-5754.
-
j 132. Zürcher T, Luo G, Palese P: Mutations at palmitylation sites of the influenza virus hemagglutinin affect virus formation. J Virol (1994) 68:5748-5754.
-
J Virol
-
-
Zürcher, T.1
-
134
-
-
0025076814
-
Palmitylation of the influenza a virus M2 protein
-
Belshe RB, Hay AJ
-
Sugrue RJ, Belshe RB, Hay AJ: Palmitylation of the influenza A virus M2 protein. Virology (1990) 79:51-56.
-
(1990)
Virology
, vol.79
, pp. 51-56
-
-
Sugrue, R.J.1
-
135
-
-
0030462522
-
Inhibition of glycoprotein processing by L-fructose and L-xylulose
-
Pan YT, Zeng Y, Atkins B, Izumori K, Elbein AD
-
Muniruzzaman S, Pan YT, Zeng Y, Atkins B, Izumori K, Elbein AD: Inhibition of glycoprotein processing by L-fructose and L-xylulose. G/ycofc/b/opy(1996) 6:795-803.
-
(1996)
G/ycofc/b/opy
, vol.6
, pp. 795-803
-
-
Muniruzzaman, S.1
-
136
-
-
0029861167
-
Inhibitory effects of recombinant manganese Superoxide dismutase on influenza virus infections in mice
-
Huffman JH, Bailey KW, Wong MH, Nimrod A, Panel A
-
Sidwell RW, Huffman JH, Bailey KW, Wong MH, Nimrod A, Panel A: Inhibitory effects of recombinant manganese Superoxide dismutase on influenza virus infections in mice. Antimicrob Agents Chemother (1996) 40:2626-2631.
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 2626-2631
-
-
Sidwell, R.W.1
-
137
-
-
0029130751
-
-
Jaskunas R, Blobel G, Palese P, Moroianu J
-
O'Neill RE, Jaskunas R, Blobel G, Palese P, Moroianu J: Nuclear import of influenza virus RNA can be mediated by viral nucleoprotein and transport factors required for protein import J Biol Chem (1995) 270:22701 -22704.
-
(1995)
Nuclear Import of Influenza Virus RNA Can Be Mediated by Viral Nucleoprotein and Transport Factors Required for Protein Import J Biol Chem
, vol.270
, pp. 22701-22704
-
-
O'Neill, R.E.1
-
138
-
-
0032472328
-
The influenza virus NEP (NS2 protein) mediates the nuclear export of viral ribonucleoproteins
-
Talon J, Palese P
-
O'Neill RE, Talon J, Palese P: The influenza virus NEP (NS2 protein) mediates the nuclear export of viral ribonucleoproteins. EMBO J(1998) 17:288-296.
-
(1998)
EMBO J
, vol.17
, pp. 288-296
-
-
O'Neill, R.E.1
-
139
-
-
0029833125
-
Evaluation of antiinfluenza effects of camstat in mice infected with nonadapted human influenza viruses
-
Kirn KH, Park KY, Kim JS
-
Lee MG, Kirn KH, Park KY, Kim JS: Evaluation of antiinfluenza effects of camstat in mice infected with nonadapted human influenza viruses. Arch Virol (1996) 141:1979-1989.
-
(1996)
Arch Virol
, vol.141
, pp. 1979-1989
-
-
Lee, M.G.1
-
140
-
-
0030454382
-
Aerosolozed aprotinin is an effective drug against viral respiratory illness
-
Kirshner LA, Ovcherenko AV, Malyshev NA
-
Zhimov OP, Kirshner LA, Ovcherenko AV, Malyshev NA: Aerosolozed aprotinin is an effective drug against viral respiratory illness. Antiinfect Drugs Chemother (1996) 14:209-216.
-
(1996)
Antiinfect Drugs Chemother
, vol.14
, pp. 209-216
-
-
Zhimov, O.P.1
-
141
-
-
0029979051
-
Antiviral properties of extract of Opuntia streptacantha
-
Davies J, Randall S, Skinner GRB
-
Ahmad A, Davies J, Randall S, Skinner GRB: Antiviral properties of extract of Opuntia streptacantha. Antiviral Res (1996)30:75-85.
-
(1996)
Antiviral Res
, vol.30
, pp. 75-85
-
-
Ahmad, A.1
-
142
-
-
0032007379
-
In vitro anti-influenza virus activity of a plant preparation from Geranium sangulneum L
-
Hay AJ: (199) 37:121-130.
-
Serkedjieva J, Hay AJ: In vitro anti-influenza virus activity of a plant preparation from Geranium sangulneum L. Antiviral Research (199) 37:121-130.
-
Antiviral Research
-
-
Serkedjieva, J.1
-
143
-
-
15144353021
-
Two new lignans with activity against influenza virus from the medicinal plant Rhinacanthus nasutus
-
Ssndl A, Chen JL, Jolad SD, Blanc P, Murphy JT, Stoddart CA, Nanakom W, Balick MJ, Rozhon EJ
-
Keman MR, Ssndl A, Chen JL, Jolad SD, Blanc P, Murphy JT, Stoddart CA, Nanakom W, Balick MJ, Rozhon EJ: Two new lignans with activity against influenza virus from the medicinal plant Rhinacanthus nasutus. J Nat Prod (1997) 60:635-637.
-
(1997)
J Nat Prod
, vol.60
, pp. 635-637
-
-
Keman, M.R.1
-
144
-
-
0031035084
-
Glycyrrhizin, an active component of licorice roots, reduces morbidity and mortality of mice infected with lethal doses of influenza virus
-
Kobayashi M, Pollard RB, Suzuki F
-
Utsunomiya T, Kobayashi M, Pollard RB, Suzuki F: Glycyrrhizin, an active component of licorice roots, reduces morbidity and mortality of mice infected with lethal doses of influenza virus. Antimicmb Agents Chemother(\997) 41:551-556.
-
Antimicmb Agents Chemother\
, vol.997
, pp. 551-556
-
-
Utsunomiya, T.1
-
145
-
-
0027412541
-
SP-303 small particle aerosol treatment of influenza a virus infection in mice and respiratory syncytial virus infection in cotton rats
-
Wyde PR, Wilson SZ, Meyerson LR
-
Gilbert BE, Wyde PR, Wilson SZ, Meyerson LR: SP-303 small particle aerosol treatment of influenza A virus infection in mice and respiratory syncytial virus infection in cotton rats. Antiviral Res (1993) 21:37-45.
-
(1993)
Antiviral Res
, vol.21
, pp. 37-45
-
-
Gilbert, B.E.1
-
146
-
-
0029420438
-
Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nlgra L) during an outbreak of Influenza B Panama
-
Varsano N, Zlotnik M, Manor O, Regev L, Schlesinger M, Mumcuoglu M
-
Zakey-Rones Z, Varsano N, Zlotnik M, Manor O, Regev L, Schlesinger M, Mumcuoglu M: Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nlgra L) during an outbreak of Influenza B Panama. J Altem Complement Med (1995) 1:361-369.
-
(1995)
J Altem Complement Med
, vol.1
, pp. 361-369
-
-
Zakey-Rones, Z.1
-
147
-
-
33749780271
-
-
References to patent literature 201. BioCRYST PHARMACEUTICAL INC (Babu YS, Chand P, Walsh DA): Substituted benzene derivatives useful as neuraminidase inhibitors. WO-09630329 (1996)
-
References to patent literature 201. BioCRYST PHARMACEUTICAL INC (Babu YS, Chand P, Walsh DA): Substituted benzene derivatives useful as neuraminidase inhibitors. WO-09630329 (1996).
-
-
-
-
150
-
-
33749719313
-
-
WO-09806712 (1998).
-
SANKYO Co LTD (Honda T, Kobayashi Y, Yamshita M): Neuraminic acid compounds. WO-09806712 (1998).
-
Neuraminic Acid Compounds.
-
-
|