Design and synthesis of benzoic acid derivatives as influenza neuraminidase inhibitors using structure-based drug design

Journal of Medicinal Chemistry

Volumn 40, Issue 25, 1997, Pages 4030-4052

  Chand, Pooran ^a   Babu, Yarlagadda S ^a   Bantia, Shanta ^a   Chu, Naiming ^a   Cole, L Brent ^a   Kotian, Pravin L ^a   Laver, W Graeme ^a,b   Montgomery, John A ^a   Pathak, Ved P ^a,c   Petty, Sandra L ^a   Shrout, David P ^a   Walsh, David A ^a   Walsh, Gerald M ^a  

^a BIOCRYST PHARMACEUTICALS INC   (United States)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^c Alanex Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (ACETYLAMINO) 3 GUANIDINOBENZOIC ACID; BENZOIC ACID DERIVATIVE; SIALIDASE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; INFLUENZA; NONHUMAN; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VIRUS INHIBITION;

ANIMALS; ANTIVIRAL AGENTS; BENZOATES; BENZOIC ACID; DRUG DESIGN; ENZYME INHIBITORS; FEMALE; MICE; MICE, INBRED BALB C; NEURAMINIDASE; ORTHOMYXOVIRIDAE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 15144343348     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970479e     Document Type: Article

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