Effect of diet and nutrition on the expression of cytochromes P450

Xenobiotica

Volumn 29, Issue 2, 1999, Pages 109-154

  Ioannides, Costas ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETANILIDE; ALCOHOL; ANTHRAFLAVIC ACID; CAPSAICIN; CYCLOSPORIN; CYTOCHROME P450; ERYTHROMYCIN; ETHOXYRESORUFIN; FLAVONOID; MINERAL; ORGANOSULFUR DERIVATIVE; PHENACETIN; PHENOBARBITAL; PSORALEN; RETINOL; SAFROLE; TERPENOID; THEOPHYLLINE; VITAMIN; WARFARIN; XENOBIOTIC AGENT;

CALORIC INTAKE; COOKING; DEMETHYLATION; DIET; DIETARY FIBER; DRUG BLOOD LEVEL; DRUG METABOLISM; ENZYME ACTIVITY; FAT INTAKE; FRUIT JUICE; HUMAN; METABOLISM; NONHUMAN; NUTRITION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INTAKE; REVIEW; TEA; VEGETABLE; XENOBIOTIC METABOLISM;

EID: 0032964849     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/004982599238704     Document Type: Review

References (238)

1. ALVARES, A. P., ANDERSON, K. E., CONNEY, A. H. and KAPPAS, A., 1976, Interactions between nutritional factors and drug biotransformation in man. Proceedings of the National Academy of Sciences, USA, 73, 2501-2504.
2. AMEER, B. and WEINTRAUB, R. A., 1997, Drug interactions with grapefruit juice. Clinical Pharmacokinetics, 33, 103-121.
3. ANDERSON, K. E., MCLEERY, R. B., VESELL, E. S., VICKERS, F. F. and KAPPAS, A., 1991, Diet and cimetidine induce comparable changes in theophylline metabolism in normal subjects. Hepatology, 13, 941-946.
4. ARCE, D. S. and KEEN, C. L., 1992, Reversible and persistent consequences of copper deficiency in developing mice. Reproductive Toxicology, 6, 211-221.
5. ASTORG, P., GRADELET, S., LECLERC, J., CANIVENC, M.-C. and SIESS, M.-H., 1994, Effects of β-carotene and canthaxanthin on liver xenobiotic-metabolizing enzymes in the rat. Food and Chemical Toxicology, 32, 735-742.
6. AUSTIN, C. A., SHEPHARD, E. A., PIKE, S. F., RABIN, B. R. and PHILLIPS, I. R., 1988, The effect of terpenoid compounds on cytochrome P-450 levels in rat liver. Biochemical Pharmacology, 37, 2223-2229.
7. AYALOGU, E. O., PHILLIPSON, C. E., PREECE, N., IOANNIDES, C. and PARKE, D. V., 1988, Effect of vitamin A on rat hepatic mixed-function oxidases, glutathione transferase activity and generation of oxygen radicals. Annals of Nutrition and Metabolism, 32, 75-82.
8. AYALOGU, E. O., SNELLING, J., LEWIS, D. F. V., TALWAR, S., CLIFFORD, M. N. and IOANNIDES, C., 1995, Induction of hepatic CYP1A2 by the oral administration of caffeine to rats: lack of association with the Ah locus. Biochimica et Biophysica Acta, 1272, 89-94.
9. AYRTON, A. D., IOANNIDES, C. and WALKER, R., 1988a, Induction of rat hepatic cytochrome P-4501 proteins by the antimutagen anthraflavic acid. Food and Chemical Toxicology, 26, 909-915.
10. AYRTON, A. D., TRINICK, J., WOOD, B. P., SMITH, J. N. and IOANNIDES, C., 1988b, Induction of the rat hepatic microsomal mixed-function oxidases by two aza-arenes. A comparison with their non-heterocyclic analogues. Biochemical Pharmacology, 37, 4565-4571.
11. BAILEY, D. G., ARNOLD, J. M. O., STRONG, H. A., MUNOZ, C. and SPENCE, J. D., 1993a, Effect of grapefruit and naringin on nisoldipine pharmacokinetics. Clinical Pharmacology and Therapeutics, 54, 589-594.
12. BAILEY, D. G., ARNOLD, J. M. O., MUNOZ, C. and SPENCE, J. D., 1993b, Grapefruit-felodipine drug interaction, mechanism, predictability and effect of naringin. Clinical Pharmacology and Therapeutics, 53, 637-642.
13. BAILEY, D. G., SPENCE, J. D., MUNOZ, C. and ARNOLD, J. M. O., 1991, Interaction of citrus juices with felodipine and nifedipine. Lancet, 337, 268-269.
14. BARCELO, S., GARDINER, J. M., GESCHER, A. and CHIPMAN, J. K., 1996, CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane. Carcinogenesis, 17, 277-282.
15. BARNETT, C. R., FLATT, P. R. and IOANNIDES, C., 1988, Role of ketone bodies in the diabetes-induced changes in hepatic mixed-function oxidase activities. Biochimica et Biophysica Acta, 967, 250-254.
16. BARNETT, C. R., FLATT, P. R. and IOANNIDES, C., 1990a, Induction of hepatic microsomal P450I and IIB proteins by hyperketonaemia. Biochemical Pharmacology, 40, 393-397.
17. BARNETT, C. R., GIBSON, G. G., WOLF, C. R., FLATT, P. R. and IOANNIDES, C., 1990b, Induction of cytochrome P450III and P450IV family proteins in streptozotocin-induced diabetes. Biochemical Journal, 268, 765-769.
18. BARNETT, C. R., PETRIDES, L., WILSON, J., FLATT, P. R. and IOANNIDES, C., 1992, Induction of rat hepatic mixed-function oxidases by acetone and other physiological ketones: their role in diabetes-induced changes in cytochrome P450 proteins. Xenobiotica, 22, 1441-1450.
19. BARONE, J. J. and ROBERTS, H. R., 1996, Caffeine consumption. Food and Chemical Toxicology, 34, 119-129.
20. BENTON, R. E., HONIG, P. K., ZAMANI, K., CANTILENA, L. R and WOOSLEY, R. L., 1996, Grapefruit juice alters terfenadine pharmacokinetics, resulting in prolongation of repolarization on the electrocardiogram. Clinical Pharmacology and Therapeutics, 59, 383-388.
21. BJELDANES, L. F., KIM, J.-Y., GROSE, K. R., BARTHOLOMEW, J. C. and BRADFIELD, C. A., 1991, Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Proceedings of the National Academy of Sciences, USA, 88, 9543-9547.
22. BRADFIELD, C. A. and BJELDANES, L. F., 1987, Structure-activity relationships of dietary indoles: a proposed mechanism of action as modifiers of xenobiotic metabolism. Journal of Toxicology and Environmental Health, 21, 311-323.
23. BRADFIELD, C. A., CHANG, Y. and BJELDANES, L. F., 1985, Effects of commonly consumed vegetables on hepatic xenobiotic-metabolizing enzymes in the mouse. Food and Chemical Toxicology, 23, 899-904.
24. BRADY, J. F., ISHIZAKI, H., FUKUTO, J. M., LIN, M. C., FADEL, A., GAPAC, J. M. and YANG, C. S., 1991b, Inhibition of cytochrome P-450 2E1 by diallyl sulfide and its metabolites. Chemical Research in Toxicology, 4, 642-647.
25. BRADY, J. F., WANG, M.-H., HONG, J.-Y., XIAO, F., LI, Y., YOO, J.-S., NING, S. M., FUKUTO, J. M., GAPAC, J. M. and YANG, C. S., 1991a, Modulation of rat hepatic microsomal monooxygenase activities and cytotoxicity by diallyl sulfide. Toxicology and Applied Pharmacology, 108, 342-354.
26. BROWN, B. L., ALLIS, J. W., SIMMONS, J. E. and HOUSE, D. E., 1995, Fasting for less than 24 h induces cytochrome P450 2E1 and 2B1/2 activities in rats. Toxicology Letters, 81, 39-44.
27. BU-ABBAS, A., CLIFFORD, M. N., WALKER, R. and IOANNIDES, C., 1994, Selective induction of rat hepatic CYP1 and CYP4 proteins and of peroxisomal proliferation by green tea. Carcinogenesis, 15, 2575-2579.
28. BU-ABBAS, A., COPELAND, E., CLIFFORD, M. N., WALKER, R. and IOANNIDES, C., 1998, Cytochrome P450 induction by tea and its consequences on the bioactivation of chemical carcinogens: contribution of caffeine and flavanols. Environmental Toxicology and Pharmacology (in press).
29. BUTLER, L. E. and DAUTERMAN, W. C., 1989, Sensitivity of selected drug biotransformation enzymes to dietary protein levels in adult F334 male rats. Journal of Biochemical Toxicology, 4, 71-72.
30. BUTLER, M. A., IWASAKI, M., GUENGERICH, F. P. and KADLUBAR, F. F., 1989, Human cytochrome P450PA (P-450IA2), the phenacetin deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines. Proceedings of the National Academy of Sciences, USA, 86, 7696-7700.
31. CAMPBELL, T. C. and HAYES, J. R., 1976, The effect of quantity and quality of dietary protein on drug metabolism. Federation Proceedings, 35, 2470-2474.
32. CANIVENC-LAVIER, M.-C., BENTEJAC, M., MILLER, M-L., LECLERC, J., SIESS, M.-H., LATRUFFE, N. and SUSCHETET, M., 1996b, Differential effects of nonhydroxylated flavonoids as inducers of cytochrome P450 1A and 2B isozymes in rat liver. Toxicology and Applied Pharmacology, 136, 348-353.
33. CANIVENC-LAVIER, M.-C., VERNEVAUT, M.-F., TOTIS, M., SIESS, M.-H., MAGDALOU, J. and SUSCHETET, M., 1996a, Comparative effects of flavonoids and model inducers on drug-metabolizing enzymes in rat liver. Toxicology, 114, 19-27.
34. CARPENTER, M. R. and HOWARD, C. N., 1974, Vitamin E, steroids and liver microsomal hydroxylations. American Journal of Clinical Nutrition, 27, 966-979.
35. CHANG, T. K. H. and WAXMAN, D. J., 1996, The CYP2A subfamily. In C. Ioannides (ed.), Cytochromes P450: Metabolic and Toxicological Aspects (Boca Raton: CRC Press), pp. 99-134.
36. CHEN, L., BONDOC, F. Y., LEE, M.-J., HUSSIN, A. H. J., THOMAS, P. E. and YANG, C. S., 1996, Caffeine induces cytochrome P4501A2: induction of CYP1A2 by tea in rats. Drug Metabolism and Disposition, 24, 529-533.
37. CHOU, M. W., KONG, J., CHUNG, K.-T. and HART, R. W., 1993, Effect of caloric restriction on the metabolic activation of xenobiotics. Mutation Research, 295, 223-235.
38. COHEN, L. A., 1987, Diet and cancer. Scientific American, 257, 42-48.
39. CONNEY, A. H., PANTUCK, E. J., HSIA, K. C., GARLAND, W. A., ANDERSON, K. E., ALVARES, A. P. and KAPPAS, A., 1976, Enhanced phenacetin metabolism in human subjects fed charcoal-broiled beef. Clinical Pharmacology and Therapeutics, 20, 633-642.
40. CONNEY, A. H., PANTUCK, E. J. KUNTZMAN, R., KAPPAS, A., ANDERSON, K. E. and ALVARES, A. P., 1977, Nutrition and chemical biotransformation in man. Clinical Pharmacology and Therapeutics, 22, 707-719.
41. CORREIA, M. A. and BURK, R. F., 1978, Rapid stimulation of hepatic microsomal heme oxygenase in selenium-deficient rats. Journal of Biological Chemistry, 253, 6203-6210.
42. DE KRUIF, C. A., MARSMAN, J. W., VENEKAMP, J. C., NOORDHOEK, J., BLAAUBOER, B. J. and WORTELBOER, H. M., 1991, Structure elucidation of acid reaction products of indole-3-carbinol: detection in vivo and enzyme induction in vitro. Chemico-Biological Interactions, 80, 303-315.
43. DEGAWA, M., KOBAYASHI, K.-I., MIURA, S.-I., ARAI, H., ESUMI, H., SUGIMURA, T. and HASHIMOTO, Y., 1992, Species difference among experimental rodents in induction of P450IA family enzymes by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Japanese Journal of Cancer Research, 83, 1047-1051.
44. 2+-stimulated ATPase and drug oxidase activities of guinea pigs by dietary cholesterol. Biochemical Pharmacology, 32, 1309-1312.
45. DHUR, A., GALAN, P. and HEREBFRG, S., 1989, Effects of different degrees of iron deficiency on cytochrome P450 complex and pentose phosphate pathway dehydrogenases in the rat. Journal of Nutrition, 119, 40-47.
46. DRAGNEV, K. H., NIMS, R. W. and LUBERT, R. A., 1995, The chemopreventive agent diallyl sulfide. A structurally atypical phenobarbital-type inducer. Biochemical Pharmacology, 50, 2099-2104.
47. DUCHARME, M. D., WARBASSE, L. H. and EDWARDS, D. J., 1995, Disposition of intravenous and oral cyclosporine after administration with grapefruit juice. Clinical Pharmacology and Therapeutics, 57, 485-491.
48. EDWARDS, D. J., BELLEVUE III, F. H. and WOSTER, P. M., 1996, Identification of 6′,7′-dihydroxy-bergamottin, a cytochrome P450 inhibitor, in grapefruit juice. Drug Metabolism and Disposition, 24, 1287-1290.
49. ESTABROOK, R. W., 1996, Cytochrome P450: from a single protein to a family of proteins - with some personal reflections. In C. Ioannides (ed.), Cytochromes P450: Metabolic and Toxicological Aspects (Boca Raton: CRC Press), pp. 3-28.
50. FAGAN, T. C., WALLE, T., OEXMANN, M. J., WALLE, U. K., BAI, S. A. and GAFNY, T. E., 1987, Increased clearance of propranolol and theophylline by high-protein compared with high-carbohydrate diet. Clinical Pharmacology and Therapeutics, 41, 402-406.
51. FUHR, U., DOEHMER, J., BATTULA, N., WÖLFEL, C., KUDLA, C., KEITA, Y. and STAIB, A. H., 1992, Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms. Biochemical Pharmacology, 43, 225-235.
52. FUHR, U., KLITTICH, K. and STAIB, A. H., 1993, Inhibitory effect of grapefruit juice and the active component, naringetin, on CYP1A2 dependent metabolism of caffeine. British Journal of Clinical Pharmacology, 35, 431-436.
53. FUHR, U., MAIER, A., KELLER, A., STEINJUANS, V. W., SAUTER, R. and STAIB, A. H., 1995, Lacking effect of grapefruit juice on theophylline pharmacokinetics. International Journal of Clinical Pharmacology and Therapeutics, 33, 311-314.
54. FULLERTON, F. R., GREENMAN, D. L., MCCARTY, M. M. and BUCCI, T. J., 1991, Increased incidence of spontaneous and 2-acetylaminofluorene-induced liver and bladder tumors inn B6C3F1 mice fed AIN-76A diet versus NIH-07 diet. Fundamental and Applied Toxicology, 16, 51-60.
55. GHOSH, S. S., BASU, A. K., GHOSH, S., HAGLEY, R., KRAMER, L., SCUETZ, J., GROGAN, W. MC., GUZELIAN, P. and WATLINGTON, C. O., 1995, Renal and hepatic family 3A cytochromes P450 (CYP3A) in spontaneously hypertensive rats. Biochemical Pharmacology, 50, 49-54.
56. GILLNER, M., BERGMAN, J., CAMBILAU, C., FERNSTRÖM, B. and GUSTAFSSON, J. A., 1985, Interaction of indoles with binding sites for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver. Molecular Pharmacology, 28, 357-363.
57. GLUSKER, J. P. and ROSSI, M., 1986, Molecular aspects of chemical carcinogens and bioflavonoids. In V. Cody, E. Middleton and J. B. Harborne (eds), Plant Flavonoids in Biology and Medicine: Biochemical, Pharmacological, and Structure-Activity Relationships (New York: Alan R. Liss), pp. 395-410.
58. GOASDUFF, T., DRÉANO, Y., GUILLOIS, B., MÉNDEZ, J.-F. and BERTHOU, F., 1996, Induction of liver and kidney CYP1A1/1A2 by caffeine in rat. Biochemical Pharmacology, 52, 1915-1919.
59. GONZALEZ, F. J., 1992, Human cytochromes P450: problems and prospects. Trends in Pharmacological Sciences, 13, 346-352.
60. GONZALEZ, F. J., 1996, The CYP2D subfamily. In C. Ioannides (ed.), Cytochromes P450: Metabolic and Toxicological Aspects (Boca Raton: CRC Press), pp. 183-210.
61. GONZALEZ, F. J. and GELBOIN, H. V., 1994, Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins. Drug Metabolism Reviews, 26, 165-183.
62. GHADELET, S., ASTORG, P., LECLERC, J., CHEVALIER, J., VERNEVAUT, M. F. and SIESS, M.-H., 1996b, Effects of canthaxanthin, astaxanthin, lycopene and lutein on liver xenobiotic-metabolizing enzymes in the rat. Xenobiotica, 26, 49-63.
63. GHADELET, S., ASTORG, P., LECLERC, J. and SIESS, M.-H., 1996a, β-apo-8′'-carotenal, but not β-carotene, is a strong inducer of liver CYP1A1 and 1A2 in the rat. Xenobiotica, 26, 909-919.
64. GRADELET, S., ASTORG, P., PINEAU, T., CANIVENC, M.-C., SIESS, M.-H., LECLERC, J. and LESCA, P., 1997, Ah receptor-dependent CYP1A induction by two carotenoids, canthaxanthin and β-apo-8′-carotenal, with no affinity for the TCDD binding site. Biochemical Pharmacology, 54, 307-315.
65. GROSSE, W. and WADE, A. E., 1971, The effect of thiamine consumption on liver microsomal drug-metabolizing pathways. Journal of Pharmacology and Experimental Therapeutics, 176, 758-765.
66. GUENGERICH, F. P., 1984, Effects of nutritive factors on metabolic processes involving bioactivation and detoxication of chemicals. Annual Reviews in Nutrition, 4, 207-231.
67. GUENGERICH, F. P. and KIM, D. H., 1990, In vitro inhibition of dihydropyridine oxidation and aflatoxin B1 activation in human liver microsomes by naringetin and other flavonoids. Carcinogenesis, 11, 2275-2279.
68. GUO, Z., SMITH, T. J., WANG, E., SADRIEH, N., MA, Q., THOMAS, P. E. and YANG, C. S., 1992, Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotic-metabolizing enzymes and nitrosamme metabolism in rats. Carcinogenesis, 13, 2205-2210.
69. GWANG, J. H., 1996, Induction of rat hepatic cytochrome P4501A and P4502B by the methoxsalen. Cancer Letters, 108, 115-120.
70. HABER, D., SIESS, M.-H., DE WAZIERS, I., BEAUNE, P. and SUSCHETET, M., 1994, Modification of hepatic drug-metabolizing enzymes in rats fed naturally occurring allyl sulphides. Xenobiotica, 24, 169-182.
71. HAKKAK, R., KOROUNIAN, S., RONIS, M. J., INGELMAN-SUNDBERG, M. and BADGER, T. M., 1996, Effects of diet and ethanol on the expression and localization of cytochromes P450 2E1 and P450 2C7 in the colon of male rats. Biochemical Pharmacology, 51, 61-69.
72. HAMMERMUELLER, J. D., BRAY, T. M. and BETTGER, W. J., 1987, Effect of zinc and copper deficiency on microsomal NADPH-dependent active oxygen generation in rat liver. Journal of Nutrition, 117, 894-901.
73. HARTSHORN, R. D., DEMERS, L. M., SULTATOS, L. G., VESELL, E. S., MAXLANG, C. and HUGHES, C. H. JR, 1979, Effects of chronic parenteral carbohydrate administration on hepatic drug metabolism in the rat. Pharmacology, 18, 103-111.
74. HASHMI, R., SIDDIQUI, A. M., KACHOLE, M. S. and PAWAR, S. S., 1986, Alterations in hepatic microsomal mixed-function oxidase system during different levels of food restriction in adult male and female rats. Journal of Nutrition, 116, 682-688.
75. HELLER, R. F., HENRY, D. A. and BRENT, P. J., 1989, Enzyme induction by eating charcoal-grilled steak with no effect of blood lipids. Clinical and Experimental Pharmacology and Physiology, 16, 783-788.
76. HIETANEN, E., AHOTUPA, M., BEREZIAT, J., PARK, S. S., GELBOIN, H. V. and BARTSCH, H., 1987, Monoclonal antibody characterization of hepatic and extrahepatic cytochrome P450 activities in rats treated with phenobarbital or methylcholanthrene and fed various cholesterol diets. Biochemical Pharmacology, 36, 3973-3980.
77. HIETANEN, E., LAITINEN, M., VAINIO, H. and HANNINEN, O., 1975, Dietary fats and properties of endoplasmic reticulum. II. Dietary lipid induced changes in activities of drug metabolising enzymes in liver and duodenum of rats. Lipids, 10, 467-472.
78. HOENSCH, H., WOO, C. H. and SCHMID, R., 1975, Cytochrome P-450 and drug metabolism in intestinal villous and crypt cells of rats: effect of dietary iron. Biochemical and Biophysical Research Communications, 65, 399-406.
79. HONG, J., PANG, J., GONZALEZ, F. J., GELBOIN, H. V. and YANG, C. S., 1987a, The induction of a specific form of cytochrome P-450 (P-450j) by fasting. Biochemical and Biophysical Research Communications, 142, 1077-1083.
80. HONG, J.-Y., PAN, J., DONG, Z., NING, S. M. and YANG, C. S., 1987b, Regulation of N-nitro-somethylamine demethylase in rat liver and kidney. Cancer Research, 47, 5948-5953.
81. HONG, Y.-S., 1997, Effect of diallyl sulfide on tetrachlorodibenzo-p-dioxin-induced cytochrome P-450 1Al gene in mouse lung. Biochemical Archives, 13, 179-187.
82. HOWELL, S. R., SHIRLEY, M. A. and ULM, E. H., 1998, Effects of retinoid treatment of rats on hepatic microsomal metabolism and cytochromes P450. Drug Metabolism and Disposition, 26, 234-239.
83. HUANG, O., LAWSON, T. A., CHUNG, F. L., MORRIS, C. R. and MIRVISH, S. S., 1993, Inhibition by phenylethyl and phenylhexyl isothiocyanates of metabolism and DNA methylation by N-nitrosomethylamylamine in rats. Carcinogenesis, 14, 749-754.
84. HULLA, J. E. and JUCHAU, M. R., 1989, Developmental aspects of P450IIIA: prenatal activity and inducibility. Drug Metabolism Reviews, 20, 765-779.
85. IMAOKA, S., TERANO, Y. and FUNAE, Y., 1990a, Changes in the amount of cytochromes P450 in rat hepatic microsomes with starvation. Archives of Biochemistry and Biophysics, 278, 168-178.
86. IMAOKA, S., TERANO, Y. and FUNAE, Y., 1990b, Induction and regulation of cytochrome P450 K-5 (lauric acid hydroxylase) in rat renal microsomes by starvation. Biochimica et Biophysica Acta, 1036, 18-23.
87. IOANNIDES, C., DELAFORGE, M. and PARKE, D. V., 1981, Safrole: its metabolism, carcinogenicity and interactions with cytochrome P-450. Food and Cosmetics Toxicology, 19, 657-666.
88. IOANNIDES, C., DELAFORGE, M. and PARKE, D. V., 1985, Interactions of safrole and isosafrole and their metabolites with cytochromes P-450. Chemico-Biological Interactions, 53, 303-311.
89. IOANNIDES, C., BARNETT, C. R., IRIZAR, A. and FLATT, P. R., 1996, Expression of cytochrome P450 proteins in disease. In C. Ioannides (ed.), Cytochromes P450: Metabolic and Toxicological Aspects (Boca Raton: CRC Press), pp. 301-327.
90. IOANNIDES, C. and PARKE, D. V., 1990, The cytochrome P450I gene family of microsomal haemoproteins and their role in the metabolic activation of chemicals. Drug Metabolism Reviews, 22, 1-85.
91. IOANNIDES, C. and STEELE, C. M., 1986, Hepatic microsomal mixed-function oxidase activity in ethanol treated hamsters and its consequences on the bioactivation of aromatic amines to mutagens. Chemico-Biological Interactions, 59, 129-139.
92. IRIZAR, A. and IOANNIDES, C., 1998, Marked inhibition of hepatic cytochrome P450 activity in cholesterol-induced atherosclerosis in mice. Toxicology, 126, 179-193.
93. ISHIZAKI, H., BRADY, J. F., NING, S. M. and YANG, C. S., 1990, Effect of phenethyl isothiocyanate on microsomal N-nitrosodimethylamine (NDMA) metabolism and other monooxygenase activities. Xenobiotica, 20, 255-264.
94. JANECZKO, R., WAXMAN, D. J., LE BLANC, G. A., MORVILLE, A. and ADESNIK, M., 1990, Hormonal regulation of levels of the messenger RNA encoding hepatic P450 2c (IIC11), a constitutive male-specific form of cytochrome P450. Molecular Endocrinology, 4, 295-303.
95. JELLINCK, P. H., FORKERT, P. G., RIDDICK, D. S., OKEY, A. B., MICHNOVICZ, J. J. and BRADLOW, H. L., 1993, Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation. Biochemical Pharmacology, 45, 1129-1136.
96. JIN, L. and BAILLIE, T. A., 1997, Metabolism of the chemopreventive agent diallyl sulphide to glutathione conjugates in rats. Chemical Research in Toxicology, 10, 318-327.
97. JOHANSSON, I., EKSTRÖM, G., SCHÖLTE, B., PUZYCKI, B., JORNVALL, H. and INGELMAN-SUNDBERG, M., 1988, Ethanol-, fasting- and ethanol-inducible cytochromes P-450 in rat liver: Regulation and characteristics of enzymes belonging to the IIB and IIE gene subfamilies. Biochemistry, 27, 1925-1934.
98. JOHANSSON, I., LINDROS, K. O., ERIKSSON, H. and INGELMAN-SUNDBERG, M., 1990, Transcriptional control of CYP2E1 in the perivenous liver region and during starvation. Biochemical and Biophysical Research Communications, 173, 331-338.
99. KALL, M. A. and CLAUSEN, J., 1995, Dietary effect on mixed function P450 1A2 activity assayed by estimation of caffeine metabolism in man. Human and Experimental Toxicology, 14, 801-807.
100. KALL, M. A., VANG, O. and CLAUSEN, J., 1996, Effects of dietary broccoli on human in vivo drug metabolizing enzymes: evaluation of caffeine, oestrone and chlorzoxazone metabolism. Carcinogenesis, 17, 793-799.
101. KANAZAWA, Y., KITADA, M., MORI, T., INOKAI, Y., IMAOKA, S., FUNAE, Y. and KAMATAKI, T., 1991, Ascorbic acid deficiency decreased specific forms of cytochrome P-450 in liver microsomes of guinea pigs. Molecular Pharmacology, 39, 456-460.
102. KAPPAS, A., ALVARES, A. P., ANDERSON, K. E., PANTUCK, K. J., PANTUCK, C. B., CHANG, R. and CONNEY, A. H., 1978, Effect of charcoal-broiled beef on antipyrine and theophylline metabolism. Clinical Pharmacology and Therapeutics, 23, 445-450.
103. KAPPAS, A., ANDERSON, K. E., CONNEY, A. H. and ALVARES, A. P., 1976, Influence of dietary protein and carbohydrate on antipyrine and theophylline metabolism in man. Clinical Pharmacology and Therapeutics, 20, 643-653.
104. KATO, R. and GILLETTE, J. R., 1965, Effect of starvation on NADPH-dependent enzymes in liver microsomes of male and female rats. Journal of Pharmacology and Experimental Therapeutics, 150, 279-284.
105. KAWATA, S. TAMURA, S., MATSUDA, Y., ITO, N. and MATSUZAWA, Y., 1992, Effect of dietary fiber on cytochrome P450IA1 in rat colonic mucosa. Carcinogenesis, 13, 2121-2125.
106. KIM, R. B. and WILKINSON, G. R., 1996, Watercress inhibits human CYP2E1 activity in vivo as measured by chlorzoxazone 6-hydroxylation. Clinical Pharmacology and Therapeutics, 59, 170.
107. KLEMAN, K., ÖVERVIK, E., MASON, G. and GUSTAFSSON, J.-Å., 1990, Effects of the food mutagens MEIQx and PhIP on the expression of P4501A proteins in various tissues of male and female rats. Carcinogenesis, 11, 2185-2189.
108. KOJO, A., PELLINEN, P., JUVONEN, R., RAUNIO, H., PELKONEN, O. and PASANEN, M., 1996, Distinct responses of mouse hepatic CYP enzymes to corn oil and peroxisome proliferators. Biochemical Pharmacology, 51, 1137-1143.
109. KOLARS, J. C., SCHMIEDLIN-REN, P., SCHUETZ, J. D., FANG, C. and WATKINS, P. B., 1992, Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. Journal of Clinical Investigation, 90, 1871-1878.
110. KUBOTA, S., LASKER, J. M. and LIEBER, C. S., 1988, Molecular regulation of ethanol-inducible cytochrome P-45-IIE1 in hamsters. Biochemical and Biophysical Research Communications, 150, 304-310.
111. KUENZIG, W., TKACZEVSKI, V., KAMM, J. J., CONNEY, A. H. and BURNS, J. J., 1977, The effects of ascorbic acid deficiency on extrahepatic metabolism of drugs and carcinogens in the guinea pig. Journal of Pharmacology and Experimental Therapeutics, 201, 527-533.
112. KUPFERSCHMIDT, H., HA, H., ZIEGLER, W., MEIER, P. and KRÄHENBÜHL, S., 1995, Interaction between grapefruit juice and midazolam in humans. Clinical Pharmacology and Therapeutics, 58, 20-28.
113. KWAK, M. K., KIM, S. G., KWAK, J. Y., NOVAK, R. F. and KIM, N. D., 1994, Inhibition of cytochrome P4502E1 expression by organosulfur compounds allylsulfide, allylmercaptan and allyl methyl-sulfide in rats. Biochemical Pharmacology, 47, 531-539.
114. LAKE, B. G. and LEWIS, D. F. V., 1996, The CYP4 family. In C. Ioannides (ed.), Cytochromes P450: Metabolic and Toxicological Aspects (Boca Raton: CRC Press), pp. 271-297.
115. LEO, M. A., IIDA, S. and LIEBER, C. S., 1984, Ketinoic acid metabolism by a system reconstituted with cytochrome P-450. Archives of Biochemistry and Biophysics, 234, 305-312.
116. LEO, M. A. and LIEBER, C. S., 1982, Interaction of drugs and retinol. New England Journal of Medicine, 307, 597-601.
117. LEO, M. A. and LIEBER, C. S., 1985, New pathway for retinol metabolism in liver microsomes. Journal of Biological Chemistry, 260, 5228-5231.
118. LEO, M. A., LASKER, J. M., KIM, C.-I., BLACK, M. and LIEBER, C. S., 1989, Metabolism of retinol and retinoic acid by human liver cytochrome P450IIC8. Archives of Biochemistry and Biophysics, 269, 305-312.
119. LEWIS, D. F. V., IOANNIDES, C. and PARKE, D. V., 1986, Molecular dimensions of the substrate binding site of cytochrome P-448. Biochemical Pharmacology, 35, 2179-2185.
120. LI, X.-Y., ÅSTROM, A., DUELL, E. A., QIN, L., GRIFFITHS, C. E. M. and VOORHEES, J. J., 1995, Retinoic acid antagonizes basal as well as coal tar and glucocorticoid-induced cytochrome P5401A1 expression in human skin. Carcinogenesis, 16, 519-524.
121. LOUIS, C. A., WOOD, S. G., KOSTRUBSKY, V., SINCLAIR, P. R. and SINCLAIR, J. F., 1994, Synergistic increases in rat hepatic cytochromes P450 by ethanol and isopentanol. Journal of Pharmacology and Experimental Therapeutics, 269, 838-845.
122. MA, Q., DANNAN, G. A., GUENGERICH, F. P. and YANG, C. S., 1989 Similarities and differences in the regulation of hepatic cytochrome P-450 enzymes by diabetes and fasting in male rats. Biochemical Pharmacology, 38, 3179-3184.
123. MALTZMAN, T. H, CHRISTOU, M., GOULD, M. N. and JEFCOATE, C. R., 1991, Effects of monoterpenoids on in vivo DMBA-DNA adduct formation and on phase I hepatic metabolizing enzymes. Carcinogenesis, 12, 2081-2087.
124. MANJGALADZE, M., CHEN, S., FRAME, L. T., SENG, J. E., DUFFY, P. H., FEUERS, R. J., HART, R. W. and LEAKEY, J. E. A., 1993, Effects of caloric restriction on rodent drug and carcinogen metabolizing-enzymes: implications for mutagenesis and cancer. Mutation Research, 295, 201-222.
125. MANTYLA, E., HIETANEN, E. and AHOTUPA, M., 1982, The effect of dietary cholesterol on monooxygenation and glucuronidation reactions in control and 2,4,5,2′,4′,5′-hexachlorobiphenyl-treated C57BL and DBA/JB mice. In O. Hietanen, M. Laitinen and O. Hanninen (eds), Cytochrome P450, Biochemistry, Biophysics and Environmental Implications (Amsterdam: Elsevier), pp. 161-164.
126. MARTINI, R., BUTLER, A. M., JIANG, X.-M. and MURRAY, M., 1995, Pretranslational down regulation of cytochrome P450 2C11 in vitamin A-deficient male rat liver: prevention by dietary inclusion of retinoic acid. Journal of Pharmacology and Experimental Therapeutics, 273, 427-434.
127. MARTINI, R. and MURRAY, M., 1993, Participation of P450 3A enzymes in rat hepatic microsomal retinoic acid 4-hydroxylation. Archives of Biochemistry and Biophysics, 303, 57-66.
128. MARTINI, R. and MURRAY, M., 1994a, Retinal dehydrogenation and retinoic acid 4-hydroxylation in rat hepatic microsomes: developmental studies and effect of foreign compounds on the activities. Biochemical Pharmacology, 47, 905-909.
129. MARTINI, R. and MURRAY, M., 1994b, Suppression of the constitutive microsomal cytochrome P450 2C11 in male rat liver during dietary vitamin A deficiency. Biochemical Pharmacology, 48, 1305-1309.
130. MAUREL., P., 1996, The CYP3 family. In C. Ioannides (ed.), Cytochromes P450: Metabolic and Toxicological Aspects (Boca Raton: CRC Press), pp. 241-270.
131. MCDANELL, R., MCLEAN, A. E. M., HANLEY, A. B., HEANEY, R. K. and FENWICK, G. R., 1987, Differential induction of mixed-function oxidase (MFO) in rat liver and intestine by diets containing processed cabbage: correlation with cabbage levels of glucosinolates and glucosinolate hydrolysis products. Food and Chemical Toxicology, 25, 363-368.
132. MCDANELL, R., MCLEAN, A. E. M., HANLEY, A. B., HEANEY, R. K. and FENWICK, G. R., 1990, The effect of feeding Brassica vegetables and intact glucosinolates on mixed-function oxidase activity in the livers and intestines of rats. Food and Chemical Toxicology, 27, 289-293.
133. MCDANELL., R. E., HENDERSON, L. A., RUSSELL, K. and MCLEAN, A. E. M., 1992, The effect of Brassica vegetable consumption on caffeine metabolism in humans. Human and Experimental Toxicology, 11, 167-172.
134. MERKEL, U., SIGUSCH, U. and HOFFMANN, A., 1994, Grapefruit juice inhibits 7-hydroxylation of coumarin in healthy volunteers. European Journal of Clinical Pharmacology, 261, 1195-1199.
135. MILLER, K. W. and YANG, C. S., 1984, Studies on the mechanism of induction of N-nitroso-dimethylamine demethylase by fasting, acetone and ethanol. Archives of Biochemistry and Biophysics, 229, 483-491.
136. MILLER, M. S., BRENDEL, K., BURKS, T. F. and SIPES, I. G., 1983, Interactions of capsaicinoids with drug-metabolizing systems. Biochemical Pharmacology, 32, 547-551.
137. MIN, D. I., KU, Y.-M., GERAETS, D. R. and LEE, H.-C., 1996, Effect of grapefruit juice on the pharmacokinetics and pharmacodynamics of quinidine in healthy volunteers. Journal of Clinical Pharmacology, 36, 469-476.
138. MIRANDA, C. L., MUKHTAR, H., BEND, J. R. and CHHABRA, R. S., 1979, Effects of vitamin A deficiency on hepatic and extrahepatic mixed-function oxidase and epoxide-metabolizing enzymes in guinea pig and rabbit. Biochemical Pharmacology, 28, 2713-2716.
139. MORGAN, E. T., MACGEOCH, C. and GUSTAFSSON, J.-Å., 1985, Hormonal and developmental regulation and expression of the hepatic microsomal steroid 16α-hydroxylase cytochrome P-450 apoprotein in the rat. Journal of Biological Chemistry, 260, 11895-11898.
140. MORI, T., ITOH, S., OHGIYA, S., ISHIZAKI, K. and KAMATAKI, T., 1997, Regulation of CYP1A and CYP3A mRNAs by ascorbic acid in guinea pigs. Archives of Biochemistry and Biophysics, 348, 268-277.
141. MORI, T., KITAMURA, R., IMAOKA, S., FUNAE, Y., KITADA, M. and KAMATAKI, T., 1992, Examination for lipid peroxidation in liver microsomes of guinea pigs as causal factor in the decrease in the content of cytochrome P-450 due to ascorbic acid deficiency. Research Communications in Chemical Pathology and Pharmacology, 75, 209-219.
142. MORI, T., KITAMURA, R., IMAOKA, S., FUNAE, Y., MATSUBARA, T. and KAMATAKI, T., 1993, Increased CYP1A2 content and capacity to activate Glu-P-1 and Trp-P-2 in liver microsomes of scorbutic ODS rats. Carcinogenesis, 14, 2471-2475.
143. MURRAY, M., 1991, In vitro and in vivo studies of the effect of vitamin E on microsomal cytochrome P-450 in rat liver. Biochemical Pharmacology, 42, 2107-2114.
144. MURRAY, M., BUTLER, A. M. and AGUS, C., 1996, Restoration of cytochrome P450 2C11 in vitamin A-deficient rat liver by exogenous androgen. FASEB Journal, 10, 1058-1063.
145. MURRAY, M., CANTRILL, E., FROST, L., MEHTA, I. and FARRELL, G. C., 1988, Effects of long-term choline deficiency on hepatic microsomal cytochrome P450-mediated steroid and xenobiotic hydroxylases in the female rat. Biochemical Pharmacology, 37, 1187-1192.
146. MURRAY, M., CANTRILL, R., MARTINI, G. and FARRELL, G., 1991, Increased expression of cytochrome P450IIIA2 in male rat liver after dietary vitamin A supplementation. Archives of Biochemistry and Biophysics, 286, 618-624.
147. UT-A, in hepatic cirrhosis. Molecular Pharmacology, 31, 117-121.
148. NAKAHAMA, T., FUKUHARA, M., OHKUBO, C. and ASANO, M., 1992, Modulation of hepatic and pulmonary drug-metabolizing enzyme activities of rabbits by dietary cholesterol. Research Communications in Chemical Pathology and Pharmacology, 75, 57-68.
149. NANJI, A. A., ZHAO, S., LAMB, R. G., DENNENBERG, A. J., SADRZADEH, S. M. H. and WAXMAN, D. J. (1994) Changes in cytochromes P-450, 2E1, 2B1 and 4A, and phospholipases A and C in the intragastric feeding rat model for alcoholic liver disease: relationship to dietary fats and pathologic liver injury. Alcoholism: Clinical and Experimental Research, 18, 902-908.
150. NIMS, R. W. and LUBET, R. A., 1996, The CYP2B subfamily. In C. Ioannides (ed.), Cytochromes P450: Metabolic and Toxicological Aspects (Boca Raton: CRC Press), pp. 135-160.
151. NORRED, W. P. and WADE, A. E., 1972, Dietary fatty-induced alterations of hepatic microsomal drug metabolism. Biochemical Pharmacology, 21, 2887-2897.
152. OKEY, A. B., 1990, Enzyme induction in the cytochrome P-450 system. Pharmacology and Therapeutics, 45, 241-298.
153. OLSSON, U., LUNDGREN, B., SEGURA-AGUILLAR, J., MESSING-ERILSSON, A., ANDERSSON, K., BECEDAS, L. and DE PIERRE, J. W., 1993, Effects of selenium deficiency on xenobiotic-metabolizing and other enzymes in rat liver. International Journal of Vitamin and Nutrition Research, 63, 31-37.
154. O'SHEA, D., DAVIS, S. N., KIM, R. B. and WILKINSON, G. R., 1994, Effect of fasting and obesity in humans on the 6-hydroxylation of chlorzoxazone: a putative probe of CYP2E1 activity. Clinical Pharmacology and Therapeutics, 56, 359-367.
155. PANTUCK, E. J., HSIAO, K.-C., LOUB, W. D., WATTENBERG, L. W., KUNTZMAN, R. and CONNEY, A. H., 1976, Stimulatory effects of vegetables on intestinal drug metabolism in the rat. Journal of Pharmacology and Experimental Therapeutics, 198, 278-283.
156. PANTUCK, E. J., PANTUCK, E. B., GARLAND, W. A., MIN, B. H., WATTENBERG, L. W., ANDERSON, K. E., KAPPAS, A. and CONNEY, A. H., 1979, Stimulatory effect of Brussel sprouts and cabbage on human drug metabolism. Clinical Pharmacology
157. PARKE, D. V., 1991, Nutritional requirements for detoxication of environmental chemicals. Food Additives and Contaminants, 8, 381-396.
158. PARKE, D. V. and IOANNIDES, C., 1981, The role of nutrition in toxicology. Annual Review of Nutrition, 1, 207-234.
159. PARKE, D. V. and IOANNIDES, C., 1994, The effects of nutrition on chemical toxicity. Drug Metabolism Reviews, 26, 739-765.
160. PASCOE, G. A., SAKAI-WOND, J., SOLIVEN, E. and CORREIA, M. A., 1983, Regulation of intestinal cytochrome P-450 and heme by dietary nutrients. Critical role of selenium. Biochemical Pharmacology, 32, 3027-3035.
161. PELKONEN, O. and SOTANIEMI, E. A., 1987, Environmental factors of enzyme induction and inhibition. Pharmacology and Therapeutics, 33, 115-120.
162. PERIQUET, B., PERIQUET, A., BAILLY, A., GHISOLFI, J. and THOUVENOT, J., 1986, Effects of retinoic acid on hepatic cytochrome P450 dependent enzymes in rats under different vitamin A status. International Journal of Vitamin and Nutrition Research, 56, 223-229.
163. PERROT, N., NALPAS, B., YANG, C. S. and BEAUNE, P. H., 1989, Modulation of cytochrome P450 isozymes in human liver, by ethanol and drug intake. European Journal of Clinical Investigation, 19, 549-555.
164. PESSAYRE, D., DOLDER, A., ARTIGOU, J. Y., WANDSCHEER, J. C., DESCATOIRE, V., DEGOTT, C. and BENHAMOU, J. P., 1979, Effect of fasting on metabolite-mediated hepatotoxicity in the rat. Gastroenterology, 77, 264-271.
165. PETERSON, F. J., HOLLOWAY, D. E., DIQUETTE, P. H. and RIVERS, J. M., 1983, Dietary ascorbic acid and hepatic mixed-function oxidase activity in the guinea pig. Biochemical Pharmacology, 32, 91-96.
166. PEZZUTO, J. M., 1997, Plant-derived anticancer agents. Biochemical Pharmacology, 53, 121-133.
167. PINEAU, T., DAUJAT, M., PICHARD, L., GIRARD, F., ANGEVAIN, J., BONFILS, C. and MAUREL, P., 1991, Developmental expression of rabbit cytochrome P450 CYP1A1, CYP1A2 and CYP3A6 genes. European Journal of Biochemistry, 197, 145-153.
168. PIRMOHAMED, M. and PARK, B. K., 1996, Cytochromes P450 and Immunotoxicity. In C. Ioannides (ed.), Cytochromes P-450: Metabolic and Toxicological Aspects (Boca Raton: CRC Press), pp. 329-354.
169. RAO, G. N. and KNAPKA, J. J., 1998, Animal diets in safety evaluation studies. In C. Ioannides (ed.), Nutrition and Chemical Toxicity (Chichester: John Wiley) (pp. 345-374).
170. RASHID, J., MCKINSTRY, C., RENWICK, A. G., DIRNHUBER, M., WALLER, D. G. and GEORGE, C. F., 1993, Quercetin, an in vitro inhibitor of CYP3A, does not contribute to the interaction between nifedipine and grapefruit juice. British Journal of Clinical Pharmacology, 36, 460-463.
171. RAUCY, J. L., 1995, Risk assessment: toxicity from chemical exposure resulting from enhanced expression of CYP2E1. Toxicology, 105, 217-223.
172. RAUCY, J. L., LASKER, J. M., KRANER, J. C., SALAZAR, D. E., LIEBER, C. S. and CORCORAN, J. B., 1991, Induction of cytochrome P450IIE1 in the obese overfed rat. Molecular Pharmacology, 39, 275-280.
173. RAUCY, J. L., SCHULTZ, E. D., WESTER, M. R., ARORA, S., JOHNSTON, D. E., OMDAHL, J. L. and CARPENTER, S. P., 1997, Human lymphocyte cytochrome P4502E1, a putative marker for alcohol-mediated changes in hepatic chlorzoxazone activity. Drug Metabolism and Disposition, 25, 1429-1435.
174. REICKS, M. M. and CRANKSHAW, D. L., 1996, Modulation of rat hepatic cytochrome P-450 activity by garlic organosulfur compounds. Nutrition and Cancer, 25, 242-248.
175. REKKA, E., AYALOGU, E. A., LEWIS, D. F. V., GIBSON, G. G. and IOANNIDES, C., 1994, Induction of hepatic microsomal CYP4A activity and peroxisomal β-oxidation by two non-steroidal anti-inflammatory drugs. Archives of Toxicology, 68, 73-78.
176. RENDIC, S. and DI CARLO, F. J., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers and inhibitors. Drug Metabolism and Disposition, 29, 413-580.
177. RICHARDSON, T. H. and JOHNSON, E. F., The CYP2C family. In C. Ioannides (ed.), Cytochromes P450: Metabolic and Toxicological Aspects (Boca Raton: CRC Press), pp. 161-181.
178. ROBERTS, A. B., NICHOLS, M. D., NEWTON, D. L. and SPORN, M. B., 1979, In vitro metabolism of retinoic acid in hamster intestine and liver. Journal of Biological Chemistry, 254, 6296-6302.
179. ROBERTS, B. J., SHOAF, S. E., JEONG, K.-S. and SONG, B. J., 1994, Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: evidence that CYP2E1 possesses a rapid phase half-life of 6 hours or less. Biochemical and Biophysical Research Communications, 205, 1064-1071.
180. ROBERTS, B. J., SHOAF, S. E. and SONG, B. J., 1995, Rapid changes in cytochrome P4502E1 (CYP2E1) activity and other P450 isozymes following ethanol withdrawal in rats. Biochemical Pharmacology, 49, 1665-1673.
181. ROBERTS, E. S., VAZ, A. D. N. and COON, M. J., 1992, Role of isozymes of rabbit microsomal cytochrome P-450 in the metabolism of retinoic acid, retinol and retinal. Molecular Pharmacology, 41, 427-433.
182. ROFFEY, S. J., WALKER, R. and GIBSON, G. G., 1990, Hepatic peroxisomal and microsomal enzyme induction by citral and linalool in rats. Food and Chemical Toxicology, 28, 403-408.
183. ROMPELBERG, C. J. M., VERHAGEN, H. and VAN BLADEREN, P. J., 1993, Effects of the naturally occurring alkenylbenzenes eugenol and trans-anethole on drug-metabolizing enzymes in the rat liver. Food and Chemical Toxicology, 31, 637-645.
184. RONIS, M. J. J., LINDROS, K. O. and INGELMAN-SUNDBERG, M., 1996, The CYP2E subfamily. In C. Ioannides (ed.), Cytochromes P450: Metabolic and Toxicological Aspects (Boca Raton: CRC Press), pp. 211-239.
185. RONIS, M. J. J., HUANG, J., LONGO, Y., TINDBERG, N., INGELMAN-SUNDBERG, M. and BADGER, T. M., 1998, Expression and distribution of cytochrome P450 enzymes in male rat kidney: effects of ethanol, acetone and dietary conditions. Biochemical Pharmacology, 55, 123-129.
186. ROOMI, M. W., OGG, M., TSAO, C. S. and GIBSON, G. G., 1997, Ascorbic acid deficiency decreases the expression of CYP4A1 in liver microsomes of guinea pigs. Research Communications in Chemical Pathology and Pharmacology, 95, 3-10.
187. ROSENBERG, D. W., 1991, Dietary modulation of cytochrome P450 in the small intestinal epithelium. Pharmacology, 43, 36-46.
188. RUBIN, E., HUTTERER, F. and LIEBER, C. S., 1968, Ethanol induces hepatic smooth endoplasmic reticulum and drug-metabolising enzymes. Science, 156, 1469-1470.
189. SACHAN, D., 1982, Modulation of drug metabolism by food restriction in male rats. Biochemical and Biophysical Research Communications, 104, 984-989.
190. SACHAN, D. S. and SU, P. K., 1986, Effects of levels of feed restriction on in vivo and in vitro alterations in drug metabolism and associated enzymes. Drug-Nutrient Interactions, 4, 363-370.
191. SENG, J. E., GANDY, J., TURTURRO, A., LIPMAN, R., BRONSON, R. T., PARKINSON, A., JOHNSON, W., HART, R. W. and LEAKEY, J. A., 1996, Effects of caloric restriction on expression of testicular cytochrome P450 enzymes associated with the metabolic activation of chemical carcinogens. Archives of Biochemistry and Biophysics, 335, 42-52.
192. SHERTZER, H. G., 1982, Indole-3-carbinol and indole-3-acetonitrile influence on hepatic microsomal metabolism. Toxicology and Applied Pharmacology, 64, 353-361.
193. SHIMADA, T., GILLAM, E. M. J., SUTTER, T. R., STRICKLAND, P. T., GUENGERICH, F. P. and YAMAZAKI, H., 1997, Oxidation of xenobiotics by recombinant cytochrome P450 1B1. Drug Metabolism and Disposition, 25, 617-622.
194. SINHA, R., ROTHMAN, R., BROWN, E. D., MARK, S. D., HOOVER, R. N., CAPORASO, N. E., LEVANDE, R. O. A., KNIZE, M. G., LANG, N. P. and KADLUBAR, F. F., 1994, Pan-fried meat containing high levels of heterocyclic aromatic amines but low levels of polycyclic aromatic hydrocarbons induces cytochrome P4501A2 activity in humans. Cancer Research, 54, 6154-6159.
195. SKOG, K. I. and JÄGERSTAD, M., 1998, Toxicants in food: Generation during cooking. In C. Ioannides (ed.), Nutrition and Chemical Toxicity (Chichester: John Wiley) (pp. 59-79).
196. SOHN, H. O., LIM, H. B., LEE, Y. G., LEE, D. W. and LEE, K. B., 1994b, Modulation of cytochrome P-450 induction by long-term food restriction in male rats. Biochemistry and Molecular Biology International, 32, 889-896.
197. SOHN, O. S., SURACE, A., FIALA, E. S., RICHIE JR, J. P., COLOSIMO, S., ZANG, E. and WEISBURGER, J. H., 1994a, Effects of green and black tea on hepatic xenobiotic metabolizing systems in male F344 rats. Xenobiotica, 24, 119-127.
198. SONG, B.-J., VEECH, R. L., PARK, S. S., GELBOIN, H. V. and GONZALEZ, F. J., 1989, Induction of rat hepatic N-nitrosodimethylamine demethylase by acetone is due to protein stabilization. Journal of Biological Chemistry, 264, 3568-3572.
199. SOUCEK, P. and GUT, I., 1992, Cytochromes P-450 in rats: structures, functions, properties and relevant human forms. Xenobiotica, 22, 83-103.
200. SPEAR, P. A., GARCIN, H. and NARBONNE, J. F., 1988, Increased retinoic acid metabolism following 3,3′,4,4′,5,5′-hexachlorobiphenyl injection. Canadian Journal of Physiology and Pharmacology, 66, 1181-1186.
201. SPENCE, J. D., 1997, Drug interactions with grapefruit: Whose responsibility is to warn the public? Clinical Pharmacology and Therapeutics, 61, 395-400.
202. STEELE, C. M. and IOANNIDES, C., 1986, Differential effects of chronic ethanol administration to rats on the activation of aromatic amines to mutagens in the Ames test. Carcinogenesis, 7, 825-829.
203. 1 in the rat. Drug Metabolism and Disposition, 22, 383-391.
204. STRESSER, D. M., WILLIAMS, D. E., GRIFFIN, D. A. and BAILEY, G. S., 1995, Mechanism of tumor modulation by indole-3-carbinol: disposition and excretion in male Fischer 344 rats. Drug Metabolism and Disposition, 23, 965-974.
205. STROTHER, S. and CHAU, L. S. K., 1980, Influence of glucose (in vitro or in vivo) on duration of narcotic analgesics and on the kinetics of drug metabolism. Pharmacology, 21, 161-166.
206. STROTHER, A., THROCKMORTON, J. K. and HERZER, C., 1971, The influence of high sugar consumption by mice on the duration of action of barbiturates and the in vitro metabolism of barbiturates, aniline and p-nitroanisole. Journal of Pharmacology and Experimental Therapeutics, 179, 490-498.
207. SUN, B. and FUKUHARA, M., 1997, Effects of co-administration of butylated hydroxytoluene, butylated hydroxyanisole and flavonoids on the activation of mutagens and drug-metabolizing enzymes in mice. Toxicology, 122, 61-72.
208. SURH, Y.-J., LEE, R. C.-J., PARK, K.-K., MAYNE, S. T., LIEM, A. and MILLER, J. A., 1995, Chemo-protective effects of capsaicin and diallyl sulfide against mutagenesis and tumorigenesis by vinyl carbamate and N-nitrosodimethylamine. Carcinogenesis, 16, 2467-2471.
209. SUZUKI, H., TORII, Y., HITOMI, K. and TSUKAGOSHI, N., 1993, Ascorbate-dependent elevation of mRNA levels for cytochrome P450s induced by polychlorinated biphenyls. Biochemical Pharmacology, 46, 186-189.
210. TAKAHASHI, H., JOHANSSON, I., FRENCH, S. W. and INGELMAN-SUNDBERG, M., 1992, Effects of dietary fat composition on activities of the microsomal ethanol oxidizing system and ethanol-inducible cytochrome P450 (CYP2E1) in the liver of rats chronically fed ethanol. Pharmacology and Toxicology, 70, 347-352.
211. TANNENBAUM, G. S., RORSTAD, O. and BRAZEAU, B., 1979, Effects of prolonged food deprivation on the ultradian growth hormone rhythm and immunoreactive somatostatin tissue levels in the rat. Endocrinology, 104, 1733-1738.
212. TASSANEEYAKUL, W., BIRKETT, D. J., VERONESE, M. E., MCMANUS, M. E., TUKEY, R. H., QUATROCHI, L. C., GELBOIN, H. V. and MINERS, J. O., 1993, Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2. Journal of Pharmacology and Experimental Therapeutics, 265, 401-407.
213. UENG, T.-H., UENG, Y.-F., CHEN, T.-L., PARK, S. S., IWASAKI, M. and GUENGERICH, F. P., 1993a, Induction of cytochrome P450-dependent monooxygenases in hamster tissues by fasting. Toxicology and Applied Pharmacology, 119, 66-73.
214. UENG, T.-H., UENG, Y.-F., TSAI, J. N., CHAO, I.-C., CHEN, T.-L., PARK, S. S., IWASAKI, M. and GUENGERICH, F. P., 1993b, Induction and inhibition of cytochrome P-450 dependent monooxygenases in hamster tissues by ethanol. Toxicology, 81, 145-154.
215. USHIO, F., FUKUHARA, M., BANI, M.-H. and NARBONNE, J.-F., 1996, Expression of cytochrome P450 isozymes in Syrian hamster after vitamin A supplementation and deficiency. International Journal for Vitamin and Nutrition Research, 66, 197-202.
216. VANG, O., JENSEN, M. B. and AUTRUP, H., 1991, Induction of cytochrome P-450IA1, IA2, IIB1 and IIE1 by broccoli in rat liver and colon. Chemico-Biological Interactions, 78, 85-96.
217. VERMEULEN, N. P. E., 1996, Role of metabolism in chemical toxicity. In C. Ioannides (ed.), Cytochromes P450: Metabolic and Toxicological Aspects (Boca Raton: CRC Press), pp. 29-53.
218. VISTISEN, K., POULSEN, H. E. and LOFT, S., 1992, Foreign compound metabolism capacity in man measured from metabolites of dietary caffeine. Carcinogenesis, 13, 1561-1568.
219. WADE, A. E. and EVANS, J. S., 1977, Influence of norethindroneon drug-metabolizing enzymes of female rat liver in various B-vitamin deficiency states. Pharmacology, 15, 289-301.
220. WADE, A. E., WHITE, R. A., WALTON, L. C. and BELLOWS, J. T., 1985, Dietary fat - a requirement for induction of mixed-function oxidase activities in starved-refed rats. Biochemical Pharmacology, 34, 3747-3754.
221. WATTENBERG, L. W., 1993, Chemoprevention of carcinogenesis by minor non-nutrient constituents of the diet. In D. V. Parke, C. Ioannides and R. Walker (eds), Food, Nutrition and Chemical Toxicity (London: Smith-Gordon Nishimura) pp. 287-300.
222. WESTIN, S., MODE, A., MURRAY, M., CHEN, R. and GUSTAFSSON, J.-Å., 1993, Growth hormone and vitamin A induce P450 2C7 mRNA expression in primary rat hepatocytes. Molecular Pharmacology, 44, 997-1002.
223. WORTELBOER, H. M., DE KRUIF, C. A., VAN ISRAE, L. A. J. J., NOORDHOEK, J., BLAAUBOER, B. J., VAN BLADEREN, P. J. and FALKE, H. E., 1992a, Effects of cooked Brussels sprouts on cytochrome P-450 profile and phase-II enzymes in liver and small intestinal mucosa of the rat. Food and Chemical Toxicology, 30, 17-27.
224. WORTELBOER, H. M., VAN DER LINDEN, E. C. M., DE KRUIF, C. A., NOORDHOEK, J., BLAAUBOER, B. J., VAN BLADEREN, P. J. and FALKE, H. E., 1992b, Effects of indole-3-carbinol on biotransformation enzymes in the rat: in vivo changes in liver and small intestinal mucosa in comparison with primary hepatocyte cultures. Food and Chemical Toxicology, 30, 589-599.
225. WRIGHT, M. C., ALLENBY, G. and PAINE, A. J., 1997, Effect of vitamin A deficiency on the expression of low affinity glucocorticoid binding site activity and glucocorticoid-dependent induction of CYP3A2 in rat liver. Biochemical Biophysical Research Communications, 237, 211-216.
226. WRIGHTON, S. A. and ELSWICK, B., 1989, Modulation of the induction of rat hepatic cytochromes P450 by selenium deficiency. Biochemical Pharmacology, 38, 3767-3771.
227. XU, Z. and BRAY, T. M., 1992, Effects of increased microsomal oxygen radicals on the function and stability of cytochrome P450 in dietary zinc deficient rats. Journal of Nutritional Biochemistry, 3, 326-332.
228. YAMADA, H., FUJISAKI, H., KANEKO, H., ISHII, Y., HAGAMUCHI, T. and OGURI, K., 1993, Picrotoxin as a potent inducer of rat hepatic cytochrome P450, CYP2B1 and CYP2B2. Biochemical Pharmacology, 45, 1783-1789.
229. YANG, C. S., BRADY, J. F. and HONG, J.-Y., 1992, Dietary effects on cytochromes P450, xenobiotic metabolism and toxicity. FASEB Journal, 6, 737-744.
230. YANG, C. S. and WANG, Z. Y., 1993, Tea and cancer. Journal of the National Cancer Institute, 85, 1038-1049.
231. YANG, C. S. and YOO, J.-S. H., 1988, Dietary effects on drug metabolism by the mixed-function oxidase system. Pharmacology and Therapeutics, 38, 53-72.
232. YEE, G. D., STANLEY, D. L., PESSA, L., DALLA COSTA, T., BELTZ, S. E., RUIZ, J. and LOWENTHAL, D. T., 1995, Effect of grapefruit juice on blood cyclosporin concentration. Lancet, 345, 955-956.
233. YOO, J.-S. H., HONG, J.-Y., NING, S. M. and YANG, C. S., 1990a, Roles of dietary corn oil in the regulation of cytochromes P450 and glutathione S-transferases in the rat liver. Journal of Nutrition, 120, 1718-1726.
234. YOO, J.-S. H., PARKM, H.-S., NING, S. M., LEE, M.-J. and YANG, C. S., 1990b, Effect of thiamine deficiency on hepatic cytochromes P450 and drug metabolizing enzyme activities. Biochemical Pharmacology, 39, 519-525.
235. Yoo, J.-S. H., MING, S. M., PANTUCK, C. B., PANTUCK, E. J. and YANG, C. S., 1991, Regulation of hepatic microsomal cytochrome P450IIK1 level by dietary lipids and carbohydrates in rats. Journal of Nutrition, 121, 959-965.
236. YOO, J.-S. H., SMITH, T. J., MING, S. M., LEE, M.-J., THOMAS, P. E. and YANG, C. S., 1992, Modulation of the levels of cytochromes P450 in rat liver and lung by dietary lipid. Biochemical Pharmacology, 43, 2535-2542.
237. YUN, Y.-P., CASAZZA, J. P., SOHN, D. H., VEECH, R. L. and SONG, B. J., 1992, Pretranslational activation of cytochrome P450IIE during ketosis induced by a high fat diet. Molecular Pharmacology, 41, 474-479.
238. ZHANG, J., HENNING, S. M., HEBER, D., CHOI, J., WANG, Y., SWENDSEID, M. E. and GO, V. L. W., 1997, NADPH-Cytochrome P-450 reductase, cytochrome P-450 2C11 and P-450 1A1, and the aryl hydrocarbon receptor in livers of rats fed methyl-folate-deficient diets. Nutrition and Cancer, 28, 160-164.