CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane

Carcinogenesis

Volumn 17, Issue 2, 1996, Pages 277-282

  Barcelo, Silvia ^a,b   Gardiner, John M ^c   Gescher, Andreas ^d   Chipman, J Kevin ^b  

^a ASTON UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROPHENOL; 7,12 DIMETHYLBENZ[A]ANTHRACENE; ACETONE; CYTOCHROME P450 ISOENZYME; DIMETHYLNITROSAMINE; NITROSAMINE; PLANT EXTRACT; SODIUM AZIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; COMPETITIVE INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DETOXIFICATION; DOSE RESPONSE; ENZYME INHIBITION; GENOTOXICITY; HYDROXYLATION; LIVER MICROSOME; MALE; MOUSE; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SALMONELLA TYPHIMURIUM; UNSCHEDULED DNA SYNTHESIS;

ANIMALS; ANTICARCINOGENIC AGENTS; AZIDES; BIOTRANSFORMATION; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; DNA; DNA REPAIR; ISOTHIOCYANATES; MALE; MICE; MICE, INBRED BALB C; MIXED FUNCTION OXYGENASES; MUTAGENICITY TESTS; NITROSO COMPOUNDS; OXIDOREDUCTASES, N-DEMETHYLATING; RATS; RATS, SPRAGUE-DAWLEY; SALMONELLA TYPHIMURIUM; SODIUM AZIDE; THIOCYANATES;

EID: 0029879994     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.2.277     Document Type: Article

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