Induction of rat hepatic cytochrome P4501A and P4502B by the methoxsalen

Cancer Letters

Volumn 109, Issue 1-2, 1996, Pages 115-120

  Gwang, Jeong Hye ^a  

^a Chosun University   (South Korea)

Author keywords

Biphasic response; Cytochrome P450; Induction; Methoxsalen

Indexed keywords

CYTOCHROME P450 ISOENZYME; ENZYME ANTIBODY; ETHOXYRESORUFIN DEETHYLASE; LIVER ENZYME; MESSENGER RNA; METHOXSALEN; MICROSOME ENZYME;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INDUCTION; GENE INDUCTION; IMMUNOBLOTTING; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER METABOLISM; MALE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT;

EID: 0030568081     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(97)82727-9     Document Type: Article

References (30)

1. [1] Parrish, J.A., Fitzpatrick, T.B., Tanenbaum, L. and Pathak, M.A. (1974) Photochemotharapy of psoriasis with oral methoxsalen and longwave ultraviolet light, N. Engl. J. Med., 291, 1207-1211.
2. [2] Scott, B.R., Pathak, M.A. and Mohn, G.R. (1976) Molecular and genetic basis of furocoumarin reactions, Mutat. Res., 39, 29-74.
3. [3] Anderson, T.F. and Voorhees, J.J. (1980) Psoralen photochemotherapy of cutaneous disorders, Annu. Rev. Pharmacol. Toxicol., 20, 235-257.
4. [4] Song, P.S. and Tapley Jr., K.J. (1979) Photochemistry and photobiology of psoralens, Photochem. Photobiol., 29, 1177-1197.
5. [5] Edelson, R., Berger, C., Gasparro, F., Jegasothy, B., Heald, P., Wintroub, B., Vonderheid, E., Knobler, R., Wolff, K., Plewig, G., McKiernan, G., Christiansen, I., Oster, M., Honigsmann, H., Wilford, H., Kokoschka, E., Rehle, T., Perez, M., Stingl, G. and Laroche, L. (1987) Treatment of cutaneous T-cell lymphoma by extracorporeal photochemotherapy, N. Engl. J. Med., 316, 297-303.
6. [6] Gonzalez, F.J. (1989) The molecular biology of cytochrome P450s, Pharmacol. Rev., 40, 243-288.
7. [7] Labbe, G., Descatorie, V., Letteron, P., Tinel, M., Larrey, D., Carrion-Pavlov, Y., Geneve, J., Amouyal, G. and Pessayre, D. (1987) The drug methoxsalen, a suicide substrate for cytochrome P-450, decreases the metabolic activation, and prevents the hepatotoxicity, of carbon tetrachloride in mice, Biochem. Pharmacol., 36, 907-914.
8. [8] Tinel, M., Belghiti, J., Descatoire, V., Amouyal, G., Letteron, P., Geneve, J., Larrey, D. and Pressayre, D. (1987) Inactivation of human liver cytochrome P-450 by the drug methoxsalen and other psoralen derivatives, Biochem. Pharmacol., 36, 951-955.
9. [9] Fouin-Fortunet, H., Tinel, M., Descatoire, V., Letteron, P., Larrey, D., Geneve, J. and Pessayre, D. (1986) Inactivation of cytochrome P-450 by the drug methoxsalen, J. Pharmacol. Exp. Ther., 236, 237-247.
10. [10] Mays, D.C., Camisa, C., Cheney, P., Pacula, C.M., Nawoot, S. and Gerber, N. (1987) Methoxsalen is a potent inhibitor of the metabolism of caffeine in humans, Clin. Pharmacol. Ther., 42, 621-626.
11. [11] Mays, D.C., Rogers, S.L., Guiler, R.C., Sharp, D.E., Hecht, S.G., Staubus, A.E. and Gerber, N. (1986) Disposition of 8-methoxypsoralen in the rat: methodology for measurement, dose-dependent pharmacokinetics, tissue distribution and identification of metabolites, J. Pharmacol. Exp. Ther., 236, 364-373.
12. [12] Buening, M.K. and Franklin, M.R. (1976) SKF 525A inhibition, induction and 452 nm complex formation, Drug Metab. Dispos., 4, 244-256.
13. [13] Ioannides, C., Delaforge, M. and Parke, D.V. (1981) Safrole: its metabolism, carcinogenicity and interactions with cytochrome P-450, Food Cosmet. Toxicol., 19, 657-663.
14. [14] Phillison, C.E., Godden, P.M.M., Ioannides, C. and Parke, D.V. (1982) The mutagenicity of 9-hydroxyellipticine and its induction of cytochrome P-448 in rat liver microsomes, Carcinogenesis, 3, 1179-1182.
15. [15] Ioannides, C., Delaforge, M. and Parke, D.V. (1985) Interaction of safrole and isosafrole and their metabolites with cytochrome P450, Chem.-Biol. Interactions, 53, 303-311.
16. [16] Rodrigues, A.D., Waddell, P.R., Ah-Sing, E., Morries, B.A., Wolf, C.R. and Ioannides, C. (1988) Induction of the rat hepatic microsomal mixed function oxidases by 3-imidazole-containing anti-fungal agents: selectivity for the cytochrome P450IIB and III families of cytochromes P450, Toxicology, 50, 283-301.
17. [17] Omiecinskik, C.J., Walz, Jr., F.G. and Valasuk, G.P. (1985) Phenobarbital induction of rat liver cytochromes P-450b and P-450e: quantification of specific RNAs by hybridization to synthetic oligodeoxyribonucleotide probes. J. Biol. Chem., 260, 3247-3250.
18. [18] Jeong, H.G., Yun, C.-H., Jeon, Y.J., Lee, S.S. and Yang, K.H. (1995) Suppression of cytochrome P450 Cyp1a-1 induction in mouse hepatoma Hepa-1c1c7 cells by methoxsalen, Biochem. Biophys. Res. Commun., 208, 1124-1130.
19. [19] Omura, T. and Sato, R. (1964) The carbon monoxide binding pigment of liver microsomes, II: solubilization, purification and properties, J. Biol. Chem., 239, 2379-2386.
20. [20] Bruke, M.D., Thompson, S., Elcombe, C.R., Halpert, J., Haaparanta, T. and Mayer, R.T. (1985) Ethoxy-, pentoxy-and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P450, Biochem. Pharmacol., 34, 3337-3345.
21. [21] Mieyal, J.J. and Blumer, J.L. (1976) Acceleration of the auto-oxidation of human oxyhemoglobin by aniline and its relation to hemoglobin-catalyzed aniline hydroxylation, J. Biol. Chem., 251, 3442-3446.
22. [22] Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantitative of protein utilizing the principle of protein-dye binding, Anal. Biochem., 72, 248-254.
23. [23] Guengerich, F.P., Dannan, G.A., Wright, S.T., Martin, M.V. and Kaminsky, L.S. (1982) Purification and characterization of liver microsomal cytochrome P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated phenobarbital or beta-naphtoflavone, Biochemistry, 21, 6019-6030.
24. [24] Jeong, H.G. and Yun, C.H. (1995) Induction of rat hepatic cytochrome P450 enzymes by myristicin, Biochem. Biophys. Res. Commun., 217, 966-971.
25. [25] Laemmli, U.K. (1970) Cleavage of structural protein during the assembly of the head of bacteriophage T4, Nature, 227, 680-685.
26. [26] Chomcztnski, P. and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction, Anal. Biochem., 162, 156-159.
27. [27] Nemoto, N. and Sakurai, J. (1992) Altered regulation of Cyp1a-1 gene expression during cultivation of mouse hepatocytes in primary culture, Biochem. Pharmacol., 44, 51-58.
28. [28] Hecht, S., Climie, J.C., Guiler, R.C., Sharp, D.E., Mats, D.C. and Gerber, N. (1985) Demonstration of inducible metabolism of 8-methoxypsoralen in rat liver microsomes and evidence for covalent binding to microsomal proteins, Fed. Proc., 44, 1467.
29. [29] Bickers, D.R., Mukhtar, H., Molica, Jr., S.J. and Pathak, M.A. (1982) The effect of psoralens on hepatic and cutaneous drug metabolizing enzymes and cytochrome P-450. J. Invest. Dermatol., 79, 201-205.
30. [30] Porter, T.D. and Coon, M.J. (1991) Cytochrome P-450. multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms, J. Biol. Chem., 268, 13469-13472.