메뉴 건너뛰기




Volumn 114, Issue 1, 1996, Pages 19-27

Comparative effects of flavonoids and model inducers on drug-metabolizing enzymes in rat liver

Author keywords

Cytochrome; Flavonoids; Induction; P 450; Transferases

Indexed keywords

3 METHYLCHOLANTHRENE; ACETONE; CIPROFIBRATE; CYTOCHROME B5 REDUCTASE; CYTOCHROME P450; DEXAMETHASONE; FLAVANONE; FLAVONE; FLAVONOID; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; ISOENZYME; PHENOBARBITAL; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; TANGERETIN;

EID: 0030589078     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(96)03412-9     Document Type: Article
Times cited : (110)

References (39)
  • 1
    • 0022390494 scopus 로고
    • Effects of ellipticine, flavone, 7,8-benzoflavone upon 7,12-dimethylbenz[a,h]anthracene initiated skin tumors in mice
    • Alworth, W.L. and Slaga, T.J. (1985) Effects of ellipticine, flavone, 7,8-benzoflavone upon 7,12-dimethylbenz[a,h]anthracene initiated skin tumors in mice. Carcinogenesis 6, 487-493.
    • (1985) Carcinogenesis , vol.6 , pp. 487-493
    • Alworth, W.L.1    Slaga, T.J.2
  • 3
    • 0017597227 scopus 로고
    • Comparison of β-naphthoflavone and 3-methylcholanthrene as inducers of hepatic cytochrome(s) P-448 and AHH hydrocarbon (benzo[a]pyrene) hydroxylase activity
    • Boobis, A.R., Nebert, D.W. and Felton, J.S. (1977) Comparison of β-naphthoflavone and 3-methylcholanthrene as inducers of hepatic cytochrome(s) P-448 and AHH hydrocarbon (benzo[a]pyrene) hydroxylase activity. Mol. Pharmacol. 13, 259-268.
    • (1977) Mol. Pharmacol. , vol.13 , pp. 259-268
    • Boobis, A.R.1    Nebert, D.W.2    Felton, J.S.3
  • 4
    • 0019364430 scopus 로고
    • Activation and inhibition of benzo[a]pyrene and aflatoxin B1 metabolism in human liver microsomes by naturally occurring flavonoids
    • Buening, M.K., Chang, R.L., Huang, M.T., Fortner, J.G., Wood, A.W. and Conney, A.H. (1981) Activation and inhibition of benzo[a]pyrene and aflatoxin B1 metabolism in human liver microsomes by naturally occurring flavonoids. Cancer Res. 41, 67-72.
    • (1981) Cancer Res. , vol.41 , pp. 67-72
    • Buening, M.K.1    Chang, R.L.2    Huang, M.T.3    Fortner, J.G.4    Wood, A.W.5    Conney, A.H.6
  • 5
    • 0022357068 scopus 로고
    • Ethoxy-, pentoxy-, and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between different induced cytochromes P450
    • Burke, M.D., Thompson, S., Elcombe, C.R., Halpert, J., Haaparanta, T. and Mayer, R.T. (1985) Ethoxy-, pentoxy-, and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P450. Biochem. Pharmacol. 34, 3337-3345.
    • (1985) Biochem. Pharmacol. , vol.34 , pp. 3337-3345
    • Burke, M.D.1    Thompson, S.2    Elcombe, C.R.3    Halpert, J.4    Haaparanta, T.5    Mayer, R.T.6
  • 7
    • 0027480793 scopus 로고
    • Evidence for tangeretin O-demethylation by rat and human liver microsomes
    • Canivenc-Lavier, M.C., Brunold, C., Siess, M.H. and Suschetet, M. (1993) Evidence for tangeretin O-demethylation by rat and human liver microsomes. Xenobiotica 23, 259-266.
    • (1993) Xenobiotica , vol.23 , pp. 259-266
    • Canivenc-Lavier, M.C.1    Brunold, C.2    Siess, M.H.3    Suschetet, M.4
  • 8
    • 0015327482 scopus 로고
    • Induction of benzpyrene hydroxylase by flavone and its derivatives in fetal rat liver explants
    • Cutroneo, K.R., Seibert, R.A. and Bresnick, E. (1972) Induction of benzpyrene hydroxylase by flavone and its derivatives in fetal rat liver explants. Biochem. Pharmacol. 21, 937-945.
    • (1972) Biochem. Pharmacol. , vol.21 , pp. 937-945
    • Cutroneo, K.R.1    Seibert, R.A.2    Bresnick, E.3
  • 9
    • 0023113476 scopus 로고
    • Inhibition of epidermal xenobiotic metabolism in SENCAR mice by naturally occurring plant phenols
    • Das, M., Mukhtar, H., Bik, D.P. and Bickers, D.R. (1987) Inhibition of epidermal xenobiotic metabolism in SENCAR mice by naturally occurring plant phenols. Cancer Res. 47, 760-766.
    • (1987) Cancer Res. , vol.47 , pp. 760-766
    • Das, M.1    Mukhtar, H.2    Bik, D.P.3    Bickers, D.R.4
  • 10
    • 0020028678 scopus 로고
    • Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis
    • Guengerich, F.P., Wang, P. and Davidson, N.K. (1982) Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Biochemistry 21, 1698-1706.
    • (1982) Biochemistry , vol.21 , pp. 1698-1706
    • Guengerich, F.P.1    Wang, P.2    Davidson, N.K.3
  • 11
    • 0001680211 scopus 로고
    • Cytochrome P450 enzymes. They defend the body against environmental pollutants, detoxify drugs and synthetize several important signaling molecules
    • Guengerich, F.P. (1993) Cytochrome P450 enzymes. They defend the body against environmental pollutants, detoxify drugs and synthetize several important signaling molecules. Am. Sci. 81, 440-447.
    • (1993) Am. Sci. , vol.81 , pp. 440-447
    • Guengerich, F.P.1
  • 12
    • 0028281363 scopus 로고
    • Modification of hepatic drug-metabolizing enzymes in rats fed naturally occurring allyl sulfides
    • Haber, D., Siess, M.H., De Waziers, I., Beaune, P. and Suschetet, M, (1994) Modification of hepatic drug-metabolizing enzymes in rats fed naturally occurring allyl sulfides. Xenobiotica 24, 169-182.
    • (1994) Xenobiotica , vol.24 , pp. 169-182
    • Haber, D.1    Siess, M.H.2    De Waziers, I.3    Beaune, P.4    Suschetet, M.5
  • 13
    • 0016275313 scopus 로고
    • Glutathione S-transferases. The first enzymatic step in mercapturic acid formation
    • Habig, W.H., Pabst, M.J. and Jakoby, W.B. (1974) Glutathione S-transferases. The first enzymatic step in mercapturic acid formation, J. Biol. Chem. 249, 7130-7139.
    • (1974) J. Biol. Chem. , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 14
    • 0020626421 scopus 로고
    • Commentary: Flavonoids, a class of natural products of high pharmacological potency
    • Havsteen, B., (1983) Commentary: flavonoids, a class of natural products of high pharmacological potency. Biochem. Pharmacol. 32, 1141-1148.
    • (1983) Biochem. Pharmacol. , vol.32 , pp. 1141-1148
    • Havsteen, B.1
  • 15
    • 0026443919 scopus 로고
    • Anticlastogenic effects of flavonoids against mutagen-induced micronuclei in mice
    • Heo, M.Y., Yu, K.S., Kim, K.H., Kim, K.P. and Au, W.W. (1992) Anticlastogenic effects of flavonoids against mutagen-induced micronuclei in mice. Mutat. Res. 284, 243-249.
    • (1992) Mutat. Res. , vol.284 , pp. 243-249
    • Heo, M.Y.1    Yu, K.S.2    Kim, K.H.3    Kim, K.P.4    Au, W.W.5
  • 16
    • 0021052055 scopus 로고
    • Inhibition of the mutagenicity of bay-region diol-epoxides polycyclic aromatic hydrocarbons by phenolic plant flavonoids
    • Huang, M.T., Wood, A.W., Newmark, H.L., Sayer, J.M., Yagi, H, Jerina, D.M. and Conney, A.H. (1983) Inhibition of the mutagenicity of bay-region diol-epoxides polycyclic aromatic hydrocarbons by phenolic plant flavonoids. Carcinogenesis 4, 1631-1637.
    • (1983) Carcinogenesis , vol.4 , pp. 1631-1637
    • Huang, M.T.1    Wood, A.W.2    Newmark, H.L.3    Sayer, J.M.4    Yagi, H.5    Jerina, D.M.6    Conney, A.H.7
  • 17
    • 0026695822 scopus 로고
    • Enhancement of antioxidant and phase II enzymes by oral feeding green tea polyphenols in drinking water to SKH-1 hairless mice: Possible role in cancer chemoprevention
    • Khan, S.G., Katiyar, S.K., Argawal, R. and Mukhtar, H. (1992) Enhancement of antioxidant and phase II enzymes by oral feeding green tea polyphenols in drinking water to SKH-1 Hairless mice: possible role in cancer chemoprevention. Cancer Res. 52, 4050-4052.
    • (1992) Cancer Res. , vol.52 , pp. 4050-4052
    • Khan, S.G.1    Katiyar, S.K.2    Argawal, R.3    Mukhtar, H.4
  • 18
    • 0016906546 scopus 로고
    • The flavonoids. A class of semi-essential food components: Their role in human nutrition
    • Kühnau, J. (1976) The flavonoids. A class of semi-essential food components: their role in human nutrition. World Rev. Nutr. Diet 24, 117-191.
    • (1976) World Rev. Nutr. Diet , vol.24 , pp. 117-191
    • Kühnau, J.1
  • 19
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 20
    • 0021255106 scopus 로고
    • In vitro and in vivo activation of oxidative drug metabolism by flavonoids
    • Lasker, JM., Huang, M.T. and Conney, A.H. (1984) In vitro and in vivo activation of oxidative drug metabolism by flavonoids. J. Pharmacol. Exp. Ther. 229, 162-170.
    • (1984) J. Pharmacol. Exp. Ther. , vol.229 , pp. 162-170
    • Lasker, J.M.1    Huang, M.T.2    Conney, A.H.3
  • 21
    • 0026710778 scopus 로고
    • Inhibition of microsome-mediated binding of benzo[a]pyrene to DNA by flavonoids either in vitro or after dietary administration to rats
    • Le Bon, A.M., Siess, M.H. and Suschetet, M. (1992) Inhibition of microsome-mediated binding of benzo[a]pyrene to DNA by flavonoids either in vitro or after dietary administration to rats. Chem.-Biol. Interact. 83, 65-71.
    • (1992) Chem.-Biol. Interact. , vol.83 , pp. 65-71
    • Le Bon, A.M.1    Siess, M.H.2    Suschetet, M.3
  • 23
    • 0028301966 scopus 로고
    • Hepatoprotective mechanism of silymarin: No evidence for involvement of cytochrome P4502E1
    • Miguez, M.P., Anundi, I., Sainz-Pardo, L.A., Lindros, K.O. (1994) Hepatoprotective mechanism of silymarin: no evidence for involvement of cytochrome P4502E1. Chem.-Biol. Interact. 91, 51-63.
    • (1994) Chem.-Biol. Interact. , vol.91 , pp. 51-63
    • Miguez, M.P.1    Anundi, I.2    Sainz-Pardo, L.A.3    Lindros, K.O.4
  • 24
    • 0016772483 scopus 로고
    • +-linked assay for microsomal undine diphosphate glucuronyltransferase of rat liver and some observations on substrate specificity of the enzyme
    • +-linked assay for microsomal undine diphosphate glucuronyltransferase of rat liver and some observations on substrate specificity of the enzyme, Biochem. J. 151, 131-140.
    • (1975) Biochem. J. , vol.151 , pp. 131-140
    • Mulder, G.J.1    Van Doom, A.B.D.2
  • 25
    • 77049138167 scopus 로고
    • The colorimetric estimation of formaldehyde by means of the Hantzsch reaction
    • Nash, T. (1953) The colorimetric estimation of formaldehyde by means of the Hantzsch reaction. Biochem. J. 55, 416-421.
    • (1953) Biochem. J. , vol.55 , pp. 416-421
    • Nash, T.1
  • 26
    • 0027433751 scopus 로고
    • Induction of rat hepatic and intestinal glutathione S-transferases and glutathione by dietary naturally occurring anticarcinogens
    • Nijhoff, W.A., Groen, G.M. and Peters, W.H.M. (1993) Induction of rat hepatic and intestinal glutathione S-transferases and glutathione by dietary naturally occurring anticarcinogens, Int. J. Oncol. 3, 1131-1139.
    • (1993) Int. J. Oncol. , vol.3 , pp. 1131-1139
    • Nijhoff, W.A.1    Groen, G.M.2    Peters, W.H.M.3
  • 28
    • 78651165715 scopus 로고
    • The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
    • Omura, T. and Sato, R. (1964) The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J. Biol. Chem. 239, 2370-2379.
    • (1964) J. Biol. Chem. , vol.239 , pp. 2370-2379
    • Omura, T.1    Sato, R.2
  • 29
    • 73849173955 scopus 로고
    • Hepatic triphosphopyridine nucleotide-cytochrome c reductase: Isolation, characterization and kinetics studies
    • Phillips, A.H. and Langdon, R.G. (1962) Hepatic triphosphopyridine nucleotide-cytochrome c reductase: isolation, characterization and kinetics studies. J. Biol. Chem. 237, 2652-2660.
    • (1962) J. Biol. Chem. , vol.237 , pp. 2652-2660
    • Phillips, A.H.1    Langdon, R.G.2
  • 30
    • 0018131780 scopus 로고
    • A microsomal (cytochrome P-450)-linked lauric-acid-monooxygenase from aged Jerusalem-artichoke-tuber tissues
    • Salaün, J.P., Benveniste, I., Reichhart, D. and Durst, F. (1978) A microsomal (cytochrome P-450)-linked lauric-acid-monooxygenase from aged Jerusalem-artichoke-tuber tissues. Eur. J. Biochem. 90, 155-159.
    • (1978) Eur. J. Biochem. , vol.90 , pp. 155-159
    • Salaün, J.P.1    Benveniste, I.2    Reichhart, D.3    Durst, F.4
  • 31
    • 0024789913 scopus 로고
    • Induction of monooxygenase and transferase activities in rat by dietary administration of flavonoids
    • Siess, M.H., Guillermic, M., Le Bon, A.M. and Suschetet, M. (1989) Induction of monooxygenase and transferase activities in rat by dietary administration of flavonoids. Xenobiotica 19, 1379-1386.
    • (1989) Xenobiotica , vol.19 , pp. 1379-1386
    • Siess, M.H.1    Guillermic, M.2    Le Bon, A.M.3    Suschetet, M.4
  • 34
    • 0344915418 scopus 로고
    • Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis
    • Talalay, P., De Long, M.J. and Prochaska, H.J. (1988) Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis. Proc. Natl. Acad. Sci. USA 85, 8261-8265.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8261-8265
    • Talalay, P.1    De Long, M.J.2    Prochaska, H.J.3
  • 35
    • 0022656443 scopus 로고
    • Kinetic constant determination of liver microsomal and purified UDP-glucuronosyltransferase after phenobarbital and 3-methylcholanthrene treatments in rats
    • Thomassin, J., Dragacci, S., Faye, B., Magdalou, J. and Siest, G. (1986) Kinetic constant determination of liver microsomal and purified UDP-glucuronosyltransferase after phenobarbital and 3-methylcholanthrene treatments in rats. Comp. Biochem. Physiol. 83, 127-131.
    • (1986) Comp. Biochem. Physiol. , vol.83 , pp. 127-131
    • Thomassin, J.1    Dragacci, S.2    Faye, B.3    Magdalou, J.4    Siest, G.5
  • 37
    • 0014290323 scopus 로고
    • Induction of increased benzpyrene hydroxylase activity by flavones and related compounds
    • Wattenberg, L.W., Page, M.A. and Leong, J.L. (1968) Induction of increased benzpyrene hydroxylase activity by flavones and related compounds. Cancer Res. 28, 934-937.
    • (1968) Cancer Res. , vol.28 , pp. 934-937
    • Wattenberg, L.W.1    Page, M.A.2    Leong, J.L.3
  • 38
    • 0020587373 scopus 로고
    • Inhibition of neoplasia by minor dietary constituents
    • Wattenberg, L.W. (1983) Inhibition of neoplasia by minor dietary constituents. Cancer Res. 43, 24481s-2453s.
    • (1983) Cancer Res. , vol.43
    • Wattenberg, L.W.1
  • 39
    • 0023263168 scopus 로고
    • Nature of N-nitrosodimethylamine demethylase and its inhibitors
    • Yoo, J.S.H., Cheung, R.J., Patten, C.J., Wade, D. and Yang, C.S. (1987) Nature of N-nitrosodimethylamine demethylase and its inhibitors. Cancer Res. 47, 3378-3383.
    • (1987) Cancer Res. , vol.47 , pp. 3378-3383
    • Yoo, J.S.H.1    Cheung, R.J.2    Patten, C.J.3    Wade, D.4    Yang, C.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.