O6-methylguanine-DNA methyltransferase (MGMT) transfectants of a 1,3- bis(2-chloroethyl)-1-nitrosourea (BCNU)-sensitive colon cancer cell line selectively repopulate heterogeneous MGMT+/MGMT- xenografts after BCNU and O6-benzylguanine plus BCNU

Cancer Research

Volumn 57, Issue 21, 1997, Pages 4817-4823

  Phillips Jr , Weldon P ^a   Willson, James K V ^a   Markowitz, Sanford D ^a   Zborowska, Elizabeth ^a   Zaidi, Nasir H ^a   Liu, Lili ^a   Gordon, Nahida H ^b   Gerson, Stanton L ^a,c  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 O BENZYLGUANINE; CARMUSTINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; ANTINEOPLASTIC AGENT; DRUG DERIVATIVE; GUANINE; O(6) BENZYLGUANINE; O(6)-BENZYLGUANINE; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLON CANCER; CONTROLLED STUDY; DNA TRANSFECTION; DRUG CYTOTOXICITY; DRUG POTENTIATION; FEMALE; GROWTH INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR VOLUME; XENOGRAFT; ANIMAL; CELL CULTURE; COLON TUMOR; DNA REPAIR; DRUG EFFECT; DRUG RESISTANCE; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; NUDE MOUSE; PATHOLOGY;

ANIMALS; ANTINEOPLASTIC AGENTS; CARMUSTINE; COLONIC NEOPLASMS; DNA REPAIR; DRUG RESISTANCE, NEOPLASM; FEMALE; GUANINE; HUMANS; MICE; MICE, NUDE; NEOPLASM PROTEINS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0031279035     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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