-
1
-
-
0029089172
-
When more is less: Pathogenesis of glutamine repeat neurodegenerative diseases
-
Ross, C.A. (1995) When more is less: pathogenesis of glutamine repeat neurodegenerative diseases. Neuron, 15, 493-496.
-
(1995)
Neuron
, vol.15
, pp. 493-496
-
-
Ross, C.A.1
-
2
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
Huntington's Disease Collaborative Research Group. (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell, 72, 971-983.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
3
-
-
0027484673
-
Huntington's disease gene (IT15) is widely expressed in human and rat tissues
-
Li, S.-H., Schilling, G., Young, W.S., III, Li, X.-J., Margolis, R.L., Stine, O.C., Wagster, M.V., Abbott, M.H., Franz, M.L., Ranen, N.G., Folstein, S.E., Hedreen, J.C. and Ross, C.A. (1993) Huntington's disease gene (IT15) is widely expressed in human and rat tissues. Neuron, 11, 985-993.
-
(1993)
Neuron
, vol.11
, pp. 985-993
-
-
Li, S.-H.1
Schilling, G.2
Young III, W.S.3
Li, X.-J.4
Margolis, R.L.5
Stine, O.C.6
Wagster, M.V.7
Abbott, M.H.8
Franz, M.L.9
Ranen, N.G.10
Folstein, S.E.11
Hedreen, J.C.12
Ross, C.A.13
-
4
-
-
0029791355
-
Huntington disease: New insights into the relationship between CAG expansion and disease
-
Nasir, J., Goldberg, Y.P and Hayden, M.R. (1996) Huntington disease: new insights into the relationship between CAG expansion and disease. Hum. Mol. Genet., 5, 1431-1435.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1431-1435
-
-
Nasir, J.1
Goldberg, Y.P.2
Hayden, M.R.3
-
5
-
-
0028803757
-
A huntingtin-associated protein enriched in brain with implications for pathology
-
Li, X.-J., Li, S.-H., Sharp, A.H., Nucifora, F.C., Jr, Schilling, G., Lanahan, A., Worley, P., Snyder, S.H. and Ross, C.A. (1995) A huntingtin-associated protein enriched in brain with implications for pathology. Nature, 378, 398-402.
-
(1995)
Nature
, vol.378
, pp. 398-402
-
-
Li, X.-J.1
Li, S.-H.2
Sharp, A.H.3
Nucifora Jr., F.C.4
Schilling, G.5
Lanahan, A.6
Worley, P.7
Snyder, S.H.8
Ross, C.A.9
-
6
-
-
0030986659
-
HIP1, a human homologue of S.cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain
-
Kalchman, M.A., Koide, H.B., McCutcheon, K., Graham, R.K., Nichol, K., Nishiyama, K., Kazemi-Esfarjani, P., Lynn, F.C., Wellington, C., Metzler, M., Goldberg, Y.P., Kanazawa, I., Gietz, R.D. and Hayden, M.R. (1997) HIP1, a human homologue of S.cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain. Nature Genet., 16, 44-53.
-
(1997)
Nature Genet.
, vol.16
, pp. 44-53
-
-
Kalchman, M.A.1
Koide, H.B.2
McCutcheon, K.3
Graham, R.K.4
Nichol, K.5
Nishiyama, K.6
Kazemi-Esfarjani, P.7
Lynn, F.C.8
Wellington, C.9
Metzler, M.10
Goldberg, Y.P.11
Kanazawa, I.12
Gietz, R.D.13
Hayden, M.R.14
-
7
-
-
0031056478
-
HIP-I: A huntingtin interacting protein isolated by the yeast two-hybrid system
-
Wanker, E.E., Rovira, C., Scherzinger, E., Hasenbank, R., Walter, S., Tait, D., Colicelli, J. and Lehrach, H. (1997) HIP-I: A huntingtin interacting protein isolated by the yeast two-hybrid system. Hum. Mol. Genet., 6, 487-495.
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 487-495
-
-
Wanker, E.E.1
Rovira, C.2
Scherzinger, E.3
Hasenbank, R.4
Walter, S.5
Tait, D.6
Colicelli, J.7
Lehrach, H.8
-
8
-
-
0026639625
-
Protein interaction cloning in yeast: Identification of mammalian proteins that react with the leucine zipper of Jun
-
Chevray, P.M. and Nathans, D. (1992) Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun. Proc. Natl Acad. Sci. USA, 89, 5789-5793.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 5789-5793
-
-
Chevray, P.M.1
Nathans, D.2
-
9
-
-
0028124463
-
The two-hybrid system: An assay for protein-protein interactions
-
Fields, S. and Stemglanz, R. (1994) The two-hybrid system: an assay for protein-protein interactions. Trends Genet., 10, 286-292.
-
(1994)
Trends Genet.
, vol.10
, pp. 286-292
-
-
Fields, S.1
Stemglanz, R.2
-
10
-
-
0029952315
-
The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains
-
Debant, A., Serra-Pages, C., Seipel, K., O'Brien, S., Tang, M., Park, S.-H. and Streuli, M. (1996) The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains. Proc. Natl Acad. Sci. USA, 93, 5466-5471.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 5466-5471
-
-
Debant, A.1
Serra-Pages, C.2
Seipel, K.3
O'Brien, S.4
Tang, M.5
Park, S.-H.6
Streuli, M.7
-
11
-
-
10344242949
-
Novel proteins that interact with the COOH-terminal cytosolic routing determinants of an integral membrane peptide-processing enzyme
-
Alam, M.R., Caldwell, B.D., Johnson, R.C., Darlington, D.N., Mains, R.E. and Eipper, B.A. (1996) Novel proteins that interact with the COOH-terminal cytosolic routing determinants of an integral membrane peptide-processing enzyme. J. Biol. Chem., 271, 28636-28640.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 28636-28640
-
-
Alam, M.R.1
Caldwell, B.D.2
Johnson, R.C.3
Darlington, D.N.4
Mains, R.E.5
Eipper, B.A.6
-
12
-
-
0021272595
-
Erythrocyte spectrin is comprised of many homologous triple helical segments
-
Speicher, D.W. and Marchesi, V.T. (1984) Erythrocyte spectrin is comprised of many homologous triple helical segments. Nature, 311, 177-180.
-
(1984)
Nature
, vol.311
, pp. 177-180
-
-
Speicher, D.W.1
Marchesi, V.T.2
-
13
-
-
0025840254
-
Phasing the conformational unit of spectrin
-
Winograd, E., Hume, D. and Branton, D. (1991) Phasing the conformational unit of spectrin. Proc. Natl Acad. Sci. USA, 88, 10788-10791.
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 10788-10791
-
-
Winograd, E.1
Hume, D.2
Branton, D.3
-
14
-
-
0029899868
-
Huntingtin-associated protein (HAP1): Discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase
-
Li, X.-J., Sharp, A.H., Li, S.-H., Dawson, T.M., Snyder, S.H. and Ross, C.A. (1996) Huntingtin-associated protein (HAP1): discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase. Proc. Natl Acad. Sci. USA, 93, 4839-4844.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 4839-4844
-
-
Li, X.-J.1
Sharp, A.H.2
Li, S.-H.3
Dawson, T.M.4
Snyder, S.H.5
Ross, C.A.6
-
15
-
-
0029991245
-
Neurobiology of Huntington's disease
-
Sharp, A.H. and Ross, C.A. (1996) Neurobiology of Huntington's disease. Neurobiol. Dis., 3, 3-15.
-
(1996)
Neurobiol. Dis.
, vol.3
, pp. 3-15
-
-
Sharp, A.H.1
Ross, C.A.2
-
16
-
-
0027477946
-
Do effects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?
-
Beal, M.F., Hyman, B.T. and Koroshetz, W. (1993) Do effects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases? Trends Neurosci., 16, 125-131.
-
(1993)
Trends Neurosci.
, vol.16
, pp. 125-131
-
-
Beal, M.F.1
Hyman, B.T.2
Koroshetz, W.3
-
17
-
-
0028909139
-
Brain spectrin: Of mice and men
-
Goodman, S.R., Zimmer, W.E., Clark, M.B., Zagon, I.S., Barker, J.E. and Bloom, M.L. (1995) Brain spectrin: of mice and men. Brain Res. Bull., 36, 593-606.
-
(1995)
Brain Res. Bull.
, vol.36
, pp. 593-606
-
-
Goodman, S.R.1
Zimmer, W.E.2
Clark, M.B.3
Zagon, I.S.4
Barker, J.E.5
Bloom, M.L.6
-
18
-
-
0026034515
-
Modular organization of actin crosslinking proteins
-
Matsudaira, P. (1991) Modular organization of actin crosslinking proteins. Trends Biochem. Sci., 16, 87-92.
-
(1991)
Trends Biochem. Sci.
, vol.16
, pp. 87-92
-
-
Matsudaira, P.1
-
19
-
-
0030271515
-
Coiled coils: New structures and new functions
-
Lupas, A. (1996) Coiled coils: new structures and new functions. Trends Biochem. Sci., 21, 357-406.
-
(1996)
Trends Biochem. Sci.
, vol.21
, pp. 357-406
-
-
Lupas, A.1
-
20
-
-
0028077885
-
Troponin T is capable of binding dystrophin via a leucine zipper
-
Pearlman, J.A., Powaser, P.A., Elledge, S.J. and Caskey, C.T. (1994) Troponin T is capable of binding dystrophin via a leucine zipper. FEBS Lett., 354, 183-186.
-
(1994)
FEBS Lett.
, vol.354
, pp. 183-186
-
-
Pearlman, J.A.1
Powaser, P.A.2
Elledge, S.J.3
Caskey, C.T.4
-
21
-
-
0030035227
-
Identification of routing determinants in the cytosolic domain of a secretory granule-associated integral membrane protein
-
Milgram, S.L., Mains, R.E. and Eipper, B.A. (1996) Identification of routing determinants in the cytosolic domain of a secretory granule-associated integral membrane protein. J. Biol. Chem., 271, 17526-17535.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17526-17535
-
-
Milgram, S.L.1
Mains, R.E.2
Eipper, B.A.3
-
22
-
-
0029055601
-
Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form
-
Trottier, Y., Devys, D., Imbert, G., Saudou, F., An, I., Lutz, Y., Weber, C., Agid, Y., Hirsch, E.C. and Mandel, J.L. (1995) Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form. Nature Genet., 10, 104-110.
-
(1995)
Nature Genet.
, vol.10
, pp. 104-110
-
-
Trottier, Y.1
Devys, D.2
Imbert, G.3
Saudou, F.4
An, I.5
Lutz, Y.6
Weber, C.7
Agid, Y.8
Hirsch, E.C.9
Mandel, J.L.10
-
23
-
-
0029034511
-
Widespread expression of Huntington's disease gene (IT15) protein product
-
Sharp, A.H., Loev, S.J., Schilling, G., Li, S.-H. and Li, X.-J. (1995) Widespread expression of Huntington's disease gene (IT15) protein product. Neuron, 14, 1065-1074.
-
(1995)
Neuron
, vol.14
, pp. 1065-1074
-
-
Sharp, A.H.1
Loev, S.J.2
Schilling, G.3
Li, S.-H.4
Li, X.-J.5
-
24
-
-
0028989602
-
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
-
DiFiglia ,M., Sapp, E., Chase, K., Schwarz, C., Meloni, A., Young, C., Martin, E., Vonsattel, J.P, Carraway, R., Reeves, S.A., Boyce, F.M. and Aronin, N. (1995) Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons. Neuron, 14, 1075-1081.
-
(1995)
Neuron
, vol.14
, pp. 1075-1081
-
-
DiFiglia, M.1
Sapp, E.2
Chase, K.3
Schwarz, C.4
Meloni, A.5
Young, C.6
Martin, E.7
Vonsattel, J.P.8
Carraway, R.9
Reeves, S.A.10
Boyce, F.M.11
Aronin, N.12
-
25
-
-
0029152808
-
Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies
-
Gutekunst, C.A., Levey, A.I., Heilman, C.J., Whaley, W.L., Yi, H., Nash, N.R., Rees, H.D., Madden, J.J. and Hersch, S.M. (1995) Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies. Proc. Natl Acad. Sci. USA, 92, 8710-8714.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 8710-8714
-
-
Gutekunst, C.A.1
Levey, A.I.2
Heilman, C.J.3
Whaley, W.L.4
Yi, H.5
Nash, N.R.6
Rees, H.D.7
Madden, J.J.8
Hersch, S.M.9
-
26
-
-
0030973545
-
Kalirin, a cytosolic protein with spectrin-like and GDP/GTP exchange factor-like domains that interacts with peptidylglycine alpha-amidating monooxygenase, an integral membrane peptide-processing enzyme
-
Alam, M.R., Johnson, R.C., Darlington, D.N., Hand, T.A., Mains, R.E. and Eipper, B.A. (1997) Kalirin, a cytosolic protein with spectrin-like and GDP/GTP exchange factor-like domains that interacts with peptidylglycine alpha-amidating monooxygenase, an integral membrane peptide-processing enzyme. J. Biol. Chem., 272, 12667-12675.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12667-12675
-
-
Alam, M.R.1
Johnson, R.C.2
Darlington, D.N.3
Hand, T.A.4
Mains, R.E.5
Eipper, B.A.6
-
27
-
-
0029294676
-
Guanine nucleotide exchange factors: Activators of the Ras superfamily of proteins
-
Quilliam, L.A., Khosrave-Far, R., Huff, S.Y. and Der, C.J. (1995) Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins. Bioessays, 17, 395-404.
-
(1995)
Bioessays
, vol.17
, pp. 395-404
-
-
Quilliam, L.A.1
Khosrave-Far, R.2
Huff, S.Y.3
Der, C.J.4
-
28
-
-
0030267458
-
Rho: Theme and variations
-
Ridley, A.J. (1996) Rho: theme and variations. Curr. Biol., 6, 1256-1264.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1256-1264
-
-
Ridley, A.J.1
-
29
-
-
0030980641
-
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
-
Irani, K., Xia, Y., Zweier, J.L., Sollott, S.J., Der, C.J., Fearon, E.R., Sundaresan, M., Finkel, T. and Goldschmidt-Clermont, P.J. (1997) Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science, 275, 1649-1652.
-
(1997)
Science
, vol.275
, pp. 1649-1652
-
-
Irani, K.1
Xia, Y.2
Zweier, J.L.3
Sollott, S.J.4
Der, C.J.5
Fearon, E.R.6
Sundaresan, M.7
Finkel, T.8
Goldschmidt-Clermont, P.J.9
-
30
-
-
0028829750
-
The Rho's progress: A potential role during neuritogenesis for the Rho family of GTPases
-
Mackay, D.J.G., Nobes, C.D. and Hall, A. (1995) The Rho's progress: a potential role during neuritogenesis for the Rho family of GTPases. Trends Neurosci., 18, 496-501.
-
(1995)
Trends Neurosci.
, vol.18
, pp. 496-501
-
-
Mackay, D.J.G.1
Nobes, C.D.2
Hall, A.3
-
31
-
-
0021982117
-
Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease
-
Graveland, G.A., Williams, R.S. and DiFiglia, M. (1985) Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease. Science, 227, 770-774.
-
(1985)
Science
, vol.227
, pp. 770-774
-
-
Graveland, G.A.1
Williams, R.S.2
DiFiglia, M.3
-
32
-
-
0027377217
-
Evidence for neuronal degeneration and dendritic plasticity in cortical pyramidal neurons of Huntington's disease: A quantitative Golgi study
-
Sotrel, A., Williams, R.S., Kaufmann, W.E. and Myers, R.H. (1993) Evidence for neuronal degeneration and dendritic plasticity in cortical pyramidal neurons of Huntington's disease: a quantitative Golgi study. Neurology, 43, 2088-2095.
-
(1993)
Neurology
, vol.43
, pp. 2088-2095
-
-
Sotrel, A.1
Williams, R.S.2
Kaufmann, W.E.3
Myers, R.H.4
-
33
-
-
0023392945
-
High efficiency transformation of mammalian cells by plasmid DNA
-
Chen, C. and Okayama, H. (1987) High efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol., 7, 2745-2752.
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 2745-2752
-
-
Chen, C.1
Okayama, H.2
-
34
-
-
34547387652
-
Generation and analysis of 280,000 human expressed sequence tags
-
in press
-
Hillier, L. , Lennon, G., Becker, M., Bonaldo, M., Chiapelli, B., Chissoe, S., Dietrich, N., DuBuque, T., Favello, A., Gish, W., Hawkins, M., Holman, M., Hultman, M., Kucaba, T., Lacy, M., Le, M., Le, N., Mardis, E., Moore, B., Morris, M., Prange, C., Rifkin, L., Rohlfing, T., Schellenberg, K., Soares, M., Tan, F., Trevaskis, E., Underwood, K., Wohldmann, P., Waterston, R., Wilson, R. and Marra, M. (1997) Generation and analysis of 280,000 human expressed sequence tags. Genet. Res., in press.
-
(1997)
Genet. Res.
-
-
Hillier, L.1
Lennon, G.2
Becker, M.3
Bonaldo, M.4
Chiapelli, B.5
Chissoe, S.6
Dietrich, N.7
DuBuque, T.8
Favello, A.9
Gish, W.10
Hawkins, M.11
Holman, M.12
Hultman, M.13
Kucaba, T.14
Lacy, M.15
Le, M.16
Le, N.17
Mardis, E.18
Moore, B.19
Morris, M.20
Prange, C.21
Rifkin, L.22
Rohlfing, T.23
Schellenberg, K.24
Soares, M.25
Tan, F.26
Trevaskis, E.27
Underwood, K.28
Wohldmann, P.29
Waterston, R.30
Wilson, R.31
Marra, M.32
more..
-
35
-
-
0024062724
-
Molecular cloning and characterization of the human dbl proto-oncogene: Evidence that its overexpression is sufficient to transform NIH/3T3 cells
-
Ron, D., Tronick, S.R., Aaronson, S.A. and Eva, A. (1988) Molecular cloning and characterization of the human dbl proto-oncogene: evidence that its overexpression is sufficient to transform NIH/3T3 cells. EMBO J., 7, 2465-2473.
-
(1988)
EMBO J.
, vol.7
, pp. 2465-2473
-
-
Ron, D.1
Tronick, S.R.2
Aaronson, S.A.3
Eva, A.4
|