메뉴 건너뛰기




Volumn 169, Issue , 1999, Pages 81-92

Role of autoreactive CD8+ T cells in organ-specific autoimmune diseases: Insight from transgenic mouse models

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN;

EID: 0032795784     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-065X.1999.tb01308.x     Document Type: Review
Times cited : (40)

References (91)
  • 1
    • 0029954214 scopus 로고    scopus 로고
    • Insulin-dependent diabetes mellitus
    • 1. Tisch R. McDevitt HO. Insulin-dependent diabetes mellitus. Cell 1996;85:291-297.
    • (1996) Cell , vol.85 , pp. 291-297
    • Tisch, R.1    McDevitt, H.O.2
  • 2
    • 0031423760 scopus 로고    scopus 로고
    • The nonobese diabetic mouse as a model of autoimmune diabetes: Immune dysregulation gets the NOD
    • 2. Delovitch TL, Singh B. The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD. Immunity 1997;7:727-738.
    • (1997) Immunity , vol.7 , pp. 727-738
    • Delovitch, T.L.1    Singh, B.2
  • 3
    • 0030890588 scopus 로고    scopus 로고
    • Cell death mediators in autoimmune diabetes-no shortage of suspects
    • 3. Benoist C, Mathis D. Cell death mediators in autoimmune diabetes-no shortage of suspects. Cell 1997;89:1-3.
    • (1997) Cell , vol.89 , pp. 1-3
    • Benoist, C.1    Mathis, D.2
  • 5
    • 0023905731 scopus 로고
    • + T cell subsets are required for the transfer of diabetes in non-obese diabetic mice
    • + T cell subsets are required for the transfer of diabetes in non-obese diabetic mice. J lmmunol 1988;140:52-58.
    • (1988) J Lmmunol , vol.140 , pp. 52-58
    • Miller, B.1    Appel, M.2    O'Neill, J.3    Wicker, L.4
  • 6
    • 0026715030 scopus 로고
    • + T cells in autoimmune diabetes of NOD mice using transfer to NOD athymic nude mice
    • + T cells in autoimmune diabetes of NOD mice using transfer to NOD athymic nude mice. Eur J lmmunol 1992;22:2387-2393.
    • (1992) Eur J Lmmunol , vol.22 , pp. 2387-2393
    • Yagi, H.1
  • 8
    • 0025812205 scopus 로고
    • d monoclonal antibody
    • d monoclonal antibody. Diabetes 1991;40:1203-1209.
    • (1991) Diabetes , vol.40 , pp. 1203-1209
    • Taki, T.1
  • 10
    • 0032214715 scopus 로고    scopus 로고
    • Local expression of TNFα in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens
    • 10. Green EA, Eynon EE, Flavell RA. Local expression of TNFα in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens. Immunity 1998;9:733-743.
    • (1998) Immunity , vol.9 , pp. 733-743
    • Green, E.A.1    Eynon, E.E.2    Flavell, R.A.3
  • 11
    • 0032532280 scopus 로고    scopus 로고
    • + T and B lymphocytes
    • + T and B lymphocytes. J lmmunol 1998;161:4420-4427.
    • (1998) J Lmmunol , vol.161 , pp. 4420-4427
    • Balasa, B.1
  • 12
    • 0027367830 scopus 로고
    • Major histocompatibility complex class I molecules are required for the development of insulitis in nonobese diabetic mice
    • 12. Katz J. Benoist C. Mathis D. Major histocompatibility complex class I molecules are required for the development of insulitis in nonobese diabetic mice. Eur J lmmunol 1993;23:3358-3360.
    • (1993) Eur J Lmmunol , vol.23 , pp. 3358-3360
    • Katz, J.1    Benoist, C.2    Mathis, D.3
  • 14
    • 0031569582 scopus 로고    scopus 로고
    • Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent
    • 14. Serreze DV, et al. Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent. J Immunol 1997;158:3978-3986.
    • (1997) J Immunol , vol.158 , pp. 3978-3986
    • Serreze, D.V.1
  • 15
    • 0032514701 scopus 로고    scopus 로고
    • Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor α chain gene rearrangement
    • 15. Di Lorenzo T, et al. Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor α chain gene rearrangement. Proc Natl Acad Sci USA 1998;95:12538-12543.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12538-12543
    • Di Lorenzo, T.1
  • 16
    • 0030022742 scopus 로고    scopus 로고
    • Transfer of diabetes in the NOD-scid mouse by CD4 T-cell clones. Differential requirement for CD8 T-cells
    • 16 Peterson JD, Haskins K. Transfer of diabetes in the NOD-scid mouse by CD4 T-cell clones. Differential requirement for CD8 T-cells. Diabetes 1996;45:328-336.
    • (1996) Diabetes , vol.45 , pp. 328-336
    • Peterson, J.D.1    Haskins, K.2
  • 18
    • 0029030964 scopus 로고
    • T helper cell subsets in insulin dependent diabetes
    • 18. Kau. J, Benoist C, Mathis D. T helper cell subsets in insulin dependent diabetes. Science 1995;268:1185-1188.
    • (1995) Science , vol.268 , pp. 1185-1188
    • Kau, J.1    Benoist, C.2    Mathis, D.3
  • 20
    • 13344294394 scopus 로고    scopus 로고
    • CD8 t cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells
    • 20. Wong FS. Visintin I, Flavell RA, Janeway CA. CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells. J Exp Med 1996;183:67-76.
    • (1996) J Exp Med , vol.183 , pp. 67-76
    • Wong, F.S.1    Visintin, I.2    Flavell, R.A.3    Janeway, C.A.4
  • 21
    • 8544222762 scopus 로고    scopus 로고
    • CD8 cytotoxic T-cell clone rapidly transfers autoimmune diabetes in very young NOD and MHC class I-compatible scid mice
    • 21. Yoneda R, et al, CD8 cytotoxic T-cell clone rapidly transfers autoimmune diabetes in very young NOD and MHC class I-compatible scid mice. Diabetologia 1997;40:1044-1052.
    • (1997) Diabetologia , vol.40 , pp. 1044-1052
    • Yoneda, R.1
  • 22
    • 0030890721 scopus 로고    scopus 로고
    • The role of Fas in autoimmune diabetes
    • 22. Chervonsky AV, et al. The role of Fas in autoimmune diabetes. Cell 1997;89:17-24.
    • (1997) Cell , vol.89 , pp. 17-24
    • Chervonsky, A.V.1
  • 23
    • 0032506224 scopus 로고    scopus 로고
    • Mechanisms of β cell death in diabetes: A minor role for CD95
    • 23. Allison J, Strasser A. Mechanisms of β cell death in diabetes: a minor role for CD95. Proc Natl Acad Sci USA 1998;95:13818-13822.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13818-13822
    • Allison, J.1    Strasser, A.2
  • 24
    • 1842289172 scopus 로고    scopus 로고
    • Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice
    • 24. Kägi D, et al. Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice. J Exp Med 1997;186:989-997.
    • (1997) J Exp Med , vol.186 , pp. 989-997
    • Kägi, D.1
  • 25
    • 0024817093 scopus 로고
    • + lymphocytes in autoimmune disease. Studies on spontaneous and adoptively transferred diabetes in nonobese diabetic mice
    • + lymphocytes in autoimmune disease. Studies on spontaneous and adoptively transferred diabetes in nonobese diabetic mice. J Immunol 1989;143:3994-3999.
    • (1989) J Immunol , vol.143 , pp. 3994-3999
    • Young, L.H.1    Peterson, L.B.2    Wicker, L.S.3    Persechini, P.M.4    Young, J.D.E.5
  • 26
    • 0025754853 scopus 로고
    • Virus infection triggers insulin-dependent diabetes mellitus in a transgeneic model: Role of anti-self (virus) immune response
    • 26. Oldstone MBA, Nerenberg M, Southern P, Price J, Lewicki H. Virus infection triggers insulin-dependent diabetes mellitus in a transgeneic model: role of anti-self (virus) immune response. Cell 1991;65:319-331.
    • (1991) Cell , vol.65 , pp. 319-331
    • Oldstone, M.B.A.1    Nerenberg, M.2    Southern, P.3    Price, J.4    Lewicki, H.5
  • 27
    • 0025755292 scopus 로고
    • Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice
    • 27. Ohashi PS, et al. Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell 1991;65:305-317.
    • (1991) Cell , vol.65 , pp. 305-317
    • Ohashi, P.S.1
  • 28
    • 0027184741 scopus 로고
    • Autoimmune diabetes can be induced in transgenic major histocompatibility complex class II-deficient mice
    • 18. laufer TM, et al. Autoimmune diabetes can be induced in transgenic major histocompatibility complex class II-deficient mice. J Exp Med 1993;178:589-596.
    • (1993) J Exp Med , vol.178 , pp. 589-596
    • Laufer, T.M.1
  • 29
    • 0028446546 scopus 로고
    • How virus induces a rapid or slow onset insulin dependent diabetes mellitus in a transgeneic model
    • 29. Von Herrath MG, Dockter J, Oldstone M. How virus induces a rapid or slow onset insulin dependent diabetes mellitus in a transgeneic model. Immunity 1994;1:231-142.
    • (1994) Immunity , vol.1 , pp. 231-1142
    • Von Herrath, M.G.1    Dockter, J.2    Oldstone, M.3
  • 30
    • 0032213343 scopus 로고    scopus 로고
    • In vivo treatment with a MHC class I-restricted blocking peptide can prevent virus-induced autoimmune diabetes
    • 30. Von Herrath MG, et al. In vivo treatment with a MHC class I-restricted blocking peptide can prevent virus-induced autoimmune diabetes. J Iminunol 1998;161:5087-5096.
    • (1998) J Iminunol , vol.161 , pp. 5087-5096
    • Von Herrath, M.G.1
  • 31
    • 0029551987 scopus 로고
    • Coexpression of B7-1 and viral ("self") transgenes in pancreatic β cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes
    • 31. Von Herrath MG, Guerder S, Lewicki H, Flawell RA, Oldstone MB, Coexpression of B7-1 and viral ("self") transgenes in pancreatic β cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes. Immunity 1995;3:727-38.
    • (1995) Immunity , vol.3 , pp. 727-738
    • Von Herrath, M.G.1    Guerder, S.2    Lewicki, H.3    Flawell, R.A.4    Oldstone, M.B.5
  • 32
    • 0029942839 scopus 로고    scopus 로고
    • Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytoxicity
    • 32. Kagi D, Odermatt B. Ohashi PS, Zinkernagel RM, Hentgartner H. Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytoxicity. J Exp Med 1996;183:2143-2112.
    • (1996) J Exp Med , vol.183 , pp. 2143-12112
    • Kagi, D.1    Odermatt, B.2    Ohashi, P.S.3    Zinkernagel, R.M.4    Hentgartner, H.5
  • 33
    • 0030210309 scopus 로고    scopus 로고
    • + T cell-mediated spontaneous diabetes in neonatal mice
    • + T cell-mediated spontaneous diabetes in neonatal mice. J Immunol 1996;157:978-983.
    • (1996) J Immunol , vol.157 , pp. 978-983
    • Morgan, D.J.1
  • 34
    • 0026571924 scopus 로고
    • + T cells
    • + T cells. Eur J Immunol 1992;22:1013-1022.
    • (1992) Eur J Immunol , vol.22 , pp. 1013-1022
    • Lo, D.1
  • 35
    • 0028582150 scopus 로고
    • On the various manifestations of spontaneous autoimmune diabetes in rodent models
    • 35. Degermann S, et al. On the various manifestations of spontaneous autoimmune diabetes in rodent models. Eur J Immunol 1994;24:3155-3160.
    • (1994) Eur J Immunol , vol.24 , pp. 3155-3160
    • Degermann, S.1
  • 36
    • 0028409436 scopus 로고
    • A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity
    • 36. Scott B, et al, A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity Immunity 1994;1:73-82.
    • (1994) Immunity , vol.1 , pp. 73-82
    • Scott, B.1
  • 37
    • 0032076047 scopus 로고    scopus 로고
    • Allelic inclusion of T cell receptor α genes poses an autoimmune hazard due to low-level expression of autospecific receptors
    • 37. Sarukhan A. Garda C, Lanoue A, von Boehmer H. Allelic inclusion of T cell receptor α genes poses an autoimmune hazard due to low-level expression of autospecific receptors. Immunity 1998;8:563-570.
    • (1998) Immunity , vol.8 , pp. 563-570
    • Sarukhan, A.1    Garda, C.2    Lanoue, A.3    Von Boehmer, H.4
  • 38
    • 0032538918 scopus 로고    scopus 로고
    • + T cells expressing endogenous T cell receptor chains protect rnyelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis
    • + T cells expressing endogenous T cell receptor chains protect rnyelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis. J Exp Med 1998;188:1883-1894.
    • (1998) J Exp Med , vol.188 , pp. 1883-1894
    • Olivares-Villagomez, D.1    Wang, Y.2    Lafaille, J.J.3
  • 40
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • 40. Matzinger P. Tolerance, danger, and the extended family. Annu Rev Immunol 1994;12:991-1045.
    • (1994) Annu Rev Immunol , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 41
    • 0029807595 scopus 로고    scopus 로고
    • Induction of autoimmune diabetes by oral administration of autoantigen
    • 41. Blanas E, Carbone FR, Allison J, Miller JFAP, Heath WR. Induction of autoimmune diabetes by oral administration of autoantigen. Science 1996;274:1707-1709.
    • (1996) Science , vol.274 , pp. 1707-1709
    • Blanas, E.1    Carbone, F.R.2    Allison, J.3    Miller, J.F.A.P.4    Heath, W.R.5
  • 42
    • 0031821976 scopus 로고    scopus 로고
    • Major histocompatibility complex class I-restricted cross-presentation is biased towards high dose antigens and those released during cellular destruction
    • 42. Kurts C, Miller JFAP, Subramaniam RM, Carbone FR, Heath WR. Major histocompatibility complex class I-restricted cross-presentation is biased towards high dose antigens and those released during cellular destruction. J Exp Med 1998;188:409-414.
    • (1998) J Exp Med , vol.188 , pp. 409-414
    • Kurts, C.1    Miller, J.F.A.P.2    Subramaniam, R.M.3    Carbone, F.R.4    Heath, W.R.5
  • 43
    • 0030724897 scopus 로고    scopus 로고
    • Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice
    • 43. Verdaguer J, et al. Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice. J Exp Med 1997;186:1663-1676.
    • (1997) J Exp Med , vol.186 , pp. 1663-1676
    • Verdaguer, J.1
  • 45
    • 0024500755 scopus 로고
    • T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice
    • 45. Boitard C, Yasunami R, Dardenne M, Bach JF, T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice. J Exp Med 1989;169:1669-1680.
    • (1989) J Exp Med , vol.169 , pp. 1669-1680
    • Boitard, C.1    Yasunami, R.2    Dardenne, M.3    Bach, J.F.4
  • 46
    • 0032538820 scopus 로고    scopus 로고
    • + T cells prevent spontaneous experimental autoimmune encephalomyelitis in anti-myelin basic protein T cell receptor transgenic mice
    • + T cells prevent spontaneous experimental autoimmune encephalomyelitis in anti-myelin basic protein T cell receptor transgenic mice. J Exp Med 1998;188:1875-1882.
    • (1998) J Exp Med , vol.188 , pp. 1875-1882
    • De Van Keere, F.1    Tonewaga, S.2
  • 47
    • 0029812040 scopus 로고    scopus 로고
    • Constitutive class I-restricted exogenous presentation of self antigens in vivo
    • 47. Kurts C, et al. Constitutive class I-restricted exogenous presentation of self antigens in vivo. J Exp Med 1996;184:923-930.
    • (1996) J Exp Med , vol.184 , pp. 923-930
    • Kurts, C.1
  • 48
    • 0032485487 scopus 로고    scopus 로고
    • Bhardwaj dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
    • 48. Albert ML, Sauter B, Bhardwaj Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 1998;392:86-89
    • (1998) Nature , vol.392 , pp. 86-89
    • Albert, M.L.1    Sauter, B.2
  • 49
    • 0026717868 scopus 로고
    • A fail-safe mechanism for maintaining self tolerance
    • 49. Guerder S, Matzinger P. A fail-safe mechanism for maintaining self tolerance. J Exp Med 1992;176:553-564.
    • (1992) J Exp Med , vol.176 , pp. 553-564
    • Guerder, S.1    Matzinger, P.2
  • 50
    • 0031467003 scopus 로고    scopus 로고
    • + T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity
    • + T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity. J Exp Med 1997;186:2057-2061.
    • (1997) J Exp Med , vol.186 , pp. 2057-2061
    • Kurts, C.1
  • 51
    • 0029845747 scopus 로고    scopus 로고
    • T cell responses are governed by avidity and costimulatory thresholds
    • 51. Rachmann MF, et al. T cell responses are governed by avidity and costimulatory thresholds. Eur J Immunol 1996;26:2017.
    • (1996) Eur J Immunol , vol.26 , pp. 2017
    • Rachmann, M.F.1
  • 52
    • 0031922954 scopus 로고    scopus 로고
    • + T tell activation
    • + T tell activation. Int Immunol 1998;10:619-630.
    • (1998) Int Immunol , vol.10 , pp. 619-630
    • Pardigon, N.1
  • 53
    • 0032192470 scopus 로고    scopus 로고
    • CD8 expression allows T cell signaling by monomeric peptide MHC complexes
    • 53. Delon J. et al. CD8 expression allows T cell signaling by monomeric peptide MHC complexes. Immunity 1998;9:467-473.
    • (1998) Immunity , vol.9 , pp. 467-473
    • Delon, J.1
  • 54
    • 0032192469 scopus 로고    scopus 로고
    • Initiation of signal transduction through the T cell receptor requires the peptide multivalent engagement of MHC ligands
    • 54. Boniface JJ, et al. Initiation of signal transduction through the T cell receptor requires the peptide multivalent engagement of MHC ligands. Immunity 1998;9:459-466.
    • (1998) Immunity , vol.9 , pp. 459-466
    • Boniface, J.J.1
  • 55
    • 0028199631 scopus 로고
    • Mice expressing both B7. I and viral glycoprotein on pancreatic β cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T lymphocyte unresponsiveness
    • 55. Harlan DM, et al. Mice expressing both B7. I and viral glycoprotein on pancreatic β cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T lymphocyte unresponsiveness. Proc Natl Acad Sci USA 1994;91:3137-3141
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3137-3141
    • Harlan, D.M.1
  • 56
    • 0032549142 scopus 로고    scopus 로고
    • Structural basis of plasticity in T cell receptor recognition of a self neptide-MHC antigen
    • 56. Garcia KC, et al. Structural basis of plasticity in T cell receptor recognition of a self neptide-MHC antigen. Science 1998;279:1116-1172.
    • (1998) Science , vol.279 , pp. 1116-1172
    • Garcia, K.C.1
  • 57
    • 0030925578 scopus 로고    scopus 로고
    • Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone
    • 57. Hemmer B, et al. Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone. J Exp Med 1997;185:1651-1659.
    • (1997) J Exp Med , vol.185 , pp. 1651-1659
    • Hemmer, B.1
  • 58
    • 0026694021 scopus 로고
    • -/- mice
    • -/- mice. Science 1992;256:1210-1213.
    • (1992) Science , vol.256 , pp. 1210-1213
    • Koh, D.R.1
  • 59
    • 0026647293 scopus 로고
    • + T cells in murine experimental allergic encephalomyelitis
    • + T cells in murine experimental allergic encephalomyelitis. Science 1992;256:1213-1215.
    • (1992) Science , vol.256 , pp. 1213-1215
    • Jiang, H.1    Zhang, S.I.2    Pernis, B.3
  • 61
    • 0031573087 scopus 로고    scopus 로고
    • Recombinant T cell receptor molecules can prevent and reverse experimental autoimmune encephalomyelitis: Dose effects and involvement of both CD4 and CD8 T cells
    • 61. Kumar V, et al. Recombinant T cell receptor molecules can prevent and reverse experimental autoimmune encephalomyelitis: dose effects and involvement of both CD4 and CD8 T cells, J Immunol 1997;159:5150-5156.
    • (1997) J Immunol , vol.159 , pp. 5150-5156
    • Kumar, V.1
  • 63
    • 0026542168 scopus 로고
    • Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor β after antigen-specific triggering
    • 63. Miller A, Lider O, Roberts AB, Sporn MB, Weiner HL, Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor β after antigen-specific triggering. Proc Natl Acad Sci USA 1992;89:421-425.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 421-425
    • Miller, A.1    Lider, O.2    Roberts, A.B.3    Sporn, M.B.4    Weiner, H.L.5
  • 65
    • 0027143575 scopus 로고
    • Competitive PCR quantification of CD4, CD8, ICAM-1, VCAM-1, and MHC class II mRNA in the central nervous system during the development and resolution of experimental allergic encephalomyelitis
    • 65. Lindsey JW, Steinman L. Competitive PCR quantification of CD4, CD8, ICAM-1, VCAM-1, and MHC class II mRNA in the central nervous system during the development and resolution of experimental allergic encephalomyelitis. J Neuroimmunol 1993;48:227-234.
    • (1993) J Neuroimmunol , vol.48 , pp. 227-234
    • Lindsey, J.W.1    Steinman, L.2
  • 66
    • 0030712367 scopus 로고    scopus 로고
    • Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells
    • 66. Zhang BN, Yamamura T, Kondo T, Fujiwara M, Tabira T. Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells J Exp Med 1997;186:1677-1687.
    • (1997) J Exp Med , vol.186 , pp. 1677-1687
    • Zhang, B.N.1    Yamamura, T.2    Kondo, T.3    Fujiwara, M.4    Tabira, T.5
  • 67
    • 0030443139 scopus 로고    scopus 로고
    • Viral infection of transgenic mice expressing a viral protein in oligodendrocytes leads to chronic central nervous system autoimmune disease
    • 67. Evans CF, Horwitz MS, Hobbs MV, Oldstone MBA. Viral infection of transgenic mice expressing a viral protein in oligodendrocytes leads to chronic central nervous system autoimmune disease, J Exp Med 1996;184:2371-2384.
    • (1996) J Exp Med , vol.184 , pp. 2371-2384
    • Evans, C.F.1    Horwitz, M.S.2    Hobbs, M.V.3    Oldstone, M.B.A.4
  • 69
    • 0018859801 scopus 로고
    • Loss of suppression T cells in active multiple sclerosis
    • 69. Reinhertz EL, et al. Loss of suppression T cells in active multiple sclerosis. N Engl J Med 1980;303:125-129.
    • (1980) N Engl J Med , vol.303 , pp. 125-129
    • Reinhertz, E.L.1
  • 70
    • 0031945583 scopus 로고    scopus 로고
    • CD4 and CD8 lymphocyte subsets in cerebrospinal fluid and peripheral blood from patients with multiple sclerosis, meningitis and normal controls
    • 70. Vrethem M, et al, CD4 and CD8 lymphocyte subsets in cerebrospinal fluid and peripheral blood from patients with multiple sclerosis, meningitis and normal controls. Ada Neurol Scand 1998;97:215-220.
    • (1998) Ada Neurol Scand , vol.97 , pp. 215-220
    • Vrethem, M.1
  • 71
    • 0031821271 scopus 로고    scopus 로고
    • + T cells make discrete contributions to demyelination and neurologic disease in a viral model of multiple sclerosis
    • + T cells make discrete contributions to demyelination and neurologic disease in a viral model of multiple sclerosis. J Virol 1998;72:7310-7329.
    • (1998) J Virol , vol.72 , pp. 7310-7329
    • Murray, P.D.1    Pavelko, K.D.2    Leibowitz, J.3    Lin, X.4    Rodriguez, M.5
  • 72
    • 0022459287 scopus 로고
    • Immunohistochemical staining of human brain with monoclonal antibodies that identify lymphocytes, monocytes and Ia antigen
    • 72. Hauser SL, et al. Immunohistochemical staining of human brain with monoclonal antibodies that identify lymphocytes, monocytes and Ia antigen. Ann Neurol 1986;19:578-587.
    • (1986) Ann Neurol , vol.19 , pp. 578-587
    • Hauser, S.L.1
  • 73
    • 0023230316 scopus 로고
    • Multiple sclerosis: Relevance of class I and class II MHC-expressing cells to lesion development
    • 73. Traugou U. Multiple sclerosis: relevance of class I and class II MHC-expressing cells to lesion development. J Neuroimmunol 1987;16:283-302.
    • (1987) J Neuroimmunol , vol.16 , pp. 283-302
    • Traugou, U.1
  • 74
    • 0030056764 scopus 로고    scopus 로고
    • Distinct patterns of multiple sclerosis pathology indicates heterogeneity of pathogenesis
    • 74. Lucchinetti CF, Bruck W, Rodriguez M, Lassman H. Distinct patterns of multiple sclerosis pathology indicates heterogeneity of pathogenesis. Brain Pathol 1996;6:259-274.
    • (1996) Brain Pathol , vol.6 , pp. 259-274
    • Lucchinetti, C.F.1    Bruck, W.2    Rodriguez, M.3    Lassman, H.4
  • 75
    • 0009600557 scopus 로고    scopus 로고
    • Multiple sclerosis: A modifying influence of HLA class I in an HLA class II associated autoimmune disease
    • 75. Fogdell-Hahn A, Ligers A, Gronning M, Hillert J, Olerup O. Multiple sclerosis: a modifying influence of HLA class I in an HLA class II associated autoimmune disease J Neuroimmunol 1998;90:103.
    • (1998) J Neuroimmunol , vol.90 , pp. 103
    • Fogdell-Hahn, A.1    Ligers, A.2    Gronning, M.3    Hillert, J.4    Olerup, O.5
  • 76
    • 0028143869 scopus 로고
    • + T-cell responses to human myelin protein-derived peptides
    • + T-cell responses to human myelin protein-derived peptides. Proc Natl Acad Sci USA 1994;91:10859-10863.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10859-10863
    • Tsuchida, T.1
  • 77
    • 0031573209 scopus 로고    scopus 로고
    • Autoantigen recognition by human CD8 T cell clones. Enhanced agonist response induced by altered peptide ligands
    • 77. Dressel A, et al. Autoantigen recognition by human CD8 T cell clones. Enhanced agonist response induced by altered peptide ligands, J Immunol 1997;159:4943-951.
    • (1997) J Immunol , vol.159 , pp. 4943-4951
    • Dressel, A.1
  • 78
    • 0031048921 scopus 로고    scopus 로고
    • + cytotoxic T lymphocytes restricted by HLA-A3: Evidence for cross-reactivity with an environmental microorganism
    • + cytotoxic T lymphocytes restricted by HLA-A3: evidence for cross-reactivity with an environmental microorganism. J Neuroimmunol 1997;73:7-14.
    • (1997) J Neuroimmunol , vol.73 , pp. 7-14
    • Honma, K.1
  • 79
    • 0032497524 scopus 로고    scopus 로고
    • Direct visualization of antigen-specific cytotoxic T cells. A new insight into immune defenses
    • 79. Schwartz R. Direct visualization of antigen-specific cytotoxic T cells. A new insight into immune defenses. N Engl J Med 1998;339:1076-1078.
    • (1998) N Engl J Med , vol.339 , pp. 1076-1078
    • Schwartz, R.1
  • 80
    • 0032521030 scopus 로고    scopus 로고
    • MHC class I-restricted lysis of human oligodendrocytes by myelin basic protein peptide-specific CD8 T lymphocytes
    • 80. Jurewicz A, Biddison WE, Antel JP. MHC class I-restricted lysis of human oligodendrocytes by myelin basic protein peptide-specific CD8 T lymphocytes. J Immunol 1998;160:3056-3059.
    • (1998) J Immunol , vol.160 , pp. 3056-3059
    • Jurewicz, A.1    Biddison, W.E.2    Antel, J.P.3
  • 81
  • 82
    • 0031786356 scopus 로고    scopus 로고
    • Tumor-specific killer cells in paraneoplastic cerebellar degeneration
    • 82. Albert ML, et al. Tumor-specific killer cells in paraneoplastic cerebellar degeneration, Nat Med 1998;4:1321-1324.
    • (1998) Nat Med , vol.4 , pp. 1321-1324
    • Albert, M.L.1
  • 84
    • 0032168898 scopus 로고    scopus 로고
    • Regulation of class I MHC gene expression in the developing and mature CNS by neural activity
    • 84. Corriveau RA, Huh GS, Shatz CJ. Regulation of class I MHC gene expression in the developing and mature CNS by neural activity. Neuron 1998;21:505-520.
    • (1998) Neuron , vol.21 , pp. 505-520
    • Corriveau, R.A.1    Huh, G.S.2    Shatz, C.J.3
  • 85
    • 0021875480 scopus 로고
    • In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis
    • 85. Bottazzo GF, et al. In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis. N Engl J Med 1985;313:353-360.
    • (1985) N Engl J Med , vol.313 , pp. 353-360
    • Bottazzo, G.F.1
  • 86
    • 0027361654 scopus 로고
    • Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients
    • 86. Itoh N, et al. Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients. J Clin Invest 1993;92:2313-2322.
    • (1993) J Clin Invest , vol.92 , pp. 2313-2322
    • Itoh, N.1
  • 87
    • 0028278373 scopus 로고
    • Pancreas in recent onset insulin-dependent diabetes mellitus
    • 87. Somoza N, et al. Pancreas in recent onset insulin-dependent diabetes mellitus. J Immunol 1994;153:1360-1377.
    • (1994) J Immunol , vol.153 , pp. 1360-1377
    • Somoza, N.1
  • 88
  • 91
    • 0031465256 scopus 로고    scopus 로고
    • Systemic antigen in the treatment of T cell-mediated autoimmune diseases
    • 91. Liblau R, Tisch R, Bercovici N, McDevitt HO. Systemic antigen in the treatment of T cell-mediated autoimmune diseases. Immunol Today 1997;18:599-604.
    • (1997) Immunol Today , vol.18 , pp. 599-604
    • Liblau, R.1    Tisch, R.2    Bercovici, N.3    McDevitt, H.O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.