-
1
-
-
0023857965
-
Specific chromosomal abnormalities in malignant human gliomas
-
Bigner SH, Mark J, Burger PC, et al. Specific chromosomal abnormalities in malignant human gliomas. Cancer Res 1988;48: 405-11
-
(1988)
Cancer Res
, vol.48
, pp. 405-411
-
-
Bigner, S.H.1
Mark, J.2
Burger, P.C.3
-
2
-
-
0023708370
-
Clonal genomic alterations in glioma malignancy stages
-
James CD, Carlbom E, Dumanski JP, et al. Clonal genomic alterations in glioma malignancy stages. Cancer Res 1988;48:5546-51
-
(1988)
Cancer Res
, vol.48
, pp. 5546-5551
-
-
James, C.D.1
Carlbom, E.2
Dumanski, J.P.3
-
3
-
-
0027167694
-
Deletion mapping of the long arm of chromosome 10 in glioblastoma multiforme
-
Fults D, Pedone C. Deletion mapping of the long arm of chromosome 10 in glioblastoma multiforme. Genes Chromosom Cancer 1993;7:173-77
-
(1993)
Genes Chromosom Cancer
, vol.7
, pp. 173-177
-
-
Fults, D.1
Pedone, C.2
-
4
-
-
0027208575
-
Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10
-
Karlbom AE, James CD, Boethius J, et al. Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10. Hum Genet 1993;92:169-74
-
(1993)
Hum Genet
, vol.92
, pp. 169-174
-
-
Karlbom, A.E.1
James, C.D.2
Boethius, J.3
-
5
-
-
0029024891
-
Chromosome 10 deletion mapping in human gliomas: A common deletion region in 10q25
-
Rasheed BKA, McLendon RE, Friedman HS, et al. Chromosome 10 deletion mapping in human gliomas: A common deletion region in 10q25. Oncogene 1995;10:2243-46
-
(1995)
Oncogene
, vol.10
, pp. 2243-2246
-
-
Rasheed, B.K.A.1
McLendon, R.E.2
Friedman, H.S.3
-
6
-
-
0029992049
-
Deletion mapping of gliomas suggest the presence of two small regions for candidate tumor-suppressor genes in a 17-cM interval on chromosome 10q
-
Albarosa R, Colombo BM, Roz L, et al. Deletion mapping of gliomas suggest the presence of two small regions for candidate tumor-suppressor genes in a 17-cM interval on chromosome 10q. Am J Hum Genet 1996;58:1260-67
-
(1996)
Am J Hum Genet
, vol.58
, pp. 1260-1267
-
-
Albarosa, R.1
Colombo, B.M.2
Roz, L.3
-
7
-
-
0030009382
-
Deletion mapping of chromosome 10 in human glioma
-
Sonoda Y, Murakami Y, Tominaga T, Kayama T, Yoshimoto T, Sekiya T. Deletion mapping of chromosome 10 in human glioma. Jpn J Cancer Res 1996;87:363-67
-
(1996)
Jpn J Cancer Res
, vol.87
, pp. 363-367
-
-
Sonoda, Y.1
Murakami, Y.2
Tominaga, T.3
Kayama, T.4
Yoshimoto, T.5
Sekiya, T.6
-
8
-
-
0031967883
-
Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades
-
Ichimura K, Schmidt EE, Miyakawa A, Goike HM, Collins VP. Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades. Genes Chromosom Cancer 1998;22:9-15
-
(1998)
Genes Chromosom Cancer
, vol.22
, pp. 9-15
-
-
Ichimura, K.1
Schmidt, E.E.2
Miyakawa, A.3
Goike, H.M.4
Collins, V.P.5
-
9
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li J, Yen C, Liaw D, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer [see comments]. Science 1997;275:1943-47
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
-
10
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck PA, Pershouse MA, Jasser SA, et al. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nature Genet 1997;15:356-62
-
(1997)
Nature Genet
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
-
11
-
-
0031001041
-
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta
-
Li DM, Sun H. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta. Cancer Res 1997;57:2124-29
-
(1997)
Cancer Res
, vol.57
, pp. 2124-2129
-
-
Li, D.M.1
Sun, H.2
-
12
-
-
0030837555
-
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
-
Myers MP, Stolarov JP, Eng C, et al. P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci USA 1997;94:9052-57
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 9052-9057
-
-
Myers, M.P.1
Stolarov, J.P.2
Eng, C.3
-
13
-
-
14444269482
-
MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines
-
Teng DH, Hu R, Lin H, et al. MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines. Cancer Res 1997;57: 5221-25
-
(1997)
Cancer Res
, vol.57
, pp. 5221-5225
-
-
Teng, D.H.1
Hu, R.2
Lin, H.3
-
14
-
-
0030801275
-
Mutation analysis of the putative tumor suppressor gene PTEN/ MMAC1 in primary breast carcinomas
-
Rhei E, Kang L, Bogomolniy F, Federici MG, Borgen PI, Boyd J. Mutation analysis of the putative tumor suppressor gene PTEN/ MMAC1 in primary breast carcinomas. Cancer Res 1997;57: 3657-59
-
(1997)
Cancer Res
, vol.57
, pp. 3657-3659
-
-
Rhei, E.1
Kang, L.2
Bogomolniy, F.3
Federici, M.G.4
Borgen, P.I.5
Boyd, J.6
-
15
-
-
15444349266
-
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer
-
Cairns P, Okami K, Halachmi S, et al. Frequent inactivation of PTEN/MMAC1 in primary prostate cancer. Cancer Res 1997;57: 4997-5000
-
(1997)
Cancer Res
, vol.57
, pp. 4997-5000
-
-
Cairns, P.1
Okami, K.2
Halachmi, S.3
-
16
-
-
0030730905
-
Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors
-
Dahia PL, Marsh DJ, Zheng Z, et al. Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors. Cancer Res 1997;57:4710-13
-
(1997)
Cancer Res
, vol.57
, pp. 4710-4713
-
-
Dahia, P.L.1
Marsh, D.J.2
Zheng, Z.3
-
17
-
-
0030761409
-
Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies
-
Tashiro H, Blazes MS, Wu R, et al. Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res 1997;57:3935-40
-
(1997)
Cancer Res
, vol.57
, pp. 3935-3940
-
-
Tashiro, H.1
Blazes, M.S.2
Wu, R.3
-
18
-
-
0030777104
-
Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma
-
Guldberg P, Straten P, Birck A, Ahrenkiel V, Kirkin AF, Zeuthen J. Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma. Cancer Res 1997;57: 3660-63
-
(1997)
Cancer Res
, vol.57
, pp. 3660-3663
-
-
Guldberg, P.1
Straten, P.2
Birck, A.3
Ahrenkiel, V.4
Kirkin, A.F.5
Zeuthen, J.6
-
19
-
-
0030724320
-
PTEN/ MMAC1 mutations and EGFR amplification in glioblastomas
-
Liu W, James CD, Frederick L, Alderete BE, Jenkins RB. PTEN/ MMAC1 mutations and EGFR amplification in glioblastomas. Cancer Res 1997;57:5254-57
-
(1997)
Cancer Res
, vol.57
, pp. 5254-5257
-
-
Liu, W.1
James, C.D.2
Frederick, L.3
Alderete, B.E.4
Jenkins, R.B.5
-
20
-
-
0030799909
-
Somatic mutations of PTEN in glioblastoma multiforme
-
Wang SI, Pue J, Li J, et al. Somatic mutations of PTEN in glioblastoma multiforme. Cancer Res 1997;57:4183-86
-
(1997)
Cancer Res
, vol.57
, pp. 4183-4186
-
-
Wang, S.I.1
Pue, J.2
Li, J.3
-
21
-
-
0030817576
-
PTEN gene mutations are seen in high-grade but not in low-grade gliomas
-
Rasheed BK, Stenzel TT, McLendon RE, et al. PTEN gene mutations are seen in high-grade but not in low-grade gliomas. Cancer Res 1997;57:4187-90
-
(1997)
Cancer Res
, vol.57
, pp. 4187-4190
-
-
Rasheed, B.K.1
Stenzel, T.T.2
McLendon, R.E.3
-
22
-
-
2642705040
-
Mutation of the PTEN (MMAC1) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q
-
Bostrom J, Cobbers JM, Wolter M, et al. Mutation of the PTEN (MMAC1) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q. Cancer Res 1998;58:29-33
-
(1998)
Cancer Res
, vol.58
, pp. 29-33
-
-
Bostrom, J.1
Cobbers, J.M.2
Wolter, M.3
-
23
-
-
0032576872
-
PTEN/ MMAC1 mutations in primary glioblastomas and short-term cultures of malignant gliomas
-
Chiariello E, Roz L, Albarosa R, Magnani I, Finocchiaro G. PTEN/ MMAC1 mutations in primary glioblastomas and short-term cultures of malignant gliomas. Oncogene 1998;16:541-45
-
(1998)
Oncogene
, vol.16
, pp. 541-545
-
-
Chiariello, E.1
Roz, L.2
Albarosa, R.3
Magnani, I.4
Finocchiaro, G.5
-
24
-
-
7144223432
-
PTEN mutations in gliomas and glioneuronal tumors
-
Duerr EM, Rollbrocker B, Hayashi Y, et al. PTEN mutations in gliomas and glioneuronal tumors. Oncogene 1998;16:2259-64
-
(1998)
Oncogene
, vol.16
, pp. 2259-2264
-
-
Duerr, E.M.1
Rollbrocker, B.2
Hayashi, Y.3
-
25
-
-
0031892776
-
Microsatellite deletion mapping on chromosome 10q and mutation analysis of MMAC1, FAS, and MXI1 in human glioblastoma multiforme
-
Fults D, Pedone CA, Thompson GE, et al. Microsatellite deletion mapping on chromosome 10q and mutation analysis of MMAC1, FAS, and MXI1 in human glioblastoma multiforme. Int J Oncol 1998;12:905-10
-
(1998)
Int J Oncol
, vol.12
, pp. 905-910
-
-
Fults, D.1
Pedone, C.A.2
Thompson, G.E.3
-
26
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw D, Marsh DJ, Li J, et al. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nature Genet 1997;16:64-67
-
(1997)
Nature Genet
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
-
27
-
-
8544247944
-
Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease
-
Nelen MR, van Staveren WC, Peeters EA, et al. Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease. Hum Mol Genet 1997;6:1383-87
-
(1997)
Hum Mol Genet
, vol.6
, pp. 1383-1387
-
-
Nelen, M.R.1
Van Staveren, W.C.2
Peeters, E.A.3
-
28
-
-
6844252284
-
Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation
-
Marsh DJ, Coulon V, Lunetta KL, et al. Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation. Hum Mol Genet 1998:7:507-15
-
(1998)
Hum Mol Genet
, vol.7
, pp. 507-515
-
-
Marsh, D.J.1
Coulon, V.2
Lunetta, K.L.3
-
30
-
-
13144249184
-
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
-
Suzuki A, de la Pompa JL, Stambolic V, et al. High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice. Curr Biol 1998;8:1169-78
-
(1998)
Curr Biol
, vol.8
, pp. 1169-1178
-
-
Suzuki, A.1
De La Pompa, J.L.2
Stambolic, V.3
-
31
-
-
0030728479
-
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain
-
Furnari FB, Lin H, Huang HS, Cavenee WK. Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain. Proc Natl Acad Sci USA 1997;94:12479-84
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 12479-12484
-
-
Furnari, F.B.1
Lin, H.2
Huang, H.S.3
Cavenee, W.K.4
-
32
-
-
15644369261
-
Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer
-
Cheney IW, Johnson DE, Vaillancourt MT, et al. Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer. Cancer Res 1998;58:2331-34
-
(1998)
Cancer Res
, vol.58
, pp. 2331-2334
-
-
Cheney, I.W.1
Johnson, D.E.2
Vaillancourt, M.T.3
-
33
-
-
0032486198
-
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
-
Tamura M, Gu J, Matsumoto K, Aota S, Parsons R, Yamada KM. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 1998;280:1614-17
-
(1998)
Science
, vol.280
, pp. 1614-1617
-
-
Tamura, M.1
Gu, J.2
Matsumoto, K.3
Aota, S.4
Parsons, R.5
Yamada, K.M.6
-
34
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
Stambolic V, Suzuki A, de la Pompa JL, et al. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 1998;95:29-39
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
De La Pompa, J.L.3
-
36
-
-
0031012306
-
Infrequent methylation of CDKN2A(MTS1/p16) and rare mutation of both CDKN2A and CDKN2B(MTS2/p15) in primary astrocytic tumours
-
Schmidt EE, Ichimura K, Messerle KR, Goike HM, Collins VP. Infrequent methylation of CDKN2A(MTS1/p16) and rare mutation of both CDKN2A and CDKN2B(MTS2/p15) in primary astrocytic tumours. Br J Cancer 1997;75:2-8
-
(1997)
Br J Cancer
, vol.75
, pp. 2-8
-
-
Schmidt, E.E.1
Ichimura, K.2
Messerle, K.R.3
Goike, H.M.4
Collins, V.P.5
-
37
-
-
0031743332
-
Chromosome 7 rearrangements in glioblastomas; loci adjacent to EGFR are independently amplified
-
Liu L, Ichimura K, Pettersson EH, Collins VP. Chromosome 7 rearrangements in glioblastomas; loci adjacent to EGFR are independently amplified. J Neuropathol Exp Neurol 1998;57:1138-45
-
(1998)
J Neuropathol Exp Neurol
, vol.57
, pp. 1138-1145
-
-
Liu, L.1
Ichimura, K.2
Pettersson, E.H.3
Collins, V.P.4
-
38
-
-
0003692572
-
-
World Health Organization. International histological classification of tumors, New York, Springer-Verlag
-
Kleihues P, Burger PC, Scheithauer BW, Histological typing of tumors of the central nervous system., 2nd ed, World Health Organization. International histological classification of tumors, New York, Springer-Verlag, 1993
-
(1993)
Histological Typing of Tumors of the Central Nervous System., 2nd Ed
-
-
Kleihues, P.1
Burger, P.C.2
Scheithauer, B.W.3
-
39
-
-
0020646418
-
Cultured human glial and glioma cells
-
Collins VP. Cultured human glial and glioma cells. Int Rev Exp Pathol 1983;24:135-202
-
(1983)
Int Rev Exp Pathol
, vol.24
, pp. 135-202
-
-
Collins, V.P.1
-
40
-
-
7144251865
-
A highly conserved processed PTEN pseudogene is located on chromosome band 9p21
-
Dahia PLM, FitzGerald MG, Zhang X, et al. A highly conserved processed PTEN pseudogene is located on chromosome band 9p21. Oncogene 1998;16:2403-6
-
(1998)
Oncogene
, vol.16
, pp. 2403-2406
-
-
Dahia, P.L.M.1
FitzGerald, M.G.2
Zhang, X.3
-
42
-
-
0029975476
-
Crystal structure of the dual specificity protein phosphatase VHR
-
Yuvaniyama J, Denu JM, Dixon JE, Saper MA. Crystal structure of the dual specificity protein phosphatase VHR. Science 1996;272: 1328-31
-
(1996)
Science
, vol.272
, pp. 1328-1331
-
-
Yuvaniyama, J.1
Denu, J.M.2
Dixon, J.E.3
Saper, M.A.4
-
43
-
-
3643119742
-
The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G(1) growth arrest in glioma cells
-
Furnari FB, Huang HJS, Cavenee WK. The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G(1) growth arrest in glioma cells. Cancer Res 1998;58:5002-8
-
(1998)
Cancer Res
, vol.58
, pp. 5002-5008
-
-
Furnari, F.B.1
Huang, H.J.S.2
Cavenee, W.K.3
-
44
-
-
0031055324
-
Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases
-
Flint AJ, Tiganis T, Barford D, Tonks NK. Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases. Proc Natl Acad Sci USA 1997;94: 1680-5
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1680-1685
-
-
Flint, A.J.1
Tiganis, T.2
Barford, D.3
Tonks, N.K.4
-
45
-
-
0029739950
-
Control of adhesion-dependent cell survival by focal adhesion kinase
-
Frisch SM, Vuori K, Ruoslahti E, Chan-Hui PY. Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol 1996;134:793-99
-
(1996)
J Cell Biol
, vol.134
, pp. 793-799
-
-
Frisch, S.M.1
Vuori, K.2
Ruoslahti, E.3
Chan-Hui, P.Y.4
-
46
-
-
0032403139
-
Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis
-
Davies MA, Lu YL, Sano T, et al. Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis. Cancer Res 1998;58:5285-90
-
(1998)
Cancer Res
, vol.58
, pp. 5285-5290
-
-
Davies, M.A.1
Lu, Y.L.2
Sano, T.3
-
47
-
-
0032558822
-
Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC
-
Haas-Kogan D, Shalev N, Wong M, Mills G, Yount G, Stokoe D. Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. Curr Biol 1998;8:1195-98
-
(1998)
Curr Biol
, vol.8
, pp. 1195-1198
-
-
Haas-Kogan, D.1
Shalev, N.2
Wong, M.3
Mills, G.4
Yount, G.5
Stokoe, D.6
-
48
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama T, Dixon JE. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 1998;273:13375-78
-
(1998)
J Biol Chem
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
49
-
-
0032506011
-
The lipid phosphatase activity of PTEN is critical for its tumor suppressor function
-
Myers MP, Pass I, Batty IH, et al. The lipid phosphatase activity of PTEN is critical for its tumor suppressor function. Proc Natl Acad Sci USA 1998;95:13513-18
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13513-13518
-
-
Myers, M.P.1
Pass, I.2
Batty, I.H.3
|