Caspases in developmental cell death

IUBMB Life

Volumn 48, Issue 2, 1999, Pages 143-150

  Shearwin Whyatt, Linda M ^a   Kumar, Sharad ^a,b  

^a INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Adaptor; Apoptosis; Caspase activation; Caspases; CED 3

Indexed keywords

CASPASE;

APOPTOSIS; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; NONHUMAN; REVIEW;

ANIMALS; APOPTOSIS; CAENORHABDITIS ELEGANS; CASPASES; DROSOPHILA MELANOGASTER; GENES, HELMINTH; GENES, INSECT; MICE; MUTATION;

EID: 0032748451     PISSN: 15216543     EISSN: None     Source Type: Journal    
DOI: 10.1080/152165499307143     Document Type: Review

References (68)

1. Kerr, J. F. R., Wyllie, A. H., and Currie, A. R. (1972) Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26, 239-257.
2. Wyllie, A. H. (1980) Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284, 555-556.
3. Kumar, S. (1999) Regulation of caspase activation in apoptosis: Implications in pathogenesis and treatment of disease. Clin. Exp. Pharmacol Physiol. 26, 295-303.
4. Cryns, V., and Yuan, J. (1998) Proteases to die for. Genes Dev. 12, 1551-1570.
5. Jacobson, M. D., Weil, M., and Raff, M. C. (1997) Programmed cell death in animal development. Cell 88, 347-354.
6. Vaux, D. L., and Korsmeyer, S. J. (1999) Cell death in development. Cell 96, 245-254.
7. Coucouvanis, E., and Martin, G. R. (1995) Signals for death and survival: A two-step mechanism for cavitation in the vertebrate embryo. Cell 83, 279-287.
8. Zakeri, Z. F., and Ahuja, H. S. (1994) Apoptotic cell death in the limb and its relationship to pattern formation. Biochem. Cell Biol. 72, 603-613.
9. Coles, H. R., Burne, J. F., and Raff, M. C. (1993) Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor. Development 118, 777-784.
10. Wanek, N., Muneoka, K., Holler-Dinsmore, G., Burton, R., and Bryant, S. V. (1989) A staging system for mouse limb development. J. Exp. Zool. 249, 41-49.
11. Ghyselinck, N. B., Dupe, V., Dierich, A., Messaddeq, N., Garnier, J. M., Rochette-Egly, C., Chambon, P., and Mark, M. (1997) Role of the retinoic acid receptor beta (RARβ) during mouse development. Int. J. Dev. Biol 41, 425-447.
12. Dupe, V., Ghyselinck, N. B., Thomazy, V., Nagy, L., Davies, P. J. A., Chambon, P., and Mark, M. (1999) Essential roles of retinoic acid signalling in interdigital apoptosis and control of BMP-7 expression in mouse autopods. Dev. Biol. 208, 30-43.
13. Jiang, C., Baehrecke, E. H., and Thummel, C. S. (1997) Steroid regulated programmed cell death during Drosophila metamorphosis. Development 124, 4673-4683.
14. Yoshizato, K. (1996) Cell death and histolysis in amphibian tail metamorphosis. In Metamorphosis. Postembryonic Reprogramming of Gene Expression in Amphibian and Insect Cells (Gilbert, L. I., Tata, J. R., and Atkinson, B. G., eds.), pp. 647-671, Academic Press, New York.
15. Raff, M. C., Barres, B. A., Burne, J. F., Coles, H. S., Ishizaki, Y., and Jacobson, M. D. (1993) Programmed cell death and the control of cell survival: Lessons from the nervous system. Science 262, 695-700.
16. Cory, S. (1995) Regulation of lymphocyte survival by the bel-2 gene family. Ann. Rev. Immunol. 13, 513-543.
17. Lavin, M. ( 1998) Radiation-induced cell death and its implications in human disease. In Apoptosis: Mechanisms and Role in Disease (Kumar, S., ed.), pp. 213-232, Springer-Verlag, Berlin.
18. Metzstein, M. M., Stanfield, G. M., and Horvitz, H.R. (1998) Genetics of programmed cell death in C. elegans: Past, present and future. Trends Genet. 14, 410-416.
19. Zou, H., Henzel, W. J., Liu, X., Lutschg, A., and Wang, X. (1997) Apaf1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90, 405-413.
20. Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad., M., Alnemri, E. S., and Wang, X. (1997) Cytochrome c and dATP-dependent formation of Apaf1/caspase-9 complex initiates the apoptotic protease cascade. Cell 91, 479-489.
21. Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T., and Alnemri, E. S. (1998) Autoactivation of procaspase-9 by Apaf1-mediated oligomerization. Mol. Cell 1, 949-957.
22. L interacts with Apaf1 and inhibits Apaf1-dependent caspase-9 activation. Proc. Natl. Acad. Sci. USA 95, 4386-4391.
23. Zou, H., Li, Y., Liu, X., and Wang, X. (1999) An Apaf1-cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J. Biol. Chem. 274, 8359-8362.
24. Chinnaiyan, A. M., O'Rourke, K., Tewari, M., and Dixit, V. M. (1995) FADD, a novel death domain-containing protein, interacts with death domain of Fas and initiates apoptosis. Cell 81, 505-512.
25. Adams, J. M., and Cory, S. (1998) The Bcl-2 protein family: Arbiters of cell survival. Science 281, 1322-1326.
26. Kumar, S. (1999) Mechanisms mediating caspase activation in cell death. Cell Death Differ. In press.
27. Rathmel, J. C., and Thompson, C. B. (1999) The central effectors of cell death in the immune system. Annu. Rev. Immunol. 17, 781-828.
28. Nicholson, D. W., and Thornberry, N. A. (1997) Caspases: Killer proteases. Trends Biochem. Sci. 22, 299-306.
29. Colussi, P. A., Harvey, N. L., and Kumar, S. (1998) Prodomain-dependent nuclear localization of the caspase-2(Nedd2) precursor. J. Biol. Chem. 273, 24535-24542.
30. Kumar, S., and Colussi, P. A. (1999) Prodomains - adaptors -oligomerization and the pursuit of caspase activation in apoptosis. Trends Biochem. Sci. 24, 1-4.
31. Ashkenazi, A., and Dixit, V. M. (1998) Death receptors: Signalling and modulation. Science 281, 1305-1308.
32. Green, D. R., and Reed, J.A. (1998) Mitochondria and apoptosis. Science 281, 1309-1312.
33. Gumienny, T. L., Lambie, E., Hartwieg, E., Horvitz, H. R., and Hengartner, M.O. (1999) Gentic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline. Development 126, 1011-1022.
34. Ellis, H. M., and Horvitz, H. R. (1986) Genetic control of programmed cell death in the nematode C. elegans. Cell 44, 817-829.
35. Abrams, J. M., White, K., Fessler, L. I., and Steller, H. (1993) Programmed cell death during Drosophila embryogenesis. Development 117, 29-43.
36. Thummel, C. S. (1996) Flies on steroids - Drosophila metamorphosis and the mechanisms of steroid hormone action. Trends Genet. 12, 306-310.
37. White, K., Grether, M. E., Abrams, J. M., Youmg, L., Farrell, K., and Steller, H. (1994) Genetic control of programmed cell death in Drosophila. Science 264, 677-683.
38. Meier, P., and Evan, G. (1998) Dying like flies. Cell 95, 295-298.
39. Song, Z., McCall, K., and Steller, H. (1997) DCP-1, a Drosophila cell death protease essential for development. Science 275, 536-540.
40. Fraser, A. G., and Evan, G. I. (1997) Identification of a Drosophila melanogaster ICE/CED-3-relaled protease, drICE. EMBO J. 16, 2805-2813.
41. Chen, P., Rodriguez, A., Erskine, R., Thach, T., and Abrams, J. M. (1998) Dredd, a novel effector of the apoptosis activators reaper, grim and hid in Drosophila. Dev. Biol. 201, 202-216.
42. Dorstyn, L., Colussi, P. A., Quinn, L. M., Richardson, H., and Kumar, S. (1999) DRONC, a novel ecdysone-inducible Drosophila caspase. Proc. Natl. Acad. Sci. USA 96, 4307-4312.
43. McCall, K., and Steller, H. (1998) Requirement for DCP-I caspase during Drosophila oogenesis. Science 279, 230-234.
44. Robertson, C. W. (1936) The metamorphosis of Drosophila melanogaster, including an accurately timed account of the principal morphological changes. J. Morphol. 59, 351-399.
45. Bodenstein, D. (1965) The postembryonic development of Drosophila. In Biology of Drosophila (Demerec, M., ed.), pp. 275-367, Hafner Publishing, New York.
46. El Shershaby, A. M., and Hinchliffe, J. R. (1974) Cell redundancy in the zona-intact preimplantation mouse blastocyst: A light and electron microscope study of dead cells and their fate. J. Embryol. Exp. Morphol. 31, 643-654.
47. Glucksman, A. (1951) Cell deaths in normal vertebrate ontogeny. Biol. Rev. 26, 59-86.
48. Kuida, K., Lippke, J. A., Ku, G., Harding, M. W., Livingston, D. J., Su, M. S.-S., and Flavell, R. A. (1995) Altered cytokine export and apoptosis in mice deficient in interleukin-1 β-converting enzyme. Science 267, 2000-2003.
49. Li, P., Allen, H., Banerjee, S., Franklin, S., Herzog, L., Johnston, C., McDowell, J., Paskind, M., Rodman, L., Salfeld, J., Towne, E., Tracey, D., Wardwell, S., Wei, R-Y., Wong, W., Kamen, R., and Seshadri, T. (1995) Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxin shock. Cell 80, 401-411.
50. Wang, S., Miura, M., Bergeron, L., Zhu, H., and Yuan, J. (1998) Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell 92, 501-509.
51. Hakem, R., Hakem, A., Duncan, G. S., Henderson, J. T., Woo, M., Soengas, M. S., Elia, A., de la Pompa, J. L., Kagi, D., Khoo, W., Potter, J., Yoshida, R., Kaufman, S. A., Lowe, S., Penninger, J. M., and Mak, T. W. (1998) Differential requirement for caspase-9 in apoptotic pathways in vivo. Cell 94, 339-352.
52. Fernandes-Alnemri, T., Litwack, G., and Alnemri, E. S. (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein ced-3 and mammalian interleukin-1β-converting enzyme. J. Biol. Chem. 269, 30761-30764.
53. Krajewska, M., Wang, H.-G., Krajewski, S., Zapata, J. M., Shabaik, A., Gascoyne, R., and Reed, J. C. (1997) Immunohistochemical analysis of in vivo patterns of expression of CPP32 (caspase-3), a cell death protease. Cancer Res. 57, 1605-1613.
54. Kuida, K., Haydar, T. F., Kuan, C.-Y., Gu, Y., Taya, C., Karasuyama, H., Su, M. S.-S., Rakic, P., and Flavell, R. A. (1998) Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell 94, 325-337.
55. Kuida, K., Zheng, T. S., Na, S., Kuan, C., Yang, D., Karasuyama, H., Rakic, P., and Flavell, R. A. (1996) Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 384, 368-372.
56. Woo, M., Hakem, R., Soengas, M. S., Duncan, G. S., Shahinian, A., Kagi, D., Hakem, A., McCurrach, M., Khoo, W., Kaufman, S. A., Senaldi, G., Howard, T., Lowe, S. W., and Mak, T. W. (1998) Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes. Genes Dev. 12, 806-819.
57. Varfolomeev, E. E., Schuchmann, M., Luria, V., Chiannilkulchai, N., Beckmann, J. S., Mett, I. L., Rebrikov, D., Brodianski, V. M., Kemper, O. C., Kollet, O., Lapidot, T., Soffer, D., Sobe, T., Avraham, K. B., Goncharov, T., Holtmann, H., Lonai, P., and Wallach, D. (1998) Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apol, and DR3 and is lethal prenatally. Immunity 9, 267-276.
58. Bergeron, L., Perez, G. I., Macdonald, G., Shi, L., Sun, Y., Jurisicova, A., Varmuza, S., Latham, K., Flaws, J., Salter, J. C. M., Hara, H., Moskowitz, M. A., Li, E., Greenberg, M., Tilly, J. L., and Yuan, J. (1998) Defects in regulation of apoptosis in caspase-2-deficient mice. Genes Dev. 12, 1304-1314.
59. Kumar, S., Kinoshita, M., Noda, M., Copeland, N. G., and Jenkins, N. A. (1994) Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1β-converting enzyme. Genes Dev. 8, 1613-1626.
60. Wang, L., Miura, M., Bergeron, L., Zhu, H., and Yuan, J. (1994) Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell 78, 739-750.
61. Kumar, S., Kinoshita, M., Dorstyn, L., and Noda, M. (1997) Origin, expression and possible functions of the two alternatively spliced froms of the mouse Nedd2 mRNA. Cell Death Differ. 4, 378-387.
62. Hengartner, M. O., and Horvitz, H. R. (1994) C. elegans cell death gene ced-9 encodes a functional homolog of mammalian protoncogene bcl-2. Cell 76, 665-676.
63. Cecconi, F., Alvarez-Bolado, G., Meyer, B. I., Roth, K. A., and Gruss, P. (1998) Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell 94, 727-737.
64. Yoshida, H., Kong, Y. Y., Yoshida, R., Elia, A. J., Hakem, A., Hakem, R., Penninger, J. M., and Mak, T. W. (1998) Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell 94, 739-750.
65. Yeh, W. C., de la Pompa, J. L., McCurrach, M. E., Shu, H.-B., Elia, A. J., Shahinian, A., Ng, M., Wakeham, A., Khoo, W., Mitchell, K., El-Deiry, W. S., Lowe, S. W., Goeddel, D. V., and Mak, T. W. (1998) FADD: Essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 279, 1954-1958.
66. Zhang, J., Cado, D., Kabra, N. H., and Winoto, A. (1998) Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/MORT1. Nature 392, 296-299.
67. Newton, K., Harris, A. W., Bath, M. L., Smith, K. G. C., and Strasser, A. (1998) A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J. 17, 706-718.
68. Hu, S., Snipas, S. J., Vincenz, C., Salvesen, G., and Dixit, V. M. (1998) Caspase-14 is a novel developmentally regulated protease. J. Biol. Chem. 273, 29648-29653.