Identification of a Drosophila melanogaster ICE/CED-3-related protease, drICE

EMBO Journal

Volumn 16, Issue 10, 1997, Pages 2805-2813

  Fraser, Andrew G ^a   Evan, Gerard I ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Apoptosis; Caspase; Drosophila melanogaster; ICE; Protease

Indexed keywords

CYCLOHEXIMIDE; CYSTEINE PROTEINASE; ETOPOSIDE; INTERLEUKIN 1BETA CONVERTING ENZYME;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; BACULOVIRUS; CELL DEATH; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GENETIC SCREENING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CAENORHABDITIS ELEGANS PROTEINS; CASPASE 1; CASPASES; CLONING, MOLECULAR; CYSTEINE ENDOPEPTIDASES; DROSOPHILA MELANOGASTER; INHIBITOR OF APOPTOSIS PROTEINS; LAMINS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; VIRAL PROTEINS;

ANIMALIA; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; MELANOGASTER; UNIDENTIFIED BACULOVIRUS; VERTEBRATA;

EID: 0031001092     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.10.2805     Document Type: Article

References (37)

1. Abrams, J.M., White, K., Fessler, L.I. and Steller, H. (1993) Programmed cell death during Drosophila embryogenesis. Development, 117, 29-43.
2. Boldin, M., Goncharov, T., Goltsev, Y. and Wallach, D. (1996) Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell, 85, 803-815.
3. Boldin, M., Varfolomeev, E., Pancer, Z., Mett, I., Camonis, J. and Wallach, D. (1995) A novel protein that interacts with the death domain of Fas/Apol contains a sequence related to the death domain. J. Biol. Chem., 270, 7795-7798.
4. Brown, N.H. and Kafatos, F.C. (1988) Functional cDNA libraries from Drosophila embryos. J. Mol. Biol., 203, 425-437.
5. Bump, N. et al. (1995) Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35. Science, 269, 1885-1888.
6. Cerretti, D.P. et al. (1992) Molecular cloning of the interleukin-1 beta converting enzyme. Science, 256, 97-100.
7. Chen, P., Nordstrom, H., Gish, B. and Abrams, J.M. (1996) grim, a novel cell death gene in Drosophila. Genes Dev., 10, 1773-1782.
8. Chinnaiyan, A.M., O'Rourke, K., Tewari, M. and Dixit, V.M. (1995) FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell, 81, 505-512.
9. Clem, R.J., Fechheimer, M. and Miller, L.K. (1991) Prevention of apoptosis by a baculovirus gene during infection of insect cells. Science, 254, 1388-1390.
10. Ellis, R.E. and Horvitz, H.R. (1991) Two C. elegans genes control the programmed deaths of specific cells in the pharynx. Development, 112, 591-603.
11. Evan, G., Wyllie, A., Gilbert, C., Littlewood, T., Land, H., Brooks, M., Waters, C., Penn, L. and Hancock, D. (1992) Induction of apoptosis in fibroblasts by c-myc protein. Cell, 63, 119-125.
12. Fernandes-Alnemri, T., Litwack, G. and Alnemri, E.S. (1995) Mch2, a new member of the apoptotic ced-3/ICE cysteine protease gene family. Cancer Res., 55, 2737-2742.
13. Fernandes-Alnemri, T., Litwack, G. and Alnemri, E.S. (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J. Biol. Chem., 269, 30761-30764.
14. Fraser, A. and Evan, G. (1996) A license to kill. Cell, 85, 781-784.
15. Fraser, A., McCarthy, N. and Evan, G.I. (1996) Biochemistry of cell death. Curr. Opin. Neurobiol., 6, 71-80.
16. Golstein, P., Marguet, D. and Depraetere, V. (1995) Homology between reaper and the cell death domains of Fas and TNFR1 [letter]. Cell, 81, 185-186.
17. Grether, M.E., Abrams, J.M., Agapite, J., White, K. and Steller, H. (1995) The head involution defective gene of Drosophila melanogaster functions in programmed cell death. Genes Dev., 9, 1694-1708.
18. Gruenbaum, Y., Landesman, Y., Drees, B., Bare, J.W., Saumweber, H., Paddy, M.R., Sedat, J.W., Smith, D.E., Benton, B.M. and Fisher, P.A. (1988) Drosophila nuclear lamin precursor Dm0 is translated from either of two developmentally regulated mRNA species apparently encoded by a single gene. J. Cell Biol., 106, 585-596.
19. Hay, B.A., Wolff, T. and Rubin, G.M. (1994) Expression of baculovirus P35 prevents cell death in Drosophila. Development, 120, 2121-2129.
20. Hengartner, M. and Horvitz, H. (1994) C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell, 76, 665-676.
21. Hengartner, M., Ellis, R.E. and Horvitz, H.R. (1992) Caenorhabditis elegans gene ced-9 protects cells from programmed cell death. Nature, 356, 494-499.
22. Lazebnik, Y., Kaufmann, S., Desnoyers, S., Poirier, G. and Earnshaw, W. (1994) Cleavage of poly(adp-ribose) polymerase by a proteinase with properties like ICE. Nature, 371, 346-347.
23. Muzio, M., Chinnaiyan, A., Kischkel, F., O'Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J., Zhang, M., Gentz, R., Mann, M., Krammer, P., Peter, M. and Dixit, V. (1996) FLICE, a novel FADD homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/Apo-1) death-inducing signaling complex. Cell, 85, 817-827.
24. Nicholson, D., Ali, A., Thornberry, N., Vaillancourt, J., Ding, C., Gallant, M., Gareau, Y., Griffin, P., Labelle, M., Lazebnik, Y., Munday, N., Raju, S., Smulson, M., Yamin, T.-T., Yi, V. and Miller, D. (1995) Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature, 375, 37-43.
25. Pronk, G.J., Ramer, K., Amiri, P. and Williams, L.T. (1996) Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER. Science, 271, 808-810.
26. Raff, M.C. (1992) Social controls on cell survival and cell death. Nature, 356, 397-400.
27. Ray, C.A., Black, S.A., Kronheim, S.R., Greenstreet, T.A., Sleath, P.R., Salvesen, G.S. and Pickup, D.J. (1992) Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme. Cell, 69, 597-604.
28. Rotonda, J., Nicholson, D.W., Fazil, K.M., Gallant, M., Gareau, Y., Labelle, M., Peterson, E.P., Rasper, D.M., Ruel, R., Vaillancourt, J.P., Thornberry, N.A. and Becker, J.W. (1996) The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis. Nature Struct. Biol., 3, 619-625.
29. Slee, E., Zhu, H., Chow, S., MacFarlane, M., Nicholson, D. and Cohen, G. (1996) Benzyloxycarbonyl-Val-Ala-Asp (O-Me) fluoromethylketone (ZVAD.fmk) inhibits apoptosis by blocking the processing of CPP32. Biochem. J., 315, 21-24.
30. Takahashi, A. and Earnshaw, W. (1996) Ice-related proteases in apoptosis. Curr. Opin. Genet. Dev., 6, 50-55.
31. Tewari, M., Quan, L., O'Rourke, K., Desnoyers, S., Zeng, Z., Beidler, D., Poirer, G., Salvesen, G. and Dixit, V. (1995) Yama/CPP32β, a mammalian homolog of CED-3 is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-Ribose) polymerase. Cell, 81, 801-809.
32. Thornberry, N.A. et al. (1992) A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature, 356, 768-774.
33. White, K., Grether, M.E., Abrams, J.M., Young, L., Farrell, K. and Steller, H. (1994) Genetic control of programmed cell death in Drosophila [see comments]. Science, 264, 677-683.
34. White, K., Tahaoglu, E. and Steller, H. (1996) Cell killing by the Drosophila gene reaper. Science, 271, 805-807.
35. Xue, D. and Horvitz, H.R. (1995) Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein. Nature, 377, 248-251.
36. Yuan, J. and Horvitz, H.R. (1992) The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death. Development, 116, 309-320.
37. Yuan, J., Shaham, S., Ledoux, S., Ellis, H.M. and Horvitz, H.R. (1993) The C. elegans cell-death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta converting enzyme. Cell, 75, 641-652.