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Volumn 3, Issue 6, 1999, Pages 681-687

Bioinspired polymeric materials: In-between proteins and plastics

Author keywords

[No Author keywords available]

Indexed keywords

BIOMATERIAL; OLIGOMER; PLASTIC; POLYMER; PROTEIN;

EID: 0032705431     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(99)00026-5     Document Type: Review
Times cited : (194)

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    • 2-OH
    • A γ-peptide hexamer containing valine, alanine and leucine sidechains was studied and compared with the corresponding α-peptides and β-peptides. A stable secondary structure for the γ-peptide is characterized by two-dimensional NMR spectroscopy in organic solvents. A right-handed helical structure is described with a pitch of 5 Å, and defined by the formation of 14-membered hydrogen-bonded rings along the backbone
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    • Sequence-specific N-substituted glycine polymers (peptoids) up to 36 residues in length were synthesized using a robotic solid-phase protocol. A diverse set of chiral sidechains were incorporated, including aliphatic, aromatic, heterocyclic, cationic and anionic groups. CD spectra indicative of helical secondary structures are observed in both aqueous and organic solvents at temperatures up to 65°C. This structure is stable at short chain lengths (5 residues), despite the inability of these molecules to form backbone hydrogen bonds
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.