Dual effect of CCR5 Δ32 gene deletion in HIV-1-infected patients [2]

Lancet

Volumn 349, Issue 9069, 1996, Pages 1884-

  Garred, Peter ^a   Eugen Olsen, Jesper ^b   Iversen, Astrid K N ^b   Benfield, Thomas L ^b   Svejgaard, Arne ^b   Hofmann, Bo ^b   Koppelhus, Uffe ^b   Pedersen, Court ^b   Sørensen, Anne M ^b   Katzenstein, Terese ^b   Gerstoft, Jan ^b   Skinhøj, Peter ^b   Nielsen, Jens O ^b   Dickmeiss, Ebbe ^b  

^a University of Copenhagen   (Denmark)

^b HVIDOVRE HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR; VIRUS RECEPTOR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; GENE DELETION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LETTER; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; RECEPTOR GENE; SURVIVAL TIME;

EID: 0030604565     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(05)63874-3     Document Type: Article

References (5)

1. 1 Samson M, Libert F, Doranz BJ, et al. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996; 382: 722-25.
2. 2 Liu R, Paxton WA, Choe S, et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996; 86: 367-77.
3. 3 Dean M, Carrington M, Winkler C, et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Science 1996; 273: 1856-62.
4. 4 Michael NL, Chang G, Louie LG, et al. The role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease progression. Nat Med 1997; 3: 338-40.
5. 5 Eugen-Olsen J, Iversen AKN, Garred P, et al. Heterozygosity for a deletion in the CKR-5 gene leads to prolonged AIDS free survival and slower CD4T cell fall in a cohort followed for 11 years. AIDS 1997; 11: 305-10.