Melatonin maintains glutathione homeostasis in kainic acid-exposed rat brain tissues

FASEB Journal

Volumn 11, Issue 14, 1997, Pages 1309-1315

  Floreani, Maura ^a   Skaper, Stephen D ^a   Facci, Laura ^a   Lipartiti, Maria ^a   Giusti, Pietro ^a,b  

^a UNIVERSITY OF PADOVA   (Italy)

^b Department of Pharmacology ^*  (Italy)

Author keywords

Glutathione peroxidase; Glutathione reductase; GSH; Neuroprotection; Oxidative stress; ROS

Indexed keywords

GLUTATHIONE; GLUTATHIONE REDUCTASE; KAINIC ACID; KAINIC ACID RECEPTOR; MELATONIN; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL TISSUE; BRAIN; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; HOMEOSTASIS; MALE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0030693112     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.11.14.9409550     Document Type: Conference Paper

References (52)

1. Sperk, G. (1994) Kainic acid seizures in the rat. Prog. Neurobiol. 42, 1-32
2. Olney, J. W., Rhee, V., and Ho, O. L. (1974) Kainic acid: a powerful toxic analogue of glutamate. Brain Res. 77, 507-512
3. Coyle, J. T., and Puttfarcken, P. (1993) Oxidative stress, glutamate, and neurodegenerative disorders. Science 262, 689-693
4. Puttfarcken, P. S., Getz, R. L., and Coyle, J. T. (1993) Kainic acid-induced lipid peroxidation: Protection with butylated hydroxytoluene and U78517F in primary cultures of cerebellar granule cells. Brain Res. 624, 223-232
5. Giusti, P., Gusella, M., Lipartiti, M., Milani, D., Zhu, W., Vicini, S., and Manev, H. (1995) Melatonin protects primary cultures of cerebellar granule neurons from kainate but not from N-methyl-D-aspartate excitotoxicity. Exp. Neurol. 131, 39-46
6. Giusti, P., Lipartiti, M., Franceschini, D., Schiavo, N., Floreani, M., and Manev, H. (1996) Neuroprotection by melatonin from kainate-induced excitotoxicity in rats. FASEB J. 10, 891-896
7. Giusti, P., Franceschini, D., Petrone, M., Manev, H., and Floreani, M. (1996) In vivo and in vitro protection against kainate-induced excitotoxicity by melatonin. J. Pineal Res. 20, 226-231
8. Tan, D.-Z., Chen, L.-D., Poeggeler, B., Manchester, L. C., and Reiter, R. J. (1993) Melatonin: a potent, endogenous hydroxyl radical scavenger. Endocrine J. 1, 57-60
9. Matuszak, Z., Reszka, K., and Chignell, G. F. (1997) Reaction of melatonin and related indoles with hydroxyl radicals: EPR and spin trapping investigations. Free Rad. Biol. Med. 23, 367-372
10. Pieri, C., Marra, M., Moroni, F., Recchioni, R., and Marcheselli, F. (1994) Melatonin: A peroxyl radical scavenger more effective than vitamin E. Life Sci. 55, PL271-PL276
11. Cagnoli, C. M., Atabay, C., Kharlamov, E., and Manev, H. (1995) Melatonin protects neurons from singlet oxygen-induced apoptosis. J Pineal Res. 18, 222-226
12. Melchiorri, D., Reiter, R. J., Sewerynek, E., Hara, M., Chen, L. D., and Nisticò, G. (1996) Paraquat toxicity and oxidative damage: Reduction by melatonin. Biochem. Pharmacol. 51, 1095-1099
13. Reiter, R. J. (1995) Oxidative processes and antioxidative defense mechanisms in the aging brain. FASEB J. 9, 526-533
14. Phillis, J. W. (1994) A "radical" view of cerebral ischemic injury. Prog. Neurobiol. 42, 441-448
15. Meister, A. (1995) Strategies for increasing cellular glutathione. In Biothiols in Health and Disease (Packer, L., and Cardenas, E., eds) pp. 165-188, Dekker, New York
16. Meister, A., and Anderson, M. E. (1983) Glutathione. Annu. Rev. Biochem. 52, 711-760
17. Anderson, M. E. (1985) Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol. 113, 548-555
18. Tietze, F. (1969) Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 27, 502-522
19. Floreani, M., Petrone, M., Debetto, P., and Palatini, P. (1997) A comparison between different methods for the determinations of reduced and oxidized glutathione in mammalian tissues. Free Radical Res. 26, 449-455
20. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. (1951) Protein measurement with Folin phenol reagent. J. Biol. Chem. 193, 265-275
21. Prohaska, J. R, and Ganther, H. E. (1976) Selenium and glutathione peroxidase in developing rat brain. J. Neurochem. 27, 1379-1387
22. Carlberg, I., and Mannervik, B. (1975) Purification and characterization of the flavoenzyme glutathione-reductase from rat liver. J. Biol. Chem. 250, 5475-5480
23. Skaper, S. D., Facci, L., Milani, D., Leon, A., and Toffano, G. (1990) Culture and use of primary and clonal neural cells. In Methods in Neurosciences, Vol. 2 (Conn, P. M., ed) pp. 17-33, Academic Press, San Diego
24. Dykens, J. A., Stern, A., and Trenkner, E. (1987) Mechanism of kainate toxicity to cerebellar neurons in vitro is analogous to reperfusion tissue injury. J. Neurochem. 49, 1222-1228
25. Nicoletti, F., Wroblewski, J. T., Novelli, A., Alho, H., Guidotti, A., and Costa, E. (1986). The activation of inositol phospholipid metabolism as a signal-transducing system for excitatory amino acids in primary cultures of cerebellar granule cells. J. Neurosci. 6, 1905-1911
26. McCaslin, P. P., and Morgan, W. W. (1987) Cultured cerebellar cells as an in vitro model of excitatory amino acid receptor function. Brain Res. 417, 380-384
27. Milani, D., Facci, L., Guidolin, D., Leon, A., and Skaper, S. D. (1989) Activation of polyphosphoinositide metabolism as a signal-transducing system coupled to excitatory amino acid receptors in astroglial cells. Glia 2, 161-169
28. Kato, K., Puttfarcken, P. S., Lyons, W. E., and Coyle, J. T. (1991) Developmental time course and ionic dependence of kainate-mediated toxicity in rat cerebellar granule cell cultures. J. Pharmacol. Exp. Ther. 256, 402-411
29. Bondy, S. C., and Lee, D. K. (1993) Oxidative stress induced by glutamate receptor agonists. Brain Res. 610, 229-233
30. Cheng, Y., and Sun, A. Y. (1994) Oxidative mechanisms involved in kainate-induced cytotoxicity in cortical neurons. Neurochem. Res. 19, 1557-1564
31. Uz, T., Kharlamov, A., Joo, J.-Y, Franceschini, D., Giusti, P., and Manev, H. (1997) Kainate-induced DNA damage and p53 immunoreactivity in the rat hippocampus: protection with melatonin. Croatian Med. J. 38, 205-211
32. Manev, H., Kharlamov, A., and Armstrong, D. M. (1994) Photochemical brain injury in rats triggers DNA fragmentation, p53, and HS72. Neuroreport 5, 2661-2664
33. Manev, H., Cagnoli, C. M., Kharlamov, A., Atabay, C., and Kharlamov, E. (1995) In vitro and in vivo neuroprotection with melatonin against toxicity of singlet oxygen. Soc. Neurosci. Abstr. 21, 1518
34. Melchiorri, D., Reiter, R. J., Sewerynek, E., Chen, L. D., and Nisticò, G. (1995) Melatonin reduces kainate-induced lipid perox- idation in homogenates of different brain regions. FASEB J. 9, 1205-1210
35. 2-induced lipid peroxidation in homogenates of different brain regions. J. Pineal. Res. 19, 51-56
36. Sewerynek, E., Reiter, R. J., Melchiorri, D., Ortiz, G. G., and Lewinski, A. (1996) Oxidative damage in the liver induced by ischemia-reperfusion: protection by melatonin. Hepatogastroenterology 43, 898-905
37. Cooper, A. J. L., and Meister, A. (1993) Glutathione in the brain: disorders of glutathione metabolism. In The Molecular and Genetic Basis of Neurological Disease (Rosenberg, R., Prusiner, S., Di Mauro, S., Barchi, R., and Kunkel, L., eds) pp. 209-238, Butter-worths, Stoneham, Massachusetts
38. Jain, A., Mãrtensson, J., Stole, E., Auld, P. A. M., and Meister, A. (1995) Glutathione deficiency leads to mitochondrial damage in brain. Proc. Natl. Acad. Sci. USA 88, 1913-1917
39. Sun, A. Y., Cheng, Y., Bu, Q., and Oldfield, F. (1992) The biochemical mechanisms of the excitotoxicity of kainic acid. Mol. Chem. Neuropathol. 17, 51-63
40. Huang, J., and Philbert, M. A. (1996) Cellular responses of cultured cerebellar astrocytes to ethacrynic acid-induced perturbation of subcellular glutathione homeostasis. Brain Res. 711, 184-192
41. Pigcolet, E., and Remacle, J. (1991) Susceptibility of glutathione peroxidase to proteolysis after oxidative alterations by peroxides and hydroxyl radicals. Free Radical Biol. Med. 11, 191-195
42. Barlow-Walden, L. R., Reiter, R. J., Abe, M., Pablos, M. I., Menendez-Pelaez, A., Chen, L.-D., and Poeggeler, B. (1995) Melatonin stimulates brain glutathione peroxidase activity. Neurochem. Int. 26, 497-502
43. Antolin, I., Rodriguez, C., Sainz, R. M., Mayo, J. C., Uria, H., Kotler, M. L., Rodriguez-Colunga, M. J., Tolivia, D., and Menendez-Pelaez, A. (1996) Neurohormone melatonin prevents cell damage: effect on gene expression for antioxidant enzymes. FASEB J. 10, 882-890
44. Bazan, N. G., Birckle, D.L, Tang, W., and Reddy, D. S. (1986) The accumulation of free arachidonic acid, diacylglycerols, prostaglandins, and lipoxygenase reaction products in the brain during experimental epilepsy. In Basic Mechanisms of the Epilepsies: Advances in Neurology (Delgado-Escueta, A. V., Ward, A. A., Woodbury, D. M., and Porter, R. J., eds) Vol. 44, pp. 385-394, Raven Press, New York
45. Manev, H., Uz, T., Kharlamov, A., and Joo, J. Y. (1996) Increased brain damage after stroke or excitotoxic seizures in melatonin-dericient rats. FASEB J. 10, 1546-1551
46. Saija, A., Princi, P., Pisani, A., Lanza, M., Scalese, M., Aramnejad, E., Cesarani, R., and Costa, G. (1997) Protective effect of glutathione on kainic acid-induced neuropathological changes in rat brain. Gen. Pharmacol. 25, 97-102
47. Chuang, J., and Lin, M. T. (1994) Pharmacological effects of melatonin treatment on both locomotor activity and brain serotonin release in rats. J Pineal. Res. 17, 11-16
48. Norlund, J. J., and Lerner, A. B. (1977) The effects of oral melatonin on skin color and on the release of pituitary hormones. J. Clin. Endocrinol. Metab. 45, 768-774
49. 11C]melatonin in humans. Nucl. Med. Biol. 18, 357-362
50. Menendez-Pelaez, A., Poeggeler, B., Reiter, R. J., Barlow-Walden, L. R., Pablos, M. I., and Tan, D. X. (1993) Nuclear localization of melatonin in different mammalian tissues: immunocytochemical and radioimmunoassay evidence. J. Cell. Biochem. 53, 373-382
51. Olanow, C. W. (1992) An introduction to the free radical hypothesis in Parkinson's disease. Ann. Neurol. 32, 52-59
52. Halliwell, B. (1992) Reactive oxygen species and the central nervous system. J. Neurochem. 59, 1609-1623