Melatonin affords protection against kainate-induced in vitro lipid peroxidation in brain

European Journal of Pharmacology

Volumn 305, Issue 1-3, 1996, Pages 239-242

  Melchiorri, Daniela ^a,b   Reiter, Russel J ^a   Chen, Li Dun ^a   Sewerynek, Ewa ^a   Nisticò, Giuseppe ^b  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF ROME   (Italy)

Author keywords

brain; kainate; lipid peroxidation; melatonin; rat

Indexed keywords

4 HYDROXYALKENAL; KAINIC ACID; MALONALDEHYDE; MELATONIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTECTION; RAT; TISSUE HOMOGENATE;

EID: 0030000079     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00241-5     Document Type: Article

References (15)

1. Bondy, S.C. and D.K. Lee, 1993, Oxidative stress induced by glutamate receptor agonists, Brain Res. 610, 229.
2. Bose, R., L. Schnell, C. Pinsky and V. Zitko, 1992, Effects of excitotoxins on free radical indices in mouse brain, Toxicol. Lett. 60, 211.
3. Coyle, J.T., 1983, Neurotoxic action of kainic acid. Short review, J. Neurochem. 41,1.
4. Dykens, J.A., A. Stern and E. Trenkner, 1987, Mechanism of kainate toxicity to cerebellar neurons in vitro is analogous to reperfusion tissue injury, J. Neurochem. 409, 1222.
5. Esterbauer, H. and K.H. Cheeseman, 1990, Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal, Methods Enzymol. 186, 407.
6. Ferkany, J.W. and J.T. Coyle, 1983, Kainic acid selectively stimulates the release of endogenous excitatory acidic aminoacids, J. Pharmacol. Exp. Ther. 225, 399.
7. Ikeda, Y. and D.L. Long, 1990, The molecular basis of brain injury and brain edema: the role of oxygen free radicals, Neurosurgery 27, 1.
8. Melchiorri, D., R.J. Reiter, A. Attia, M. Hara, A. Burgos and G. Nisticò, 1995, Potent protective effect of melatonin on in vivo paraquat induced toxicity, Life Sci. 56, 83.
9. Miyamoto, M., T.H. Murphy, R.L. Schaar and J. Coyle, 1989, Antioxidants protect against glutamate-induced cytotoxycity in a neuronal cell line, J. Pharmacol. Exp. Ther. 250, 1132.
10. Reiter, R.J., D.-X. Tan, B. Poeggeler, A. Menendez-Pelaez, L.-D. Chen and S. Saarela, 1994, Melatonin as a free radical scavenger: implication for aging and age-related diseases, Ann. N.Y. Acad. Sci. 719, 1.
11. Reiter, R.J., D. Melchiorri, E. Sewerynek, B. Poeggeler, L.R. Barlow-Walden, J. Chuang, G.G. Ortiz and D. Acuna-Castroviejo, 1995, A review of the evidence supporting melatonin's role as an antioxidant, J. Pineal Res. 18, 1.
12. Sewerynek, E., D. Melchiorri, L.D. Chen and R.J. Reiter, 1995, Melatonin reduces both basal and bacterial lipopolysaccharide-induced lipid peroxidation in vitro, Free Rad. Biol. Med. 19, 903.
13. Sun, A.Y., Y. Cheng, Q. Bu and F. Oldfield, 1992, The biochemical mechanism of the excytotoxicity of kainic acid, Mol. Chem. Neuropathol. 17, 51.
14. Willmore, L.J. and W.J. Triggs, 1984, Effects of phenytoin and corticosteroids on seizures and lipid peroxidation in experimental posttraumatic epilepsy, J. Neurosurg. 60, 467.
15. Voordouw, B.C.G., R. Eusner, R.E.R. Verdonk, B.T.H. Alberda, F.H. De Jong, A.C. Drogendijk, B.C.J.M. Fauser and M. Cohen, 1992, Melatonin and melatonin-progestin combinations alter pituary-ovarian function in women and can inhibit ovulation, J. Clin. Endocrinol. Metab. 74, 108.