-
1
-
-
0026748342
-
Growth factors affecting human thrombocytopoiesis: Potential agents for the treatment of thrombocytopenia
-
Gordon MS, Hoffman R, Growth factors affecting human thrombocytopoiesis: potential agents for the treatment of thrombocytopenia. Blood (1992) 80: 302-7.
-
(1992)
Blood
, vol.80
, pp. 302-307
-
-
Gordon, M.S.1
Hoffman, R.2
-
2
-
-
0000009286
-
Demonstration and some properties of human thrombopoietin in thrombocytopenic sera
-
Keleman E, Cserhati I, Tanos B, Demonstration and some properties of human thrombopoietin in thrombocytopenic sera. Acta Haematol (1958) 20: 350-3.
-
(1958)
Acta Haematol
, vol.20
, pp. 350-353
-
-
Keleman, E.1
Cserhati, I.2
Tanos, B.3
-
3
-
-
0014575527
-
Measurement of thrombopoiesis in rabbits using selenomethionine
-
Evatt BL, Levin J, Measurement of thrombopoiesis in rabbits using selenomethionine J Clin Invest (1969) 48: 1615-26.
-
(1969)
J Clin Invest
, vol.48
, pp. 1615-1626
-
-
Evatt, B.L.1
Levin, J.2
-
4
-
-
84967902511
-
Isotope bioassay for 'thrombopoietin'
-
Penington DG, Isotope bioassay for 'thrombopoietin'. Br Med J (1970) i: 606-8.
-
(1970)
Br Med J
, vol.1
, pp. 606-608
-
-
Penington, D.G.1
-
5
-
-
0020086543
-
Immature megakaryocytes in the mouse: Physical characteristics, cell cycle status, and in vitro responsiveness to thrombopoietic stimulatory factor
-
Long MW, Williams N, Ebbe S, Immature megakaryocytes in the mouse: physical characteristics, cell cycle status, and in vitro responsiveness to thrombopoietic stimulatory factor. Blood (1982) 59: 569-75.
-
(1982)
Blood
, vol.59
, pp. 569-575
-
-
Long, M.W.1
Williams, N.2
Ebbe, S.3
-
6
-
-
0023179211
-
Megakaryocyte morphogenesis stimulated in vitro by whole and partially fractionated thrombocytopenic plasma. a model system for the study of platelet formation
-
Leven RM, Yee MK, Megakaryocyte morphogenesis stimulated in vitro by whole and partially fractionated thrombocytopenic plasma. a model system for the study of platelet formation. Blood (1987) 69: 1046-52.
-
(1987)
Blood
, vol.69
, pp. 1046-1052
-
-
Leven, R.M.1
Yee, M.K.2
-
7
-
-
0024450006
-
The effect of partially purified thrombopoietin on guinea pig megakaryocyte ploidy in vitro
-
Hill RJ, Leven RM, Levin FC, Leven J, The effect of partially purified thrombopoietin on guinea pig megakaryocyte ploidy in vitro. Exp Hematol (1989) 17: 903-7.
-
(1989)
Exp Hematol
, vol.17
, pp. 903-907
-
-
Hill, R.J.1
Leven, R.M.2
Levin, F.C.3
Leven, J.4
-
8
-
-
0022624954
-
MPLV: A retrovirus complex inducing an acute myeloproliferative leukemic disorder in adult mice
-
Wendling F, Varlet P, Charon M, Tambourin P, MPLV: a retrovirus complex inducing an acute myeloproliferative leukemic disorder in adult mice. Virology (1986) 149: 242-6.
-
(1986)
Virology
, vol.149
, pp. 242-246
-
-
Wendling, F.1
Varlet, P.2
Charon, M.3
Tambourin, P.4
-
9
-
-
0024580738
-
Factor-independent erythropoietic progenitor cells in leukemia induced by the myeloproliferative leukemia virus
-
Wendling F, Penciolelli J-F, Charon M, Tambourin P, Factor-independent erythropoietic progenitor cells in leukemia induced by the myeloproliferative leukemia virus. Blood (1989) 73: 1161-7.
-
(1989)
Blood
, vol.73
, pp. 1161-1167
-
-
Wendling, F.1
Penciolelli, J.-F.2
Charon, M.3
Tambourin, P.4
-
10
-
-
0024403304
-
Myeloid progenitor cells transformed by the myeloproliferative leukemia virus proliferate and differentiate in vitro without the addition of growth factors
-
Wendling F, Vigon I, Souyri M, Tambourin P, Myeloid progenitor cells transformed by the myeloproliferative leukemia virus proliferate and differentiate in vitro without the addition of growth factors. Leukemia (1989) 3: 475-80.
-
(1989)
Leukemia
, vol.3
, pp. 475-480
-
-
Wendling, F.1
Vigon, I.2
Souyri, M.3
Tambourin, P.4
-
11
-
-
0025674093
-
A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors
-
Souyri M, Vigon I, Penciolelli J-F et al, A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors. Cell (1990) 63: 1137-4-7.
-
(1990)
Cell
, vol.63
, pp. 1137-1147
-
-
Souyri, M.1
Vigon, I.2
Penciolelli, J.-F.3
-
12
-
-
0027225872
-
Oligodeoxynucleotides antisense to the proto-oncogene c-mpl specifically inhibit in vitro megakaryocytopoiesis
-
Methia N, Louache F, Vainchenker W, Wendling F, Oligodeoxynucleotides antisense to the proto-oncogene c-mpl specifically inhibit in vitro megakaryocytopoiesis. Blood (1993) 82: 1395-401.
-
(1993)
Blood
, vol.82
, pp. 1395-1401
-
-
Methia, N.1
Louache, F.2
Vainchenker, W.3
Wendling, F.4
-
13
-
-
0028343099
-
Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl
-
Bartley TD, Bogenberger J, Hunt P et al, Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. Cell (1994) 77: 1117-24.
-
(1994)
Cell
, vol.77
, pp. 1117-1124
-
-
Bartley, T.D.1
Bogenberger, J.2
Hunt, P.3
-
14
-
-
0028302409
-
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand
-
DeSauvage FJ, Hass PE, Spencer SD et al, Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature (1994) 369: 533-8.
-
(1994)
Nature
, vol.369
, pp. 533-538
-
-
Desauvage, F.J.1
Hass, P.E.2
Spencer, S.D.3
-
15
-
-
0028199208
-
Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo
-
Lok S, Kaushansky K, Holly RD et al, Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature (1994) 369: 565-8.
-
(1994)
Nature
, vol.369
, pp. 565-568
-
-
Lok, S.1
Kaushansky, K.2
Holly, R.D.3
-
16
-
-
0027992924
-
Molecular cloning and chromosomal localisation of the human thrombopoietin gene
-
Sohma Y, Akahori H, Seki N et al, Molecular cloning and chromosomal localisation of the human thrombopoietin gene. FEBS Lett (1994) 353: 57-61.
-
(1994)
FEBS Lett
, vol.353
, pp. 57-61
-
-
Sohma, Y.1
Akahori, H.2
Seki, N.3
-
17
-
-
0028557354
-
Human thrombopoietin gene structure, cDNA sequence, expression and chromosomal localization
-
Foster DC, Sprecher CA, Grant FJ et al, Human thrombopoietin gene structure, cDNA sequence, expression and chromosomal localization. Proc Natl Acad Sci USA (1994) 91: 13 023-7.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 13023-13027
-
-
Foster, D.C.1
Sprecher, C.A.2
Grant, F.J.3
-
18
-
-
0029007758
-
The gene for murine megakaryocyte growth and development factor (thrombopoietin, Thpo) is located on mouse chromosome 16
-
Chang M-S, Hsu R-Y, McNinch J et al, The gene for murine megakaryocyte growth and development factor (thrombopoietin, Thpo) is located on mouse chromosome 16. Genomics (1995) 26: 636-7.
-
(1995)
Genomics
, vol.26
, pp. 636-637
-
-
Chang, M.-S.1
Hsu, R.-Y.2
McNinch, J.3
-
19
-
-
0028892286
-
Murine thrombopoietin mRNA levels are modulated by platelet count
-
McCarty JM, Sprugel KH, Fox NE et al, Murine thrombopoietin mRNA levels are modulated by platelet count. Blood (1995) 86: 3668-75.
-
(1995)
Blood
, vol.86
, pp. 3668-3675
-
-
McCarty, J.M.1
Sprugel, K.H.2
Fox, N.E.3
-
20
-
-
0030048887
-
Thrombopoietin in thrombocytopenic mice: Evidence against regulation at the mRNA level and for a direct regulatory role of platelets
-
Stoffel R, Wiestner A, Skoda RC, Thrombopoietin in thrombocytopenic mice: evidence against regulation at the mRNA level and for a direct regulatory role of platelets Blood (1996) 87: 567-73.
-
(1996)
Blood
, vol.87
, pp. 567-573
-
-
Stoffel, R.1
Wiestner, A.2
Skoda, R.C.3
-
21
-
-
0031035555
-
Localization and regulation of thrombopoietin mRNA expression in human kidney, liver, bone marrow, and spleen using in situ hybridization
-
Sungaran R, Markovic B, Chong BH, Localization and regulation of thrombopoietin mRNA expression in human kidney, liver, bone marrow, and spleen using in situ hybridization. Blood (1996) 89: 101-7.
-
(1996)
Blood
, vol.89
, pp. 101-107
-
-
Sungaran, R.1
Markovic, B.2
Chong, B.H.3
-
22
-
-
0030020395
-
Bone marrow stromal cells produce thrombopoietin and stimulate megakaryocyte growth and maturation but suppress proplatelet formation
-
Nagahisa H, Nagata Y, Ohnuki T et al, Bone marrow stromal cells produce thrombopoietin and stimulate megakaryocyte growth and maturation but suppress proplatelet formation. Blood (1996) 87: 1309-16.
-
(1996)
Blood
, vol.87
, pp. 1309-1316
-
-
Nagahisa, H.1
Nagata, Y.2
Ohnuki, T.3
-
23
-
-
0029148579
-
Purification and characterization of thrombopoietin
-
Kato T, Ogami K, Shimada Y et al, Purification and characterization of thrombopoietin. J Biochem (1995) 118: 229-36.
-
(1995)
J Biochem
, vol.118
, pp. 229-236
-
-
Kato, T.1
Ogami, K.2
Shimada, Y.3
-
24
-
-
0029035989
-
Purification and biologic characterization of plasma-derived megakaryocyte growth and development factor
-
Hunt P, Li YS, Nichol JL, Purification and biologic characterization of plasma-derived megakaryocyte growth and development factor. Blood (1995) 86: 540-7.
-
(1995)
Blood
, vol.86
, pp. 540-547
-
-
Hunt, P.1
Li, Y.S.2
Nichol, J.L.3
-
25
-
-
0028809982
-
The physiologic role and therapeutic potential of the Mpl-ligand in thrombopoiesis
-
Hunt P, The physiologic role and therapeutic potential of the Mpl-ligand in thrombopoiesis. Stem Cells (1995) 13: 579-87.
-
(1995)
Stem Cells
, vol.13
, pp. 579-587
-
-
Hunt, P.1
-
26
-
-
12644303248
-
Thrombin cleaves human thrombopoietin: One of the proteolytic events that generates truncated forms of thrombopoietin
-
Kato T, Oda A, Ingake Y et al, Thrombin cleaves human thrombopoietin: one of the proteolytic events that generates truncated forms of thrombopoietin. Proc Natl Acad Sci USA (1997) 94: 4669-74.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4669-4674
-
-
Kato, T.1
Oda, A.2
Ingake, Y.3
-
27
-
-
0028086542
-
Thrombocytopenia in c-mpl-deficient mice
-
Gurney AL, Carver-Moore K, deSauvage FJ, Moore MW, Thrombocytopenia in c-mpl-deficient mice. Science (1994) 265: 1445-7.
-
(1994)
Science
, vol.265
, pp. 1445-1447
-
-
Gurney, A.L.1
Carver-Moore, K.2
DeSauvage, F.J.3
Moore, M.W.4
-
28
-
-
0029046966
-
Megakaryocyte growth and development factor. Analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy-induced thrombocytopenia
-
Nichol JL, Hokom MM, Hornkohl A et al, Megakaryocyte growth and development factor. Analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy-induced thrombocytopenia. J Clin Invest (1995) 95: 2973-8.
-
(1995)
J Clin Invest
, vol.95
, pp. 2973-2978
-
-
Nichol, J.L.1
Hokom, M.M.2
Hornkohl, A.3
-
29
-
-
0029744304
-
Serum thrombopoietin level in various hematological diseases
-
Usuki K, Tahara T, Iki S et al, Serum thrombopoietin level in various hematological diseases. Stem Cells (1996) 14: 558-65.
-
(1996)
Stem Cells
, vol.14
, pp. 558-565
-
-
Usuki, K.1
Tahara, T.2
Iki, S.3
-
30
-
-
0030968519
-
Human platelets display high-affinity receptors for thrombopoietin
-
Broudy VC, Lin NL, Sabath DF et al, Human platelets display high-affinity receptors for thrombopoietin. Blood (1997) 89: 1896-904.
-
(1997)
Blood
, vol.89
, pp. 1896-1904
-
-
Broudy, V.C.1
Lin, N.L.2
Sabath, D.F.3
-
31
-
-
0030901558
-
Human platelets as a model for the binding and degradation of thrombopoietin
-
Fielder PJ, Hass P, Nagel M et al, Human platelets as a model for the binding and degradation of thrombopoietin. Blood (1997) 89: 2782-8.
-
(1997)
Blood
, vol.89
, pp. 2782-2788
-
-
Fielder, P.J.1
Hass, P.2
Nagel, M.3
-
32
-
-
0029865443
-
Regulation of thrombopoietin levels by c-mpl-mediated binding to platelets
-
Fielder PJ, Gurney AL, Stefanich E et al, Regulation of thrombopoietin levels by c-mpl-mediated binding to platelets. Blood (1996) 87: 2154-61.
-
(1996)
Blood
, vol.87
, pp. 2154-2161
-
-
Fielder, P.J.1
Gurney, A.L.2
Stefanich, E.3
-
33
-
-
0029858508
-
Differential mechanisms in the regulation of endogenous levels of thrombopoietin and interleukin-11 during thrombocytopenia: Insight into the regulation of platelet production
-
Chang M, Suen Y, Meng G et al, Differential mechanisms in the regulation of endogenous levels of thrombopoietin and interleukin-11 during thrombocytopenia: insight into the regulation of platelet production. Blood (1996) 88: 3354-62.
-
(1996)
Blood
, vol.88
, pp. 3354-3362
-
-
Chang, M.1
Suen, Y.2
Meng, G.3
-
34
-
-
0029051295
-
Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development
-
Shivdasani RA, Rosenblatt MF, Zucker-Franklin D et al, Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development. Cell (1995) 81: 695-704.
-
(1995)
Cell
, vol.81
, pp. 695-704
-
-
Shivdasani, R.A.1
Rosenblatt, M.F.2
Zucker-Franklin, D.3
-
35
-
-
0030970642
-
Metabolism of thrombopoietin (TPO) in vivo: Determination of the binding dynamics for TPO in mice
-
Stefanich E, Senn T, Widmer R et al, Metabolism of thrombopoietin (TPO) in vivo: determination of the binding dynamics for TPO in mice. Blood (1997) 89: 4063-70.
-
(1997)
Blood
, vol.89
, pp. 4063-4070
-
-
Stefanich, E.1
Senn, T.2
Widmer, R.3
-
36
-
-
0028909690
-
Thrombopoietin (c-mpl ligand) acts synergistically with erythropoietin, stem cell factor, and interleukin-11 to enhance megakaryocyte colony growth and increases megakaryocyte ploidy in vitro
-
Broudy VC, Lin NL, Kaushansky K, Thrombopoietin (c-mpl ligand) acts synergistically with erythropoietin, stem cell factor, and interleukin-11 to enhance megakaryocyte colony growth and increases megakaryocyte ploidy in vitro. Blood (1995) 85: 1719-26.
-
(1995)
Blood
, vol.85
, pp. 1719-1726
-
-
Broudy, V.C.1
Lin, N.L.2
Kaushansky, K.3
-
37
-
-
0029035989
-
Purification and biologic characterization of plasma-derived megakaryocyte growth and development factor
-
Hunt P, Li Y-S, Nichol JL et al, Purification and biologic characterization of plasma-derived megakaryocyte growth and development factor. Blood (1995) 86: 540-7.
-
(1995)
Blood
, vol.86
, pp. 540-547
-
-
Hunt, P.1
Li, Y.-S.2
Nichol, J.L.3
-
38
-
-
0029121283
-
Modulation of megakaryocytopoiesis by thrombopoietin: The c-Mpl ligand
-
Banu N, Wang JF, Deng B et al, Modulation of megakaryocytopoiesis by thrombopoietin: the c-Mpl ligand. Blood (1995) 86: 1331-8.
-
(1995)
Blood
, vol.86
, pp. 1331-1338
-
-
Banu, N.1
Wang, J.F.2
Deng, B.3
-
39
-
-
0028332474
-
Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin
-
Kaushansky K, Lok S, Holly RD et al, Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature (1994) 369: 568-71.
-
(1994)
Nature
, vol.369
, pp. 568-571
-
-
Kaushansky, K.1
Lok, S.2
Holly, R.D.3
-
40
-
-
0029037953
-
The Mpl ligand or thrombopoietin or megakaryocyte growth and differentiation factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors
-
Debili N, Wendling F, Katz A et al, The Mpl ligand or thrombopoietin or megakaryocyte growth and differentiation factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors. Blood (1995) 86; 2516-25.
-
(1995)
Blood
, vol.86
, pp. 2516-2525
-
-
Debili, N.1
Wendling, F.2
Katz, A.3
-
41
-
-
0029963565
-
Functional regions of the mouse thrombopoietin receptor cytoplasmic domain: Evidence for a critical region which is involved in differentiation and can be complemented by erythropoietin
-
Porteu F, Rouyez M-C, Cocault L et al, Functional regions of the mouse thrombopoietin receptor cytoplasmic domain: evidence for a critical region which is involved in differentiation and can be complemented by erythropoietin. Mol Cell Biol (1996) 16: 2473-82.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2473-2482
-
-
Porteu, F.1
Rouyez, M.-C.2
Cocault, L.3
-
42
-
-
0028114123
-
In vitro megakaryocytopoietic and thrombopoietic activity of c-mpl ligand (TPO) on purified murine hematopoietic stem cells
-
Zeigler FC, deSauvage F, Widmer HR et al, In vitro megakaryocytopoietic and thrombopoietic activity of c-mpl ligand (TPO) on purified murine hematopoietic stem cells. Blood (1994) 84: 4045-52.
-
(1994)
Blood
, vol.84
, pp. 4045-4052
-
-
Zeigler, F.C.1
Desauvage, F.2
Widmer, H.R.3
-
43
-
-
0029022246
-
Recombinant human megakaryocyte growth and development factor (MGDF), a ligand for c-Mpl, produces functional human platelets in vitro
-
Choi ES, Hokom M, Bartley T et al, Recombinant human megakaryocyte growth and development factor (MGDF), a ligand for c-Mpl, produces functional human platelets in vitro. Stem Cells (1995) 13: 317-22.
-
(1995)
Stem Cells
, vol.13
, pp. 317-322
-
-
Choi, E.S.1
Hokom, M.2
Bartley, T.3
-
44
-
-
0028117771
-
The purification of megapoietin: A physiological regulator of megakaryocyte growth and platelet production
-
Kuter DJ, Beeler DL, Rosenberg RD, The purification of megapoietin: a physiological regulator of megakaryocyte growth and platelet production. Proc Natl Acad Sci USA (1994) 91: 11 108-12.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11108-11112
-
-
Kuter, D.J.1
Beeler, D.L.2
Rosenberg, R.D.3
-
45
-
-
0029804163
-
The role of megakaryocyte growth and development factor in terminal stages of thrombopoiesis
-
Choi ES, Hokom MM, Chen J-L et al, The role of megakaryocyte growth and development factor in terminal stages of thrombopoiesis. Br J Haematol (1996) 95: 227-33.
-
(1996)
Br J Haematol
, vol.95
, pp. 227-233
-
-
Choi, E.S.1
Hokom, M.M.2
Chen, J.-L.3
-
46
-
-
9344225757
-
Thrombopoietin primes human platelet aggregation induced by shear stress and by multiple agonists
-
Oda A, Miyakawa Y, Druker BJ et al, Thrombopoietin primes human platelet aggregation induced by shear stress and by multiple agonists. Blood (1996) 87: 4664-70.
-
(1996)
Blood
, vol.87
, pp. 4664-4670
-
-
Oda, A.1
Miyakawa, Y.2
Druker, B.J.3
-
47
-
-
0029912139
-
Effects of recombinant human megakaryocyte growth and development factor on platelet activation
-
Montruccio G, Brizzi MF, Calosso G et al, Effects of recombinant human megakaryocyte growth and development factor on platelet activation. Blood (1996) 87: 2762-8.
-
(1996)
Blood
, vol.87
, pp. 2762-2768
-
-
Montruccio, G.1
Brizzi, M.F.2
Calosso, G.3
-
48
-
-
0029080417
-
Megakaryocyte growth and development factor (MGDF) moderately enhances in-vitro platelet aggregation
-
Toombs CF, Young CH, Glaspy JA, Varnum BC, Megakaryocyte growth and development factor (MGDF) moderately enhances in-vitro platelet aggregation. Thromb Res (1995) 80: 23-33.
-
(1995)
Thromb Res
, vol.80
, pp. 23-33
-
-
Toombs, C.F.1
Young, C.H.2
Glaspy, J.A.3
Varnum, B.C.4
-
49
-
-
0027275160
-
Characterization of the murine Mpl proto-oncogene, a member of the hematopoietic cytokine receptor superfamily: Molecular cloning, chromosomal location and evidence for a function in cell growth
-
Vigon I, Florindo C, Fichelson S et al, Characterization of the murine Mpl proto-oncogene, a member of the hematopoietic cytokine receptor superfamily: molecular cloning, chromosomal location and evidence for a function in cell growth. Oncogene (1993) 8: 2607-15.
-
(1993)
Oncogene
, vol.8
, pp. 2607-2615
-
-
Vigon, I.1
Florindo, C.2
Fichelson, S.3
-
50
-
-
0028832719
-
Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity
-
Alexander WS, Metcalf D, Dunn AR, Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity. EMBO J (1995) 14: 5569-78.
-
(1995)
EMBO J
, vol.14
, pp. 5569-5578
-
-
Alexander, W.S.1
Metcalf, D.2
Dunn, A.R.3
-
51
-
-
0028933799
-
Signaling through the hematopoietic cytokine receptors
-
Ihle JN, Witthuhn BA, Quelle FW et al, Signaling through the hematopoietic cytokine receptors. Annu Rev Immunol (1995) 13: 369-98.
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 369-398
-
-
Ihle, J.N.1
Witthuhn, B.A.2
Quelle, F.W.3
-
52
-
-
0028910991
-
The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc and c-Mpl
-
Drachman JG, Griffin JD, Kaushansky K, The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc and c-Mpl. J Biol Chem (1995) 270: 4979-82.
-
(1995)
J Biol Chem
, vol.270
, pp. 4979-4982
-
-
Drachman, J.G.1
Griffin, J.D.2
Kaushansky, K.3
-
53
-
-
0029102815
-
TPO and IL-3 induce overlapping but distinct protein tyrosine phosphorylation in a myeloid precursor cell line
-
Dorsch M, Fan PD, Bogenberger J, Goff SP, TPO and IL-3 induce overlapping but distinct protein tyrosine phosphorylation in a myeloid precursor cell line. Biochem Biophys Res Commun (1995) 214: 424-31.
-
(1995)
Biochem Biophys Res Commun
, vol.214
, pp. 424-431
-
-
Dorsch, M.1
Fan, P.D.2
Bogenberger, J.3
Goff, S.P.4
-
54
-
-
0028864865
-
Megakaryocyte growth and development factor and interleukin-3 induce patterns of protein-tyrosine phosphorylation that correlate with dominant differentiation over proliferation of mpl-transfected 32D cells
-
Mu SX, Xia M, Elliot G et al, Megakaryocyte growth and development factor and interleukin-3 induce patterns of protein-tyrosine phosphorylation that correlate with dominant differentiation over proliferation of mpl-transfected 32D cells. Blood (1995) 86: 4532-43.
-
(1995)
Blood
, vol.86
, pp. 4532-4543
-
-
Mu, S.X.1
Xia, M.2
Elliot, G.3
-
55
-
-
0029010473
-
Thrombopoietin activates a STAT5-like factor in hematopoietic cells
-
Pallard C, Goullineux F, Benit L et al, Thrombopoietin activates a STAT5-like factor in hematopoietic cells. EMBO J (1995) 14: 2847-56.
-
(1995)
EMBO J
, vol.14
, pp. 2847-2856
-
-
Pallard, C.1
Goullineux, F.2
Benit, L.3
-
56
-
-
0028803575
-
TPO/c-Mpl ligand induces tyrosine phosphorylation of multiple cellular proteins including proto-oncogene products Vav and c-Cbl, and Ras signaling molecules
-
Sasaki K, Odai H, Hanazono Y et al, TPO/c-Mpl ligand induces tyrosine phosphorylation of multiple cellular proteins including proto-oncogene products Vav and c-Cbl, and Ras signaling molecules. Biochem Biophys Res Commun (1995) 216: 338-47.
-
(1995)
Biochem Biophys Res Commun
, vol.216
, pp. 338-347
-
-
Sasaki, K.1
Odai, H.2
Hanazono, Y.3
-
57
-
-
0028827190
-
Thrombopoietin, c-Mpl ligand, induces tyrosine phosphorylation of Tyk2, Jak2, and STAT3, and enhances agonists-induced aggregation in platelets in vitro
-
Ezumi Y, Takayama H, Okuma M, Thrombopoietin, c-Mpl ligand, induces tyrosine phosphorylation of Tyk2, Jak2, and STAT3, and enhances agonists-induced aggregation in platelets in vitro. FEBS Lett (1995) 374: 48-52.
-
(1995)
FEBS Lett
, vol.374
, pp. 48-52
-
-
Ezumi, Y.1
Takayama, H.2
Okuma, M.3
-
58
-
-
0029052479
-
Recombinant thrombopoietin induces rapid protein tyrosine phosphorylation of Janus kinase 2 and Shc in human blood platelets
-
Miyakawa Y, Oda A, Druker BJ et al, Recombinant thrombopoietin induces rapid protein tyrosine phosphorylation of Janus kinase 2 and Shc in human blood platelets. Blood (1995) 86: 23-7.
-
(1995)
Blood
, vol.86
, pp. 23-27
-
-
Miyakawa, Y.1
Oda, A.2
Druker, B.J.3
-
59
-
-
0029800869
-
Tyrosine-599 of the c-Mpl receptor is required for Shc phosphorylation and the induction of cellular differentiation
-
Alexander WS, Maurer AB, Novak U, Harrison-Smith M, Tyrosine-599 of the c-Mpl receptor is required for Shc phosphorylation and the induction of cellular differentiation. EMBO J (1996) 15: 6531-40.
-
(1996)
EMBO J
, vol.15
, pp. 6531-6540
-
-
Alexander, W.S.1
Maurer, A.B.2
Novak, U.3
Harrison-Smith, M.4
-
60
-
-
0030900247
-
Dissecting the thrombopoietin receptor: Functional elements of the Mpl cytoplasmic domain
-
Drachman JG, Kaushansky K, Dissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domain. Proc Natl Acad Sci USA (1997) 94: 2350-5.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2350-2355
-
-
Drachman, J.G.1
Kaushansky, K.2
-
61
-
-
0030052617
-
Thrombopoietin induces tyrosine phosphorylation of STAT3 and STAT5 in human blood platelets
-
Miyakawa Y, Oda A, Druker BJ et al, Thrombopoietin induces tyrosine phosphorylation of STAT3 and STAT5 in human blood platelets. Blood (1996) 87: 439-46.
-
(1996)
Blood
, vol.87
, pp. 439-446
-
-
Miyakawa, Y.1
Oda, A.2
Druker, B.J.3
-
62
-
-
0029117375
-
The thrombopoietin receptor c-Mpl activates Jak2 and Tyk2 tyrosine kinases
-
Sattler M, Durstin MA, Frank DA et al, The thrombopoietin receptor c-Mpl activates Jak2 and Tyk2 tyrosine kinases. Exp Hematol (1995) 23: 1040-8.
-
(1995)
Exp Hematol
, vol.23
, pp. 1040-1048
-
-
Sattler, M.1
Durstin, M.A.2
Frank, D.A.3
-
63
-
-
0029051429
-
Thrombopoietin induces tyrosine phosphorylation and activation of the Janus kinase JAK2
-
Tortolani PJ, Johnston JA, Bacon CM et al, Thrombopoietin induces tyrosine phosphorylation and activation of the Janus kinase JAK2. Blood (1995) 85: 3444-51.
-
(1995)
Blood
, vol.85
, pp. 3444-3451
-
-
Tortolani, P.J.1
Johnston, J.A.2
Bacon, C.M.3
-
64
-
-
0029049709
-
Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation
-
Gurney AL, Wong SC, Henzel WJ, deSauvage FJ, Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation. Proc Natl Acad Sci USA (1995) 92: 5292-6.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5292-5296
-
-
Gurney, A.L.1
Wong, S.C.2
Henzel, W.J.3
DeSauvage, F.J.4
-
65
-
-
0029150706
-
Thrombopoietin (TPO) induces tyrosine phosphorylation and activation of STAT3 and STAT5
-
Bacon CM, Tortolani PJ, Shimosaka A et al, Thrombopoietin (TPO) induces tyrosine phosphorylation and activation of STAT3 and STAT5. FEBS Lett (1995) 370: 63-8.
-
(1995)
FEBS Lett
, vol.370
, pp. 63-68
-
-
Bacon, C.M.1
Tortolani, P.J.2
Shimosaka, A.3
-
66
-
-
0030942104
-
Tec protein tyrosine kinase is involved in the thrombopoietin/c-Mpl signaling pathway
-
Yamashita Y, Miyazato A, Shimizu R et al, Tec protein tyrosine kinase is involved in the thrombopoietin/c-Mpl signaling pathway. Exp Hematol (1997) 25: 211-16.
-
(1997)
Exp Hematol
, vol.25
, pp. 211-216
-
-
Yamashita, Y.1
Miyazato, A.2
Shimizu, R.3
-
68
-
-
0029960265
-
Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietin receptor c-Mpl
-
Alexander WS, Roberts AW, Nicola NA et al, Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietin receptor c-Mpl. Blood (1996) 87: 2162-70.
-
(1996)
Blood
, vol.87
, pp. 2162-2170
-
-
Alexander, W.S.1
Roberts, A.W.2
Nicola, N.A.3
-
69
-
-
0030024685
-
Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin
-
deSauvage FJ, Carver-Moore K, Luoh S-M et al, Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin. J Exp Med (1996) 183: 651-6.
-
(1996)
J Exp Med
, vol.183
, pp. 651-656
-
-
Sauvage, F.J.1
Carver-Moore, K.2
Luoh, S.-M.3
-
70
-
-
0029684417
-
Low levels of erythroid and myeloid progenitors in thrombopoietin and c-mpl-deficient mice
-
Carver-Moore K, Broxmeyer HE, Luoh S-M et al, Low levels of erythroid and myeloid progenitors in thrombopoietin and c-mpl-deficient mice. Blood (1996) 88: 803-8.
-
(1996)
Blood
, vol.88
, pp. 803-808
-
-
Carver-Moore, K.1
Broxmeyer, H.E.2
Luoh, S.-M.3
-
71
-
-
0029027918
-
Recombinant human thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors
-
Kobayashi M, Laver JH, Kato T et al, Recombinant human thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors. Blood (1995) 86: 2494-9.
-
(1995)
Blood
, vol.86
, pp. 2494-2499
-
-
Kobayashi, M.1
Laver, J.H.2
Kato, T.3
-
73
-
-
0031017147
-
- progenitor cells cultured in serum-depleted medium
-
- progenitor cells cultured in serum-depleted medium. Stem Cells (1997) 15: 18-32.
-
(1997)
Stem Cells
, vol.15
, pp. 18-32
-
-
Birkmann, J.1
Oez, S.2
Smetak, M.3
-
74
-
-
0031033837
-
Mpl ligand (MGDF) alone and in combination with stem cell factor (SCF) promotes proliferation and survival of human megakaryocyte, erythroid and granulocyte/macrophage progenitors
-
Rasko JIJ, O'Flaherty E, Begley CG, Mpl ligand (MGDF) alone and in combination with stem cell factor (SCF) promotes proliferation and survival of human megakaryocyte, erythroid and granulocyte/macrophage progenitors. Stem Cells (1997) 15: 33-42.
-
(1997)
Stem Cells
, vol.15
, pp. 33-42
-
-
Jij, R.1
O'Flaherty, E.2
Begley, C.G.3
-
75
-
-
0030039567
-
Thrombopoietin, the ligand for the Mpl receptor, synergizes with Steel factor and other early acting cytokines in supporting proliferation of primitive hematopoietic progenitors of mice
-
Ku H, Yonemura Y, Kaushansky K, Ogawa M, Thrombopoietin, the ligand for the Mpl receptor, synergizes with Steel factor and other early acting cytokines in supporting proliferation of primitive hematopoietic progenitors of mice. Blood (1996) 87: 4544-51.
-
(1996)
Blood
, vol.87
, pp. 4544-4551
-
-
Ku, H.1
Yonemura, Y.2
Kaushansky, K.3
Ogawa, M.4
-
76
-
-
0030014681
-
The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells
-
Sitnicka E, Lin N, Priestly GV et al, The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells. Blood (1996) 87: 4998-5005.
-
(1996)
Blood
, vol.87
, pp. 4998-5005
-
-
Sitnicka, E.1
Lin, N.2
Priestly, G.V.3
-
77
-
-
0029912731
-
Thrombopoietin, but not erythropoietin, directly stimulates multilineage growth of primitive murine bone marrow progenitor cells in synergy with early acting cytokines: Distinct interactions with the ligand for c-kit and FLT3
-
Ramsfjell V, Borge OJ, Veiby OP et al, Thrombopoietin, but not erythropoietin, directly stimulates multilineage growth of primitive murine bone marrow progenitor cells in synergy with early acting cytokines: distinct interactions with the ligand for c-kit and FLT3. Blood (1996) 88: 4481-92.
-
(1996)
Blood
, vol.88
, pp. 4481-4492
-
-
Ramsfjell, V.1
Borge, O.J.2
Veiby, O.P.3
-
78
-
-
0344655326
-
Hematopoiesis in mice lacking the entire granulocyte-macrophage colony-stimulating facror/interleukin-2/interleukin-5 functions
-
Nishinakamura R, Miyajima A, Mee PJ et al, Hematopoiesis in mice lacking the entire granulocyte-macrophage colony-stimulating facror/interleukin-2/interleukin-5 functions. Blood (1996) 88: 2458-64.
-
(1996)
Blood
, vol.88
, pp. 2458-2464
-
-
Nishinakamura, R.1
Miyajima, A.2
Mee, P.J.3
-
79
-
-
0030847329
-
Adult mice with targeted mutation of the interleukin-11 receptor (IL-11Ra) display normal hematopoiesis
-
Nandurkar HH, Robb L, Tarlinton D et al, Adult mice with targeted mutation of the interleukin-11 receptor (IL-11Ra) display normal hematopoiesis. Blood (1997) 90: 2148-59.
-
(1997)
Blood
, vol.90
, pp. 2148-2159
-
-
Nandurkar, H.H.1
Robb, L.2
Tarlinton, D.3
-
80
-
-
0028266906
-
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion
-
Poli V, Balena R, Fattori E et al, Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion EMBO J (1994) 13: 1189-96.
-
(1994)
EMBO J
, vol.13
, pp. 1189-1196
-
-
Poli, V.1
Balena, R.2
Fattori, E.3
-
81
-
-
0029923645
-
Relative reactivity of platelets from thrombopoietin- and interleukin-6-treated dogs
-
Peng J, Friese P, Wolf RF et al, Relative reactivity of platelets from thrombopoietin- and interleukin-6-treated dogs. Blood (1996) 87: 4158-63.
-
(1996)
Blood
, vol.87
, pp. 4158-4163
-
-
Peng, J.1
Friese, P.2
Wolf, R.F.3
-
82
-
-
0029062371
-
Recombinant human megakaryocyte growth and development factor stimulates thrombocytopoiesis in normal nonhuman primates
-
Farese AM, Hunt P, Boone T, MacVittie TJ, Recombinant human megakaryocyte growth and development factor stimulates thrombocytopoiesis in normal nonhuman primates. Blood (1995) 86: 54-9.
-
(1995)
Blood
, vol.86
, pp. 54-59
-
-
Farese, A.M.1
Hunt, P.2
Boone, T.3
MacVittie, T.J.4
-
83
-
-
0029943307
-
Dose-response effects of pegylated human megakaryocyte growth and development factor on platelet production and function in nonhuman primates
-
Harker LA, Marzec UM, Hunt P et al, Dose-response effects of pegylated human megakaryocyte growth and development factor on platelet production and function in nonhuman primates. Blood (1996) 88: 511-21.
-
(1996)
Blood
, vol.88
, pp. 511-521
-
-
Harker, L.A.1
Marzec, U.M.2
Hunt, P.3
-
84
-
-
0030942587
-
A single injection of pegylated megakaryocyte growth and development factor (MODF) into mice is sufficient to produce a profound stimulation of megakaryocyte frequency, size and ploidization
-
Arnold JT, Daw NC, Stenberg PE et al, A single injection of pegylated megakaryocyte growth and development factor (MODF) into mice is sufficient to produce a profound stimulation of megakaryocyte frequency, size and ploidization. Blood (1997) 89: 823-33.
-
(1997)
Blood
, vol.89
, pp. 823-833
-
-
Arnold, J.T.1
Daw, N.C.2
Stenberg, P.E.3
-
85
-
-
0029864161
-
Thrombopoietin expands erythroid, granulocyte-macrophage and megakaryocytic progenitor cells in normal and myelosuppressed mice
-
Kaushansky K, Lin N, Grossmann A et al, Thrombopoietin expands erythroid, granulocyte-macrophage and megakaryocytic progenitor cells in normal and myelosuppressed mice. Exp Hematol (1996) 23: 265-9.
-
(1996)
Exp Hematol
, vol.23
, pp. 265-269
-
-
Kaushansky, K.1
Lin, N.2
Grossmann, A.3
-
86
-
-
0029963122
-
Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multi-lineage hematopoietic reconstitution in nonhuman primates after radiation induced marrow aplasia
-
Farese AM, Hunt P, Grab LB, MacVittie TJ, Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multi-lineage hematopoietic reconstitution in nonhuman primates after radiation induced marrow aplasia. J Clin Invest (1996) 97: 2145-51.
-
(1996)
J Clin Invest
, vol.97
, pp. 2145-2151
-
-
Farese, A.M.1
Hunt, P.2
Grab, L.B.3
MacVittie, T.J.4
-
87
-
-
0029796257
-
Thrombopoietin accelerates platelet, red blood cell, and neutrophil recovery in myelosuppressed mice
-
Grossmann A, Lenox J, Ren HP et al, Thrombopoietin accelerates platelet, red blood cell, and neutrophil recovery in myelosuppressed mice. Exp Hematol (1996) 24: 1238-46.
-
(1996)
Exp Hematol
, vol.24
, pp. 1238-1246
-
-
Grossmann, A.1
Lenox, J.2
Ren, H.P.3
-
88
-
-
0029897491
-
Systemic hematologic effects of PEG-rHuMGDF-induced megakaryocyte hyperplasia in mice
-
Ulich TR, del Castillo J, Senaldi G et al, Systemic hematologic effects of PEG-rHuMGDF-induced megakaryocyte hyperplasia in mice. Blood (1996) 87: 5006-15.
-
(1996)
Blood
, vol.87
, pp. 5006-5015
-
-
Ulich, T.R.1
Del Castillo, J.2
Senaldi, G.3
-
89
-
-
0029992540
-
Synergistic effects of thrombopoietin and granulocyte colony-stimulating factor on neutrophil recovery in myelosuppressed mice
-
Grossmann A, Lenox J, Deisher TA et al, Synergistic effects of thrombopoietin and granulocyte colony-stimulating factor on neutrophil recovery in myelosuppressed mice. Blood (1996) 88: 3363-70.
-
(1996)
Blood
, vol.88
, pp. 3363-3370
-
-
Grossmann, A.1
Lenox, J.2
Deisher, T.A.3
-
90
-
-
0028787175
-
Accelerated reconstitution of platelets and erythrocytes following syngeneic transplantation of bone marrow cells derived from thrombopoietin pretreated donor mice
-
Fibbe WE, Heemskerk DPM, Laterveer L et al, Accelerated reconstitution of platelets and erythrocytes following syngeneic transplantation of bone marrow cells derived from thrombopoietin pretreated donor mice. Blood (1995) 86: 3308-13.
-
(1995)
Blood
, vol.86
, pp. 3308-3313
-
-
Fibbe, W.E.1
Heemskerk, D.P.M.2
Laterveer, L.3
-
91
-
-
0029839244
-
Megakaryocyte growth and development factor stimulates enhanced platelet recovery in mice after bone marrow transplantation
-
Molineux G, Hartley CA, McElroy P et al, Megakaryocyte growth and development factor stimulates enhanced platelet recovery in mice after bone marrow transplantation. Blood (1996) 88: 1509-14.
-
(1996)
Blood
, vol.88
, pp. 1509-1514
-
-
Molineux, G.1
Hartley, C.A.2
McElroy, P.3
-
92
-
-
0028843848
-
Chronic exposure to retroviral vector encoded MGDF (mpl-ligand) induces lineage-specific growth and differentiation of megakaryocytes in mice
-
Yan XQ, Lacey D, Fletcher F et al, Chronic exposure to retroviral vector encoded MGDF (mpl-ligand) induces lineage-specific growth and differentiation of megakaryocytes in mice. Blood (1995) 86: 4025-33.
-
(1995)
Blood
, vol.86
, pp. 4025-4033
-
-
Yan, X.Q.1
Lacey, D.2
Fletcher, F.3
-
93
-
-
0029956149
-
A model of myelofibrosis and osteosclerosis in mice induced by overexpressing thrombopoietin (mpl ligand): Reversal of disease by bone marrow transplantation
-
Yan XQ, Lacey D, Hill D et al, A model of myelofibrosis and osteosclerosis in mice induced by overexpressing thrombopoietin (mpl ligand): reversal of disease by bone marrow transplantation. Blood (1996) 88: 402-9.
-
(1996)
Blood
, vol.88
, pp. 402-409
-
-
Yan, X.Q.1
Lacey, D.2
Hill, D.3
-
94
-
-
0029150347
-
Thrombopoietin expands erythroid progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive therapy
-
Kaushansky K, Broudy VC, Grossmann A et al, Thrombopoietin expands erythroid progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive therapy. J Clin Invest (1995) 96: 1683-7.
-
(1995)
J Clin Invest
, vol.96
, pp. 1683-1687
-
-
Kaushansky, K.1
Broudy, V.C.2
Grossmann, A.3
-
95
-
-
10344235968
-
Thrombopoietic effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in patients with advanced cancer
-
Basser RJL, Rasko JEJ, Clarke K et al, Thrombopoietic effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in patients with advanced cancer. Lancet (1996) 348: 1279-81.
-
(1996)
Lancet
, vol.348
, pp. 1279-1281
-
-
Basser, R.J.L.1
Rasko, J.E.J.2
Clarke, K.3
-
96
-
-
10344238601
-
Administration of pegylated recombinant human megakaryocyte growth and development factor to humans stimulates the production of functional platelets that show no evidence of in vivo activation
-
O'Malley CJ, Rasko JEJ, Basser RL et al, Administration of pegylated recombinant human megakaryocyte growth and development factor to humans stimulates the production of functional platelets that show no evidence of in vivo activation. Blood (1996) 88: 3288-98.
-
(1996)
Blood
, vol.88
, pp. 3288-3298
-
-
O'Malley, C.J.1
Rasko, J.E.J.2
Basser, R.L.3
-
97
-
-
17944389931
-
Randomised, blinded, placebo-controlled phase 1 trial of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) with filgrastim after dose-intensive chemotherapy in patients with advanced cancer
-
Basser RL, Rasko JEJ, Clarke K et al, Randomised, blinded, placebo-controlled phase 1 trial of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) with filgrastim after dose-intensive chemotherapy in patients with advanced cancer. Blood (1997) 89: 3118-28.
-
(1997)
Blood
, vol.89
, pp. 3118-3128
-
-
Basser, R.L.1
Rasko, J.E.J.2
Clarke, K.3
-
98
-
-
8544258752
-
Multilineage mobilisation of peripheral blood progenitor cells in humans following administration of PEG-rHuMGDF
-
Rasko JEJ, Basser RL, Boyd J et al, Multilineage mobilisation of peripheral blood progenitor cells in humans following administration of PEG-rHuMGDF. Br J Haematol (1997) 97: 871-80.
-
(1997)
Br J Haematol
, vol.97
, pp. 871-880
-
-
Rasko, J.E.J.1
Basser, R.L.2
Boyd, J.3
-
99
-
-
0031049879
-
Effects of polyethylene glycol-conjugated recombinant human megakaryocyte growth and development factor on platelet counts for chemotherapy for lung cancer
-
Franucchi M, Glasby J, Crawford J et al, Effects of polyethylene glycol-conjugated recombinant human megakaryocyte growth and development factor on platelet counts for chemotherapy for lung cancer. N Engl J Med (1997) 336: 404-9.
-
(1997)
N Engl J Med
, vol.336
, pp. 404-409
-
-
Franucchi, M.1
Glasby, J.2
Crawford, J.3
-
100
-
-
0030966361
-
Stimulation of megakaryocyte and platelet production of a single dose of recombinant human thrombopoietin in patients with cancer
-
Vadhan-Raj S, Murray LJ, Bueso-Ramos C et al, Stimulation of megakaryocyte and platelet production of a single dose of recombinant human thrombopoietin in patients with cancer. Ann Int Med (1997) 126: 673-81.
-
(1997)
Ann Int Med
, vol.126
, pp. 673-681
-
-
Vadhan-Raj, S.1
Murray, L.J.2
Bueso-Ramos, C.3
-
101
-
-
0028133268
-
Reticulated platelet counts in patients undergoing autologous bone marrow transplantation: An aid in assessing marrow recovery
-
Romp KG, Peters WP, Hoffman M, Reticulated platelet counts in patients undergoing autologous bone marrow transplantation: an aid in assessing marrow recovery. Am J Hematol (1994) 46: 319-24.
-
(1994)
Am J Hematol
, vol.46
, pp. 319-324
-
-
Romp, K.G.1
Peters, W.P.2
Hoffman, M.3
-
102
-
-
0028927699
-
Demonstration that thiazole-orange-positive platelets in the dog are less than 24 hours old
-
Dale GL, Friese P, Hynes LA, Burstyn SA, Demonstration that thiazole-orange-positive platelets in the dog are less than 24 hours old. Blood (1995) 85: 1822-5.
-
(1995)
Blood
, vol.85
, pp. 1822-1825
-
-
Dale, G.L.1
Friese, P.2
Hynes, L.A.3
Burstyn, S.A.4
-
103
-
-
0026067028
-
An improved method for measuring plasma glycocalicin in the investigation of causes of thrombocytopenia
-
Wilcox GR, Berndt MC, Mehrabani PA et al, An improved method for measuring plasma glycocalicin in the investigation of causes of thrombocytopenia. Platelets (1991) 2: 45-50.
-
(1991)
Platelets
, vol.2
, pp. 45-50
-
-
Wilcox, G.R.1
Berndt, M.C.2
Mehrabani, P.A.3
-
104
-
-
0028047501
-
Glycocalicin: A new assay - The normal plasma levels and its potential usefulness in selected diseases
-
Beer JH, Buchi L, Steiner B, Glycocalicin: a new assay - the normal plasma levels and its potential usefulness in selected diseases. Blood (1994) 83: 691-702.
-
(1994)
Blood
, vol.83
, pp. 691-702
-
-
Beer, J.H.1
Buchi, L.2
Steiner, B.3
-
105
-
-
0022642793
-
Biological properties in vitro of a recombinant human granulocyte-macrophage colony-stimulating factor
-
Metcalf D, Begley CG, Johnson GR et al, Biological properties in vitro of a recombinant human granulocyte-macrophage colony-stimulating factor. Blood (1986) 67: 37-45.
-
(1986)
Blood
, vol.67
, pp. 37-45
-
-
Metcalf, D.1
Begley, C.G.2
Johnson, G.R.3
-
106
-
-
0022539985
-
Survival in vitro of mature neutrophils and eosinophils in a lineage-specific manner, a rapid sensitive microassay for colony-stimulating factors
-
Begley CG, Lopez AF, Nicola NA et al, Survival in vitro of mature neutrophils and eosinophils in a lineage-specific manner, a rapid sensitive microassay for colony-stimulating factors. Blood (1986) 68: 162-6.
-
(1986)
Blood
, vol.68
, pp. 162-166
-
-
Begley, C.G.1
Lopez, A.F.2
Nicola, N.A.3
-
107
-
-
0028820319
-
Regulation of platelet activation in vitro by the c-Mpl ligand, thrombopoietin
-
Chen J, Herceg-Harjacek L, Groopman JE, Grabarek J, Regulation of platelet activation in vitro by the c-Mpl ligand, thrombopoietin. Blood (1995) 86: 4054-62.
-
(1995)
Blood
, vol.86
, pp. 4054-4062
-
-
Chen, J.1
Herceg-Harjacek, L.2
Groopman, J.E.3
Grabarek, J.4
-
108
-
-
0029979883
-
Thrombopoietin potentiates activation of human platelets in association with JAK2 and TYK2 phosphorylation
-
Rodriguez-Linarea B, Watson SP, Thrombopoietin potentiates activation of human platelets in association with JAK2 and TYK2 phosphorylation. Biochem J (1996) 316: 93-8.
-
(1996)
Biochem J
, vol.316
, pp. 93-98
-
-
Rodriguez-Linarea, B.1
Watson, S.P.2
-
109
-
-
0024271198
-
Effects of recombinant human granulocyte-colony stimulating factor on hematopoietic progenitor cells in cancer patients
-
Dührsen U, Villeval J-L, Boyd J et al, Effects of recombinant human granulocyte-colony stimulating factor on hematopoietic progenitor cells in cancer patients. Blood (1988) 72: 2074-81.
-
(1988)
Blood
, vol.72
, pp. 2074-2081
-
-
Dührsen, U.1
Villeval, J.-L.2
Boyd, J.3
-
110
-
-
0026504705
-
Effect of peripheral-blood progenitor cells mobilised by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy
-
Sheridan WP, Begley CG, Juttner CA et al, Effect of peripheral-blood progenitor cells mobilised by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy. Lancet (1992) 339: 640-1.
-
(1992)
Lancet
, vol.339
, pp. 640-641
-
-
Sheridan, W.P.1
Begley, C.G.2
Juttner, C.A.3
-
111
-
-
0026439358
-
Prior chemotherapy does not prevent effective mobilisation by G-CSF of peripheral blood progenitor cells
-
DeLuca E, Sheridan WP, Watson D et al, Prior chemotherapy does not prevent effective mobilisation by G-CSF of peripheral blood progenitor cells. Br J Cancer (1992) 66: 893-9.
-
(1992)
Br J Cancer
, vol.66
, pp. 893-899
-
-
Deluca, E.1
Sheridan, W.P.2
Watson, D.3
-
112
-
-
0030783509
-
Enhanced levels and enhanced clonogenic capacity of blood progenitor cells following administration of SCF plus G-CSF to humans
-
Begley CG, Basser RL, Mansfield R et al, Enhanced levels and enhanced clonogenic capacity of blood progenitor cells following administration of SCF plus G-CSF to humans. Blood (1997) 90: 3378-89.
-
(1997)
Blood
, vol.90
, pp. 3378-3389
-
-
Begley, C.G.1
Basser, R.L.2
Mansfield, R.3
-
114
-
-
0029671277
-
Coexpression of thrombopoietin and c-mpl genes in acute myeloblastic leukemic cells
-
Matsumura I, Kanakura Y, Ikeda H et al, Coexpression of thrombopoietin and c-mpl genes in acute myeloblastic leukemic cells. Leukemia (1996) 10: 91-4.
-
(1996)
Leukemia
, vol.10
, pp. 91-94
-
-
Matsumura, I.1
Kanakura, Y.2
Ikeda, H.3
-
115
-
-
0029932842
-
Expression of the receptor MPL and proliferative effects of its ligand thrombopoietin on human leukemia cells
-
Quentmeier H, Zaborski M, Graf G et al, Expression of the receptor MPL and proliferative effects of its ligand thrombopoietin on human leukemia cells. Leukemia (1996) 10: 297-310.
-
(1996)
Leukemia
, vol.10
, pp. 297-310
-
-
Quentmeier, H.1
Zaborski, M.2
Graf, G.3
-
116
-
-
0029019022
-
Growth response of acute myeloblastic leukemia cells to recombinant human thrombopoietin
-
Matsumura I, Kanakura Y, Kato T et al, Growth response of acute myeloblastic leukemia cells to recombinant human thrombopoietin. Blood (1995) 86: 703-9.
-
(1995)
Blood
, vol.86
, pp. 703-709
-
-
Matsumura, I.1
Kanakura, Y.2
Kato, T.3
-
117
-
-
10244231042
-
The biologic properties of recombinant human thrombopoietin in the proliferation and megakaryocytic differentiation of acute myeloblastic leukemia cells
-
Matsumura I, Kanakura Y, Kato T et al, The biologic properties of recombinant human thrombopoietin in the proliferation and megakaryocytic differentiation of acute myeloblastic leukemia cells. Blood (1996) 88: 3074-82.
-
(1996)
Blood
, vol.88
, pp. 3074-3082
-
-
Matsumura, I.1
Kanakura, Y.2
Kato, T.3
-
118
-
-
0344073862
-
A randomised, double-blind, placebo-controlled study using PEG-rHuMGDF as an adjunct to chemotherapy for adults with de-novo acute myeloid leukemia (AML): Early results
-
abst
-
Archimbaud E, Ottmann O, Liu Yin JA et al, A randomised, double-blind, placebo-controlled study using PEG-rHuMGDF as an adjunct to chemotherapy for adults with de-novo acute myeloid leukemia (AML): early results. Blood 88(Suppl 1): 447a (abst).
-
Blood
, vol.88
, Issue.1 SUPPL.
-
-
Archimbaud, E.1
Ottmann, O.2
Liu Yin, J.A.3
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