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Volumn 336, Issue 6, 1997, Pages 404-409

Effects of polyethylene glycol-conjugated recombinant human megakaryocyte growth and development factor on platelet counts after chemotherapy for lung cancer

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; MACROGOL; MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; PACLITAXEL; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

EID: 0031049879     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199702063360603     Document Type: Article
Times cited : (276)

References (46)
  • 1
    • 0002955346 scopus 로고
    • Principles of platelet transfusion therapy
    • Hoffman R, Benz EJ Jr, Shattil SJ, Furie B, Cohen HJ, eds. New York: Churchill Livingstone
    • Slichter SJ. Principles of platelet transfusion therapy. In: Hoffman R, Benz EJ Jr, Shattil SJ, Furie B, Cohen HJ, eds. Hematology: basic principles and practice. New York: Churchill Livingstone, 1991:1610-22.
    • (1991) Hematology: Basic Principles and Practice , pp. 1610-1622
    • Slichter, S.J.1
  • 2
    • 1842323821 scopus 로고
    • Transfusion-transmitted diseases
    • Hoffman R, Benz EJ, Shattil SJ, Furie B, Cohen HJ, eds. New York: Churchill Livingstone
    • Menitove JE. Transfusion-transmitted diseases. In: Hoffman R, Benz EJ, Shattil SJ, Furie B, Cohen HJ, eds. Hematology: basic principles and practice. New York: Churchill Livingstone, 1991:1651-60.
    • (1991) Hematology: Basic Principles and Practice , pp. 1651-1660
    • Menitove, J.E.1
  • 3
    • 0028199208 scopus 로고
    • Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo
    • Lok S, Kaushansky K, Holly RD, et al. Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature 1994;369:565-8.
    • (1994) Nature , vol.369 , pp. 565-568
    • Lok, S.1    Kaushansky, K.2    Holly, R.D.3
  • 4
    • 0028302409 scopus 로고
    • Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mp1 ligand
    • de Sauvage FJ, Hass PE, Spencer SD, et al. Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mp1 ligand. Nature 1994;369: 533-8.
    • (1994) Nature , vol.369 , pp. 533-538
    • De Sauvage, F.J.1    Hass, P.E.2    Spencer, S.D.3
  • 5
    • 0028343099 scopus 로고
    • Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl
    • Bartley TD, Bogenberger J, Hunt P, et al. Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. Cell 1994;77:1117-24.
    • (1994) Cell , vol.77 , pp. 1117-1124
    • Bartley, T.D.1    Bogenberger, J.2    Hunt, P.3
  • 6
    • 0028176283 scopus 로고
    • cMpl ligand is a humoral regulator of megakaryocytopoiesis
    • Wendling F, Maraskovsky E, Debili N, et al. cMpl ligand is a humoral regulator of megakaryocytopoiesis. Nature 1994;369:571-4.
    • (1994) Nature , vol.369 , pp. 571-574
    • Wendling, F.1    Maraskovsky, E.2    Debili, N.3
  • 7
    • 0028332474 scopus 로고
    • Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin
    • Kaushansky K, Lok S, Holly RD, et al. Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature 1994;369:568-71.
    • (1994) Nature , vol.369 , pp. 568-571
    • Kaushansky, K.1    Lok, S.2    Holly, R.D.3
  • 8
    • 0028117771 scopus 로고
    • The purification of megapoietin: A physiological regulator of megakaryocyte growth and platelet production
    • Kuter DJ, Beeler DL, Rosenberg RD. The purification of megapoietin: a physiological regulator of megakaryocyte growth and platelet production. Proc Natl Acad Sci U S A 1994;91:11104-8.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 11104-11108
    • Kuter, D.J.1    Beeler, D.L.2    Rosenberg, R.D.3
  • 9
    • 0029148579 scopus 로고
    • Purification and characterization of thrombopoietin
    • Tokyo
    • Kato T, Ogami K, Shimada Y, et al. Purification and characterization of thrombopoietin. J Biochem (Tokyo) 1995;118:229-36.
    • (1995) J Biochem , vol.118 , pp. 229-236
    • Kato, T.1    Ogami, K.2    Shimada, Y.3
  • 10
    • 0029035989 scopus 로고
    • Purification and biologic characterization of plasma-derived megakaryocyte growth and development factor
    • Hunt P, Li YS, Nichol JL, et al. Purification and biologic characterization of plasma-derived megakaryocyte growth and development factor. Blood 1995;86:540-7.
    • (1995) Blood , vol.86 , pp. 540-547
    • Hunt, P.1    Li, Y.S.2    Nichol, J.L.3
  • 11
    • 0029046966 scopus 로고
    • Megakaryocyte growth and development factor: Analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy-induced thrombocytopenia
    • Nichol JL, Hokom MM, Hornkohl A, et al. Megakaryocyte growth and development factor: analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy-induced thrombocytopenia. J Clin Invest 1995;95:2973-8.
    • (1995) J Clin Invest , vol.95 , pp. 2973-2978
    • Nichol, J.L.1    Hokom, M.M.2    Hornkohl, A.3
  • 12
    • 0029030356 scopus 로고
    • The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit
    • Kuter DJ, Rosenberg RD. The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit. Blood 1995;85:2720-30.
    • (1995) Blood , vol.85 , pp. 2720-2730
    • Kuter, D.J.1    Rosenberg, R.D.2
  • 13
    • 0029022246 scopus 로고
    • Recombinant human megakaryocyte growth and development factor (rHuMGDF), a ligand for c-Mpl, produces functional human platelets in vitro
    • Dayt
    • Choi ES, Hokom M, Bartley T, et al. Recombinant human megakaryocyte growth and development factor (rHuMGDF), a ligand for c-Mpl, produces functional human platelets in vitro. Stem Cells (Dayt) 1995;13: 317-22.
    • (1995) Stem Cells , vol.13 , pp. 317-322
    • Choi, E.S.1    Hokom, M.2    Bartley, T.3
  • 15
    • 0029960265 scopus 로고    scopus 로고
    • Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietin receptor c-Mpl
    • Alexander WS, Roberts AW, Nicola NA, Li R, Metcalf D. Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietin receptor c-Mpl. Blood 1996;87:2162-70.
    • (1996) Blood , vol.87 , pp. 2162-2170
    • Alexander, W.S.1    Roberts, A.W.2    Nicola, N.A.3    Li, R.4    Metcalf, D.5
  • 16
    • 0030024685 scopus 로고    scopus 로고
    • Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin
    • de Sauvage FJ, Carver-Moore K, Luoh S-M, et al. Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin. J Exp Med 1996;183:651-6.
    • (1996) J Exp Med , vol.183 , pp. 651-656
    • De Sauvage, F.J.1    Carver-Moore, K.2    Luoh, S.-M.3
  • 17
    • 0029897491 scopus 로고    scopus 로고
    • Systemic hematologic effects of PEG-rHuMGDF-induced megakaryocyte hyperplasia in mice
    • Ulich TR, del Castillo J, Senaldi G, et al. Systemic hematologic effects of PEG-rHuMGDF-induced megakaryocyte hyperplasia in mice. Blood 1996;87:5006-15.
    • (1996) Blood , vol.87 , pp. 5006-5015
    • Ulich, T.R.1    Del Castillo, J.2    Senaldi, G.3
  • 18
    • 0028803099 scopus 로고
    • Pegylated megakaryocyte growth and development factor abrogates the lethal thrombocytopenia associated with carboplatin and irradiation in mice
    • Hokom MM, Lacey D, Kinstler OB, et al. Pegylated megakaryocyte growth and development factor abrogates the lethal thrombocytopenia associated with carboplatin and irradiation in mice. Blood 1995;86: 4486-92.
    • (1995) Blood , vol.86 , pp. 4486-4492
    • Hokom, M.M.1    Lacey, D.2    Kinstler, O.B.3
  • 19
    • 0029062371 scopus 로고
    • Recombinant human megakaryocyte growth and development factor stimulates thrombocytopoiesis in normal nonhuman primates
    • Farese AM, Hunt P, Boone T, MacVittie TJ. Recombinant human megakaryocyte growth and development factor stimulates thrombocytopoiesis in normal nonhuman primates. Blood 1995;86:54-9.
    • (1995) Blood , vol.86 , pp. 54-59
    • Farese, A.M.1    Hunt, P.2    Boone, T.3    MacVittie, T.J.4
  • 20
    • 0029943307 scopus 로고    scopus 로고
    • Dose-response effects of pegylated megakaryocyte growth and development factor on platelet production and function in nonhuman primates
    • Harker LA, Marzec UM, Hunt P, et al. Dose-response effects of pegylated megakaryocyte growth and development factor on platelet production and function in nonhuman primates. Blood 1996;88:511-21.
    • (1996) Blood , vol.88 , pp. 511-521
    • Harker, L.A.1    Marzec, U.M.2    Hunt, P.3
  • 21
    • 0029963122 scopus 로고    scopus 로고
    • Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multilineage hematopoietic reconstitution in nonhuman primates after radiation-induced marrow aplasia
    • Farese AM, Hunt P, Grab LB, MacVittie TJ. Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multilineage hematopoietic reconstitution in nonhuman primates after radiation-induced marrow aplasia. J Clin Invest 1996;97:2145-51.
    • (1996) J Clin Invest , vol.97 , pp. 2145-2151
    • Farese, A.M.1    Hunt, P.2    Grab, L.B.3    MacVittie, T.J.4
  • 22
    • 0029999474 scopus 로고    scopus 로고
    • Megakaryocyte growth and development factor accelerates platelet recovery in peripheral blood progenitor cell transplant recipients
    • Molineux G, Hartley C, McElroy P, McCrea C, McNiece IK. Megakaryocyte growth and development factor accelerates platelet recovery in peripheral blood progenitor cell transplant recipients. Blood 1996;88:366-76.
    • (1996) Blood , vol.88 , pp. 366-376
    • Molineux, G.1    Hartley, C.2    McElroy, P.3    McCrea, C.4    McNiece, I.K.5
  • 23
    • 0029839244 scopus 로고    scopus 로고
    • Megakaryocyte growth and development factor stimulates enhanced platelet recovery in mice after bone marrow transplantation
    • Idem. Megakaryocyte growth and development factor stimulates enhanced platelet recovery in mice after bone marrow transplantation. Blood 1996;88:1509-14.
    • (1996) Blood , vol.88 , pp. 1509-1514
    • Molineux, G.1    Hartley, C.2    McElroy, P.3    McCrea, C.4    McNiece, I.K.5
  • 24
    • 0001694426 scopus 로고    scopus 로고
    • The biological significance of truncated and full-length forms of Mpl ligand
    • Kuter DJ, Sheridan WP, Hunt P, Zucker-Franklin D, eds. Totowa, N.J.: Humana Press
    • Foster D, Hunt P. The biological significance of truncated and full-length forms of Mpl ligand. In: Kuter DJ, Sheridan WP, Hunt P, Zucker-Franklin D, eds. Thrombopoiesis and thrombopoietins: molecular, cellular, preclinical and clinical biology. Totowa, N.J.: Humana Press, 1996:203-14.
    • (1996) Thrombopoiesis and Thrombopoietins: Molecular, Cellular, Preclinical and Clinical Biology , pp. 203-214
    • Foster, D.1    Hunt, P.2
  • 25
    • 0029098178 scopus 로고
    • Paclitaxel and carboplatin in combination in the treatment of advanced non-small-cell lung cancer: A phase II toxicity, response, and survival analysis
    • Langer CJ, Leighton JC, Comis RL, et al. Paclitaxel and carboplatin in combination in the treatment of advanced non-small-cell lung cancer: a phase II toxicity, response, and survival analysis. J Clin Oncol 1995;13: 1860-70.
    • (1995) J Clin Oncol , vol.13 , pp. 1860-1870
    • Langer, C.J.1    Leighton, J.C.2    Comis, R.L.3
  • 26
    • 0029059645 scopus 로고
    • Phase I study of paclitaxel as a 3-hour infusion followed by carboplatin in untreated patients with stage IV non-small cell lung cancer
    • Rowinsky EK, Flood WA, Sartorius SE, Bowling MK, Wagner J, Ettinger DS. Phase I study of paclitaxel as a 3-hour infusion followed by carboplatin in untreated patients with stage IV non-small cell lung cancer. Scmin Oncol 1995;22:Suppl 9:48-54
    • (1995) Scmin Oncol , vol.22 , Issue.9 SUPPL. , pp. 48-54
    • Rowinsky, E.K.1    Flood, W.A.2    Sartorius, S.E.3    Bowling, M.K.4    Wagner, J.5    Ettinger, D.S.6
  • 27
    • 0024440650 scopus 로고
    • Carboplatin dosage: Prospective evaluation of a simple formula based on renal function
    • Calvert AH, Newell DR, Gumbrell LA, et al. Carboplatin dosage: prospective evaluation of a simple formula based on renal function. J Clin Oncol 1989;7:1748-56.
    • (1989) J Clin Oncol , vol.7 , pp. 1748-1756
    • Calvert, A.H.1    Newell, D.R.2    Gumbrell, L.A.3
  • 30
    • 0003119275 scopus 로고
    • Lung
    • Abeloff MD, Armitage JO, Lichter AS, Niederhuber JE, eds. New York: Churchill Livingstone
    • Feld R, Ginsberg RJ, Payne DG, Shepherd FA. Lung. In: Abeloff MD, Armitage JO, Lichter AS, Niederhuber JE, eds. Clinical oncology. New York: Churchill Livingstone, 1995:1083-152.
    • (1995) Clinical Oncology , pp. 1083-1152
    • Feld, R.1    Ginsberg, R.J.2    Payne, D.G.3    Shepherd, F.A.4
  • 31
    • 0027469684 scopus 로고
    • The effects of treatment with interleukin-1α on platelet recovery after high-dose carboplatin
    • Smith JW II, Longo DL, Alvord WG, et al. The effects of treatment with interleukin-1α on platelet recovery after high-dose carboplatin. N Engl J Med 1993;328:756-61.
    • (1993) N Engl J Med , vol.328 , pp. 756-761
    • Smith II, J.W.1    Longo, D.L.2    Alvord, W.G.3
  • 32
    • 0026728713 scopus 로고
    • Effects of recombinant human interleukin-3 in patients with relapsed small-cell lung cancer treated with chemotherapy: A dose-finding study
    • Postmus PE, Gietema JA, Damsma O, et al. Effects of recombinant human interleukin-3 in patients with relapsed small-cell lung cancer treated with chemotherapy: a dose-finding study. J Clin Oncol 1992;10:1131-40.
    • (1992) J Clin Oncol , vol.10 , pp. 1131-1140
    • Postmus, P.E.1    Gietema, J.A.2    Damsma, O.3
  • 33
    • 0028961058 scopus 로고
    • Thrombopoietic effects and toxicity of interleukin-6 in patients with ovarian cancer before and after chemotherapy: Multicentric placebo-controlled, randomized phase Ib study
    • D'Hondt V, Humblet Y, Guillaume T, et al. Thrombopoietic effects and toxicity of interleukin-6 in patients with ovarian cancer before and after chemotherapy: multicentric placebo-controlled, randomized phase Ib study. Blood 1995;85:2347-53.
    • (1995) Blood , vol.85 , pp. 2347-2353
    • D'Hondt, V.1    Humblet, Y.2    Guillaume, T.3
  • 34
    • 15844395460 scopus 로고    scopus 로고
    • A phase I trial of recombinant human interleukin-11 (neumega rhIL-11 growth factor) in women with breast cancer receiving chemotherapy
    • Gordon MS, McCaskill-Stevens WJ, Battiato LA, et al. A phase I trial of recombinant human interleukin-11 (neumega rhIL-11 growth factor) in women with breast cancer receiving chemotherapy. Blood 1996;87:3615-24.
    • (1996) Blood , vol.87 , pp. 3615-3624
    • Gordon, M.S.1    McCaskill-Stevens, W.J.2    Battiato, L.A.3
  • 35
    • 0029118847 scopus 로고
    • In vivo biologic effects of PIXY321, a synthetic hybrid protein of recombinant human granulocyte-macrophage colony-stimulating factor and interleukin-3 in cancer patients with normal hematopoiesis: A phase I study
    • Vadhan-Raj S, Broxmeyer HE, Andreeff M, et al. In vivo biologic effects of PIXY321, a synthetic hybrid protein of recombinant human granulocyte-macrophage colony-stimulating factor and interleukin-3 in cancer patients with normal hematopoiesis: a phase I study. Blood 1995;86:2098-105.
    • (1995) Blood , vol.86 , pp. 2098-2105
    • Vadhan-Raj, S.1    Broxmeyer, H.E.2    Andreeff, M.3
  • 36
    • 0027006423 scopus 로고
    • Coagulation abnormalities in malignancy: A review
    • Bick RL. Coagulation abnormalities in malignancy: a review. Semin Thromb Hemost 1992;18:353-72.
    • (1992) Semin Thromb Hemost , vol.18 , pp. 353-372
    • Bick, R.L.1
  • 37
    • 0023872584 scopus 로고
    • Chemotherapy for breast cancer decreases plasma protein C and protein S
    • Rogers JS II, Murgo AJ, Fontana JA, Raich PC. Chemotherapy for breast cancer decreases plasma protein C and protein S. J Clin Oncol 1988; 6:276-81.
    • (1988) J Clin Oncol , vol.6 , pp. 276-281
    • Rogers II, J.S.1    Murgo, A.J.2    Fontana, J.A.3    Raich, P.C.4
  • 38
    • 10344235968 scopus 로고    scopus 로고
    • Thrombopoietic effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in patients with advanced cancer
    • Basser RL, Rasko JEJ, Clarke K, et al. Thrombopoietic effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in patients with advanced cancer. Lancet 1996;348: 1279-81.
    • (1996) Lancet , vol.348 , pp. 1279-1281
    • Basser, R.L.1    Rasko, J.E.J.2    Clarke, K.3
  • 39
    • 10344238601 scopus 로고    scopus 로고
    • Administration of pegylated recombinant human megakaryocyte growth and development factor to humans stimulates the production of functional platelets that show no evidence of in vivo activation
    • O'Malley CJ, Rasko JEJ, Basser RL, et al. Administration of pegylated recombinant human megakaryocyte growth and development factor to humans stimulates the production of functional platelets that show no evidence of in vivo activation. Blood 1996;88:3288-98.
    • (1996) Blood , vol.88 , pp. 3288-3298
    • O'Malley, C.J.1    Rasko, J.E.J.2    Basser, R.L.3
  • 40
    • 0028827190 scopus 로고
    • Thrombopoietin, c-Mpl ligand, induces tyrosine phosphorylation of Tyk2, JAK2, and STAT3, and enhances agonists-induced aggregation in platelets in vitro
    • Ezumi Y, Takayama H, Okuma M. Thrombopoietin, c-Mpl ligand, induces tyrosine phosphorylation of Tyk2, JAK2, and STAT3, and enhances agonists-induced aggregation in platelets in vitro. FEBS Lett 1995;374:48-52.
    • (1995) FEBS Lett , vol.374 , pp. 48-52
    • Ezumi, Y.1    Takayama, H.2    Okuma, M.3
  • 41
    • 0029080417 scopus 로고
    • Megakaryocyte growth and development factor (MGDF) moderately enhances in-vitro platelet aggregation
    • Toombs CF, Young CH, Glaspy JA, Varnum BC. Megakaryocyte growth and development factor (MGDF) moderately enhances in-vitro platelet aggregation. Thromb Res 1995;80:23-33.
    • (1995) Thromb Res , vol.80 , pp. 23-33
    • Toombs, C.F.1    Young, C.H.2    Glaspy, J.A.3    Varnum, B.C.4
  • 42
    • 0028820319 scopus 로고
    • Regulation of platelet activation in vitro by the c-Mpl ligand, thrombopoietin
    • Chen J, Herceg-Harjacek L, Groopman JE, Grabarck J. Regulation of platelet activation in vitro by the c-Mpl ligand, thrombopoietin. Blood 1995;86:4054-62.
    • (1995) Blood , vol.86 , pp. 4054-4062
    • Chen, J.1    Herceg-Harjacek, L.2    Groopman, J.E.3    Grabarck, J.4
  • 43
    • 0027207172 scopus 로고
    • Identification of a functional receptor for granulocyte colony-stimulating factor on platelets
    • Shimoda K, Okamura S, Harada N, Kondo S, Okamura T, Niho Y. Identification of a functional receptor for granulocyte colony-stimulating factor on platelets. J Clin Invest 1993;91:1310-3.
    • (1993) J Clin Invest , vol.91 , pp. 1310-1313
    • Shimoda, K.1    Okamura, S.2    Harada, N.3    Kondo, S.4    Okamura, T.5    Niho, Y.6
  • 44
    • 0028168839 scopus 로고
    • Human kit ligand (stem cell factor) modulates platelet activation in vitro
    • Grabarek J, Groopman JE, Lyles YR, et al. Human kit ligand (stem cell factor) modulates platelet activation in vitro. J Biol Chem 1994;269: 21718-24.
    • (1994) J Biol Chem , vol.269 , pp. 21718-21724
    • Grabarek, J.1    Groopman, J.E.2    Lyles, Y.R.3
  • 45
    • 0009723930 scopus 로고
    • Safety profile of filgrastim (r-metHuG-CSF)
    • Morstyn G, Dexter TM, eds. New York: Marcel Dekker
    • Decoster G, Rich W, Brown SL. Safety profile of filgrastim (r-metHuG-CSF). In: Morstyn G, Dexter TM, eds. Filgrastim (r-metHuG-CSF) in clinical practice. New York: Marcel Dekker, 1994:267-90.
    • (1994) Filgrastim (R-metHuG-CSF) in Clinical Practice , pp. 267-290
    • Decoster, G.1    Rich, W.2    Brown, S.L.3
  • 46
    • 0029947810 scopus 로고    scopus 로고
    • Clinical applications of stem cell factor
    • Glaspy J. Clinical applications of stem cell factor. Curr Opin Hematol 1996;3:223-9.
    • (1996) Curr Opin Hematol , vol.3 , pp. 223-229
    • Glaspy, J.1


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