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Volumn 11, Issue 2, 1998, Pages 141-148

New drugs for epilepsy

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; FELBAMATE; GABAPENTIN; LAMOTRIGINE; OXCARBAZEPINE; PLACEBO; TIAGABINE; TOPIRAMATE; VIGABATRIN; ZONISAMIDE;

EID: 0031942097     PISSN: 13507540     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019052-199804000-00011     Document Type: Review
Times cited : (30)

References (86)
  • 1
    • 0029978025 scopus 로고    scopus 로고
    • The impact of new antiepileptic drugs on the prognosis of epilepsy: Seizure freedom should be the ultimate goal
    • Walker MC, Sander JW. The impact of new antiepileptic drugs on the prognosis of epilepsy: seizure freedom should be the ultimate goal. Neurology 1996; 46:912-914.
    • (1996) Neurology , vol.46 , pp. 912-914
    • Walker, M.C.1    Sander, J.W.2
  • 2
    • 0029742812 scopus 로고    scopus 로고
    • The new antiepileptic drugs: Their current role in the management of epilepsy
    • Sander JW. The new antiepileptic drugs: their current role in the management of epilepsy. Eur J Neurol 1996; 3 (Suppl 3):15-20.
    • (1996) Eur J Neurol , vol.3 , Issue.3 SUPPL. , pp. 15-20
    • Sander, J.W.1
  • 3
    • 0027137896 scopus 로고
    • Some aspects of the prognosis of the epilepsies: A review
    • Sander JW. Some aspects of the prognosis of the epilepsies: a review. Epilepsia 1993; 34:1007-1016.
    • (1993) Epilepsia , vol.34 , pp. 1007-1016
    • Sander, J.W.1
  • 4
    • 0030823963 scopus 로고    scopus 로고
    • How rational is current antiepileptic drug treatment?
    • Paris
    • O'Donoghue MF, Sander JW. How rational is current antiepileptic drug treatment? Rev Neurol (Paris) 1997; 153 (Suppl 1):25-28.
    • (1997) Rev Neurol , vol.153 , Issue.1 SUPPL. , pp. 25-28
    • O'Donoghue, M.F.1    Sander, J.W.2
  • 5
    • 0029762193 scopus 로고    scopus 로고
    • Polytherapy revisited
    • Reynolds EH. Polytherapy revisited. Eur J Neurol 1996; 3 (Suppl 3):9-13.
    • (1996) Eur J Neurol , vol.3 , Issue.3 SUPPL. , pp. 9-13
    • Reynolds, E.H.1
  • 6
    • 0029822510 scopus 로고    scopus 로고
    • New antiepileptic drugs: A systematic review of their efficacy and tolerability
    • Marson AG, Kadir ZA, Chadwick DW. New antiepileptic drugs: a systematic review of their efficacy and tolerability. Br Med J 1996; 313:1169-1174. This is an interesting meta-analysis of all randomized placebo-controlled clinical trials of the tolerability and efficacy measured in terms of 50% seizure reduction of the new AEDs gabapentin, lamotrigine, tiagabine, topiramate. vigabatrin and zonisamide in patients with refractory partial epilepsy. No difference was established between the drugs.
    • (1996) Br Med J , vol.313 , pp. 1169-1174
    • Marson, A.G.1    Kadir, Z.A.2    Chadwick, D.W.3
  • 7
    • 0029827521 scopus 로고    scopus 로고
    • Clinical administration of new antiepileptic drugs: An overview of safety and efficacy
    • Chadwick DW, Marson T, Kadir Z. Clinical administration of new antiepileptic drugs: an overview of safety and efficacy. Epilepsia 1996; 37 (Suppl 6):S17-S22
    • (1996) Epilepsia , vol.37 , Issue.6 SUPPL.
    • Chadwick, D.W.1    Marson, T.2    Kadir, Z.3
  • 8
    • 0030951771 scopus 로고    scopus 로고
    • Clinical significance of animal seizure models and mechanism of action studies of potential antiepileptic drugs
    • White HS. Clinical significance of animal seizure models and mechanism of action studies of potential antiepileptic drugs. Epilepsia 1997; 38 (Suppl 1):S9-S17.
    • (1997) Epilepsia , vol.38 , Issue.1 SUPPL.
    • White, H.S.1
  • 9
    • 0000658392 scopus 로고    scopus 로고
    • Principles of drug treatment
    • Shorvon SD, Dreifuss F, Fish D, Thomas D (editors): Oxford: Blackwell
    • Perucca E. Principles of drug treatment. In: Shorvon SD, Dreifuss F, Fish D, Thomas D (editors): The treatment of epilepsy. Oxford: Blackwell; 1997. pp. 152-168.
    • (1997) The Treatment of Epilepsy , pp. 152-168
    • Perucca, E.1
  • 10
    • 0028966507 scopus 로고
    • Incidence of sudden unexpected death in an adult outpatient cohort with epilepsy at a tertiary referral centre
    • Nashef L, Fish DR, Sander JW, Shorvon SD, Incidence of sudden unexpected death in an adult outpatient cohort with epilepsy at a tertiary referral centre. J Neurol Neurosurg Psychiatry 1995; 58:462-464.
    • (1995) J Neurol Neurosurg Psychiatry , vol.58 , pp. 462-464
    • Nashef, L.1    Fish, D.R.2    Sander, J.W.3    Shorvon, S.D.4
  • 11
    • 0031026814 scopus 로고    scopus 로고
    • Sudden unexplained death in epilepsy: Observations from a large clinical development program
    • Leestma JE, Annegers JF, Brodie MJ, Brown S, Schraeder P, Siscovick D, et al. Sudden unexplained death in epilepsy: observations from a large clinical development program. Epilepsia 1997; 38:47-55. A study of the rate of sudden death in patients included in lamotrigine clinical trials is presented. Lamotrigine does not seem to influence this rate.
    • (1997) Epilepsia , vol.38 , pp. 47-55
    • Leestma, J.E.1    Annegers, J.F.2    Brodie, M.J.3    Brown, S.4    Schraeder, P.5    Siscovick, D.6
  • 12
    • 0029850036 scopus 로고    scopus 로고
    • Epilepsy and sudden death
    • Nashef L, Brown S. Epilepsy and sudden death. Lancet 1996; 348:1324-1325.
    • (1996) Lancet , vol.348 , pp. 1324-1325
    • Nashef, L.1    Brown, S.2
  • 13
    • 0030577195 scopus 로고    scopus 로고
    • Long-term use of lamotrigine and vigabatrin in severe refractory epilepsy: Audit of outcome
    • Walker MC, Li LM, Sander JW. Long-term use of lamotrigine and vigabatrin in severe refractory epilepsy: audit of outcome. Br Med J 1996; 313:1184-1185. This paper outlines an audit of the long-term outcome in terms of seizure freedom and mortality of patients with chronic partial epilepsy recruited into early studies of the new AEDs vigabatrin and lamotrigine. These drugs had little impact in the long-term prognosis of these patients.
    • (1996) Br Med J , vol.313 , pp. 1184-1185
    • Walker, M.C.1    Li, L.M.2    Sander, J.W.3
  • 14
    • 0028359051 scopus 로고
    • Newer antiepileptic drugs: Towards an improved risk-benefit ratio
    • Patsalos PN, Sander JW. Newer antiepileptic drugs: towards an improved risk-benefit ratio. Drug Safety 1994; 11:37-67.
    • (1994) Drug Safety , vol.11 , pp. 37-67
    • Patsalos, P.N.1    Sander, J.W.2
  • 15
    • 0028390776 scopus 로고
    • New antiepileptic drugs
    • Chadwick D. New antiepileptic drugs. Q J Med 1994; 87:139-141.
    • (1994) Q J Med , vol.87 , pp. 139-141
    • Chadwick, D.1
  • 17
    • 0029794327 scopus 로고    scopus 로고
    • Influence of vigabatrin on cognitive performances and behaviour in patients with drug-resistant epilepsy
    • Provinciali L, Bartolini M, Mari F, Del-Pesce M, Ceravolo MG. Influence of vigabatrin on cognitive performances and behaviour in patients with drug-resistant epilepsy. Acta Neurol Scand 1996; 94:12-18.
    • (1996) Acta Neurol Scand , vol.94 , pp. 12-18
    • Provinciali, L.1    Bartolini, M.2    Mari, F.3    Del-Pesce, M.4    Ceravolo, M.G.5
  • 19
    • 0029145978 scopus 로고
    • Taming the brain storms: Felbamate updated
    • Brodie MJ, Pellock JM. Taming the brain storms: felbamate updated. Lancet 1995; 346:918-919.
    • (1995) Lancet , vol.346 , pp. 918-919
    • Brodie, M.J.1    Pellock, J.M.2
  • 22
    • 0029619760 scopus 로고
    • Adverse effects of established and new antiepileptic drugs: An attempted comparison
    • Rogvi-Hansen B, Gram L. Adverse effects of established and new antiepileptic drugs: an attempted comparison. Pharmacol Ther 1995; 68:425-434.
    • (1995) Pharmacol Ther , vol.68 , pp. 425-434
    • Rogvi-Hansen, B.1    Gram, L.2
  • 23
    • 0029833566 scopus 로고    scopus 로고
    • Vigabatrin
    • Guberman A, Vigabatrin. Can J Neurol Sci 1996; 23 (Suppl 4):S13-S17.
    • (1996) Can J Neurol Sci , vol.23 , Issue.4 SUPPL.
    • Guberman, A.1
  • 24
    • 0029826744 scopus 로고    scopus 로고
    • The new generation of antiepileptic drugs: Advantages and disadvantages
    • Perucca E. The new generation of antiepileptic drugs: advantages and disadvantages. Br J Clin Pharmacol 1996; 42:531-543. A good review of the efficacy, tolerability and pharmacokinetics of all newly marketed AEDs is presented.
    • (1996) Br J Clin Pharmacol , vol.42 , pp. 531-543
    • Perucca, E.1
  • 25
    • 0030994201 scopus 로고    scopus 로고
    • Effect of topiramate on attention
    • Burton LA, Harden C. Effect of topiramate on attention. Epilepsy Res 1997; 27:29-32.
    • (1997) Epilepsy Res , vol.27 , pp. 29-32
    • Burton, L.A.1    Harden, C.2
  • 26
    • 0029002590 scopus 로고
    • Felbamate
    • Leppik I. Felbamate. Epilepsia 1995; 36 (Suppl 2):S66-S72.
    • (1995) Epilepsia , vol.36 , Issue.2 SUPPL.
    • Leppik, I.1
  • 29
    • 0030832143 scopus 로고    scopus 로고
    • Serious dermatologic reactions in children
    • Knowles S, Shapiro L, Shear-NH Serious dermatologic reactions in children. Curr Opin Pediatr 1997; 9:388-395. This paper provides an interesting review of lamotrigine-induced toxic epidermal necrolysis and Stevens-Johnson syndrome.
    • (1997) Curr Opin Pediatr , vol.9 , pp. 388-395
    • Knowles, S.1    Shapiro, L.2    Shear, N.H.3
  • 30
  • 31
    • 17944392706 scopus 로고    scopus 로고
    • Epilepsy drug exhibits fatal side effects
    • Anon. Epilepsy drug exhibits fatal side effects. Nat Biotechnol 1997; 15:398.
    • (1997) Nat Biotechnol , vol.15 , pp. 398
  • 32
    • 0029807158 scopus 로고    scopus 로고
    • The new antiepileptic drugs and women: Efficacy, reproductive health, pregnancy, and fetal outcome
    • Morrell MJ. The new antiepileptic drugs and women: efficacy, reproductive health, pregnancy, and fetal outcome. Epilepsia 1996; 37 (Suppl 6):S34-S44. A good review is presented of the impact of the new AED on reproductive health.
    • (1996) Epilepsia , vol.37 , Issue.6 SUPPL.
    • Morrell, M.J.1
  • 33
    • 0031015788 scopus 로고    scopus 로고
    • Severe persistent visual field constriction associated with vigabatrin
    • Eke T, Talbot JF, Lawden MC. Severe persistent visual field constriction associated with vigabatrin. Br Med J 1997; 314:180-181. This is the first report of a potential chronic side-effect of a new AED.
    • (1997) Br Med J , vol.314 , pp. 180-181
    • Eke, T.1    Talbot, J.F.2    Lawden, M.C.3
  • 34
    • 0029803697 scopus 로고    scopus 로고
    • Pharmacokinetics of new antiepileptic drugs
    • Gram L. Pharmacokinetics of new antiepileptic drugs. Epilepsia 1996; 37 (Suppl 6):S12-S16.
    • (1996) Epilepsia , vol.37 , Issue.6 SUPPL.
    • Gram, L.1
  • 35
    • 0029841727 scopus 로고    scopus 로고
    • Pharmacokinetic interactions between antiepileptic drugs. Clinical considerations
    • Riva R, Albani F, Contin M, Baruzzi A. Pharmacokinetic interactions between antiepileptic drugs. Clinical considerations. Clin Pharmacokinet 1996; 31:470-493.
    • (1996) Clin Pharmacokinet , vol.31 , pp. 470-493
    • Riva, R.1    Albani, F.2    Contin, M.3    Baruzzi, A.4
  • 36
    • 0029887507 scopus 로고    scopus 로고
    • The clinical pharmacokinetics of the newer antiepileptic drugs. Focus on topiramate, zonisamide and tiagabine
    • Perucca E, Bialer M. The clinical pharmacokinetics of the newer antiepileptic drugs. Focus on topiramate, zonisamide and tiagabine. Clin Pharmacokinet 1996; 31:29-46.
    • (1996) Clin Pharmacokinet , vol.31 , pp. 29-46
    • Perucca, E.1    Bialer, M.2
  • 37
    • 0030754395 scopus 로고    scopus 로고
    • Difficulties in extrapolating from clinical trial data to clinical practice: The case of antiepileptic drugs
    • Walker MC, Sander JW. Difficulties in extrapolating from clinical trial data to clinical practice: the case of antiepileptic drugs. Neurology 1997; 49:333-337. This is an interesting discussion of the role and shortcomings of meta-analysis of controlled trials of AEDs using 50% seizure reduction as the measure of efficacy. It is argued that new AED trials can determine appropriate use of AEDs but fail to determine their exact role in treating patients. The need for large multicenter studies in well defined populations with well characterized epilepsy syndromes and aetiologies, using seizure freedom as the primary measure of efficacy is emphasized.
    • (1997) Neurology , vol.49 , pp. 333-337
    • Walker, M.C.1    Sander, J.W.2
  • 38
    • 0028129672 scopus 로고
    • The cost of epilepsy in the United Kingdom: An estimation based on the results of two population-based studies
    • Cockerell OC, Hart YM, Sander JWAS, Shorvon SD. The cost of epilepsy in the United Kingdom: an estimation based on the results of two population-based studies. Epilepsy Res 1994; 18:249-260.
    • (1994) Epilepsy Res , vol.18 , pp. 249-260
    • Cockerell, O.C.1    Hart, Y.M.2    Jwas, S.3    Shorvon, S.D.4
  • 39
    • 0030297531 scopus 로고    scopus 로고
    • Cost analysis of epilepsy surgery and of vigabatrin treatment in patients with refractory partial epilepsy
    • Malmgren K, Hedstrom A, Granqvist R, Malmgren H, Ben-Menachem-E. Cost analysis of epilepsy surgery and of vigabatrin treatment in patients with refractory partial epilepsy. Epilepsy Res 1996; 25:199-207.
    • (1996) Epilepsy Res , vol.25 , pp. 199-207
    • Malmgren, K.1    Hedstrom, A.2    Granqvist, R.3    Malmgren, H.4    Ben-Menachem-E5
  • 40
    • 0029651761 scopus 로고
    • Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy
    • Brodie MJ, Richens A, Yuen AW. Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy. Lancet 1995; 345:476-479. This comparative trial between an established AED, carbamazepine, and the new AED lamotrigine failed to show any difference in terms of efficacy.
    • (1995) Lancet , vol.345 , pp. 476-479
    • Brodie, M.J.1    Richens, A.2    Yuen, A.W.3
  • 41
    • 0029143292 scopus 로고
    • Vigabatrin vs carbamazepine monotherapy in patients with newly diagnosed epilepsy. A randomized, controlled study
    • Kalviainen R, Aikia M, Saukkonen AM, Mervaala E, Riekkinen P. Vigabatrin vs carbamazepine monotherapy in patients with newly diagnosed epilepsy. A randomized, controlled study. Arch-Neurol 1995; 52:989-996. This comparative trial between an established AED, carbamazepine, and the new AED vigabatrin suggests that carbamazepine is better in terms of rendering patients seizure free.
    • (1995) Arch-Neurol , vol.52 , pp. 989-996
    • Kalviainen, R.1    Aikia, M.2    Saukkonen, A.M.3    Mervaala, E.4    Riekkinen, P.5
  • 42
    • 0030297101 scopus 로고    scopus 로고
    • Vigabatrin vs. carbamazepine monotherapy in newly diagnosed focal epilepsy: A randomized response conditional crossover study
    • Tanganelli P, Regesta G. Vigabatrin vs. carbamazepine monotherapy in newly diagnosed focal epilepsy: a randomized response conditional crossover study. Epilepsy Res 1996; 25:257-262. This comparative trial between an established AED, carbamazepine, and the new AED vigabatrin failed to show any difference between the drugs in terms of efficacy.
    • (1996) Epilepsy Res , vol.25 , pp. 257-262
    • Tanganelli, P.1    Regesta, G.2
  • 43
    • 0030796901 scopus 로고    scopus 로고
    • A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in children and adolescents with epilepsy
    • Guerreiro MM, Vigonius U, Pohlmann H, de-Manreza ML, Fejerman N, Antoniuk SA, Moore A. A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in children and adolescents with epilepsy. Epilepsy Res 1997; 27:205-213. This comparative trial between an established AED, phenytoin, and the new AED oxcarbazepine failed to show any difference between the drugs in terms of efficacy.
    • (1997) Epilepsy Res , vol.27 , pp. 205-213
    • Guerreiro, M.M.1    Vigonius, U.2    Pohlmann, H.3    De-Manreza, M.L.4    Fejerman, N.5    Antoniuk, S.A.6    Moore, A.7
  • 44
    • 0030805745 scopus 로고    scopus 로고
    • A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in adults with previously untreated epilepsy
    • Bill PA, Vigonius U, Pohlmann H, Guerreiro CA, Kochen S, Saffer D, Moore A. A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in adults with previously untreated epilepsy. Epilepsy Res 1997; 27:195-204. Another comparative trial between an established AED, phenytoin, and the new AED oxcarbazepine failed to show any difference between the drugs in terms of efficacy.
    • (1997) Epilepsy Res , vol.27 , pp. 195-204
    • Bill, P.A.1    Vigonius, U.2    Pohlmann, H.3    Guerreiro, C.A.4    Kochen, S.5    Saffer, D.6    Moore, A.7
  • 45
    • 0343247768 scopus 로고    scopus 로고
    • A double-blind controlled clinical trial: Oxcarbazepine versus sodium valproate in adults with newly diagnosed epilepsy
    • Christe W, Kramer G, Vigonius U, Pohlmann H, Steinhoff BJ, Brodie MJ, Moore A. A double-blind controlled clinical trial: oxcarbazepine versus sodium valproate in adults with newly diagnosed epilepsy. Epilepsy Res 1997; 26:451-460. This comparative trial between an established AED, valproate, and the new AED oxcarbazepine failed to show any difference between the drugs in terms of efficacy.
    • (1997) Epilepsy Res , vol.26 , pp. 451-460
    • Christe, W.1    Kramer, G.2    Vigonius, U.3    Pohlmann, H.4    Steinhoff, B.J.5    Brodie, M.J.6    Moore, A.7
  • 46
    • 0030948885 scopus 로고    scopus 로고
    • What trials, which designs?
    • French JA. What trials, which designs? Epilepsia. 1997; 38:263-265. An interesting comment is made on the design of clinical trials for AEDs.
    • (1997) Epilepsia , vol.38 , pp. 263-265
    • French, J.A.1
  • 47
    • 33646836642 scopus 로고    scopus 로고
    • Drug trials in epilepsy
    • Mignot G. Drug trials in epilepsy. Br Med J 1996; 313:1158.
    • (1996) Br Med J , vol.313 , pp. 1158
    • Mignot, G.1
  • 48
    • 0030292466 scopus 로고    scopus 로고
    • Epileptic syndromes: An underutilized concept
    • Benbadis SR, Luders HO. Epileptic syndromes: an underutilized concept. Epilepsia 1996; 37:1029-1034.
    • (1996) Epilepsia , vol.37 , pp. 1029-1034
    • Benbadis, S.R.1    Luders, H.O.2
  • 50
    • 0029831493 scopus 로고    scopus 로고
    • Update on the mechanism of action of antiepileptic drugs
    • Meldrum BS. Update on the mechanism of action of antiepileptic drugs. Epilepsia 1996; 37 (Suppl 6):S4-S11.
    • (1996) Epilepsia , vol.37 , Issue.6 SUPPL.
    • Meldrum, B.S.1
  • 51
    • 0030959522 scopus 로고    scopus 로고
    • Mechanisms of action of new antiepileptic drugs
    • Macdonald RL, Greenfield LJ. Mechanisms of action of new antiepileptic drugs. Curr Opin Neurol 1997; 10:121-128.
    • (1997) Curr Opin Neurol , vol.10 , pp. 121-128
    • Macdonald, R.L.1    Greenfield, L.J.2
  • 53
    • 0029805213 scopus 로고    scopus 로고
    • Felbamate in therapy-resistant epilepsy: An Italian experience. Felbamate Italian Study Group
    • Avanzini G, Canger R, Dalla-Bernardina B, Vigevano F. Felbamate in therapy-resistant epilepsy: an Italian experience. Felbamate Italian Study Group. Epilepsy Res 1996; 25:249-255.
    • (1996) Epilepsy Res , vol.25 , pp. 249-255
    • Avanzini, G.1    Canger, R.2    Dalla-Bernardina, B.3    Vigevano, F.4
  • 54
    • 0029851925 scopus 로고    scopus 로고
    • Gabapentin
    • Bruni J. Gabapentin. Can J Neurol Sci 1996; 23 (4S):S3-S5.
    • (1996) Can J Neurol Sci , vol.23 , Issue.4 S
    • Bruni, J.1
  • 56
    • 0030776298 scopus 로고    scopus 로고
    • Gabapentin monotherapy: II. A 26-week, double-blind, dose-controlled, multicenter study of conversion from polytherapy in outpatients with refractory complex partial or secondarily generalized seizures
    • •] outline two trials that provide some support for the use of gabapentin as monotherapy in some patients with chronic partial epilepsy.
    • (1997) Neurology , vol.49 , pp. 746-752
    • Beydoun, A.1    Fischer, J.2    Labar, D.R.3    Harden, C.4    Cantrell, D.5    Uthman, B.M.6
  • 59
    • 0030940881 scopus 로고    scopus 로고
    • Gabapentin and cognition: A double blind, dose ranging, placebo controlled study in refractory epilepsy
    • Leach JP, Girvan J, Paul A, Brodie MJ. Gabapentin and cognition: a double blind, dose ranging, placebo controlled study in refractory epilepsy. J Neurol Neurosurg Psychiatry 1997; 62:372-376. This trial suggest that gabapentin has no measurable effect on cognition but that it produces sedation at high doses.
    • (1997) J Neurol Neurosurg Psychiatry , vol.62 , pp. 372-376
    • Leach, J.P.1    Girvan, J.2    Paul, A.3    Brodie, M.J.4
  • 61
    • 0027094188 scopus 로고
    • Lamotrigine as an add-on drug in the management of Lennox-Gastaut syndrome
    • Timmings PL, Richens A. Lamotrigine as an add-on drug in the management of Lennox-Gastaut syndrome. Eur Neurol 1992; 32:305-307.
    • (1992) Eur Neurol , vol.32 , pp. 305-307
    • Timmings, P.L.1    Richens, A.2
  • 62
    • 0031028879 scopus 로고    scopus 로고
    • Lamotrigine adjunctive therapy in childhood epileptic encephalopathy (the Lennox Gastaut syndrome)
    • Donaldson JA, Glauser TA, Olberding LS. Lamotrigine adjunctive therapy in childhood epileptic encephalopathy (the Lennox Gastaut syndrome). Epilepsia 1997; 38:68-73.
    • (1997) Epilepsia , vol.38 , pp. 68-73
    • Donaldson, J.A.1    Glauser, T.A.2    Olberding, L.S.3
  • 63
    • 0026597799 scopus 로고
    • Lamotrigine-induced carbamazepine toxicity: An interaction with carbamazepine-10,11-epoxide
    • Warner T, Patsalos PN, Prevett M, Elyas AA, Duncan JS. Lamotrigine-induced carbamazepine toxicity: an interaction with carbamazepine-10,11-epoxide. Epilepsy Res 1992; 11:147-150.
    • (1992) Epilepsy Res , vol.11 , pp. 147-150
    • Warner, T.1    Patsalos, P.N.2    Prevett, M.3    Elyas, A.A.4    Duncan, J.S.5
  • 64
    • 0028825851 scopus 로고
    • Clinical pharmacokinetics of new antiepileptic drugs
    • Walker MC, Patsalos PN. Clinical pharmacokinetics of new antiepileptic drugs. Pharmacol Ther 1995; 67:351-384.
    • (1995) Pharmacol Ther , vol.67 , pp. 351-384
    • Walker, M.C.1    Patsalos, P.N.2
  • 65
    • 0029816665 scopus 로고    scopus 로고
    • Pharmacokinetic interactions between lamotrigine and other antiepileptic drugs in children with intractable epilepsy
    • Eriksson AS, Hoppu K, Nergardh A, Boreus L. Pharmacokinetic interactions between lamotrigine and other antiepileptic drugs in children with intractable epilepsy. Epilepsia 1996; 37:769-773.
    • (1996) Epilepsia , vol.37 , pp. 769-773
    • Eriksson, A.S.1    Hoppu, K.2    Nergardh, A.3    Boreus, L.4
  • 66
  • 67
    • 0001997804 scopus 로고    scopus 로고
    • Oxcarbazepine
    • Engel J, Pedley TA (editors): New York: Lippincott-Raven
    • Gram L. Oxcarbazepine. In: Engel J, Pedley TA (editors): Epilepsy: a comprehensive textbook. New York: Lippincott-Raven; 1997. pp. 1541-1546.
    • (1997) Epilepsy: A Comprehensive Textbook , pp. 1541-1546
    • Gram, L.1
  • 68
    • 0028360220 scopus 로고
    • A double-blind, placebo-controlled interaction study between oxcarbazepine and carbamazepine, sodium valproate and phenytoin in epileptic patients
    • McKee PJ, Blacklaw J, Forrest G, Gillham R, Walker SM, Connelly D, Brodie MJ. A double-blind, placebo-controlled interaction study between oxcarbazepine and carbamazepine, sodium valproate and phenytoin in epileptic patients. Br J Clin Pharmacol 1994; 37:27-32.
    • (1994) Br J Clin Pharmacol , vol.37 , pp. 27-32
    • McKee, P.J.1    Blacklaw, J.2    Forrest, G.3    Gillham, R.4    Walker, S.M.5    Connelly, D.6    Brodie, M.J.7
  • 69
    • 0028128905 scopus 로고
    • Survey of 260 epileptic patients treated with oxcarbazepine on a named-patient basis
    • Van-Parys JA, Meinardi H. Survey of 260 epileptic patients treated with oxcarbazepine on a named-patient basis. Epilepsy Res 1994; 19:79-85.
    • (1994) Epilepsy Res , vol.19 , pp. 79-85
    • Van-Parys, J.A.1    Meinardi, H.2
  • 72
    • 0030946472 scopus 로고    scopus 로고
    • Cognitive and quality of life effects of differing dosages of tiagabine in epilepsy
    • Dodrill CB, Arnett JL, Sommerville KW, Shu V. Cognitive and quality of life effects of differing dosages of tiagabine in epilepsy. Neurology 1997; 48:1025-1023.
    • (1997) Neurology , vol.48 , pp. 1025-11023
    • Dodrill, C.B.1    Arnett, J.L.2    Sommerville, K.W.3    Shu, V.4
  • 74
    • 0030980625 scopus 로고    scopus 로고
    • Topiramate as adjunctive therapy in refractory partial epilepsy: Pooled analysis of data from five double-blind, placebo-controlled trials
    • Reife RA, Pledger GW. Topiramate as adjunctive therapy in refractory partial epilepsy: pooled analysis of data from five double-blind, placebo-controlled trials. Epilepsia 1997; 38 (Suppl 1):S31-S33. This is the pooled analysis of all placebo-controlled trials of topiramate in patients with partial epilepsy.
    • (1997) Epilepsia , vol.38 , Issue.1 SUPPL.
    • Reife, R.A.1    Pledger, G.W.2
  • 75
    • 0031000085 scopus 로고    scopus 로고
    • Preliminary open-label experience with topiramate in primary generalized seizures
    • Biton V. Preliminary open-label experience with topiramate in primary generalized seizures. Epilepsia 1997; 38 (Suppl 1):S42-S44.
    • (1997) Epilepsia , vol.38 , Issue.1 SUPPL.
    • Biton, V.1
  • 76
    • 0030950105 scopus 로고    scopus 로고
    • Practical aspects of the use of topiramate in patients with epilepsy
    • Sander JW. Practical aspects of the use of topiramate in patients with epilepsy. Epilepsia 1997; 38 (Suppl 1):S56-S58.
    • (1997) Epilepsia , vol.38 , Issue.1 SUPPL.
    • Sander, J.W.1
  • 77
    • 0029845689 scopus 로고    scopus 로고
    • Steady-state pharmacokinetics of topiramate and carbamazepine in patients with epilepsy during monotherapy and concomitant therapy
    • Sachdeo RC, Sachdeo SK, Walker SA, Kramer LD, Nayak RK, Doose DR. Steady-state pharmacokinetics of topiramate and carbamazepine in patients with epilepsy during monotherapy and concomitant therapy. Epilepsia 1996; 37:774-780.
    • (1996) Epilepsia , vol.37 , pp. 774-780
    • Sachdeo, R.C.1    Sachdeo, S.K.2    Walker, S.A.3    Kramer, L.D.4    Nayak, R.K.5    Doose, D.R.6
  • 78
    • 0030956491 scopus 로고    scopus 로고
    • Comparison of the steady-state pharmacokinetics of topiramate and valproate in patients with epilepsy during monotherapy and concomitant therapy
    • Rosenfeld WE, Liao S, Kramer LD, Anderson G, Palmer M, Levy RH, Nayak RK. Comparison of the steady-state pharmacokinetics of topiramate and valproate in patients with epilepsy during monotherapy and concomitant therapy. Epilepsia 1997; 38:324-333.
    • (1997) Epilepsia , vol.38 , pp. 324-333
    • Rosenfeld, W.E.1    Liao, S.2    Kramer, L.D.3    Anderson, G.4    Palmer, M.5    Levy, R.H.6    Nayak, R.K.7
  • 79
    • 0030910546 scopus 로고    scopus 로고
    • Effect of topiramate on the pharmacokinetics of an oral contraceptive containing norethindrone and ethinyl estradiol in patients with epilepsy
    • Rosenfeld WE, Doose DR, Walker S, Nayak RK. Effect of topiramate on the pharmacokinetics of an oral contraceptive containing norethindrone and ethinyl estradiol in patients with epilepsy. Epilepsia 1997; 38:317-323. This is an elegant study that demonstrates the interaction between the contraceptive pill and topiramate.
    • (1997) Epilepsia , vol.38 , pp. 317-323
    • Rosenfeld, W.E.1    Doose, D.R.2    Walker, S.3    Nayak, R.K.4
  • 80
    • 0030931268 scopus 로고    scopus 로고
    • Randomized trial comparing vigabatrin and hydrocortisone in infantile spasms due to tuberous sclerosis
    • Chiron C, Dumas C, Jambaque I, Mumford J, Dulac O. Randomized trial comparing vigabatrin and hydrocortisone in infantile spasms due to tuberous sclerosis. Epilepsy Res 1997; 26:389-395. This study clearly demonstrates that vigabatrin is better than hydrocortisone as a first-choice treatment for infantile spasms due to tuberous sclerosis.
    • (1997) Epilepsy Res , vol.26 , pp. 389-395
    • Chiron, C.1    Dumas, C.2    Jambaque, I.3    Mumford, J.4    Dulac, O.5
  • 81
    • 0026555896 scopus 로고
    • Development of tolerance to the anticonvulsant effect of vigabatrin in amydala-kindled rats
    • Rundfeldt C, Loscher W. Development of tolerance to the anticonvulsant effect of vigabatrin in amydala-kindled rats. Eur J Pharmacol 1992; 213:351-366.
    • (1992) Eur J Pharmacol , vol.213 , pp. 351-366
    • Rundfeldt, C.1    Loscher, W.2
  • 82
    • 0002901048 scopus 로고    scopus 로고
    • Zonisamide
    • Engel J, Pedley TA (editors): New York: Lippincott-Raven
    • Seino M, Ito T. Zonisamide. In: Engel J, Pedley TA (editors): Epilepsy: a comprehensive textbook. New York: Lippincott-Raven; 1997. pp. 1619-1626.
    • (1997) Epilepsy: A Comprehensive Textbook , pp. 1619-1626
    • Seino, M.1    Ito, T.2
  • 83
    • 0029968161 scopus 로고    scopus 로고
    • The effects of antiepileptic drugs on cognition in normal volunteers
    • Akaho R. The effects of antiepileptic drugs on cognition in normal volunteers. Psychiatry Clin Neurosci 1996; 50:61-69.
    • (1996) Psychiatry Clin Neurosci , vol.50 , pp. 61-69
    • Akaho, R.1
  • 84
    • 0029807973 scopus 로고    scopus 로고
    • Preliminary report on teratogenic effects of zonisamide in the offspring of treated women with epilepsy
    • Kondo T, Kaneko S, Amano Y, Egawa I. Preliminary report on teratogenic effects of zonisamide in the offspring of treated women with epilepsy. Epilepsia 1996; 37:1242-1244.
    • (1996) Epilepsia , vol.37 , pp. 1242-1244
    • Kondo, T.1    Kaneko, S.2    Amano, Y.3    Egawa, I.4
  • 85
    • 0029824494 scopus 로고    scopus 로고
    • Vagus nerve stimulation induces a sustained anticonvulsant effect
    • Takaya M, Terry WJ, Naritoku DK. Vagus nerve stimulation induces a sustained anticonvulsant effect. Epilepsia 1996; 37:1111-1116.
    • (1996) Epilepsia , vol.37 , pp. 1111-1116
    • Takaya, M.1    Terry, W.J.2    Naritoku, D.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.