-
1
-
-
10544225751
-
AF12198, a novel low molecular weight antagonist, selectively binds the human type I interleukin (IL)-1 receptor and blocks in vivo responses to IL-1
-
Akeson AL, Woods CW, Hsieh LC, Bohnke RA, Ackermann BL, Chan KY, Robinson JL, Yanofsky SD, Jacob JW, Barrett RW, Bowlin TL (1996) AF12198, a novel low molecular weight antagonist, selectively binds the human type I interleukin (IL)-1 receptor and blocks in vivo responses to IL-1. J Biol Chem 271:30517
-
(1996)
J Biol Chem
, vol.271
, pp. 30517
-
-
Akeson, A.L.1
Woods, C.W.2
Hsieh, L.C.3
Bohnke, R.A.4
Ackermann, B.L.5
Chan, K.Y.6
Robinson, J.L.7
Yanofsky, S.D.8
Jacob, J.W.9
Barrett, R.W.10
Bowlin, T.L.11
-
2
-
-
0027370379
-
Suppression of monocyte function and differential regulation of IL-1 and IL-1Ra by IL-4 contribute to resolution of experimental arthritis
-
Allen JB, Wong HL, Costa GL, Bienkowski MJ, Wahl SM (1993) Suppression of monocyte function and differential regulation of IL-1 and IL-1Ra by IL-4 contribute to resolution of experimental arthritis. J Immunol 151: 4344
-
(1993)
J Immunol
, vol.151
, pp. 4344
-
-
Allen, J.B.1
Wong, H.L.2
Costa, G.L.3
Bienkowski, M.J.4
Wahl, S.M.5
-
3
-
-
0025720735
-
The role of Jun. Fos and AP-1 complex in cell-proliferation and transformation
-
Angel P, Karin M (1991) The role of Jun. Fos and AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta 1072:129
-
(1991)
Biochim Biophys Acta
, vol.1072
, pp. 129
-
-
Angel, P.1
Karin, M.2
-
4
-
-
0027501020
-
Interleukin-1 receptor antagonist
-
Arend WP ( 1993) Interleukin-1 receptor antagonist. Adv Immunol 54:167
-
(1993)
Adv Immunol
, vol.54
, pp. 167
-
-
Arend, W.P.1
-
5
-
-
0028861236
-
Inhibition of the production and effects of interleukin-1 and tumor necrosis factor α in rheumatoid arthritis
-
Arend WP, Payer J-M (1995) Inhibition of the production and effects of interleukin-1 and tumor necrosis factor α in rheumatoid arthritis. Arthritis Rheum 38: 151
-
(1995)
Arthritis Rheum
, vol.38
, pp. 151
-
-
Arend, W.P.1
Payer, J.-M.2
-
6
-
-
0025288396
-
Biological properties of recombinant monocyte-derived interleukin I receptor antagonist
-
Arend WP, Welgus HG, Thompson RC, Eisenberg SP (1990) Biological properties of recombinant monocyte-derived interleukin I receptor antagonist. J Clin Invest 85:1694
-
(1990)
J Clin Invest
, vol.85
, pp. 1694
-
-
Arend, W.P.1
Welgus, H.G.2
Thompson, R.C.3
Eisenberg, S.P.4
-
7
-
-
0028172557
-
Binding of IL-1α, IL-1β, and IL-1 receptor anlagonisl by soluble IL-1 receptors and levels of soluble IL-1 receptors in synovial fluids
-
Arend WP, Malyak M, Smith MF Jr, Whisenand TD, Slack JL, Sims JE, Giri JG, Dower SK (1994) Binding of IL-1α, IL-1β, and IL-1 receptor anlagonisl by soluble IL-1 receptors and levels of soluble IL-1 receptors in synovial fluids. J Immunol 153:4766
-
(1994)
J Immunol
, vol.153
, pp. 4766
-
-
Arend, W.P.1
Malyak, M.2
Smith Jr., M.F.3
Whisenand, T.D.4
Slack, J.L.5
Sims, J.E.6
Giri, J.G.7
Dower, S.K.8
-
8
-
-
0029064447
-
Interleukin-1 receptor antagonist inhibits proteoglycan breakdown in antigen induced but not in polycation induced arthritis in the rabbit
-
Arner EC, Harris RR, DiMeo TM, Collins RC, Galbraith W (1995) Interleukin-1 receptor antagonist inhibits proteoglycan breakdown in antigen induced but not in polycation induced arthritis in the rabbit. J Rheumatol 22: 1338
-
(1995)
J Rheumatol
, vol.22
, pp. 1338
-
-
Arner, E.C.1
Harris, R.R.2
DiMeo, T.M.3
Collins, R.C.4
Galbraith, W.5
-
9
-
-
0028867899
-
Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
-
Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M (1995) Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis. Science 270:286
-
(1995)
Science
, vol.270
, pp. 286
-
-
Auphan, N.1
DiDonato, J.A.2
Rosette, C.3
Helmberg, A.4
Karin, M.5
-
10
-
-
0030747128
-
NF-κB as a frequent target for immunosuppressive and anti-inflammatory molecules
-
Baeuerle PA, Baichwal VR (1997) NF-κB as a frequent target for immunosuppressive and anti-inflammatory molecules. Adv Immunol 65:111
-
(1997)
Adv Immunol
, vol.65
, pp. 111
-
-
Baeuerle, P.A.1
Baichwal, V.R.2
-
11
-
-
0030973263
-
Prevention of murine collagen-induced arthritis in the knee and ipsilateral paw by local expression of human interleukin-1 receptor antagonist protein in the knee
-
Bakker AC, Joosten LAB, Arntz OJ, Helsen MMA, Bendele AM, Loo FAJ van de, Berg WB van den (1997) Prevention of murine collagen-induced arthritis in the knee and ipsilateral paw by local expression of human interleukin-1 receptor antagonist protein in the knee. Arthritis Rheum 40:893
-
Arthritis Rheum
, vol.40
, pp. 893
-
-
Bakker, A.C.1
Joosten, L.A.B.2
Arntz, O.J.3
Helsen, M.M.A.4
Bendele, A.M.5
Van De Loo, F.A.J.6
Van Den Berg, W.B.7
-
12
-
-
0027435633
-
Intraarticular expression of biologically active interleukin 1 receptor antagonist protein by ex vivo gene transfer
-
Bandara G, Mueller GM, Galea-Lauri J, Tindal MH, Georgescu HI, Suchanek MK, Hung GL, Glorioso JC, Robbins PD, Evans CH (1993 ) Intraarticular expression of biologically active interleukin 1 receptor antagonist protein by ex vivo gene transfer. Proc Natl Acad Sci USA 90:10764
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 10764
-
-
Bandara, G.1
Mueller, G.M.2
Galea-Lauri, J.3
Tindal, M.H.4
Georgescu, H.I.5
Suchanek, M.K.6
Hung, G.L.7
Glorioso, J.C.8
Robbins, P.D.9
Evans, C.H.10
-
13
-
-
0028799826
-
Transplantation of transduced chondrocytes protects articular cartilage from interleukin-1-induced extracellular matrix degradation
-
Baragi VM, Renkiewiez RR, Jordan H, Bonadio J, Hartman JW, Roessler BJ (1995) Transplantation of transduced chondrocytes protects articular cartilage from interleukin-1-induced extracellular matrix degradation. J Clin Invest 96:2454
-
(1995)
J Clin Invest
, vol.96
, pp. 2454
-
-
Baragi, V.M.1
Renkiewiez, R.R.2
Jordan, H.3
Bonadio, J.4
Hartman, J.W.5
Roessler, B.J.6
-
14
-
-
7844227231
-
Effects of interleukin-1 receptor antagonist alone and in combination with methotrexate in adjuvant arthritic rats
-
Bendele AM, Sennello G, McAbee T, Frazier J, Chlipala E (1997) Effects of interleukin-1 receptor antagonist alone and in combination with methotrexate in adjuvant arthritic rats. Arthritis Rheum 40:S181
-
(1997)
Arthritis Rheum
, vol.40
-
-
Bendele, A.M.1
Sennello, G.2
McAbee, T.3
Frazier, J.4
Chlipala, E.5
-
15
-
-
0029797868
-
Attenuation of collagen-induced arthritis in mice by treatment with vector cells engineered to secrete interleukin-13
-
Bessis N, Boissier MC, Ferrara P, Blankenstein T, Fradelizi D (1996) Attenuation of collagen-induced arthritis in mice by treatment with vector cells engineered to secrete interleukin-13. Eur J Immunol 26:2399
-
(1996)
Eur J Immunol
, vol.26
, pp. 2399
-
-
Bessis, N.1
Boissier, M.C.2
Ferrara, P.3
Blankenstein, T.4
Fradelizi, D.5
-
16
-
-
0028850009
-
Prolonged systemic-expression of human IL-1 receptor antagonist (hIL-1ra) in mice reconstituted with hematopoietic cells transduced with a retrovirus carrying the h1L-1ra cDNA
-
Boggs SS, Patrene KD, Mueller GM, Evans CH, Doughty LA, Robbins PD (1995) Prolonged systemic-expression of human IL-1 receptor antagonist (hIL-1ra) in mice reconstituted with hematopoietic cells transduced with a retrovirus carrying the h1L-1ra cDNA. Gene Therapy 2:632
-
(1995)
Gene Therapy
, vol.2
, pp. 632
-
-
Boggs, S.S.1
Patrene, K.D.2
Mueller, G.M.3
Evans, C.H.4
Doughty, L.A.5
Robbins, P.D.6
-
17
-
-
17444394445
-
Treatment of rheumatoid arthritis with recombinant human inlerleukin-1 receptor antagonist
-
in press
-
Bresnihan B, Alvaro-Gracia JM, Cobby M, Doherty M, Domljan Z, Emery P, Nuki G, Pavelka K, Rau R, Rozman B, Watt I, Williams B, Aitchison R, McCabe D, Musikic P (1998) Treatment of rheumatoid arthritis with recombinant human inlerleukin-1 receptor antagonist. Arthritis Rheum (in press)
-
(1998)
Arthritis Rheum
-
-
Bresnihan, B.1
Alvaro-Gracia, J.M.2
Cobby, M.3
Doherty, M.4
Domljan, Z.5
Emery, P.6
Nuki, G.7
Pavelka, K.8
Rau, R.9
Rozman, B.10
Watt, I.11
Williams, B.12
Aitchison, R.13
McCabe, D.14
Musikic, P.15
-
18
-
-
0030295177
-
The combination of endotoxin and dexamethasone induces type II interleukin I receptor (IL-1r II) in monocytes: A comparison Io inlerleukin 1β (IL-1β) and interleukin 1 receptor antagonist (IL-1ra)
-
Brown EA, Dare HA, Marsh CB, Wewers MD (1996) The combination of endotoxin and dexamethasone induces type II interleukin I receptor (IL-1r II) in monocytes: a comparison Io inlerleukin 1β (IL-1β) and interleukin 1 receptor antagonist (IL-1ra). Cytokine 8:828
-
(1996)
Cytokine
, vol.8
, pp. 828
-
-
Brown, E.A.1
Dare, H.A.2
Marsh, C.B.3
Wewers, M.D.4
-
19
-
-
0029145145
-
The inhibitory activity of human interleukin-1 reeeplor antagonist is enhanced by type II interleukin-1 soluble receptor and hindered by type I interleukin-1 soluble receptor
-
Burger D, Chicheportiche R, Giri JG, Dayer J-M (1995) The inhibitory activity of human interleukin-1 reeeplor antagonist is enhanced by type II interleukin-1 soluble receptor and hindered by type I interleukin-1 soluble receptor. J Clin Invest 96:38
-
(1995)
J Clin Invest
, vol.96
, pp. 38
-
-
Burger, D.1
Chicheportiche, R.2
Giri, J.G.3
Dayer, J.-M.4
-
20
-
-
0029943271
-
Dose-range and dose-frequency study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis
-
Campion GV, Lebsack ME, Lookabaugh J, Gordon G, Catalano MA (1996) Dose-range and dose-frequency study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis. Arthritis Rheum 39:1092
-
(1996)
Arthritis Rheum
, vol.39
, pp. 1092
-
-
Campion, G.V.1
Lebsack, M.E.2
Lookabaugh, J.3
Gordon, G.4
Catalano, M.A.5
-
21
-
-
0029814957
-
Chondroproteetive effect of intraarticular injections of interleukin-1 receptor antagonist in experimental osteoarthritis. Suppression of collagenase-1 expression
-
Caron JP, Fernandes JC, Martel-Pelletier J, tardif G, Mineau F, Geng C, Pelletier J-P (1996) Chondroproteetive effect of intraarticular injections of interleukin-1 receptor antagonist in experimental osteoarthritis. Suppression of collagenase-1 expression. Arthritis Rheum 39:1535
-
(1996)
Arthritis Rheum
, vol.39
, pp. 1535
-
-
Caron, J.P.1
Fernandes, J.C.2
Martel-Pelletier, J.3
Tardif, G.4
Mineau, F.5
Geng, C.6
Pelletier, J.-P.7
-
22
-
-
0029070119
-
A randomized, controlled trial of interleukin-10 in humans: Inhibition of inflammatory cytokine production and immune responses
-
Chernoff AE, Granowitz EV, Shapiro L, Vannier E, Lonnemann G, Angel JB, Kennedy JS, Rabson AR, Wolff SM, Dinarello CA (1995) A randomized, controlled trial of interleukin-10 in humans: inhibition of inflammatory cytokine production and immune responses. J Immunol 154:5492
-
(1995)
J Immunol
, vol.154
, pp. 5492
-
-
Chernoff, A.E.1
Granowitz, E.V.2
Shapiro, L.3
Vannier, E.4
Lonnemann, G.5
Angel, J.B.6
Kennedy, J.S.7
Rabson, A.R.8
Wolff, S.M.9
Dinarello, C.A.10
-
23
-
-
0028943335
-
Dysregulation of the in vivo production of interleukin-1 receptor antagonist in patients with rheumatoid arthritis
-
Chikanza IC, Roux-Lombard P, Dayer J-M, Panayi G (1995) Dysregulation of the in vivo production of interleukin-1 receptor antagonist in patients with rheumatoid arthritis. Arthritis Rheum 38:642
-
(1995)
Arthritis Rheum
, vol.38
, pp. 642
-
-
Chikanza, I.C.1
Roux-Lombard, P.2
Dayer, J.-M.3
Panayi, G.4
-
24
-
-
4243881257
-
A slow release formulation of interleukin-1 receptor antagonist (IL-1Ra) exhibits improved in vivo activity
-
Collins D, McAbee T, Woodward M, Frazier J, Chlipala E, Bendele A (1997) A slow release formulation of interleukin-1 receptor antagonist (IL-1Ra) exhibits improved in vivo activity. Arthritis Rheum 40: S180
-
(1997)
Arthritis Rheum
, vol.40
-
-
Collins, D.1
McAbee, T.2
Woodward, M.3
Frazier, J.4
Chlipala, E.5
Bendele, A.6
-
25
-
-
0028004236
-
The type II "decoy" receptor: A novel regulatory pathway for interleukin 1
-
Colotta F, Dower SK, Sims JE, Mantovani A (1994) The type II "decoy" receptor: a novel regulatory pathway for interleukin 1. Immunol Today 15:562
-
(1994)
Immunol Today
, vol.15
, pp. 562
-
-
Colotta, F.1
Dower, S.K.2
Sims, J.E.3
Mantovani, A.4
-
26
-
-
4243609362
-
Selective proteasome inhibition attenuates experimental polyarthritis via inhibition of nuclear transcription factor κB (NFκB) activation
-
Conner EM, Fuseler JW, Davis JM, Laroux FS, Palombella VJ, Brand S, Wolf RE, Grisham MB (1997) Selective proteasome inhibition attenuates experimental polyarthritis via inhibition of nuclear transcription factor κB (NFκB) activation. Arthritis Rheum 40:S322
-
(1997)
Arthritis Rheum
, vol.40
-
-
Conner, E.M.1
Fuseler, J.W.2
Davis, J.M.3
Laroux, F.S.4
Palombella, V.J.5
Brand, S.6
Wolf, R.E.7
Grisham, M.B.8
-
27
-
-
0027492915
-
Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFNγ or IL-10
-
De Waal Malefyt R, Figdor CG, Huijbens R, Mohan-Peterson S, Benett B, Culpepper J, Dang W, Zurawski G, De Vries JE (1993) Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFNγ or IL-10. J Immunol 151: 6370
-
(1993)
J Immunol
, vol.151
, pp. 6370
-
-
De Waal Malefyt, R.1
Figdor, C.G.2
Huijbens, R.3
Mohan-Peterson, S.4
Benett, B.5
Culpepper, J.6
Dang, W.7
Zurawski, G.8
De Vries, J.E.9
-
28
-
-
0026545719
-
Localization of interleukin-1 alpha, type 1 interleukin-1 receptor and interleukin-1 receptor antagonist in the synovial membrane and cartilage/pannus junction in rheumatoid arthritis
-
Deleuran BW, Chu CQ, Field M, Brennan FM, Katsikis P, Feldmann M, Maini RN (1992) Localization of interleukin-1 alpha, type 1 interleukin-1 receptor and interleukin-1 receptor antagonist in the synovial membrane and cartilage/pannus junction in rheumatoid arthritis. Br J Rheumatol 31:801
-
(1992)
Br J Rheumatol
, vol.31
, pp. 801
-
-
Deleuran, B.W.1
Chu, C.Q.2
Field, M.3
Brennan, F.M.4
Katsikis, P.5
Feldmann, M.6
Maini, R.N.7
-
29
-
-
0029979369
-
Biologic basis for interleukin-1 in disease
-
Dinarello CA (1996) Biologic basis for interleukin-1 in disease. Blood 87:2095
-
(1996)
Blood
, vol.87
, pp. 2095
-
-
Dinarello, C.A.1
-
30
-
-
0027384651
-
Tissue-specific regulation of IL-6 production by IL-4. Differential effects of IL-4 on nuclear factor-κB activity in monocytes and fibroblasts
-
Donnelly RP, Crofford LJ, Freeman SL, Buras J, Remmers E, Wilder RL, Fenton MJ (1993) Tissue-specific regulation of IL-6 production by IL-4. Differential effects of IL-4 on nuclear factor-κB activity in monocytes and fibroblasts. J Immunol 151:5603
-
(1993)
J Immunol
, vol.151
, pp. 5603
-
-
Donnelly, R.P.1
Crofford, L.J.2
Freeman, S.L.3
Buras, J.4
Remmers, E.5
Wilder, R.L.6
Fenton, M.J.7
-
31
-
-
0028177119
-
Interleukin-1 antagonists
-
Dower SK, Fanslow W, Jacobs C, Waugh S, Sims JE, Widmer MB (1994) Interleukin-1 antagonists. Ther Immunol 1:113
-
(1994)
Ther Immunol
, vol.1
, pp. 113
-
-
Dower, S.K.1
Fanslow, W.2
Jacobs, C.3
Waugh, S.4
Sims, J.E.5
Widmer, M.B.6
-
32
-
-
0030039524
-
Recombinant human interleukin-1 receptor type I in the treatment of patients with active rheumatoid arthritis
-
Drevlow BE, Lovis R, Haag MA, Sinacore JM, Jacobs C, Blosche C, Landay A, Moreland LW, Pope RM (1996) Recombinant human interleukin-1 receptor type I in the treatment of patients with active rheumatoid arthritis. Arthritis Rheum 39:257
-
(1996)
Arthritis Rheum
, vol.39
, pp. 257
-
-
Drevlow, B.E.1
Lovis, R.2
Haag, M.A.3
Sinacore, J.M.4
Jacobs, C.5
Blosche, C.6
Landay, A.7
Moreland, L.W.8
Pope, R.M.9
-
33
-
-
0025954704
-
Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: Evolution of a cytokine control mechanism
-
Eisenberg SP, Brewer MT, Verderber E, Heimdal P, Brandhuber BJ, Thompson RC (1991) Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanism. Proc Natl Acad Sci USA 88:5232
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 5232
-
-
Eisenberg, S.P.1
Brewer, M.T.2
Verderber, E.3
Heimdal, P.4
Brandhuber, B.J.5
Thompson, R.C.6
-
34
-
-
0031568401
-
Response to local inflammation of IL-1 beta-converting enzyme-deficient mice
-
Fantuzzi G, Ku G, Harding MW, Livingston DJ, Sipe JD, Kuida K, Flavell RA, Dinarello CA (1997) Response to local inflammation of IL-1 beta-converting enzyme-deficient mice. J Immunol 158:1818
-
(1997)
J Immunol
, vol.158
, pp. 1818
-
-
Fantuzzi, G.1
Ku, G.2
Harding, M.W.3
Livingston, D.J.4
Sipe, J.D.5
Kuida, K.6
Flavell, R.A.7
Dinarello, C.A.8
-
35
-
-
0026721695
-
IL-1 receptor antagonist protein production and gene expression in rheumatoid arthritis and osteoarthritis synovium
-
Firestein GS, Berger AE, Tracey DE, Chosay JG, Chapman DL, Paine MM, Yu C, Zvaifler NJ (1992) IL-1 receptor antagonist protein production and gene expression in rheumatoid arthritis and osteoarthritis synovium. J Immunol 149:1054
-
(1992)
J Immunol
, vol.149
, pp. 1054
-
-
Firestein, G.S.1
Berger, A.E.2
Tracey, D.E.3
Chosay, J.G.4
Chapman, D.L.5
Paine, M.M.6
Yu, C.7
Zvaifler, N.J.8
-
36
-
-
0028295883
-
Synovial interleukin-1 receptor antagonist and interleukin-1 balance in rheumatoid arthritis
-
Firestein GS, Boyle DL, Yu C, Paine MM, Whisenand TD, Zvaifler NJ, Arend WP (1994) Synovial interleukin-1 receptor antagonist and interleukin-1 balance in rheumatoid arthritis. Arthritis Rheum 37: 644
-
(1994)
Arthritis Rheum
, vol.37
, pp. 644
-
-
Firestein, G.S.1
Boyle, D.L.2
Yu, C.3
Paine, M.M.4
Whisenand, T.D.5
Zvaifler, N.J.6
Arend, W.P.7
-
37
-
-
0029795485
-
Administration of neutralizing antibody against rabbit IL-1 receptor antagonist exacerbates lipopolysaccharide-induced arthritis in rabbits
-
Fukumoto T, Matsukawa A, Ohkawara S, Takagi K, Yoshinaga M (1996) Administration of neutralizing antibody against rabbit IL-1 receptor antagonist exacerbates lipopolysaccharide-induced arthritis in rabbits. Inflamm Res 45:479
-
(1996)
Inflamm Res
, vol.45
, pp. 479
-
-
Fukumoto, T.1
Matsukawa, A.2
Ohkawara, S.3
Takagi, K.4
Yoshinaga, M.5
-
39
-
-
0000325444
-
Gene therapy for arthritis - Treatment of the first three patients
-
Ghivizzani SC, Kang R, Muzzonigro T, Whalen J, Walkins SC, Herndon JH, Robbins PD, Evans CH (1997) Gene therapy for arthritis - treatment of the first three patients. Arthritis Rheum 40:S223
-
(1997)
Arthritis Rheum
, vol.40
-
-
Ghivizzani, S.C.1
Kang, R.2
Muzzonigro, T.3
Whalen, J.4
Walkins, S.C.5
Herndon, J.H.6
Robbins, P.D.7
Evans, C.H.8
-
40
-
-
0029563524
-
Nuclear factor-κB in rheumatoid synovium. Localization of p50 and p65
-
Handel ML, McMorrow LB, Gravallese EM (1995) Nuclear factor-κB in rheumatoid synovium. Localization of p50 and p65. Arthritis Rheum 38:1762
-
(1995)
Arthritis Rheum
, vol.38
, pp. 1762
-
-
Handel, M.L.1
McMorrow, L.B.2
Gravallese, E.M.3
-
41
-
-
0029916803
-
The superficial layer of human articular cartilage is more susceptible to interleukin-1-induced damage than the deeper layers
-
Hauselmann HJ, Flechtenmacher J, Michal L, Thonar EJ-MA, Shinmei M, Kuettner KE, Aydelotte MB (1996) The superficial layer of human articular cartilage is more susceptible to interleukin-1-induced damage than the deeper layers. Arthritis Rheum 39:478
-
(1996)
Arthritis Rheum
, vol.39
, pp. 478
-
-
Hauselmann, H.J.1
Flechtenmacher, J.2
Michal, L.3
Thonar, E.J.-M.A.4
Shinmei, M.5
Kuettner, K.E.6
Aydelotte, M.B.7
-
42
-
-
0026162985
-
Inhibition of interleukin-1-induced synovitis and articular cartilage proteoglycan loss in the rabbit knee by recombinant interleukin-1 receptor antagonist
-
Henderson B, Thompson RC, Hardingham T, Lewthwaite J (1991) Inhibition of interleukin-1-induced synovitis and articular cartilage proteoglycan loss in the rabbit knee by recombinant interleukin-1 receptor antagonist. Cytokine 3:246
-
(1991)
Cytokine
, vol.3
, pp. 246
-
-
Henderson, B.1
Thompson, R.C.2
Hardingham, T.3
Lewthwaite, J.4
-
43
-
-
0029768091
-
Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice
-
Hirsch E, Irikura VM, Paul SM, Hirsh D (1996) Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice. Proc Natl Acad Sci USA 93:11008
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11008
-
-
Hirsch, E.1
Irikura, V.M.2
Paul, S.M.3
Hirsh, D.4
-
44
-
-
0031059255
-
Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis
-
Joosten LAB, Lubberts E, Durez P, Helsen MMA, Jacobs MJM, Goldman M, Berg WB van den (1997) Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Arthritis Rheum 40:249
-
(1997)
Arthritis Rheum
, vol.40
, pp. 249
-
-
Joosten, L.A.B.1
Lubberts, E.2
Durez, P.3
Helsen, M.M.A.4
Jacobs, M.J.M.5
Goldman, M.6
Van Den Berg, W.B.7
-
45
-
-
0029168043
-
Effects of high-dose fish oil on rheumatoid arthritis after stopping nonsteroidal antiinflammatory drugs
-
Kremer JM, Lawrence DA, Petrillo GF, Litts LL, Mullaly PM, Rynes RI, stocker RP, Parhami N, Greenstein NS, Fuchs BR, Mathur A, Robinson DR, Sperling RI, Bigaouette J (1995) Effects of high-dose fish oil on rheumatoid arthritis after stopping nonsteroidal antiinflammatory drugs. Arthritis Rheum 38:1107
-
(1995)
Arthritis Rheum
, vol.38
, pp. 1107
-
-
Kremer, J.M.1
Lawrence, D.A.2
Petrillo, G.F.3
Litts, L.L.4
Mullaly, P.M.5
Rynes, R.I.6
Stocker, R.P.7
Parhami, N.8
Greenstein, N.S.9
Fuchs, B.R.10
Mathur, A.11
Robinson, D.R.12
Sperling, R.I.13
Bigaouette, J.14
-
46
-
-
0029971948
-
Interleukin-1β converting enzyme inhibition blocks progression of type II collagen-induced arthritis in mice
-
Ku G, Faust T, Lauffer LL, Livingston DJ, Harding MW (1996) Interleukin-1β converting enzyme inhibition blocks progression of type II collagen-induced arthritis in mice. Cytokine 8:377
-
(1996)
Cytokine
, vol.8
, pp. 377
-
-
Ku, G.1
Faust, T.2
Lauffer, L.L.3
Livingston, D.J.4
Harding, M.W.5
-
47
-
-
0028246840
-
Constitutive c-fos expression in osteoblastic MC3T3-E1 cells stimulates osteoclast maturation and osteoclastic bone resorption
-
Kuroki Y, Shiozawa S, Sugimoto T, Kanatani M, Kaji H, Miyauchi A, Chihara K (1994) Constitutive c-fos expression in osteoblastic MC3T3-E1 cells stimulates osteoclast maturation and osteoclastic bone resorption. Clin Exp Immunol 95:536
-
(1994)
Clin Exp Immunol
, vol.95
, pp. 536
-
-
Kuroki, Y.1
Shiozawa, S.2
Sugimoto, T.3
Kanatani, M.4
Kaji, H.5
Miyauchi, A.6
Chihara, K.7
-
48
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kühn R, Löhler J, Rennick D, Rajewsky K, Müller W (1993) Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75:263
-
(1993)
Cell
, vol.75
, pp. 263
-
-
Kühn, R.1
Löhler, J.2
Rennick, D.3
Rajewsky, K.4
Müller, W.5
-
49
-
-
0028855894
-
IL-10 inhibits metalloproteinase and stimulates TIMP-I production in human mononuclear phagocytes
-
Lacraz S, Nicod LP, Chicheportiche R, Welgus HG, Dayer J-M (1995) IL-10 inhibits metalloproteinase and stimulates TIMP-I production in human mononuclear phagocytes. J Clin Invest 96:2304
-
(1995)
J Clin Invest
, vol.96
, pp. 2304
-
-
Lacraz, S.1
Nicod, L.P.2
Chicheportiche, R.3
Welgus, H.G.4
Dayer, J.-M.5
-
50
-
-
0030781140
-
In vivo suppression of NF-κB and preservation of IκBα by interleukin-10 and interleukin-13
-
Lentsch AB, Shanley TP, Sarma V, Ward PA (1997) In vivo suppression of NF-κB and preservation of IκBα by interleukin-10 and interleukin-13. J Clin Invest 100:2443
-
(1997)
J Clin Invest
, vol.100
, pp. 2443
-
-
Lentsch, A.B.1
Shanley, T.P.2
Sarma, V.3
Ward, P.A.4
-
51
-
-
0028205283
-
The effect of recombinant human interleukin-1 receptor antagonist on the induction phase of antigen induced arthritis in the rabbit
-
Lewthwaite J, Blake SM, Hardingham TE, Warden PJ, Henderson B (1994) The effect of recombinant human interleukin-1 receptor antagonist on the induction phase of antigen induced arthritis in the rabbit. J Rheumatol 21:467
-
(1994)
J Rheumatol
, vol.21
, pp. 467
-
-
Lewthwaite, J.1
Blake, S.M.2
Hardingham, T.E.3
Warden, P.J.4
Henderson, B.5
-
52
-
-
0028984948
-
Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock
-
Li P, Allen H, Banerjee S, Franklin L, Herzog L, Johnston C, McDowell J, Paskind M, Rodman L, Salfeld J, Towne F, Tracey D, Warwell S, Wei F-Y, Wong W, Kamen R, Seshadri T (1995) Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock. Cell 80:401
-
(1995)
Cell
, vol.80
, pp. 401
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Franklin, L.4
Herzog, L.5
Johnston, C.6
McDowell, J.7
Paskind, M.8
Rodman, L.9
Salfeld, J.10
Towne, F.11
Tracey, D.12
Warwell, S.13
Wei, F.-Y.14
Wong, W.15
Kamen, R.16
Seshadri, T.17
-
53
-
-
0030071084
-
Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA
-
Makarov SS, Olsen JC, Johnston WN, Anderle SK, Brown RR, Baldwin AS, Haskill JS, Schwab JH (1996) Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA. Proc Natl Acad Sci USA 93:402
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 402
-
-
Makarov, S.S.1
Olsen, J.C.2
Johnston, W.N.3
Anderle, S.K.4
Brown, R.R.5
Baldwin, A.S.6
Haskill, J.S.7
Schwab, J.H.8
-
54
-
-
0030442286
-
High dose intravenous immunoglobulin (IVIg) in severe refractory rheumatoid arthritis: No evidence for efficacy
-
Maksymowych WP, avina-Zubieta A, Luong M, Russel AS (1996) High dose intravenous immunoglobulin (IVIg) in severe refractory rheumatoid arthritis: no evidence for efficacy. Clin Exp Rheum 14:657
-
(1996)
Clin Exp Rheum
, vol.14
, pp. 657
-
-
Maksymowych, W.P.1
Avina-Zubieta, A.2
Luong, M.3
Russel, A.S.4
-
55
-
-
0027190338
-
Levels of synovial fluid interleukin-1 receptor antagonist in rheumatoid arthritis and other arthropathies. Potential contribution from synovial fluid neutrophils
-
Malyak M, Swaney RE, Arend WP (1993) Levels of synovial fluid interleukin-1 receptor antagonist in rheumatoid arthritis and other arthropathies. Potential contribution from synovial fluid neutrophils. Arthritis Rheum 36:781
-
(1993)
Arthritis Rheum
, vol.36
, pp. 781
-
-
Malyak, M.1
Swaney, R.E.2
Arend, W.P.3
-
56
-
-
0028218242
-
Peripheral blood neutrophil production of interleukin-1 receptor antagonist and interleukin-1β
-
Malyak M, Smith MFJr, Abel AA, Arend WP (1994) Peripheral blood neutrophil production of interleukin-1 receptor antagonist and interleukin-1β. J Clin Immunol 14:20
-
(1994)
J Clin Immunol
, vol.14
, pp. 20
-
-
Malyak, M.1
Smith Jr., M.F.2
Abel, A.A.3
Arend, W.P.4
-
57
-
-
0027165586
-
Production of IL-1 and IL-1 receptor antagonist and the pathological significance in lipopolysaccharide-induced arthritis in rabbits
-
Matsukawa A, Ohkawara S, Maeda T, Takagi K, Yoshinaga M (1993) Production of IL-1 and IL-1 receptor antagonist and the pathological significance in lipopolysaccharide-induced arthritis in rabbits. Clin Exp Immunol 93:206
-
(1993)
Clin Exp Immunol
, vol.93
, pp. 206
-
-
Matsukawa, A.1
Ohkawara, S.2
Maeda, T.3
Takagi, K.4
Yoshinaga, M.5
-
58
-
-
0027397839
-
Balance of synovial fluid IL-1β and IL-1 receptor antagonist and recovery from Lyme arthritis
-
Miller LC, Lynch EA, Isa S, Logan JW, Dinarello CA, Steere AC (1993) Balance of synovial fluid IL-1β and IL-1 receptor antagonist and recovery from Lyme arthritis. Lancet 341:146
-
(1993)
Lancet
, vol.341
, pp. 146
-
-
Miller, L.C.1
Lynch, E.A.2
Isa, S.3
Logan, J.W.4
Dinarello, C.A.5
Steere, A.C.6
-
59
-
-
0031112232
-
Human IL-1Ra gene transfer into human synovial fibroblasts is chondroprotective
-
Muller-Ladner U, Roberts CR, Franklin BN, Gay RE, Robbins PD, Evans CH, Gay S (1997) Human IL-1Ra gene transfer into human synovial fibroblasts is chondroprotective. J Immunol 158:3492
-
(1997)
J Immunol
, vol.158
, pp. 3492
-
-
Muller-Ladner, U.1
Roberts, C.R.2
Franklin, B.N.3
Gay, R.E.4
Robbins, P.D.5
Evans, C.H.6
Gay, S.7
-
60
-
-
0029836444
-
Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice
-
Neurath MF, Petterson S, Meyer zum Büschenfelde K-H, Stroher W (1996) Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice. Nat Med 2:998
-
(1996)
Nat Med
, vol.2
, pp. 998
-
-
Neurath, M.F.1
Petterson, S.2
Meyer Zum Büschenfelde, K.-H.3
Stroher, W.4
-
61
-
-
0000428989
-
Interleukin-1 receptor antagonist continues to demonstrate clinical improvement in rheumatoid arthritis
-
Nuki G, Rozman B, Pavelka K, Emery P, Lookabaugh J, Musikic P (1997) Interleukin-1 receptor antagonist continues to demonstrate clinical improvement in rheumatoid arthritis. Arthritis Rheum 40: S224
-
(1997)
Arthritis Rheum
, vol.40
-
-
Nuki, G.1
Rozman, B.2
Pavelka, K.3
Emery, P.4
Lookabaugh, J.5
Musikic, P.6
-
62
-
-
0029967052
-
Suppression of antigen-induced arthritis in rabbits by ex vivo gene therapy
-
Otani K, Nita I, Macaulay W, Georgescu HI, Robbins PD, Evans CH (1996) Suppression of antigen-induced arthritis in rabbits by ex vivo gene therapy. J Immunol 156:3558
-
(1996)
J Immunol
, vol.156
, pp. 3558
-
-
Otani, K.1
Nita, I.2
Macaulay, W.3
Georgescu, H.I.4
Robbins, P.D.5
Evans, C.H.6
-
63
-
-
0025866180
-
Transcriptional and posttranscriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-β1 in human fibroblasts
-
Overall CM, Wrana JL, Sodek J (1991) Transcriptional and posttranscriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-β1 in human fibroblasts. J Biol Chem 266:14064
-
(1991)
J Biol Chem
, vol.266
, pp. 14064
-
-
Overall, C.M.1
Wrana, J.L.2
Sodek, J.3
-
64
-
-
0000609002
-
Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint
-
Pettipher ER, Higgs GA, Henderson B (1986) Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint. Proc Natl Acad Sci USA 83:8749
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 8749
-
-
Pettipher, E.R.1
Higgs, G.A.2
Henderson, B.3
-
65
-
-
0026693768
-
Influence of hypercortisolemia on the acute-phase protein response to endotoxin in humans
-
Rock CS, Coyle SM, Keogh CV, Lazarus DD, Hawes AS, Leskiw M, Moldawer LL, Stein TP, Lowry SF (1992) Influence of hypercortisolemia on the acute-phase protein response to endotoxin in humans. Surgery 112:467
-
(1992)
Surgery
, vol.112
, pp. 467
-
-
Rock, C.S.1
Coyle, S.M.2
Keogh, C.V.3
Lazarus, D.D.4
Hawes, A.S.5
Leskiw, M.6
Moldawer, L.L.7
Stein, T.P.8
Lowry, S.F.9
-
66
-
-
0027296070
-
Adenoviral-mediated gene transfer to rabbit synovium in vivo
-
Roessler BJ, Allen ED, Wilson JM, Hartman JW, Davidson BL (1993) Adenoviral-mediated gene transfer to rabbit synovium in vivo. J Clin Invest 92:1085
-
(1993)
J Clin Invest
, vol.92
, pp. 1085
-
-
Roessler, B.J.1
Allen, E.D.2
Wilson, J.M.3
Hartman, J.W.4
Davidson, B.L.5
-
67
-
-
0029133070
-
Inhibition of interleukin-1-induced effects in synoviocytes transduced with the human IL-1 receptor antagonist cDNA using an adenoviral vector
-
Roessler BJ, Hartman JW, Vallance DK, Latta JM, Janish SL, Davidson BL (1995) Inhibition of interleukin-1-induced effects in synoviocytes transduced with the human IL-1 receptor antagonist cDNA using an adenoviral vector. Hum Gene Ther 6:307
-
(1995)
Hum Gene Ther
, vol.6
, pp. 307
-
-
Roessler, B.J.1
Hartman, J.W.2
Vallance, D.K.3
Latta, J.M.4
Janish, S.L.5
Davidson, B.L.6
-
68
-
-
0029658494
-
Manipulation of distinct NFκB proteins alters interleukin-1β-induced human rheumatoid synovial fibroblast prostaglandin E2 formation
-
Roshak AK, Jackson JR, McGough K, Chabot-Fletcher M, Mochan E, Marshall LA (1996) Manipulation of distinct NFκB proteins alters interleukin-1β-induced human rheumatoid synovial fibroblast prostaglandin E2 formation. J Biol Chem 271:31496
-
(1996)
J Biol Chem
, vol.271
, pp. 31496
-
-
Roshak, A.K.1
Jackson, J.R.2
McGough, K.3
Chabot-Fletcher, M.4
Mochan, E.5
Marshall, L.A.6
-
69
-
-
0027497856
-
Elaboration of interleukin 1-receptor antagonist is not attenuated by glucocorticoids after endotoxemia
-
Santos AA, Scheltinga MR, Lynch E, Brown EF, Lawton P, Chambers E, Browning J, Dinarello CA, Wolff SM, Wilmore DW (1993) Elaboration of interleukin 1-receptor antagonist is not attenuated by glucocorticoids after endotoxemia. Arch Surg 128:138
-
(1993)
Arch Surg
, vol.128
, pp. 138
-
-
Santos, A.A.1
Scheltinga, M.R.2
Lynch, E.3
Brown, E.F.4
Lawton, P.5
Chambers, E.6
Browning, J.7
Dinarello, C.A.8
Wolff, S.M.9
Wilmore, D.W.10
-
70
-
-
0028174623
-
Characterization of anti-IL-1α autoantibodies in the sera from healthy humans
-
Satoh H, Chizzonite R, Ostrowski C, Ni-Wu G, Kim H, Fayer B, Mae N, Nadeau R, Liberato DJ (1994) Characterization of anti-IL-1α autoantibodies in the sera from healthy humans. Immunopharmacology 27:107
-
(1994)
Immunopharmacology
, vol.27
, pp. 107
-
-
Satoh, H.1
Chizzonite, R.2
Ostrowski, C.3
Ni-Wu, G.4
Kim, H.5
Fayer, B.6
Mae, N.7
Nadeau, R.8
Liberato, D.J.9
-
71
-
-
0028879819
-
Role of transcriptional activation of IκBa in mediation of immunosuppression by glucocorticoids
-
Scheimnan RI, Cogswell PC, Lofquist aK, Baldwin AS (1995) Role of transcriptional activation of IκBa in mediation of immunosuppression by glucocorticoids. Science 270:283
-
(1995)
Science
, vol.270
, pp. 283
-
-
Scheimnan, R.I.1
Cogswell, P.C.2
Lofquist, A.K.3
Baldwin, A.S.4
-
72
-
-
0025789642
-
Pro- and anti-inflammatory roles of interleukin-1 in recurrence of bacterial cell wall-induced arthritis in rats
-
Schwab JH, Anderle SK, Brown RR, Dalldorf FG, Thompson RC (1991) Pro- and anti-inflammatory roles of interleukin-1 in recurrence of bacterial cell wall-induced arthritis in rats. Infect Immun 59:4436
-
(1991)
Infect Immun
, vol.59
, pp. 4436
-
-
Schwab, J.H.1
Anderle, S.K.2
Brown, R.R.3
Dalldorf, F.G.4
Thompson, R.C.5
-
73
-
-
0025295723
-
An interleukin-1 inhibitor affects both cell-associated interleukin-1-induced T cell proliferation and PGE2/collagenase production by human dermal fibroblasts and synovial cells
-
Seckinger P, Kaufmann M-T, Dayer J-M (1990) An interleukin-1 inhibitor affects both cell-associated interleukin-1-induced T cell proliferation and PGE2/collagenase production by human dermal fibroblasts and synovial cells. Immunobiology 180:316
-
(1990)
Immunobiology
, vol.180
, pp. 316
-
-
Seckinger, P.1
Kaufmann, M.-T.2
Dayer, J.-M.3
-
74
-
-
0025614619
-
Natural and recombinant human IL-1 receptor antagonists block the effects of IL-1 on bone resorption and prostaglandin production
-
Seckinger P, Klein-Nulend J, Alander C, Thompson RC, Dayer J-M, Raisz LG (1990) Natural and recombinant human IL-1 receptor antagonists block the effects of IL-1 on bone resorption and prostaglandin production. J Immunol 145:4181
-
(1990)
J Immunol
, vol.145
, pp. 4181
-
-
Seckinger, P.1
Klein-Nulend, J.2
Alander, C.3
Thompson, R.C.4
Dayer, J.-M.5
Raisz, L.G.6
-
75
-
-
0025668548
-
Modulation of the effects of interleukin-1 on glycosaminoglycan synthesis by the urine-derived interleukin-1 inhibitor, but not by interleukin-6
-
Seckinger P, Yaron I, Meyer FA, Yaron M, Dayer J-M (1990) Modulation of the effects of interleukin-1 on glycosaminoglycan synthesis by the urine-derived interleukin-1 inhibitor, but not by interleukin-6. Arthritis Rheum 33:1807
-
(1990)
Arthritis Rheum
, vol.33
, pp. 1807
-
-
Seckinger, P.1
Yaron, I.2
Meyer, F.A.3
Yaron, M.4
Dayer, J.-M.5
-
76
-
-
0029740907
-
Interleukin 1 (IL-1) receptor antagonist, soluble tumor necrosis factor receptors. IL-1β, and IL-8: Markers of remission in rheumatoid arthritis during treatment with methotrexate
-
Seitz M, Loetcher P, Dewald B, Towbin H, Rordorf C, Gallati H, Gerber NJ (1996) Interleukin 1 (IL-1) receptor antagonist, soluble tumor necrosis factor receptors. IL-1β, and IL-8: markers of remission in rheumatoid arthritis during treatment with methotrexate. J Rheumatol 23:1512
-
(1996)
J Rheumatol
, vol.23
, pp. 1512
-
-
Seitz, M.1
Loetcher, P.2
Dewald, B.3
Towbin, H.4
Rordorf, C.5
Gallati, H.6
Gerber, N.J.7
-
77
-
-
0028908909
-
Increased IL-1 receptor antagonist (IL-1ra) production and decreased IL-1β/IL-1ra ratio in mononuclear cells from rheumatoid arthritis patients
-
Shingu M, Fujikawa Y, Wada T, Nonaka S, Nobunaga M (1995) Increased IL-1 receptor antagonist (IL-1ra) production and decreased IL-1β/IL-1ra ratio in mononuclear cells from rheumatoid arthritis patients. Br J Rheumatol 34:24
-
(1995)
Br J Rheumatol
, vol.34
, pp. 24
-
-
Shingu, M.1
Fujikawa, Y.2
Wada, T.3
Nonaka, S.4
Nobunaga, M.5
-
78
-
-
0026545590
-
Destructive arthritis without lymphocyte infiltration in H2-c-fos transgenic mice
-
Shiozawa S, Shiozawa K, Fujita T, Tokuhisa T (1992) Destructive arthritis without lymphocyte infiltration in H2-c-fos transgenic mice. J Immunol 148:3100
-
(1992)
J Immunol
, vol.148
, pp. 3100
-
-
Shiozawa, S.1
Shiozawa, K.2
Fujita, T.3
Tokuhisa, T.4
-
79
-
-
0030971406
-
Studies on the contribution of c-fos/AP-1 to arthritic joint destruction
-
Shiozawa S, Shimizu K, Tanaka K, Hino K (1997) Studies on the contribution of c-fos/AP-1 to arthritic joint destruction. J Clin Invest 99: 1210
-
(1997)
J Clin Invest
, vol.99
, pp. 1210
-
-
Shiozawa, S.1
Shimizu, K.2
Tanaka, K.3
Hino, K.4
-
80
-
-
0026025748
-
Biologic effects of an interleukin-1 receptor antagonist protein on interleukin-1-stimulated cartilage erosion and chondrocyte responsiveness
-
Smith RJ, Chin JE, Sam LM, Justen JM (1991) Biologic effects of an interleukin-1 receptor antagonist protein on interleukin-1-stimulated cartilage erosion and chondrocyte responsiveness. Arthritis Rheum 34:78
-
(1991)
Arthritis Rheum
, vol.34
, pp. 78
-
-
Smith, R.J.1
Chin, J.E.2
Sam, L.M.3
Justen, J.M.4
-
81
-
-
0023926859
-
Exacerbation of arthritis by IL-1 in rat joints previously injured by peptidoglycan-polysaccharide
-
Stimpson SA, Dalldorf FG, Otterness IG, Schwab JH (1988) Exacerbation of arthritis by IL-1 in rat joints previously injured by peptidoglycan-polysaccharide. J Immunol 140:2964
-
(1988)
J Immunol
, vol.140
, pp. 2964
-
-
Stimpson, S.A.1
Dalldorf, F.G.2
Otterness, I.G.3
Schwab, J.H.4
-
82
-
-
0029951421
-
Interleukin-4 inhibits prostaglandin E2 production by freshly prepared adherent rheumatoid synovial cells via inhibition of biosynthesis and gene expression of cyclo-oxygenase II but not of cyclo-oxygenase I
-
Sugiyama E, Taki H, Kuroda A, Mino T, Yamashita N, Kobayashi M (1996) Interleukin-4 inhibits prostaglandin E2 production by freshly prepared adherent rheumatoid synovial cells via inhibition of biosynthesis and gene expression of cyclo-oxygenase II but not of cyclo-oxygenase I. Ann Rheum Dis 55:375
-
(1996)
Ann Rheum Dis
, vol.55
, pp. 375
-
-
Sugiyama, E.1
Taki, H.2
Kuroda, A.3
Mino, T.4
Yamashita, N.5
Kobayashi, M.6
-
83
-
-
0027363250
-
Binding of cytokines to pharmaceutically prepared human immunoglobulin
-
Svenson M, Hensen MB, Bendtzen K (1993) Binding of cytokines to pharmaceutically prepared human immunoglobulin. J Clin Invest 92:2533
-
(1993)
J Clin Invest
, vol.92
, pp. 2533
-
-
Svenson, M.1
Hensen, M.B.2
Bendtzen, K.3
-
84
-
-
7844236289
-
Course and severity of mouse collagen-induced arthritis is associated with distinct patterns of cytokine expression
-
Thornton S, Duwel LE, Hirsch R (1997) Course and severity of mouse collagen-induced arthritis is associated with distinct patterns of cytokine expression. Arthritis Rheum 40:S275
-
(1997)
Arthritis Rheum
, vol.40
-
-
Thornton, S.1
Duwel, L.E.2
Hirsch, R.3
-
85
-
-
0029925484
-
Prevention and reversal of cartilage degradation in rheumatoid arthritis by interleukin-10 and interleukin-4
-
Van Roon JAG, van Roy JLAM, Gmelig-Meyling FHJ, Lafeber FPJG, Bijlsma JWJ (1996) Prevention and reversal of cartilage degradation in rheumatoid arthritis by interleukin-10 and interleukin-4. Arthritis Rheum 39:829
-
(1996)
Arthritis Rheum
, vol.39
, pp. 829
-
-
Van Roon, J.A.G.1
Van Roy, J.L.A.M.2
Gmelig-Meyling, F.H.J.3
Lafeber, F.P.J.G.4
Bijlsma, J.W.J.5
-
86
-
-
0029959940
-
Interleukin-10 inhibition of the progression of established collagen-induced arthritis
-
Walmsley M, Katsikis PD, Abney E, Parry S, Williams RO, Maini RN, Feldmann M (1995) Interleukin-10 inhibition of the progression of established collagen-induced arthritis. Arthritis Rheum 39:495
-
(1995)
Arthritis Rheum
, vol.39
, pp. 495
-
-
Walmsley, M.1
Katsikis, P.D.2
Abney, E.3
Parry, S.4
Williams, R.O.5
Maini, R.N.6
Feldmann, M.7
-
87
-
-
0028844315
-
The intracellular IL-1 receptor antagonist alters IL-1-inducible gene expression without blocking exogenous signaling by IL-1β
-
Watson JM, Lofquist aK, Rinehart CA, Olsen JC, Makarov SS, Kaufman DG, Haskill JS (1995) The intracellular IL-1 receptor antagonist alters IL-1-inducible gene expression without blocking exogenous signaling by IL-1β. J Immunol 155:4467
-
(1995)
J Immunol
, vol.155
, pp. 4467
-
-
Watson, J.M.1
Lofquist, A.K.2
Rinehart, C.A.3
Olsen, J.C.4
Makarov, S.S.5
Kaufman, D.G.6
Haskill, J.S.7
-
88
-
-
0027371372
-
The effect of an interleukin-1 receptor antagonist protein on type II collagen-induced arthritis and antigen-induced arthritis in mice
-
Wooley PH, Whalen JD, Chapman DL, Burger AE, Richard KA, Aspar DG, Staite ND (1993) The effect of an interleukin-1 receptor antagonist protein on type II collagen-induced arthritis and antigen-induced arthritis in mice. Arthritis Rheum 36:1305
-
(1993)
Arthritis Rheum
, vol.36
, pp. 1305
-
-
Wooley, P.H.1
Whalen, J.D.2
Chapman, D.L.3
Burger, A.E.4
Richard, K.A.5
Aspar, D.G.6
Staite, N.D.7
-
89
-
-
0030611595
-
IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK
-
Woronicz JD, Gao X, Cao Z, Rothe M, Goeddel DV (1997) IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK. Science 278:866
-
(1997)
Science
, vol.278
, pp. 866
-
-
Woronicz, J.D.1
Gao, X.2
Cao, Z.3
Rothe, M.4
Goeddel, D.V.5
-
90
-
-
0030063832
-
Autoimmune manifestations in the transforming growth factor-beta I knockout mouse
-
Yaswen L, Kulkarni AB, Fredrickson T, Mittleman B, Schiffman R, Payne S, Longenecker G, Mozes E, Karlson S (1996) Autoimmune manifestations in the transforming growth factor-beta I knockout mouse. Blood 87:1439
-
(1996)
Blood
, vol.87
, pp. 1439
-
-
Yaswen, L.1
Kulkarni, A.B.2
Fredrickson, T.3
Mittleman, B.4
Schiffman, R.5
Payne, S.6
Longenecker, G.7
Mozes, E.8
Karlson, S.9
|