Prevention and reversal of cartilage degradation in rheumatoid arthritis by interleukin-10 and interleukin-4

Arthritis and Rheumatism

Volumn 39, Issue 5, 1996, Pages 829-835

  Van Roon, Joel A G ^a   Van Roy, Johanna L A M ^a   Gmelig Meyling, Frits H J ^a   Lafeber, Floris P J G ^a   Bijlsma, Johannes W J ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 4;

ADULT; AGED; ANTIBODY PRODUCTION; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE DEGENERATION; CELL STIMULATION; CHRONIC DISEASE; CLINICAL ARTICLE; EXTRACELLULAR MATRIX; FEMALE; HUMAN; MALE; MONONUCLEAR CELL; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; RHEUMATOID ARTHRITIS; SYNOVITIS;

ADULT; AGED; AGED, 80 AND OVER; ARTHRITIS, RHEUMATOID; CARTILAGE, ARTICULAR; CULTURE MEDIA, CONDITIONED; FEMALE; HUMANS; INTERLEUKIN-1; INTERLEUKIN-10; INTERLEUKIN-4; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; MONOCYTES; PROTEOGLYCANS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0029925484     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.1780390516     Document Type: Article

References (37)

1. Saxne T, Palldino MA Jr. Heinegård D, Talal N, Wollheim FA: Detection of tumor necrosis factor α but not tumor necrosis β in rheumatoid arthritis synovial fluid and serum. Arthritis Rheum 31:1041-1045, 1988
2. Chu CQ, Field M, Feldmann M, Maini RN: Localization of tumor necrosis factor a in the synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis. Arthritis Rheum 34:1125-1132, 1991
3. Noun AME, Panayi GS, Goodman SM: Cytokines and chronic inflammation of rheumatic disease. I. The presence of IL-1 in synovial fluids. Clin Exp Immunol 55:295-302, 1984
4. Miyasaka N, Sato K, Goto M, Sasano M, Natsuyama M, Inoue K, Nishioka K: Augmented interleukin-1 production and HLA-DR expression in the synovium of rheumatoid arthritis patients: possible involvement in joint destruction. Arthritis Rheum 31:480-486. 1988
5. Sipe JD, Martel-Pelletier J, Otterness IG, Pelletier JP: Cytokine reduction in the treatment of joint conditions. Med Inflamm 3:243-256, 1994
6. Wilbrink B, Holewijn M, Bijlsma JWJ, van Roy JLAM, den Otter W, van Eden W: Suppression of human cartilage proteoglycan synthesis by rheumatoid synovial fluid mononuclear cells activated with mycobacterial 60-kd heat-shock protein. Arthritis Rheum 36:514-518, 1993
7. Van der Veen MJ, Scheven BAA, van Roy JLAM, Damen CA, Lafeber FPJG, Bijlsma JWJ: In vitro effects of methotrexate on human articular cartilage and bone-derived osteoblasts. Br J Rheumatol (in press)
8. De Waal Malefyt R, Yssel H, Roncarolo MG, Spits H, de Vries JE: Interleukin-10. Curr Opin Immunol 4:314-320, 1992
9. Moore KW, O'Garra A, de Waal Malefyt R, Vieira P, Mosmann TR: Interleukin-10. Annu Rev Immunol 11:165-190, 1993
10. Del Prete G, de Carli M, Almerigogna F, Grazia Giudizi M, Biagiotti R, Romagnani S: Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T-cell clones and inhibits their antigen-specific proliferation and cytokine production. J Immunol 150:353-360, 1993
11. De Waal Malefyt R, Abrams J, Brunnett B, Figdor CG, de Vries JE: Interleukin-10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 174:1209-1220, 1991
12. Katsikis PD, Chu CQ, Brennan FM, Maini RN, Feldmann M: Immunoregulatory role of interleukin-10 in rheumatoid arthritis. J Exp Med 179:1517-1527, 1994
13. LLorente L, Richaud-Patin Y, Fior R, Alcocer-Varela J, Wijdenes J, Morel Fourrier B, Galanaud P, Emile D: In vivo production of interleukin-10 by non-T cells in rheumatoid arthntis, Sjögren's syndrome, and systemic lupus erythematosus. Arthritis Rheum 37:1647-1655, 1994
14. Cush JJ, Splawski JB, Thomas R, McFarlin JE, Schulze-Koops H, Davis LS, Fujita K, Lipsky PE: Elevated interteukin-10 levels in patients with rheumatoid arthritis. Arthritis Rheum 38:96-104, 1995
15. Mosmann TR, Cherwinski H, Bond M, Giedlin MA, Coffman RL: Two types of murine helper T-cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 136:2348-2357, 1986
16. Del Prete GF, De Carli M, Mastromauro C, Macchia D, Biagiotti R, Ricci M, Romagnani S: Purified protein derivative of Mycobacterium tuberculosis and exretory-secretory antigens of Toxocara canis expand in vitro human T-cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production. J Clin Invest 88:346-350, 1991
17. Waalen K, Sioud M, Natvig JB, Forre O: Spontaneous in vivo gene transcription of interleukin-2, interleukin-3, interleukin-4, interleukin-6, interferon-gamma, interleukin-2 receptor (CD25) and proto-oncogene c-myc rheumatoid synovial T lymphocytes. Scand J Immunol 36:865-873, 1992
18. Schlaak JF, Pfers I, Meyer zum Buschenfelde KH, Hermann E: Detection of IL-1α, IL-1β, 1L-4, IL-6, IL-8, IL-10, IL-12/p40, IFN-γ, TNF-α and TGF-β in the synovial fluid of patients with osteoarthritis, rheumatoid arthritis and miscellaneous other forms of arthritis (abstract). Clin Rheumatol 14:236, 1995
19. Taylor R, Xie C, Beckenbaugh R, Goronzy J, Weynand C: Disease specific lymphokine pattern in rheumatoid arthritis: selective modulation by methotrexate (abstract). Arthritis Rheum (suppl 9) 37:8277, 1994
20. Quayle AJ, Chomarat P, Miossec P, Kjeldsen-Kragh J, Førre Ø, Natvig JB: Rheumatoid inflammatory T-cell clones express mostly Th1 but also Th2 and mixed (Th0-like) cytokine patterns. Scand J Immunol 38:75-82, 1993
21. Briolay J, Dechanet J, Blanchard D, Banchereau J, Miossec P: IL-4 inhibits polyclonal immunoglobulin secretion and cytokine production by peripheral blood mononuclear cells from rheumatoid arthritis patients. J Clin Immunol 12:36-44, 1992
22. Miossec P, Naviliat M, Dupuy D'Angeac A, Sany J, Banchereau J: Low levels of interleukin-4 and high levels of transforming growth factor β in rheumatoid synovitis. Arthritis Rheum 33:1180-1187, 1990
23. Essner R, Rhoades K, McBride WH, Morton DL, Economou JS: IL-4 down-regulates IL-1 and TNF gene expression in human monocytes. J Immunol 142:3857-3861, 1992
24. Hart PH, Ahern MJ, Jones CA, Jones KL, Smith MD, Finlay-Jones JJ: Synovial fluid macrophages differ in their responses to IL-4. J Immunol 6:3370-3380, 1993
25. Miossec P, Briolay J, Dechanet J, Wijdenes J, Martinez-Valdez H. Banchereau J: Inhibition of the production of proinflammatory cytokines and immunoglobulins by interleukin-4 in an ex vivo model of rheumatoid arthritis. Arthritis Rheum 35:874-883, 1992
26. Oswald IP, Gazzinelli RT, Sher A, James SL: IL-10 synergizes with IL-4 and transforming growth factor-β to inhibit macrophage cytotoxic activity. J Immunol 148:3578-3582, 1992
27. Romagnani S: Lymphokine production by human T-cells in disease states. Annu Rev Immunol 12:227-257, 1994
28. Powrie F, Coffman RL: Cytokine regulation of T-cell function: potential for therapeutic intervention. Immunol Today 270:270-274, 1993
29. Miltenburg AMM, van Laar JM, De Kuiper R, Daha MR, Breedveld FC: T-cells from human rheumatoid synovial membrane functionally represent the Th1 subset. Scand J Immunol 35: 603-610, 1992
30. Simon AK, Seipelt E, Sieper J: Divergent T-cell cytokine patterns in inflammatory arthritis. Proc Natl Acad Sci USA 91:8562-8566, 1994
31. Van Roon JAG, van Roy JLAM, Duits A, Lafeber FPJG, Bijlsma JWJ: Proinflammatory cytokine production and cartilage damage due to rheumatoid synovial T-helper-1 activation is inhibited by interleukin-4. Ann Rheum Dis 54:836-840, 1995
32. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR. Liang MH, Luthra HS, Medsger TA Jr, Mitchell DM, Neustadt DH, Pinals RS, Schaller JG, Sharp JT, Wilder RL, Hunder GG: The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315-324, 1988
33. Lafeber FPJG, van der Kraan PM, van Roy JLAM, Huber-Bruning O, Bijlsma JWJ: Articular cartilage explant culture: an appropriate in vitro system to compare osteoarthritc and normal human cartilage. Conn Tissue Res 29:287-299, 1993
34. Withman P: The quantitative measurement of alcian blue glycoseaminoglycan complexes. J Biochem 131:343-350, 1973
35. Lebsack ME, Paul CC, Martindale JJ, Catalano MA: A dose-and regimen-ranging study of IL-1 receptor antagonist in patients with rheumatoid arthritis (abstract). Arthritis Rheum 39 (suppl 9):S39, 1993
36. Elliot MJ, Maini RN, Feldmann M, Kalden JR, Antoni C, Smolen JS, Leeb B, Breedveld FC, Macfarlane JD, Bijl H, Woody JN: Randomized double-blind comparison of chimeric monoclonal antibody to tumor necrosis factor a (cA2) versus placebo in rheumatoid arthritis. Lancet 344:1105-1110, 1994
37. Shingu M, Miyauchi S, Nagai Y, Yasatake C, Hone K: The role of IL-4 and IL-6 in IL-1-dependent cartilage matrix degradation. Br J Rheumatol 34:101-106, 1995