Collagen induced arthritis: Reversal by mercaptoethylguanidine, a novel antiinflammatory agent with a combined mechanism of action

Journal of Rheumatology

Volumn 25, Issue 9, 1998, Pages 1785-1793

  Brahn, Ernest ^a   Banquerigo, Mona Lisa ^b   Firestein, Gary S ^c   Boyle, David L ^d   Salzman, Andrew L ^e   Szabó, Csaba ^e,f  

^a Department of Medicine ^*

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Division of Rheumatology

^d UNIVERSITY OF CALIFORNIA   (United States)

^e Children's Hospital Medical Center

^f CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Arthritis; Collagenase; Free radical; Inflammation superoxide; Tumor necrosis factor

Indexed keywords

1 (2 MERCAPTOETHYL)GUANIDINE; ANTIINFLAMMATORY AGENT; COLLAGEN; COLLAGENASE; FREE RADICAL; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; PROSTAGLANDIN SYNTHASE; STROMELYSIN; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; NONHUMAN; PRIORITY JOURNAL; RADIODIAGNOSIS; RAT; SCORING SYSTEM;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS; COLLAGEN; COLLAGENASES; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; GUANIDINES; MATRIX METALLOPROTEINASE 3; NITRATES; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; SYNOVIAL MEMBRANE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031728092     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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