메뉴 건너뛰기




Volumn 3, Issue 10, 1997, Pages 1096-1101

GLUT4 heterozygous knockout mice develop muscle insulin resistance and diabetes

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER; INSULIN;

EID: 0030839435     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1097-1096     Document Type: Article
Times cited : (301)

References (30)
  • 1
    • 0024026298 scopus 로고
    • The triumvirate: β-cell, muscle, liver: a collusion responsible for NIDDM (Lilly Lecture 1987)
    • DeFronzo, R.A. The triumvirate: β-cell, muscle, liver: A collusion responsible for NIDDM (Lilly Lecture 1987). Diabetes 37, 667-687 (1988).
    • (1988) Diabetes , vol.37 , pp. 667-687
    • DeFronzo, R.A.1
  • 2
    • 0001575172 scopus 로고
    • Epidemiology of diabetes mellitus
    • (eds. Rifkin, H. & Porte, D., Jr.) Elsevier Science, New York
    • Bennett, P.H. Epidemiology of diabetes mellitus. in Diabetes Mellitus: Theory and Practice, 4th edn. (eds. Rifkin, H. & Porte, D., Jr.) 357-377 (Elsevier Science, New York, 1991).
    • (1991) Diabetes Mellitus: Theory and Practice, 4th Edn. , pp. 357-377
    • Bennett, P.H.1
  • 3
    • 0028152377 scopus 로고
    • Facilitative glucose transporters
    • Mueckler, M. Facilitative glucose transporters. Eur. J. Biochem. 219, 713-725 (1994).
    • (1994) Eur. J. Biochem. , vol.219 , pp. 713-725
    • Mueckler, M.1
  • 5
    • 1842419225 scopus 로고
    • A glucose transport protein expressed predominantly in insulin-responsive tissues
    • Charron, M.J., Brosius, F.C., III, Alper, S.L. & Lodish, H.F. A glucose transport protein expressed predominantly in insulin-responsive tissues. Proc Natl. Acad. Sci. USA 86, 2535-2539 (1989).
    • (1989) Proc Natl. Acad. Sci. USA , vol.86 , pp. 2535-2539
    • Charron, M.J.1    Brosius III, F.C.2    Alper, S.L.3    Lodish, H.F.4
  • 6
    • 0019762341 scopus 로고
    • The effect of insulin on the disposal of intravenous glucose: Results from indirect calorimetry and hepatic and femoral venous catheterization
    • DeFronzo, R.A. et al. The effect of insulin on the disposal of intravenous glucose: Results from indirect calorimetry and hepatic and femoral venous catheterization. Diabetes 30, 1000-1007 (1981).
    • (1981) Diabetes , vol.30 , pp. 1000-1007
    • DeFronzo, R.A.1
  • 7
    • 0025176936 scopus 로고
    • Identification of an intracellular pool of glucose transporters from basal and insulin-stimulated rat skeletal muscle
    • Hirshman, M.F., Goodyear, L.J., Wardzala, L.J., Horton, E.D. & Horton, E.S. Identification of an intracellular pool of glucose transporters from basal and insulin-stimulated rat skeletal muscle. J. Biol. Chem. 265, 987-991 (1990).
    • (1990) J. Biol. Chem. , vol.265 , pp. 987-991
    • Hirshman, M.F.1    Goodyear, L.J.2    Wardzala, L.J.3    Horton, E.D.4    Horton, E.S.5
  • 8
    • 0025131847 scopus 로고
    • Recruitment of GLUT4 glucose transporters by insulin in diabetic rat skeletal muscle
    • Klip, A. et al. Recruitment of GLUT4 glucose transporters by insulin in diabetic rat skeletal muscle. Biochem. Biophys. Res. Commun. 172, 728-736 (1990).
    • (1990) Biochem. Biophys. Res. Commun. , vol.172 , pp. 728-736
    • Klip, A.1
  • 10
    • 0027463916 scopus 로고
    • Glucose transport in human skeletal muscle: The in vivo response to insulin
    • Bonadonna, R.C. et al. Glucose transport in human skeletal muscle: The in vivo response to insulin. Diabetes 42, 191-198 (1993).
    • (1993) Diabetes , vol.42 , pp. 191-198
    • Bonadonna, R.C.1
  • 11
    • 0021341824 scopus 로고
    • Glucose transport and metabolism in the perfused hindquarters of lean and obese-hyperglycemic (db/db) mice: Effects of insulin and electrical stimulation
    • Chan, T.M. & Tatoyan, A. Glucose transport and metabolism in the perfused hindquarters of lean and obese-hyperglycemic (db/db) mice: Effects of insulin and electrical stimulation. Biochim. Biophys. Acta 798, 325-332 (1984).
    • (1984) Biochim. Biophys. Acta , vol.798 , pp. 325-332
    • Chan, T.M.1    Tatoyan, A.2
  • 12
    • 0023606655 scopus 로고
    • Development of obesity in Zucker rats: Early insulin resistance in muscles but normal sensitivity in white adipose tissue
    • Penicaud, L. et al. Development of obesity in Zucker rats: Early insulin resistance in muscles but normal sensitivity in white adipose tissue. Diabetes 36, 626-631 (1987).
    • (1987) Diabetes , vol.36 , pp. 626-631
    • Penicaud, L.1
  • 13
  • 14
    • 0029775874 scopus 로고    scopus 로고
    • Insulin action on glucose transport and plasma membrane GLUT4 content in skeletal muscle from patients with NIDDM
    • Zierath, J.R. et al. Insulin action on glucose transport and plasma membrane GLUT4 content in skeletal muscle from patients with NIDDM. Diabetologia 39, 1180-1189 (1996).
    • (1996) Diabetologia , vol.39 , pp. 1180-1189
    • Zierath, J.R.1
  • 15
    • 0026502258 scopus 로고
    • Alterations in glucose transporter expression and function in diabetes: Mechanisms for insulin resistance
    • Kahn, B.B. Alterations in glucose transporter expression and function in diabetes: Mechanisms for insulin resistance. J. Cell Biochem. 48, 122-128 (1992).
    • (1992) J. Cell Biochem. , vol.48 , pp. 122-128
    • Kahn, B.B.1
  • 16
    • 0029148426 scopus 로고
    • Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4
    • Katz, E.B., Stenbit, A.E., Hatton, K., DePinho, R. & Charron, M.J. Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4. Nature 377, 151-155 (1995).
    • (1995) Nature , vol.377 , pp. 151-155
    • Katz, E.B.1    Stenbit, A.E.2    Hatton, K.3    DePinho, R.4    Charron, M.J.5
  • 17
    • 0018139377 scopus 로고
    • Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
    • Coleman, D.L. Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 14, 141-148 (1978).
    • (1978) Diabetologia , vol.14 , pp. 141-148
    • Coleman, D.L.1
  • 18
    • 0014807533 scopus 로고
    • The influence of age and dietary conditions on diabetes in the db mouse
    • Wyse, B.M. & Dulin, W.E. The influence of age and dietary conditions on diabetes in the db mouse. Diabetologia 6, 268-273 (1970).
    • (1970) Diabetologia , vol.6 , pp. 268-273
    • Wyse, B.M.1    Dulin, W.E.2
  • 19
    • 0015317771 scopus 로고
    • Hyperinsulinemia and insulin resistance in genetically obese rats
    • York, D.A., Steinke, J. & Bray, G.A. Hyperinsulinemia and insulin resistance in genetically obese rats. Metab. Clin. Exp. 21, 277-284 (1972).
    • (1972) Metab. Clin. Exp. , vol.21 , pp. 277-284
    • York, D.A.1    Steinke, J.2    Bray, G.A.3
  • 20
    • 0018944351 scopus 로고
    • Clinical and morphological features of human hypertensive-diabetic cardiomyopathy
    • Factor, S.M., Minase, T. & Sonnenblick, E.H. Clinical and morphological features of human hypertensive-diabetic cardiomyopathy. Am. Heart J. 99, 446-458 (1980).
    • (1980) Am. Heart J. , vol.99 , pp. 446-458
    • Factor, S.M.1    Minase, T.2    Sonnenblick, E.H.3
  • 21
    • 0025148503 scopus 로고
    • A comparison of the pathological spectrum of hypertensive, diabetic, and hypertensive-diabetic heart disease
    • van Hoeven, K.H. & Factor, S.M. A comparison of the pathological spectrum of hypertensive, diabetic, and hypertensive-diabetic heart disease. Circulation 82, 848-855 (1990).
    • (1990) Circulation , vol.82 , pp. 848-855
    • Van Hoeven, K.H.1    Factor, S.M.2
  • 22
    • 0029911864 scopus 로고    scopus 로고
    • Diverse effects of Glut 4 ablation on glucose uptake and glycogen synthesis in red and white skeletal muscle
    • Stenbit, A.E. et al. Diverse effects of Glut 4 ablation on glucose uptake and glycogen synthesis in red and white skeletal muscle. J. Clin. Invest. 98, 629-634 (1996).
    • (1996) J. Clin. Invest. , vol.98 , pp. 629-634
    • Stenbit, A.E.1
  • 23
    • 0038155702 scopus 로고    scopus 로고
    • Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles
    • Bruning, J.C. et al. Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles. Cell 88, 561-572 (1997).
    • (1997) Cell , vol.88 , pp. 561-572
    • Bruning, J.C.1
  • 24
    • 0027520656 scopus 로고
    • The diabetogenes concept of NIDDM
    • (eds. Ostenson, C.G. et al.) Plenum, New York
    • De Meyts, P. The diabetogenes concept of NIDDM. in New Concepts in the Pathogenesis of NIDDM (eds. Ostenson, C.G. et al.) 89-100 (Plenum, New York, 1993).
    • (1993) New Concepts in the Pathogenesis of NIDDM , pp. 89-100
    • De Meyts, P.1
  • 25
    • 0029842180 scopus 로고    scopus 로고
    • The metabolic consequences of altered glucose transporter expression in transgenic mice
    • Katz, E.B., Burcelin, R., Tsao, T.S., Stenbit, A.E. & Charron, M.J. The metabolic consequences of altered glucose transporter expression in transgenic mice. J. Mol. Med. 74, 639-652 (1996).
    • (1996) J. Mol. Med. , vol.74 , pp. 639-652
    • Katz, E.B.1    Burcelin, R.2    Tsao, T.S.3    Stenbit, A.E.4    Charron, M.J.5
  • 26
    • 0011817740 scopus 로고
    • Obesity and diabetes mellitus
    • (eds. Rifkin, H. & Porte, D., Jr.) Elsevier Science, New York
    • Norton, E.S. & Jeanrenaud, B. Obesity and diabetes mellitus. in Diabetes Mellitus: Theory and Practice, 4th edn. (eds. Rifkin, H. & Porte, D., Jr.) 457-465 (Elsevier Science, New York, 1991).
    • (1991) Diabetes Mellitus: Theory and Practice, 4th Edn. , pp. 457-465
    • Norton, E.S.1    Jeanrenaud, B.2
  • 27
    • 0017904216 scopus 로고
    • Determinations of adipose cell size and number in suspensions of isolated rat and human adipose cells
    • Cushman, S.W. & Salans, L.B. Determinations of adipose cell size and number in suspensions of isolated rat and human adipose cells. J. Lipid Res. 19, 269-273 (1978).
    • (1978) J. Lipid Res. , vol.19 , pp. 269-273
    • Cushman, S.W.1    Salans, L.B.2
  • 28
    • 0024352305 scopus 로고
    • Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic rats
    • Kahn, B.B., Charron, M.J. & Lodish, H.F. Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic rats. J. Clin. Invest. 84, 404-411 (1991).
    • (1991) J. Clin. Invest. , vol.84 , pp. 404-411
    • Kahn, B.B.1    Charron, M.J.2    Lodish, H.F.3
  • 29
    • 0029091809 scopus 로고
    • WW6: An embryonic stem cell line with an inert genetic marker that can be traced in chimeras
    • Ioffe, E. et al. WW6: An embryonic stem cell line with an inert genetic marker that can be traced in chimeras. Proc. Natl. Acad. Sci. USA 92, 7357-7361 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7357-7361
    • Ioffe, E.1
  • 30
    • 0025859983 scopus 로고
    • Insulin and nonhydrolyzable GTP analogs induce translocation of GLUT4 to the plasma membrane in alpha-toxin-permeabilized rat adipose cells
    • Baldini, G., Holman, R., Charron, M.J & Lodish, H.F. Insulin and nonhydrolyzable GTP analogs induce translocation of GLUT4 to the plasma membrane in alpha-toxin-permeabilized rat adipose cells. J. Biol Chem. 266, 4037-4040 (1991).
    • (1991) J. Biol Chem. , vol.266 , pp. 4037-4040
    • Baldini, G.1    Holman, R.2    Charron, M.J.3    Lodish, H.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.