Chapter 27. Roles of Caspases in Inflammation and Apoptosis: Prospects as Drug Discovery Targets

Annual Reports in Medicinal Chemistry

Volumn 33, Issue C, 1998, Pages 273-282

  Talanian, Robert V ^a   Allen, Hamish J ^a  

^a BASF Bioresearch Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000027829     PISSN: 00657743     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-7743(08)61092-1     Document Type: Chapter

References (104)

1. Alnemri E.S., Livingston D.J., Nicholson D.W., Salvesen G., Thornberry N.A., Wong W.W., and Yuan J. Cell 87 (1996) 171
2. Thornberry N.A., Rano T.A., Peterson E.P., Rasper D.M., Timkey T., Garcia-Calvo M., Houtzager V.M., Nordstrom P.A., Roy S., Vaillancourt J.P., Chapman K.T., and Nicholson D.W. J. Biol. Chem. 272 (1997) 17907-17911
3. Talanian R.V., Quinlan C., Trautz S., Hackett M.C., Mankovich J.A., Banach D., Ghayur T., Brady K.D., and Wong W.W. J. Biol. Chem. 272 (1997) 9677-9682
4. Rotonda J., Nicholson D.W., Fazil K.M., Gallant M., Gareau Y., Labelle M., Peterson E.P., Rasper D.M., Ruel R., Vaillancourt J.P., Thornberry N.A., and Becker J.W. Nature Struct. Biol. 3 (1996) 619-625
5. Walker N.P.C., Talanian R.V., Brady K.D., Dang L.C., Bump N.J., Ferenz C.R., Franklin S., Ghayur T., Hackett M.C., Hammill L.D., Herzog L., Hugunin M., Houy W., Mankovich J.A., McGuiness L., Orlewicz E., Paskind M., Pratt C.A., Reis P., Summani A., Terranova M., Welch J.P., Xiong L., Möller A., Tracey D.E., Kamen R., and Wong W.W. Cell 78 (1994) 343-352
6. Wilson K.P., Black J.-A.F., Thomson J.A., Kim E.E., Griffith J.P., Navia M.A., Murcko M.A., Chambers S.P., Aldape R.A., Raybuck S.A., and Livingston D.J. Nature 370 (1994) 270-275
7. Tamura T., Ishihara M., Lamphier M.S., Tanaka N., Oishi I., Aizawa S., Matsuyama T., Mak T.W., Taki S., and Taniguchi T. Nature 376 (1995) 596-599
8. Kumar A., Commane M., Flickinger T.W., Horvath C.M., and Stark G.R. Science 278 (1997) 1630-1632
9. Chin Y.E., Kitagawa M., Kuida K., Flavell R.A., and Fu X.-Y. Mol. Cell. Biol. 17 (1997) 5328-5337
10. Miossec C., Decoen M.-C., Durand L., Fassy F., and Diu- Hercend A. Eur. J. Immunol. 26 (1996) 1032-1042
11. Talanian R.V., Dang L.C., Ferenz C.R., Hackett M.C., Mankovich J.A., Welch J.P., Wong W.W., and Brady K.D. J. Biol. Chem. 271 (1996) 21853-21858
12. Dang L.C., Talanian R.V., Banach D., Hackett M.C., Gilmore J.L., Hays S.J., Mankovich J.A., and Brady K.D. Biochemistry 35 (1996) 14910-14916
13. Wang S., Miura M., Jung Y.-k., Zhu H., Li E., and Yuan J. Cell 92 (1998) 501-509
14. Gu Y., Wu J., Faucheu C., Lalanne J.-L., Diu A., Livingston D.J., and Su M.S.-S. EMBO J. 14 (1923) 1995
15. Li J., Billiar T.R., Talanian R.V., and Kim Y.M. Biochem. Biophys. Res. Comm. 240 (1997) 419-424
16. Melino G., Bernassola F., Knight R.A., Tiziana Corasaniti M., Nisticò G., and Finazzi-Agrò A. Nature 388 (1997) 432-433
17. Mohr S., Zech B., Lapetina E.G., and Brüne B. Biochem. Biophys. Res. Comm. 238 (1997) 387-391
18. Ogura T., Tatemichi M., and Esumi H. Biochem. Biophys. Res. Comm. 236 (1997) 365-369
19. Saavedra J.E., Billiar T.R., Williams D.L., Kim Y.-M., Watkins S.C., and Keefer L.K. J. Med. Chem. 40 (1947) 1997
20. Dimmeler S., Haendeler J., Nehls M., and Zeiher A.M. J. Exp. Med. 185 (1997) 601-607
21. Kim Y.-M., Talanian R.V., and Billiar T.R. J. Biol. Chem. 272 (1997) 31138-31148
22. Mannick J.B., Miao X.Q., and Stamler J.S. J. Biol. Chem. 272 (1997) 24125-24128
23. Clem R.J., Fechheimer M., and Miller L.K. Science 254 (1991) 1388-1390
24. Ray C.A., Black R.A., Kronheim S.R., Greenstreet T.A., Sleath P.R., Salvesen G.S., and Pickup D.J. Cell 69 (1992) 597-604
25. Bump N.J., Hackett M., Hugunin M., Seshagiri S., Brady K., Chen P., Ferenz C., Franklin S., Ghayur T., Li P., Licari P., Mankovich J., Shi L., Greenberg A.H., Miller L.K., and Wong W.W. Science 269 (1995) 1885-1888
26. Chen P., Tian J., Kovesdi I., and Bruder J.T. J. Biol. Chem. 273 (1998) 5815-5820
27. Crook N.E., Clem R.J., and Miller L.K. J. Virol. 67 (1993) 2168-2174
28. Deveraux Q.L., Takahashi R., Salvesen G.S., and Reed J.C. Nature 388 (1997) 300-304
29. Roy N., Deveraux Q.L., Takahashi R., Salvesen G.S., and Reed J.C. EMBO J. 16 (1997) 6914-6925
30. Hu S., Vincenz C., Ni J., Gentz R., and Dixit V.M. J. Biol. Chem. 272 (1997) 17255-17257
31. Cerretti D.P., Kozlosky C.J., Mosley B., Nelson N., Van N.K., Greenstreet T.A., March C.J., Kronheim S.R., Druck T., Cannizzaro L.A., Huebner K., and Black R.A. Science 256 (1992) 97-100
32. Thornberry N.A., Bull H.G., Calaycay J.R., Chapman K.T., Howard A.D., Kostura M.J., Miller D.K., Molineaux S.M., Weidner J.R., Aunins J., Elliston K.O., Ayala J.M., Casano F.J., Chin J., Ding G.J.-F., Egger L.A., Gaffney E.P., Limjuco G., Palyha O.C., Raju S.M., Rolando A.M., Salley J.P., Yamin T.-T., Lee T.D., Shively J.E., MacCross M., Mumford R.A., Schmidt J.A., and Tocci M.J. Nature 356 (1992) 768-774
33. Li P., Allen H., Banerjee S., Franklin S., Herzog L., Johnston C., McDowell J., Paskind M., Rodman L., Salfeld J., Towne E., Tracey D., Wardwell S., Wei F.-Y., Wong W., Kamen R., and Seshadri T. Cell 80 (1995) 401-411
34. Kuida K., Lippke J.A., Ku G., Harding M.W., Livingston D.J., Su M.S.-S., and Flavell R.A. Science 267 (1995) 2000-2003
35. Howard A.D., Kostura M.J., Thornberry N., Ding G.J., Limjuco G., Weidner J., Salley J.P., Hogquist K.A., Chaplin D.D., Mumford R.A., Schmidt J.A., and Tocci M.J. J. Immunol. 147 (1991) 2964-2969
36. Kobayashi Y., Yamamoto K., Saido T., Kawasaki H., Oppenheim J.J., and Matsushima K. Proc. Natl. Acad. Sci. USA 87 (1990) 5548-5552
37. Carruth L.M., Demczuk S., and Mizel S.B. J. Biol. Chem. 266 (1991) 12162-12167
38. Ghayur T., Banerjee S., Hugunin M., Butler D., Herzog L., Carter A., Quintal L., Sekut L., Talanian R., Paskind M., Wong W., Kamen R., Tracey D., and Allen H. Nature 386 (1997) 619-623
39. Gu Y., Kuida K., Tsutsui H., Ku G., Hsiao K., Fleming M.A., Hayashi N., Higashino K., Okamura H., Nakanishi K., Kurimoto M., Tanimoto T., Flavell R.A., Sato V., Harding M.W., Livingston D.J., and Su M.S.-S. Science 275 (1997) 206-209
40. Okamura H., Tsutsui H., Komatsu T., Yutsudo M., Hakura A., Tanimoto T., Torigoe K., Okura T., Nukada Y., Hattori K., Akita K., Namba M., Tanabe F., Konishi K., Fukuda S., and Kurimoto M. Nature 378 (1995) 88-90
41. Zhang Y., Center D.M., Wu D.M.H., Cruikshank W.W., Yuan J., Andrews D.W., and Kornfeld H. J. Biol. Chem. 273 (1998) 1144-1149
42. Golstein P. Curr. Biol. 7 (1997) R750-R753
43. Chinnaiyan A.M., O'Rourke K., Tewari M., and Dixit V.M. Cell 81 (1995) 505-512
44. Martin D.A., Siegel R.M., Zheng L., and Lenardo M.J. J. Biol. Chem. 273 (1998) 4345-4349
45. Duan H., and Dixit V.M. Nature 385 (1997) 86-89
46. Ahmad M., Srinivasula S.M., Wang L., Talanian R.V., Litwack G., Fernandes-Alnemri T., and Alnemri E.S. Cancer Res. 57 (1997) 615-619
47. Yang X., Khosravi-Far R., Chang H.Y., and Baltimore D. Cell 89 (1997) 1067-1076
48. Talanian R.V., Yang X., Turbov J., Seth P., Ghayur T., Casiano C.A., Orth K., and Froelich C.J. J. Exp. Med. 186 (1997) 1323-1331
49. Reed J.C. Cell 91 (1997) 559-562
50. Kroemer G., Zamzami N., and Susin S.A. Immunol. Today 18 (1997) 44-51
51. Liu X., Kim C.N., Yang J., Jemmerson R., and Wang X. Cell 86 (1996) 147-157
52. Zou H., Henzel W.J., Liu X., Lutschg A., and Wang X. Cell 90 (1997) 405-413
53. Yuan J., and Horvitz H.R. Development 116 (1992) 309-320
54. Ellis H.M., and Horvitz H.R. Cell 44 (1986) 817-829
55. Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., and Wang X. Cell 91 (1997) 479-489
56. Sanghavi D.M., Thelen M., Thornberry N.A., Casciola-Rosen L., and Rosen A. FEBS Lett. 422 (1998) 179-184
57. Lindahl T., Satoh M.S., Poirier G.G., and Klungland A. Trends Biochem. Sci. 20 (1995) 405-411
58. Lazebnik Y.A., Takahashi A., Poirier G.G., Kaufmann S.H., and Earnshaw W.C. J. Cell. Sci. Suppl. 19 (1995) 41-49
59. Küpper J.-H., Müller M., Jacobson M.K., Tatsumi-Miyajima J., Coyle D.L., Jacobson E.L., and Bürkle A. Mol. Cell. Biol. 15 (1995) 3154-3163
60. Schreiber V., Hunting D., Trucco C., Gowans B., Grunwald D., de Murcia G., and Menissier de Murcia J. Proc. Natl. Acad. Sci. USA 92 (1995) 4753-4757
61. Song Q., Lees-Miller S.P., Kumar S., Zhang N., Chan D.W., Smith G.C.M., Jackson S.P., Alnemri E.S., Litwack G., Khanna K.K., and Lavin M.F. EMBO J. 15 (1996) 3238-3246
62. Casciola-Rosen L., Nicholson D.W., Chong T., Rowan K.R., Thornberry N.A., Miller D.K., and Rosen A. J. Exp. Med. 183 (1957) 1996
63. Enari M., Sakahira H., Yokoyama H., Okawa K., Iwamatsu A., and Nagata S. Nature 391 (1998) 43-50
64. Liu X., Zou H., Slaughter C., and Wang X. Cell 89 (1997) 175-184
65. Sakahira H., Enari M., and Nagata S. Nature 391 (1998) 96-99
66. Takahashi A., Alnemri E.S., Lazebnik Y.A., Fernandes-Alnemri T., Litwack G., Moir R.D., Goldman R.D., Poirier G.G., Kaufmann S.H., and Earnshaw W.C. Proc. Natl. Acad. Sci. USA 93 (1996) 8395-8400
67. Orth K., Chinnaiyan A.M., Garg M., Froelich C.J., and Dixit V.M. J. Biol. Chem. 271 (1996) 16443-16446
68. Martin S.J., O'Brien G.A., Nishioka W.K., McGahon A.J., Mahboubi A., Saido T.C., and Green D.R. J. Biol. Chem. 270 (1995) 6425-6428
69. Vanags D.M., Pörn-Ares M.I., Coppola S., Burgess D.H., and Orrenius S. J Biol. Chem. 271 (1996) 31075-31085
70. Cryns V.L., Bergeron L., Zhu H., Li H., and Yuan J. J. Biol. Chem. 271 (1996) 31277-31282
71. Nath R., Raser K.J., Stafford D., Hajimohammadreza I., Posner A., Allen H., Talanian R.V., Yuen P., Gilbertsen R.B., and Wang K.K.W. Biochem. J. 319 (1996) 683-690
72. Savill J. Br. Med. Bull. 53 (1997) 491-508
73. Martin S.J., Finucane D.M., Amarante-Mendes G.P., O'Brien G.A., and Green D.R. J. Biol. Chem. 271 (1996) 28753-28756
74. Lazebnik Y.A., Kaufmann S.H., Desnoyers S., Poirier G.G., and Earnshaw W.C. Nature 371 (1994) 346-347
75. Nicholson D.W., Ali A., Thornberry N.A., Vaillancourt J.P., Ding C.K., Gallant M., Gareau Y., Griffin P.R., Labelle M., Lazebnik Y.A., Munday N.A., Raju S.M., Smulson M.E., Yamin T.-T., Yu V.L., and Miller D.K. Nature 376 (1995) 37-43
76. Neamati N., Fernandez A., Wright S., Kiefer J., and McConkey D.J. J. Immunol. 154 (1995) 3788-3795
77. Wang X., Pai J.-t., Wiedenfeld E.A., Medina J.C., Slaughter C.A., Goldstein J.L., and Brown M.S. J. Biol. Chem. 270 (1995) 18044-18050
78. Beyaert R., Kidd V.J., Cornelis S., Van de Craen M., Denecker G., Lahti J.M., Gururajan R., Vandenabeele P., and Fiers W. J. Biol. Chem. 272 (1997) 11694-11697
79. Emoto Y., Manome Y., Meinhardt G., Kisaki H., Kharbanda S., Robertson M., Ghayur T., Wong W.W., Kamen R., Weichselbaum R., and Kufe D. EMBO J. 14 (1995) 6148-6156
80. Ghayur T., Hugunin M., Talanian R.V., Ratnofsky S., Quinlan C., Emoto Y., Pandey P., Datta R., Huang Y., Kharbanda S., Allen H., Kamen R., Wong W., and Kufe D. J. Exp. Med. 184 (1996) 2399-2404
81. Na S., Chuang T.-H., Cunningham A., Turi T.G., Hanke J.H., Bokoch G.M., and Danley D.E. J. Biol. Chem. 271 (1996) 11209-11213
82. Chen Z., Naito M., Mashima T., and Tsuruo T. Cancer Res. 56 (1996) 5224-5229
83. Kayalar C., Örd T., Testa M.P., Zhong L.-t., and Bredsen D.E. Proc. Natl. Acad. Sci. USA 93 (1996) 2234-2238
84. Jänicke R.U., Walker P.A., Lin X.Y., and Porter A.G. EMBO J. 15 (1996) 6969-6978
85. An B., and Dou Q.P. Cancer Res. 56 (1996) 438-442
86. Cryns V.L., Byun Y., Rana A., Mellor H., Lustig K.D., Ghanem L., Parker P.J., Kirschner M.W., and Yuan J. J. Biol. Chem. 272 (1997) 29449-29453
87. Brancolini C., Benedetti M., and Schneider C. EMBO J. 14 (1995) 5179-5190
88. Cheng E.H.-Y., Kirsch D.G., Clem R.J., Ravi R., Kastan M.B., Bedi A., Ueno K., and Hardwick J.M. Science 278 (1966) 1997
89. Cardone M.H., Salvesen G.S., Widmann C., Johnson G., and Frisch S.M. Cell 90 (1997) 315-323
90. Kothakota S., Azuma T., Reinhard C., Klippel A., Tang J., Chu K., McGarry T.J., Kirschner M.W., Koths K., Kwiatkowski D.J., and Williams L.T. Science 278 (1997) 294-298
91. Casciola-Rosen L.A., Miller D.K., Anhalt G.J., and Rosen A. J. Biol. Chem. 269 (1994) 30757-30760
92. Widmann C., Gibson S., and Johnson G.L. J. Biol. Chem. 273 (1998) 7141-7147
93. Dinarello C.A. Blood 87 (1996) 2095-2147
94. Tracey D. Ann. Rep. Med. Chem. 29 (1994) 205-214
95. Nicholson D.W. Nature Biotech. 14 (1996) 297-301
96. Fantuzzi G., Zheng H., Faggioni R., Benigni F., Ghezzi P., Sipe J.D., Shaw A.R., and Dinarello C.A. J. Immunol. 157 (1996) 291-296
97. Shornick L.P., De Togni P., Mariathasan S., Goellner J., Strauss-Schoenberger J., Karr R.W., Ferguson T.A., and Chaplin D.D. J. Exp. Med. 183 (1996) 1427-1436
98. Schielke G.P., Yang G.-Y., Shivers B.D., and Betz A.L. J. Cereb. Blood Flow. Metab. 18 (1998) 180-185
99. Friedlander R.M., Gagliardini V., Hara H., Fink K.B., Li W., MacDonald G., Fishman M.C., Greenberg A.H., Moskowitz M.A., and Yuan J. J. Exp. Med. 185 (1997) 933-940
100. Hara H., Friedlander R.M., Gagliardini V., Ayata C., Fink K., Huang Z., Shimizu-Sasamata M., Yuan J., and Moskowitz M.A. Proc. Natl. Acad. Sci. USA 24 (1997) 2007-2012
101. Loddick S.A., MacKenzie A., and Rothwell N.J. Neuroreport 7 (1996) 1465-1468
102. Friedlander R.M., Brown R.H., Gagliardini V., Wang J., and Yuan J. Nature 388 (1997) 31
103. Rodriguez I., Matsuura K., Ody C., Nagata S., and Vassalli P. J. Exp. Med. 184 (1996) 2067-2072
104. Kuida K., Zheng T.S., Na S., Kuan C.-y., Yang D., Karasuyama H., Rakic P., and Flavell R.A. Nature 334 (1996) 368-372